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Review

Novel approaches to fracture healing

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Pages 1573-1580 | Published online: 24 Feb 2005

Bibliography

  • EINHORN MA: Current concepts review: enhancement of fracture healing. J. Bone Joint Surg. (1995) 77A:940–955.
  • COCKIN J: Autologous bone grafting. Complications at the donor site. J. Bone Joint Surg. (1971) 53B:153.
  • DAMIEN CJ, PARSONS JR: Bone graft substitutes. J. Appl. Biomech. (1991) 2:187–298.
  • SUMMERS BN, EISENSTEIN SM: Donor site pain from the ilium: a complication of lumbar spine fusion. J. Bone Joint Surg. (1989) 71B:677–680.
  • YOUNGER EM, CHAPMAN MW: Morbidity at bone graft donor sites. J. Orthop. Trauma (1989) 3:192–195.
  • TOMFORD WW: Transmission of disease through transplantation of musculoskeletal allografts. J. Bone Joint Surg. (1995) 77A:1742–1754.
  • MELLONIG JT: Donor selection, testing and inactiva-tion of the HIV virus in freeze-dried bone allografts. Pract. Periodontics Aesthet. Dent. (1995) 7(6):13–22.
  • GREEN E, HINTON C, TRIFIT JT: The effect of decalcified bone matrix on the osteogenic potential of bone marrow. Clin. Orthop. (1986) 205:292–298.
  • NADE S, BURWELL RG: Decalcified bone as a substitutefor osteogenesis. j Bone Joint Surg. (1977) 59B:189–196.
  • CONNOLLY JF: Injectable bone marrow preparations tostimulate osteogenic repair. Clin. Orthop. (1995) 313:8–18.
  • CRANE GM, ISHAUG SL, MIKOS AG: Bone tissue engineering. Nature Med. (1995) 1:1322–1324.
  • IGNATIUS AA, CLAES LE: In vitro biocompatibility of bioresorbable polymers: poly(L, DL-lactide) and poly (L-lactide-co-glycolide). Biomaterials (1996) 17:831–839.
  • MURPHY WL, KOHN DH, MOONEY DJ: Growth of continuous bonelike mineral within porous poly (lactide-co-glycolide) scaffolds in vitro. J. Biomed. mater. Res. (2000) 50:50–58.
  • FU K, PACK DW, KLIBANOV AM, LANGER R: Visual evidence of acidic environment within degrading poly (1 actic-co-glycolic acid) (PLGA) microspheres. Pharm. Res. (2000) 17:100–106.
  • BLOCK JE, THORN MR: Clinical indications of calcium-phosphate biomaterials and related composites for orthopaedic procedures. Calcif Tissue Int. (2000) 66:234–238.
  • CORNELL CN, LANE JM, CHAPMAN M et al: Multicenter trial of collagraft as bone graft substitute. J. Orhtop. Trauma (1991) 5:1–8.
  • SHORS EC: Coralline bone graft substitutes. Orthop. North Am. (1999) 30:599–613.
  • AYERS RA, SIMSKE SJ, NUNES CR, WOLFORD LM: Long-term bone ingrowth and residual microhardness of porous block hydroxyapatite implants in humans. J. Oral Maxillofac. Surg. (1998) 56:1297–1301.
  • BUCHOLZ RW, CARLTON A, HOLMES R: Interporous hydroxyapatite as a bone graft substitute in tibial plateau fractures. Clin. Orthop. (1989) 240:53–62.
  • FRIEDENSTEIN AJ: Precursor cells of mechanocytes.Int. Rev. Cytol. (1976) 47:327–359.
  • ASHTON BA, ABDULLAH F, CANE J et al.: Characteriza-tion of cells with high alkaline phosphatase activity derived from human bone and marrow: Preliminary assessment of their osteogenicity. Bone (1985) 6:313–319.
  • PROCKOP DJ: Marrow stromal cells as stem cells for non-hematopoietic tissues. Science (1997) 276:71–74.
  • DENNIS JE, MERRIAM A, WDALLAH A, Y00 JU, JOHNSTONE B, CAPLAN Al: A quadripotential mesenchymal progenitor cell isolated from the marrow of an adult mouse. J. Bone Miner. Res. (1999) 14:700–709.
  • PLENK H, HOLLMANN K, WILFERT KH: Experimental bridging of osseous defects in rats by the implantation of Kiel bone containing fresh autologous marrow. J. Bone Joint Surg. (1972) 54B:735–743.
  • BURWELL RG: The function of bone marrow in incorporation of bone graft. Clin. Orthop. (1985) 200:125–141.
  • SALAMA R, WEISSMANN SL: The clinical use ofcombined xenografts of bone and autologous red marrow. A preliminary report. J. Bone Joint Surg. (1985) 60B:111–115.
  • GARG NK, GAUR S, SHARMA S: Percutaneous autoge-nous bone marrow grafting in 20 cases of ununited fracture. Acta. Orthop. Scand. (1993) 64:671–672.
  • CONNOLLY JF, GUSE R: Autologous bone marrow injection for delayed unions of the tibia: a preliminary report. J. Orthop. trauma (1989) 3:276–282.
  • LINDHOLM TS, URIST MR: A quantitative analysis of new bone formation by induction in composite grafts of bone marrow and bone matrix. Clin. Orthop. (1980) 150:288–300.
  • CONNOLLY JF, GUSE R, TIEDEMANN J, DEHNE R: Autolo-gous marrow injection as a substitute for operative grafting on non-unions. Clin. Orthop. (1990) 266:259–270.
  • BALK ML, BRAY J, DAY C et al: Effect of rhBMP-2 onosteogenic potential of bone marrow stromal cells from an osteogenesis imperfecta mouse. Bone (1997) 21:7–15.
