158
Views
19
CrossRef citations to date
0
Altmetric
Drug Evaluation

Heat-shock protein–peptide complex-96 for the treatment of cancer

, DO
Pages 1267-1273 | Published online: 14 Aug 2007

Bibliography

  • PEGGS KS, QUEZADA SA, KORMAN AJ, ALLISON JP: Principles and use of anti-CTLA4 antibody in human cancer immunotherapy. Curr. Opin. Immunol. (2006) 18:206-213.
  • RITOSSA FA: New puffing pattern induced by temperature shock and DNP in Drosophilia. Experientia (1962) 18:571-573.
  • SRIVASTAVA PK: Immunotherapy for human cancer using heat shock protein–peptide complexes. Curr. Oncol. Rep. (2005) 7:104-108.
  • ZHU X, ZHAO X, BURKHOLDER WF et al.: Structural analysis of substrate binding by the molecular chaperone DnaK. Science (1996) 272:1606-1614.
  • MACARY PA, JAVID B, FLOTO RA et al.: HSP70 peptide binding mutants separate antigen delivery from dendritic cell stimulation. Immunity (2004) 20:95-106.
  • LINDEROTH NA, POPOWICZ A, SASTRY S: Identification of the peptide-binding site in the heat shock chaperone/tumor rejection antigen GP96 (Grp94). J. Biol. Chem. (2000) 272:5472-5477.
  • BAKER-LEPAIN JC, SAARZOTTI M, FIELDS TA, LI CY, NICCHITTA CV: GRP94 (GP96) and GRP94 N-terminal geldanamycin binding domain elicit tissue nonrestricted tumor suppression. J. Exp. Med. (2002) 196:1447-1459.
  • GIDALEVITZ T, BISWAS C, DING H et al.: Identification of the N-terminal peptide binding site of glucose-regulated protein 94. J. Biol. Chem. (2004) 279:16543-16552.
  • GOETZ MP, TOFT DO, AMES MM, ERLICHMAN C: The HSP90 chaperone complex as a novel target for cancer therapy. Ann. Oncol. (2003) 14:1169-1176.
  • ISHII T, UDONO H, YAMANO T et al.: Isolation of MHC class I-restricted tumor antigen peptide and its precursors associated with heat shock proteins HSP70, HSP90, and GP96. J. Immunol. (1999) 162:1303-1309.
  • SPONAAS AM, ZUEGEL U, WEBER S et al.: Immunization with GP96 from Listeria monocytogenes-infected mice is due to N-formylated listerial peptides. J. Immunol. (2001) 167:6480-6486.
  • MENG SD, SONG J, RAO Z et al.: Three-step purification of GP96 from human liver tumor tissues suitable for isolation of GP96-bound peptides. J. Immunol. Methods (2002) 264:29-35.
  • GROSSMANN ME, MADDEN BJ, GAO F et al.: Proteomics shows Hsp70 does not bind peptide sequences indiscriminately in vivo. Exp. Cell Res. (2004) 297:108-117.
  • DEMINE R, WALDEN P: Testing the role of GP96 as peptide chaperone in antigen processing. J. Biol. Chem. (2005) 280:17573-17578.
  • SRIVASTAVA P: Interaction of heat shock proteins with peptides and antigen presenting cells: chaperoning of the innate and adaptive immune responses. Annu. Rev. Immunol. (2002) 20:395-425.
  • PRZEPIORKA D, SRIVASTAVA PK: Heat shock protein–peptide complexes as immunotherapy for human cancer. Mol. Med. Today (1998) 4:478-484.
  • SRIVASTAVA PK, AMATO RJ: Heat shock proteins: the “Swiss Army Knife” vaccines against cancers and infectious agents. Vaccine (2001) 19:2590-2597.
  • SRIVASTAVA P: Roles of heat shock proteins in innate and adaptive immunity. Nat. Rev. Immunol. (2002) 2:185-194.
  • BINDER RJ, HAN DK, SRIVASTAVA PK: CD91: a receptor for heat shock protein GP96. Nat. Immunol. (2000) 1:151-155.
  • BASU S, BINDER RJ, RAMALINGAM T, SRIVASTAVA PK: CD91 is a common receptor for heat shock proteins GP96, HSP90, HSP70, and calreticulin. Immunity (2001) 14:303-313.
  • BANERJEE PP, VINAY DS, MATHEW A et al.: Evidence that glycoprotein 96 (B2), a stress protein, functions as a Th2-specific costimulatory molecule. J. Immunol. (2002) 169:3507-3518.
  • BINDER RJ, SRIVASTAVA PK: Essential role of CD91 in re-presentation of GP96-chaperoned peptides. Proc. Natl. Acad. Sci. USA (2004) 101:6128-6133.
  • PARK JE, FACCIPONTE J, CHEN X et al.: Chaperoning function of stress protein grp170, a member of the HSP70 superfamily, is responsible for its immunoadjuvant activity. Cancer Res. (2006) 66:1161-1168.
  • KIM HL, SUN X, SUBJECK JR, WANG XY: Evaluation of renal cell carcinoma vaccines targeting carbonic anhydrase IX using heat shock protein 110. Cancer Immunol. Immunother. (2007) 56:1097-1105.
