380
Views
11
CrossRef citations to date
0
Altmetric
Reviews

Are biological targets the final goal for rheumatoid arthritis therapy?

&
Pages 1611-1622 | Published online: 06 Sep 2012

Bibliography

  • Caporali R, Caprioli M, Pallavicini FB, DMARDs and infections in rheumatoid arthritis. Autoimmun Rev 2008;8:139-43
  • Curtis JR, Patkar N, Xie A, Risk of serious bacterial infections among rheumatoid arthritis patients exposed to tumor necrosis factor alpha antagonists. Arthritis Rheum 2007;56:1125-33
  • Rai P, Mallidi S, Zheng X, Development and applications of photo – triggered theranostic agents. Adv Drug Deliv Rev 2010;52:1094-124
  • Hogset A, Prasmickaite L, Selbo PK, Photochemical internalisation in drug and gene delivery. Adv Drug Deliv Rev 2004;56:95-115
  • Hou WS, Li Z, Buttner FH, Cleavage site specificity of cathepsin K toward cartilage proteoglycans and protease complex formation. Biol Chem 2003;384:891-7
  • Desai N, Yang SA, Dykes D, Increased antitumor activity, intratumor paclitaxel concentrations, and endothelial cell transport of cremophor-free, albumin-bound paclitaxel, ABI-007, compared with cremophor-based paclitaxel. Clin Cancer Res 2006;12:1317-24
  • Amrutkar RD. DMARD'S and biological agents: the second line treatment for rheumatoid arthritis. IJPRD 2010;2:138-46
  • Kooloos WM, Jong D, Huizinga TWJ, Potential role of pharmacogenetics in anti – TNF treatment of rheumatoid arthritis and crohn's disease. Drug Discov Today 2007;12:125-31
  • Scott D L. Smith CK.What are the consequences of early rheumatoid arthritis for the individual? J Clin Rheumatol 2005;19:117-36
  • Chen CJ, Lai HM. Biologics in the treatment of rheumatoid arthritis: recent advances. Fofmosan J Rheumatol 2008;22:12-24
  • Taylor PC, Mehta P, Tull T. An etiopathology of rheumatoid arthritis. Rheumatoid Arthritis 2009;38:164-9
  • Mody GM, Hammond MG, Naidoo PD. Challenges in the management of rheumatoid arthritis in developing countries. Best Pract Res Cl Rh 2008;22:621-41
  • Yocum DET. Cells: pathogenic Cells and Therapeutics in Rheumatoid Arthritis. Semin Arthritis Rheum 1999;29:27-35
  • Combe B. Early rheumatoid arthritis: strategies for prevention and management. Best Pract Res Cl Rh 2007;21:27-42
  • Weinblatt ME, Fleischmann RM, Fox RI, A trial of etanercept, a recombinant tumor necrosis factor receptor: fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate. N Engl J Med 1999;340:253-9
  • Pincus T, Kavanaugh A, Sokka T. Benefit/risk of therapies for rheumatoid arthritis: underestimation of the ‘side effects' or risks of RA leads to underestimation of the benefit/risk of therapies. Clin Exp Rheumatol 2004;22:2-11
  • Lee DM, Weinblatt ME. Rheumatoid arthritis. Lancet 2001;35:903-11
  • Manghani M, Tymms K, Barrett C. Recommendations for the use of biologic agents for the treatment of rheumatic diseases. ARA Oral abstracts published in Internal Journal Medicine 2011;41:1-12
  • Kavanaugh A, Lee SJ. Adverse reactions to biologic agents: focus on autoimmune disease therapies. Best Pract Res Cl Rh 2005;116:900-5
  • Khraishi M, Russell A, Olszynski WP, Safety profile of abatacept in Rheumatoid Arthritis: a Review. Clin Ther 2010;32:1855-70
  • Tang B, Rahman M, Waters HC, Treatment persistence with adalimumab, etanercept, or infliximab in combination with methotrexate and the effects on health care costs in patients with rheumatoid arthritis. Clin Ther 2008;30:1375-84
  • Broeder AA, Jong E, Franssen MJA, Observational study on efficacy, safety, and drug survival of anakinra in rheumatoid arthritis patients in clinical practice. Ann Rheum Dis 2006;65:760-2
  • Berthelot JM, Varin S, Cormier G, 25 mg etanercept once weekly in rheumatoid arthritis and spondylarthropathy. Joint Bone Spine 2007;74:144-7
  • Atzeni F, Doria A, Maurizio T, Puttini PS. What is the role of rituximab in the treatment of rheumatoid arthritis? Autoimmun Rev 2007;6:553-8
  • Oldfield V, Dhillon S, Plosker GL. Tocilizumab: a review of its use in the management of rheumatoid arthritis. Drugs 2009;69:609-32
  • Romas E, Sims NA, Hards DK, Osteoprotegerin reduces osteoclast numbers and prevents bone erosion in collagen induced arthritis. Am J Pathol 2002;161:1419-27
