152
Views
38
CrossRef citations to date
0
Altmetric
Review

Anti-adhesive strategies in the prevention of infectious disease at mucosal surfaces

&
Pages 1711-1721 | Published online: 24 Feb 2005

Bibliography

  • RELMAN D, TUOMANEN E, FALKOW S, GOLENBOCK DT, SAUKKONEN K, WRIGHT SD: Recognition of a bacterial adhesin by an integrin: macrophage CR3 (am132, CD11b/CD18) binds filamentous hemagglutinin of Bordetella pertussis. Cell (1990) 61:1375–1382.
  • OLSEN A, WICK MJ, MORGELIN M, BJORCK L: Curli, fibrous surface proteins of Escherichia coli, interact with major histocompatibility complex class I molecules. Infect. Immun. (1998) 66:944–949.
  • ZAIDI TS, FLEISZIG SM, PRESTON MJ, GOLDBERG JB, PIERGB: Lipopolysaccharide outer core is a ligand for corneal cell binding and ingestion of Pseudomonas aeruginosa. Invest. Ophthalmol. Vis. Sci. (1996) 37:976–986.
  • KANBE T, CUTLER JE: Evidence for adhesin activity inthe acid-stable moiety of the phosphomannoprotein cell wall complex of Candida albicans. Infect. Immun. (1994) 62:1662–1668.
  • ROBERTS JA, MARKLUND B, ILVER D et al.: TheGal(a1-4)Gal-specific tip adhesin of Escherichia coli P-fimbriae is needed for pyelonephritis to occur in the normal urinary tract. Proc. Natl. Acad. Sci. USA (1994) 91:11889–11893.
  • •Together with [6], these studies are good examples of those that demonstrate the importance of adhesion for pathology.
  • CONNELL H, AGACE W, KLEMM P, SCHEMBRI M, MARILD, SVANBORG C: Type 1 fimbrial expression enhances Escherichia coli virulence for the urinary tract. Proc. Natl. Acad. Sci. USA (1996) 93:9827–9832.
  • •See reference 5 for annotation.
  • GURUGE JL, FALK PG, LORENZ RG et al.: Epithelial alters the outcome of Helkobacter pylori infection. Proc. Nati Acad. Sci USA (1998)95:3925–3930.
  • ••Demonstrates the requirement for adhesion to producepathology using transgenic mice expressing Lewis b blood group antigen.
  • STEIN M, RAPPUOLI R, COVACCI A: Tyrosine phospho- of the Helkobacter pylori Cag antigen after cag-driven host cell translocation. Proc. Natl. Acad. Sci. USA (1997) 97:1263–1268.
  • •Provides the first step in a molecular explanation for pathology resulting from adhesion.
  • HAWKEY PM: Action against antibiotic resistance: no time to lose. Lancet (1998) 351:1298–1299.
  • IRVIN RT, BAUTISTA DL: Hope for the post-antibiotic era? Nature Biotechnoi (1999) 17:20.
  • LEHNER T, CALDWELL J, SMITH R: 'Deal passive immuni-zation by monoclonal antibodies against streptococcal antigen VII in the prevention of dental caries. Infect. Immun. (1985) 50:796–799.
  • ••Important study that demonstrates protection againstdisease in an animal model.
  • MA JK-C, HUNJAN M, SMITH R, LEHNER T: Specificity of antibodies in local passive immunization against Streptococcus mutans. Clin. Exp. Immunol. (1989) 77:331–337.
  • ••Demonstrates long-term protection against infection inhumans.
  • MA JK-C, HUNJAN M, SMITH R, KELLY C, LEHNER T: An investigation into the mechanisms of protection by local passive immunization with monoclonal antibodies against Streptococcus mutans. Infect. Immun. (1990) 58:3407–3414.
  • MA JK-C, HIKMAT BY, WYCOFF K et al.: Characterization of a recombinant plant monoclonal secretory antibody and preventive immunotherapy in humans. Nature Med. (1998) 4:601–606.
  • ••First use of a plant-derived SIgA antibody in human therapy.
  • BOOTH V, ASHLEY FP, LEHNER T: Passive immunization monoclonal antibodies against Porphyromonas gingivalisin patients with periodontitis. Infect. Immun. (1996) 64:422–427.
  • •Further example of protection against infection in humans.
