172
Views
63
CrossRef citations to date
0
Altmetric
Review

Smart polymeric carriers for enhanced intracellular delivery of therapeutic macromolecules

, &
Pages 23-32 | Published online: 20 Apr 2005

Bibliography

  • SKEHEL JJ, WILEY DC: Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin. Annu. Rev. Biochem. (2000) 69:531–569.
  • WILEY DC, SKEHEL JJ: The structure and function of the hemagglutinin membrane glycoprotein of influenza virus. Annu. Rev. Biochem. (1987) 56:365–394.
  • HUGHSON FM: Structural characterization of viral fusion proteins. Curr. Biol. (1995) 5:265–274.
  • REN J, SHARPE JC, COLLIER RJ, LONDON E: Membrane translocation of charged residues at the tips of hydrophobic helices in the T domain of diphtheria toxin. Biochemistry (1999) 38:976–984.
  • GRIMM D, KAY MA: From virus evolution to vector revolution: use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy. Curr. Gene Ther. (2003) 3:281–304.
  • WAGNER E, PLANK C, ZATLOUKAL K, COTTON M, BIRNSTIEL ML: Influenza virus hemagglutinin HA-2 N-terminal fitsogenic peptides augment gene transfer by transferring-polylysine-DNA complexes: toward a synthetic virus-like gene transfer vehicle. Proc. Nail. Acad. Sci. USA (1992) 89:7934–7938.
  • PLANK C, OBERHAUSER B, MECHTLER K, KOCH C, WAGNER E: The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems. J. Biol. Chem. (1994) 269:12918–12924.
  • TOLSTIKOV VV COLE R, FANG H, PINCUS SH: Influence of endosome-destabilizing peptides on efficacy of anti-HIV immunotoxins. Bioconjug Chem. (1997) 8:38–43.
  • SUBBARAO NK, PARENTE RA, SZOKA FC JR, NADASDI L, PONGRACZ K: pH-dependent bilayer destabilization by an amphipathic peptide. Biochemistry (1987) 26:2964–2972.
  • PARENTE RA, NIR S, SZOKA FC JR: pH-dependent fusion of phosphatidylcholine small vesicles. J. Biol Chem. (1988) 263:4724–4730.
  • LUNDBERG M, JOHANSSON M: Positively charged DNA-binding proteins cause apparent cell membrane translocation. Biochem. Biophys. Res. Commun. (2002) 291(2):367–371.
  • CONSOLES, MARTY C, GARCIA-ECHEVERRIA C, SCHWENDENER R, BALLMER-HOFER K: Antennapedia and HIV transactivator of transcription (TAT) 'protein transduction domains' promote endocytosis of high molecular weight cargo upon binding to cell surface glycosaminoglycans. j Biol Chem. (2003) 278(37):35109–35114.
  • VIVES E, BRODIN P, LEBLEU B: A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J. Biol Chem. (1997) 272(25):16010–16017.
  • SCHWARZE SR, HRUSKA K, DOWDY SF: Protein transduction: unrestricted delivery into all cells? Trends Cell Biol. (2000) 10(7):290–295.
  • SCHWARZE SR, HO A, VOCERO-AKBANI A, DOWDY SF: In vivo protein transduction: delivery of a biologically active protein into the mouse. Science (1999) 285(5433):1569–1572.
  • LEWIN M, CARLESSO N, TUNG CH et al.: Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells. Nat. Biotechnol. (2000) 18(4):410–414.
  • ASTRIAB-FISHER A, SERGUEEV D, FISHER M, SHAW BR, JULIANO RL: Conjugates of antisense oligonucleotides with the Tat and Antennapedia cell-penetrating peptides: Effects on cellular uptake, binding to target sequences, and biologic actions. Pharm. Res. (2002) 19(6):744–754.
  • TAKAKURA Y, HASHIDA M: Macromolecular carrier systems for targeting drug delivery: pharmacokinetic considerations on biodistribution. Pharm. Res. (1996) 13:820–831.
  • NOGUCHI Y, WU J, DUNCAN R et al: Early phase tumor accumulation of macromolecules: a great difference between the tumor versus normal tissue in their clearance rate. Jpn. J. Cancer Res. (1998) 89:307–314.
  • THOMAS JL, TIRRELL DA: Polyelectrolyte-sensitized phospholipid vesicles. Acc. Chem. Res. (1992) 25:336–342.