  • Rheumatology therapeutics: drugs and biologics. FDA public health advisory, Washington, DC: FDA/Center for Drug Evaluation and Research, 2010. Available from http://www.fda.gov/Drugs/DrugSafety/InformationbyDrugClass/ucm105782.htm [Last] [accessed 9 january 2010]
  • Rosenblum H, Amital H. Anti – TNF therapy: safety aspects of taking the risk. Autoimmun Rev 2011;10:563-8
  • Kavanaugh A, Lee SJ. Adverse reactions to biologic agents: focus on autoimmune disease therapies. Best Pract Res Cl Rh 2005;116:900-5
  • Maini RN, Breedveld F, Furst D, Infliximab (chimeric antitumor necrosis factor a monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. Lancet 1999;354:1932-9
  • Feldman M, Maini RN. Anti-TNFalpha therapy of rheumatoid arthritis: what have we learned? Ann Rev Immunol 2001;19:163-96
  • Adalimumab product information – Licensing action 12/31/2012. DC: FDA/Center for Drug Evaluation and Research, 2009. Available from: http://www.fda.gov/ Drugs /DevelopmentApprovalProcess/HowDrugsareDevelopedandApproved/ApprovalApplications/TherapeuticBiologicApplications/ucm080610.htm [Last accessed 29 October 2009]
  • Cunnane G, Doran M, Bresnihan B. Infections and biological therapy in rheumatoid arthritis. Best Pract Res Cl Rh 2003;17:345-63
  • Boyce EG, Halilovic J, Oby SU. Golimumab: Review of the efficacy and tolerability of a recently approved tumor necrosis factor-alpha inhibitor. Clin Therap 2010;32:2010
  • Taylor PC. Antibody therapy for rheumatoid arthritis. Curr Opin Pharmacol 2003;3:323-8
  • Valesini G, Iannuccelli C, Marocchi E, Biological and clinical effects of anti – TNF a treatment. Autoimmun Rev 2007;7:35-41
  • Breedveld FC. Future treatment. Bailliere Clin Rheumatol 1997;11:83-97
  • Simon MB, Swift B. What next for rheumatoid arthritis therapy? Current Opinion in Pharmacology. Curr Opin Pharmacol 2004;4:276-80
  • Wong M, Ziring D, Kim S, TNFalpha blockade in human diseases: Mechanism and future directions. Clin Immunol 2008;126:121-36
  • Wada M, Kawahito Y, Kimura S, siRNA targeting PLK-1 induces apoptosis of synoviocytes in rheumatoid arthritis. Biochem Biophys Res Commun 2009;11:353-9
  • Muller-Ladner U, Kriegsmann J, Franklin BN, Synovial fibroblasts of patients with rheumatoid arthritis attaches to and invades normal human cartilage when engrafted into SCID mice. Am J Pathol 1996;149:1607-15
  • Tarner IH, Lander UM, Fathman CG. Developing the concept of adoptive cellular gene therapy of rheumatoid arthritis. Autoimmun Rev 2006;5:148-52
  • Kratz F. Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles. J Control Release 2008;132:171-83
  • Wunder A, Ladner MU, Stelzer EH, Albumin-based drug delivery as novel therapeutic approach for rheumatoid arthritis. J Immunol 2003;9:4793-801
  • Peters T. Serum albumin. Adv Protein Chem 1985;3:161-245
  • Fasano M, Curry S, Terreno E, The extraordinary ligand binding properties of human serum albumin. IUBMB Life 2005;57:787-96
  • Carter DC, Twigg PD, Miller T Y. Three-dimensional structure of human serum albumin. Science 1989;244:1195-8
  • Yang A, Tao C, De T, Increased antitumor activity,intratumor paclitaxel concentrations, and endothelial cell transport of cremophor-free, albumin-bound paclitaxel, ABI-007, compared with cremophor-based paclitaxel. Clin Cancer Res 2006;12:1317-24
  • Elsadek B, Kratz F. Impact of albumin on drug delivery — New applications on the horizon. J Controlled Release 2012;157:4-28
  • Koo OM, Rubinstein I, Onyuksel H. Role of nanotechnology in targeted drug delivery and imaging: a concise review. Nanomed-Nanotechnol 2005;1:193-212
  • Yuan F, Quan LD, Cui L, Development of macromolecular prodrug for rheumatoid arthritis. Adv Drug Deliv Rev 2012;1:1-15
  • Elsadek B, Kratz F. Impact of albumin on drug delivery – New applications on the horizon. J Control Release 2012;157:4-28
  • Delgado M, Gomariz RP, Ganea D. Vasoactive intestinal peptide and pituitary adenylate cyclase activating polypeptide prevent inducible nitric oxide synthase transcription in macrophages by inhibiting NF-B and IFN regulatory factor 1 activation. J Immunol 1999;162:4685-96
  • Delgado M, Abad C, Leceta J, Vasoactive intestinal peptide prevents experimental arthritis by downregulating both autoimmune and inflammatory components of the disease. Nat Med 2001;7:563-8
  • Juarranz Y, Abad C, Martinez C, Protective effect of vasoactive intestinal peptide on bone destruction in the collagen – induced arthritis model of rheumatoid arthritis. Arthritis Res Ther 2005;7:1034-44