  • DE BERNARDIS F, BOCCANERA M, ADRIANI D, SPREGHINI E, SANTONI G, CASSONE A: Protective role of antimannan and anti-aspartyl proteinase antibodies in an experimental model of Candida albicans vaginitis in rats. Infect. Immun. (1997) 65:3399–3405.
  • HAN Y, MORRISON RP, CUTLER JE: A vaccine and antibodies that enhance mouse resistance to Candida albicans vaginal infection. Infect. Immun. (1998) 66:5771–5776.
  • •Demonstrates that intravaginal administration of antibody can protect against candidiasis.
  • HAN Y, RIESSELMAN MH, CUTLER JE: Protection against can didiasis by an immunoglobulin G3 (IgG3) monoclonal antibody specific for the same ann o trio se as an IgM protective antibody. Infect. Immun. (2000) 68:1649–1654.
  • WATTS HJ, CHEAH FSH, HUBE B, SANGLARD D, GOW NAR: Altered adherence in strains of Candida albicans harbouring null mutations in secreted aspartic proteinase genes. FEMS Microbiol. Lett. (1998) 159:129–135.
  • LANGERMANN S, PALASZYNSKI S, BARNHART M et al.: of mucosal Escherichia coli infection by FimH-Adhesin-based systemic vaccination. Science (1997) 276:607–611.
  • ••Clear demonstration of the effectiveness of anti-adhesinantibody (anti-FimH) to clear infection at a site that is not normally colonised.
  • LANGERMANN S, MOLBY R, BURLEIN JE et al.: Vaccina- with FimH adhesin protects cynomolgus monkeys from colonization and infection by Escherichia coli. J. Infect. Dis. (2000) 81:774–778.
  • •Further demonstration of the effectiveness of antibodies in a non-human primate model.
  • KELLY CG, TODRYK S, KENDAL HL, MUNRO GH, LEHNERT: T-cell adhesion and B-cell epitopes of the cell surface Streptococcus mutans protein antigen I/II. Infect. Immun. (1995) 63:3649–3658.
  • KELLY CG, YOUNSON JS, HIKMAT BY et al: A syntheticpeptide adhesion epitope as a novel antimicrobial agent. Nature Biotechnol. (1999) 17:42–47.
  • •Describes protection against infection in humans following application of a synthetic peptide adhesin analogue.
  • IJAZ MK, NUR-E-KAMAL MSA, DAR FK et al.: Inhibition of infection in vitro and in vivo by a synthetic peptide from VP4. Vaccine (1998) 16:916–920.
  • •Demonstrates that an effective dose of synthetic peptide can be delivered to the intestine.
  • ZAIDI TS, PRESTON MJ, PIER GB: Inhibition of bacterialadherence to host tissue does not markedly affect disease in the murine model of Pseudomonas aerugi-nosa corneal infection. Infect. Immun. (1997) 65:1370–1376.
  • LEININGER E, ROBERTS M, KENIMER JG et al: Per tactin,an Ar g-Gly -Asp -containing Bordetella pertussis surface protein that promotes adherence of mammalian cells. Proc. Natl. Acad. Sci. USA (1991) 88:345–349.
  • TALAY SR, VALENTIN-WEIGAND P, JERLSTROM PG, TIMMIS KN, CHHATWAL GS: Fibr on ectin-binding protein of Streptococcus pyogenes: sequence of the binding domain involved in adherence of streptococci to epithelial cells. Infect. Immun. (1992) 60:3837–3844.
  • LEE KK, WONG WY, SHETH HB, HODGES RS, PARANCHYCH W, IRVIN RT: Use of synthetic peptides in characterization of microbial adhesins. Methods Enzymol. (1995) 253:115–131.
  • PUTNEY SD, BURKE PA: Improving protein therapeu-tics with sustained-release formulations. Nature Biotechnol. (1998) 16:153–157.
  • SLOAN-LANCASTER J, ALLEN PM: Altered peptideligand-induced partial T cell activation: molecular mechanisms and role in T cell biology. Ann. Rev. Immunol. (1996) 14:1–27.
  • ARONSON M, MEDALIA 0, SCHORI L, MIRELMAN D, SHARON N, OFEK I: Prevention of colonisation of the urinary tract of mice with Escherichia coliby blocking of bacterial adherence with methyl a-D- mannopyra-noside. J. Infect. Dis. (1979) 1 3 9:329–332.
  • •Early demonstration of prevention of infection with carbohydrate receptor analogues.