  • MURTHY N, ROBICHAUD JR, TIRRELL DT, STAYTON PS, HOFFMAN AS: The design and synthesis of polymers for eukaryotic membrane disruption. J. Control. Release (1999) 61:137–143.
  • MURTHY N, CHANG I, STAYTON PS, HOFFMAN AS: pH-sensitive hemolysis by random copolymers of alkyl acrylates and acrylic acid. Macromolec. Symp. (2001) 172:49–55.
  • CHEUNG CY, MURTHY N, STAYTON PS, HOFFMAN AS: A pH-sensitive polymer that enhances cationic lipid-mediated gene transfer. Bioconjug Chem. (2001) 12:906–910.
  • CHEUNG CY, STAYTON PS, HOFFMAN AS: Poly(propylacrylic acid)-mediated reduction in serum component inactivation of cationic lipoplexes. Submitted (2004).
  • KYRIAKIDES TR, CHEUNG CY, MURTHY N et al.: pH-sensitive polymers that enhance intracellular drug delivery in vivo. J. Control. Release (2002) 78:295–303.
  • KYRIAKIDES TR, ZHU YN, SMITH LT et al.: Mice that lack thrombospondin 2 display connective tissue abnormalities that are associated with disordered collagen fibrillogenesis, an increased vascular density, and a bleeding diathesis. J. Cell Biol. (1998) 140:419–430.
  • KYRIAKIDES TR, HARTZEL T, HUYEN G, BORNSTEIN P: Modulation of angiogenesis and matrix remodeling by localized, matrix-mediated, antisense gene delivery. Mo/. Ther. (2001) 3:842–849.
  • KYRIAKIDES TR, TAM JW, BORNSTEIN P: Accelerated wound healing in mice with a disruption of the thrombosponding 2 gene. J. Invest. DermatoL (1999) 113:782–787.
  • PRESS OW, HANSEN JA, FARR A. MARTIN PJ: Endocytosis and degradation of murine anti-human CD3 monoclonal antibodies by normal and malignant T-lymphocytes. Cancer Res. (1988) 48:2249–2257.
  • WAWRZYNCZAK EJ: Systemic immunotoxin therapy of cancer: advances and prospects. Br. J. Cancer (1991) 64:624–630.
  • LACKEY CA, MURTHY N, PRESS OW et al.: Hemolytic activity of pH-responsive polymer-streptavidin bioconjugates. Bioconjug. Chem. (1999) 10:401–405.
  • LACKEY CA, PRESS OW, HOFFMAN AS, STAYTON PS: A biomimetic pH-responsive polymer directs endosomal release and intracellular delivery of an endocytosed antibody complex. Bioconjug. Chem. (2002) 13:996–1001.
  • GEISSLER F, ANDERSON SK, PRESS O: Intracellular catabolism of radiolabeled anti-CD3 antibodies by leukemic T cells. Cell. Immunol (1991) 137:96–110.
  • SCHAFFAR L, DALLANEGRA A, BREITTMAYER JP, CARRELS, FEHLMANN M: Monoclonal antibody internalization and degradation during modulation of the CD3/T-cell receptor complex. Cell. Immunol (1988) 116:52–59.
  • BULMUS V WOODWARD M, LIN L et al.: A new pH-responsive and glutathione-reactive, endosomal membrane-disruptive polymeric carrier for intracellular delivery of biomolecular drugs. J. Control Release (2003) 93:105–120.
  • EL-SAYED MEH, HOFFMAN AS, STAYTON PS: Rational design of composition and activity correlations for pH-sensitive and glutathione-reactive polymer therapeutics. J. Control. Release (2005) 101(1-3):47–58.
  • MURTHY N, CAMPBELL J, FAUSTO N,HOFFMAN AS, STAYTON PS: Bioinspired polymeric carriers that enhance intracellular delivery of biomolecular therapeutics. Bioconjug. Chem. (2003) 14:412–419.
  • MURTHY N, CAMPBELL J, FAUSTO N,HOFFMAN AS, STAYTON PS: Design and synthesis of pH-responsive polymeric carriers that target uptake and enhance the intracellular delivery of oligonucleotides. J. Control. Release (2003) 89(3):365–374.
  • TYCKO B, KEITH CH, MAXFIELD FR: Rapid acidification of endocytic vesicles containing asialoglycoprotein in cells of a human hepatoma cell line. J. Cell Biol. (1983) 94:3191-3197. Affiliation Mohamed EH El-Sayed, Allan S Hoffman & Patrick S Stayton PhDl lAuthor for correspondence University of Washington, Department of Bioengineering, Box 351721, Seattle, WA 98195, USA Tel: +1 206 685 8148; Fax: +1 206 685 8526; E-mail: staytonOu.washington.edu

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.