  • PITTINGER MF, MACKAY AM, BECK SC et al.: Multilineagepotential of adult human mesenchymal stem cells. Science (1999) 284:143–147.
  • OYAMA M, TATLOCK A, FUKUTA S et al.: Retrovirally transduced bone marrow stromal cells isolated from a mouse model of human osteogenesis imperfecta (oim) persist in bone and retain the ability to form cartilage and bone after extended passaging. Gene Ther. (2000). (In press).
  • BRUDER SP, FOX BS: Tissue engineering of bone: cell based strategies. Clin. Orthop. Rel. Res. (1999) 367S:S68–S83.
  • WOZNEY JF, ROSEN V: Bone morphogenetic proteins and their gene expression. In: Cellular and Molecular Biology of Bone. Academic Press (1993):131–167.
  • WOZNEY JM, ROSEN V, CELESTE AJ et al.: Novel regula-tors of bone formation: molecular clones and activi-ties. Science (1988) 242:1528–1534.
  • WOZNEY JM, ROSEN V: Bone morphogenetic proteinand bone morphogenetic protein gene family in bone formation and repair. Clin. Orhtop. Rel. Res. (1998) 346:26–37.
  • REDDI AH: Initiation of fracture repair by bonemorphogenetic proteins. Clin. Orthop. Rel. Res. (1998) 355S:566–572.
  • GERHART TN, KIRKER-HEAD CA, KRIZ MJ et al. Clinical healing segmental femoral defects in sheep using recombinant human bone morphogenetic protein. Orthop. (1993) 293:317–326.
  • LEE SC, SHEA M, BATTLE MA et al.: Healing of largesegmental defects in rat femurs is aided by rhBMP-2 in PLGA matrix. J. Biomed. Mater. Res. (1994) 28:1149–1156.
  • COOK SD, WOLF MW, SALKELD SL, RUEGER DC: Effect ofrecombinant human osteogenic protein-1 on healing of segmental defects in non-human primates. J. Bone Joint Surg. (1995) 77A:734–750.
  • COOK SD, BAFFES GC et al.: The effect of recombinant human osteogenic protein-1 on healing of large segmental bone defects. J. Bone Joint Surg. (1994) 76A:827–838.
  • WINN SR, ULUDAG H, HOLLINGER J: Carrier systems for bone morphogenetic proteins. Clin. Orthop. Rel. Res. (1999) 367S:595–5106.
  • WANG DS, YAMAZAKI K, NOHTOMI K et al.: Increase of vascular endothelial growth factor mRNA expression by 1,25-dihydroxyvitamin D3 in human osteoblast-like cells. J. Bone Miner. Res. (1996) 11:472–479.
  • THOMAS KA: Vascular endothelial growth factor, a potent and selective angiogenic agent. J. Biol. Chem. (1996) 271:603–606.
  • CRYSTAL RG: Transfer of genes to humans: early lessons and obstacles to success. Science (1995) 270:404–410.
  • •Exhaustive review of vectors for gene therapy.
  • EVANS CH, ROBBINS PD: Possible orthopaedic applica-tions of gene therapy. J. Bone Joint Surg. (1995) 77A:1103–1113.
  • DING L, LU S, BATCHU R, III RS, MUNSHI N: Bone marrowstromal cells as a vehicle for gene transfer. Gene Ther. (1999) 6:1611–1616.
  • NIYIBIZI C, BALTZER A, LATTERMANN C et al.: Potentialrole for gene therapy in the enhancement of fracture healing. Clin. Orthop. (1998) S355:5148–5153.
  • GERICH TG, KANG R, FU FH, ROBBINS PD, EVANS CH:Gene transfer to the rabbit patellar tendon: potential for genetic enhancement of tendon and ligament healing. Gene Ther. (1996) 3:1089–1093.
  • LIEBERMAN JR, DALUISKI A, STEVENSON S et al.: Theeffect of regional gene therapy with bone morphoge-netic protein-2 producing bone-marrow cells on the repair of segmental femoral defects in rats. J. Bone Joint Surg. (1999) 81A:905–917.
  • BALTZER AWA, LATTERMANN C, WHALEN JD, BRAUNSTEIN S, ROBBINS PD, EVANS CH: A gene therapy approach to accelerating bone healing: evaluation of gene expression in a New Zealand white rabbit model. Knee Surg. Sports Traumatol. Arthrosc. (1999) 7:197–202.
  • FANG J, ZHU Y-Y, SMILEY E et al. Stimulation of new bone formation by direct transfer of osteogenic plasmid genes. Proc. Natl. Acad. Sci. USA (1996) 93:5753–5758.
  • GOLDSTEIN SA, BONADIO J: Potential role for directgene transfer in the enhancement of fracture healing. Orthop. Rel. Res. (1998) 355S:S154–S162.
  • BODEN S, TITUS L, HAIR G et al.: Lumbar spine fusion bylocal gene therapy with cDNA encoding a novel osteoinductive protein (LMP-1). Spine (1998) 23:2486–2492.
  • LIU Y, HAIR G, TITUS L et al.: BMP-6 induces a novel UM protein involved in bone mineralization and osteocalcin secretion. J. Bone Min. Res. (1997) 12:S115.
  • BODEN SD, HAIR G, TITUS L et al: Glucocorticoid-induced differentiation of fetal rat calvarial osteoblasts is mediated by BMP-6. Endocrinology (1997) 138(7)2820–2828.
  • BALTZER AWA, LATTERMANN C, WHALEN JD et al.: Genetic enhancement of fracture repair: healing of an experimental segmental defect by adenoviral transfer of the BMP-2 gene. Gene Ther. (2000) 7:734–739.

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