  • NEWBURG DS: Do the binding properties of oligosac- in milk protect human infants from gastroin-testinal bacteria? Nutr. (1997) 127:980S–984S.
  • KARLSSON K-A: Meaning and therapeutic potential of microbial recognition of host glycoconjugates. Mot. Microbiol. (1998) 29:1–11.
  • ZOPF D, ROTH S: Oligosaccharide anti-infective agents. Lancet (1996) 347:1017–1020.
  • •This, together with [35], is a good review of the use of oligosaccharide receptor analogues.
  • GREVE JM, DAVIS G, MEYER AM et al: The major human receptor is ICAM-1. Cell (1989) 56:839–847.
  • •See reference 34 for annotation.
  • STAUNTON DE, MERLUZZI VJ, ROTHLEIN R, BARTON R,MARLIN SD, SPRINGER TA: A cell adhesion molecule, ICAM-1, is the major surface receptor for rhinoviruses. Cell (1989) 56:849–853.
  • MARLIN SD, STAUNTON DE, SPRINGER TA, STRATOWA C,SOMMERGRUBER W, MERLUZZI VJ: A soluble form of intercellular adhesion molecule-1 inhibits rhinovirus infection. Nature (1990) 344:70–72.
  • HUGUENEL HD, COHN D, DOCKUM DP et al: Prevention of rhinovirus infection in chimpanzees by soluble intercellular adhesion molecule-1. Am. J Respir. Crit. Care Med. (1997) 155:1206–1210.
  • TURNER RB, WECKER MT, POHL G et al.: Efficacy of tremacamra, a soluble intercellular adhesion molecule 1, for experimental rhinovirus infection. JAMA (1999) 281: 1797-1804.
  • ••Human clinical trial demonstrating reduction in diseaseseverity (experimental infection with rhinovirus) due to treatment with a receptor analogue, soluble ICAM-1.
  • BARTHELSON R, MOBASSERI A, ZOPF D, SIMON P: Adherence of Streptococcus pneumoniae to respira-tory epithelial cells is inhibited by sialylated oligosac-charides. Infect. Iminun. (1998) 66:1439–1444.
  • IDANPÄÄN-HEIKKILA I, SIMON P, ZOPF D et al: Oligo sac-charides interfere with the establishment and progression of experimental pneumococcal pneumonia. J. Infect. Dis. (1997) 176:704–712.
  • •Shows in vivo protection against disease in an animal model with defined oligosaccharide receptor analogues.
  • BRYAN R, FELDMAN M, JAWETZ SC et al.: The effects of aerosolised dextran in a mouse model of Pseudo-monas aeruginosa pulmonary infection. J. Infect. Dis. (1999) 179:1449–1458.
  • MOURICOUT M, PETIT JM, CARIAS JR, JULIEN R: Glycoprotein glycans that inhibit adhesion of Escheri-chia coli mediated by K99 fimbriae: treatment of experimental colibacillosis. Infect. Immun. (1990) 58:98–106.
  • EVANS DG, KARJALAINEN TK, EVANS DJ, GRAHAM DY,LEE CH: Cloning, nucleotide sequence and expression of a gene encoding an adhesin subunit protein of pylori. J. Bacteriol (1993) 175:674–683.
  • MYSORE JV, WIGGINTON T, SIMON PM, ZOPF D, HEMAN-ACKAH LM, DUBOIS A: Treatment of Helko-barter pylori infection in rhesus monkeys using a antiadhesion compound. Gastroenterology (1999) 117:1316–1325.
  • •Partially successful attempt to treat established infection in an animal model.
  • COURTNEY HS, DALE JB, HASTY DL: Differential effects of the streptococcal fibronectin-binding protein, FBP54, on adhesion of group A streptococci to human buccal cells and Hep-2 tissue culture cells. Infect. Immun. (1996) 64:2415–2419.
  • VAN DER FLIER M, CHHUN N, WIZEMANN TM, MIN J, MCCARTHY JB, TUOMANEN El: Adherence of Strepto-coccus pneumoniae to immobilized fibronectin. Infect. Immun. (1995) 63:4317–4322.
  • WINTER G: Synthetic human antibodies and a strategy for protein engineering. FEBS Lett. (1998) 430:92–94.
  • KELLY CG, YOUNSON JS, HIKMAT BY et al.: A synthetic peptide adhesion epitope as a novel antimicrobial agent. Nature Biotechnol. (1999) 17:42–47.

Websites

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.