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Drug Evaluation

Infliximab for the treatment of ankylosing spondylitis

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Pages 1095-1109 | Published online: 24 Nov 2005

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  • •This article can be used as a guidance for the conduct of clinical trials in AS.
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  • •The clinical efficacy of infliximab treatment of active AS is sustained over a period of 3 years. This is of note as no concomitant MTX or other immunosuppressants were given.
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  • ••First study showing that infliximab notonly improves clinical signs and symptoms, but also leads to a significant decrease of active inflammatory lesions in the spine as detectable by MRI.
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