  • Rey EG, Delgado M. Vasoactive intestinal peptide inhibits cycloxygenase – 2 expression in activated macrophages, microglia, and dendritic cells. Brain Behav Immun 2008;22:35-41
  • Kim KS, Park SJ, Yang JA, Injectable hyaluronic acid–tyramine hydrogels for the treatment of rheumatoid arthritis. Acta Biomater 2011;7:666-74
  • Zhao X, Alexander C, Fraser J. Intrarticular delivery: A fast growing approach. US20077226972; 2007
  • Callegaro L, Renier D. Sulphated hyaluronic acid for treating osteoarthiritis. US20090197807; 2010
  • Betre H, Liu W, Zalutsky MR, A thermally responsive biopolymer for intra-articular drug delivery. J Controlled Release 2006;115:175-82
  • Tomlinson E. Theory and practice of site – specific drug delivery. Adv Drug Deliv Rev 1987;1:87-198
  • Hoshi K, Mizushima Y, Shiokawa Y, Double – blind study with liposteroid in rheumatoid arthritis. Drugs Exp Clin Res 1985;11:621-6
  • Richards P J, Williams B D, Williams A S. Suppression of chronic streptococcal cell wall – induced arthritis in lewis rats by liposomal clodronate. Rheumatology 2001;40:978-87
  • Chandrasekar D, Sistla R, Ahmad FJ, The development of folate-PAMAM dendrimer conjugates for targeted delivery of anti-arthritic drugs and their pharmacokinetics and biodistribution in arthritic rats. Biomaterials 2007;28:504-12
  • Turk MJ, Breur GJ, Widmer WR, Folate-targeted imaging of activated macrophages in rats with adjuvant-induced arthritis. Arthritis Rheum 2002;46:1947-55
  • Paulos C M, Turk M J, Breur G J, Folate receptor – mediated targeting of therapeutic and imaging agents to activated macrophages in rheumatoid arthritis. Adv Drug Deliver Rev 2004;56:1205-17
  • Fredholm BB. Adenosine, an endogenous distress signal, modulates tissue damage And repair. Cell Death Differ 2007;14:1315-23
  • Varani K, Padovan M, Govoni M, The role of adenosine receptors in rheumatoid arthritis. Autoimmun Rev 2010;10:61-4
  • Ochaion A, Yehuda SB, Cohen S, The A3 adenosine receptor agonist CF502 inhibits the PI3K,PKB/Akt and NF-kB signalling pathway in synoviocytes from rheumatoid arthritis patients and in adjuvant-induced arthritis rats. Biochem Pharmacol 2008;76:482-94
  • Morovic-Vergles J, Culo MI, Gamulin S, Culo F. Cyclic adenosine 5′-monophosphate in synovial fluid of rheumatoid arthritis and osteoarthritis patients. Rheum Int 2008;29:167-71
  • Dodds RA, Drake FH, Holmes S, Human osteoclasts cathepsin K is processed intracellularly prior to attachment and bone resorption.J Bone Miner. 2001;16:478-86
  • Hou WS, Li W, Keyszer G, Comparison of cathepsins K and S expression within the rheumatoid and osteoarthritic synovium. Arthritis Rheum 2002;46:663-74
  • Skoumal M, Haberhauer G, Kolarz G, Serum cathepsin K levels of patients with longstanding rheumatoid arthritis: correlation with radiological destruction. Arthritis Res Ther 2004;7:65-70
  • Yasuda Y, Kaleta J, Bromme D. The role of cathepsins in osteoporosis and arthritis: rationale for the design of new therapeutics. Adv Drug Deliv 2005;57:973-93
  • Hayami T, Zhuo Y, Welsolowski GA, Inhibition of cathepsin K reduces cartilage degeneration in the anterior cruciate ligament transection rabbit and murine models of osteoarthritis. Bone 2012;50:1250-9
  • Liu C. Progranulin: A promising therapeutic target for rheumatoid arthritis. FEBS Lett 2011;585(23):3675-80
  • Tang W, Lu Y, Tian Q-Y, The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice. Science 2011;332:478-84
  • Adigbi D K, MacRobert A J. Photochemical internalisation: the journey from basic scientific concept to the threshold of clinical application. Curr Opin Pharmacol 2012;12:1-5
  • Nyman ES, Hynninen PH. Research advances in the use of tetrapyrrolic photosensitizers for photodynamic therapy. J Photochem Photobiol 2004;73:1-28
  • Schutz C, Schmitt F, Lagopoulos L, Efficient delivery of photosensitizers for rheumatoid arthritis(RA) treatment by photodynamic therapy (PDT). Eur Cell Mater 2008;16:53
  • Gabriel D, Busso N, Lange N, Thrombinsensitive photodynamic agents: a novel strategy for selective synovectomy in rheumatoid arthritis. J Control Release 2009;138:225-34
  • Liu TWB, Chen J, Burgess L, Multimodal bacteriochlorophyll theranostic agent. Thno 2011;1:354-62

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.