  • LI Y, SUBJECK J, YANG G, REPASKY E, WANG XY: Generation of anti-tumor immunity using mammalian heat shock protein 70 DNA vaccines for cancer immunotherapy. Vaccine (2006) 24:5360-5370.
  • GOMEZ-GUTIERREZ JG, ELPEK KG, MONTES DE OCA-LUNA R, SHIRWAN H, SAM ZHOU H, MCMASTERS KM: Vaccination with an adenoviral vector expressing calreticulin-human papillomavirus 16 E7 fusion protein eradicates E7 expressing established tumors in mice. Cancer Immunol. Immunother. (2007) 56:997-1007.
  • STRBO N, YAMAZAKI K, LEE K, RUKAVINA D, PODACK ER: Heat shock fusion protein GP96-Ig mediates strong CD8 CTL expansion in vivo. Am. J. Reprod. Immunol. (2002) 48:220-225.
  • SENGUPTA D, NORRIS PJ, SUSCOVICH TJ et al.: Heat shock protein-mediated cross-presentation of exogenous HIV antigen on HLA class I and class II. J. Immunol. (2004) 173:1987-1993.
  • DOODY AD, KOVALCHIN JT, MIHALYO MA, HAGYMASI AT, DRAKE CG, ADLER AJ: Glycoprotein 96 can chaperone both MHC class I- and class II-restricted epitopes for in vivo presentation, but selectively primes CD8+ T cell effector function. J. Immunol. (2004) 172:6087-6092.
  • RAPP UK, KAUFMANN SH: DNA vaccination with GP96-peptide fusion proteins induces protection against an intracellular bacterial pathogen. Int. Immunol. (2004) 16:597-605.
  • TAMURA Y, PENG P, LIU K, DAOU M, SRIVASTAVA PK: Immunotherapy of tumors with autologous tumor-derived heat shock protein preparations. Science (1997) 278:117-120.
  • PARMIANI G, TESTORI A, MAIO M et al.: Heat shock proteins and their use as anticancer vaccines. Clin. Cancer Res. (2004) 10:8142-8146.
  • JANETZKI S, PALLA D, ROSENHAUER V, LOCHS H, LEWIS JJ, SRIVASTAVA PK: Immunization of cancer patients with autologous cancer-derived heat shock protein GP96 preparations: a pilot study. Int. J. Cancer (2000) 88:232-238.
  • BELLI F, TESTORI A, RIVOLTINI L et al.: Vaccination of metastatic melanoma patients with autologous tumor-derived heat shock protein GP96-peptide complexes: clinical and immunologic findings. J. Clin. Oncol. (2002) 20:4169-4180.
  • RICHARDS J, TESTORI A, WHITMAN E et al.: Autologous tumor-derived HSPPC-96 vs. physician's choice (PC) in a randomized Phase III trial in stage IV melanoma. 2006 ASCO Annual Meeting Proceedings. Atlanta, USA (2006) (Abstract 8002).
  • PILLA L, PATUZZO R, RIVOLTINI L et al.: A Phase II trial of vaccination with autologous, tumor-derived heat shock protein peptide complexes GP96, in combination with GM-CSF and interferon-α in metastatic melanoma patients. Cancer Immunol. Immunother. (2006) 55:958-968.
  • MAZZAFERRO V, COPPA J, CARRABBA MG et al.: Vaccination with autologous tumor-derived heat shock protein GP96 after liver resection for metastatic colorectal cancer. Clin. Cancer Res. (2003) 9:3235-3245.
  • RIVOLTINI L, CASTELLI C, CARRABBA M et al.: Human tumor-derived heat shock protein 96 mediates in vitro activation and in vivo expansion of melanoma- and colon carcinoma-specific T cells. J. Immunol. (2003) 171:3467-3474.
  • AMATO R, MURRAY L, WOOD L, SAVARY C, TOMASOVIC S, REITSMA D: Active specific immunotherapy in patients with renal cell carcinoma (RCC) using autologous tumor derived heat shock protein–peptide complex-96 (HSPP-96) vaccine. 1999 ASCO Annual Meeting Proceedings. Atlanta, USA (1999) (Abstract 1278).
  • ASSIKIS VJ, DALIANI D, PAGLIARO L et al.: Phase II study of an autologous tumor derived heat shock protein–peptide complex vaccine (HSPPC-96) for patients with metastatic renal cell carcinoma (mRCC). 2003 ASCO Annual Meeting Proceedings. Chicago, USA (2003) (Abstract 1552).
  • WOOD CG, ESCUDIER B, LACOMBE L et al.: A multicenter randomized Phase III trial of a novel autologous therapeutic vaccine (vitespen) vs observation adjuvant therapy in patients at high-risk of recurrence after nephrectomy for renal cell carcinoma (RCC). Proceedings of the 2007 AUA. Anaheim, CA, USA (2007) (Abstract 633).
  • OKI Y, MCLAUGHLIN P, FAYAD LE et al.: Experience with heat shock protein–peptide complex 96 vaccine therapy in patients with indolent non-Hodgkin lymphoma. Cancer (2007) 109:77-83.
  • HUANG X, REN W, ROLLINS L et al.: A broadly applicable, personalized heat shock protein-mediated oncolytic tumor vaccine. Cancer Res. (2005) 63:7321-7329.
  • WU Y, WAN T, ZHOU X et al.: Hsp70-like protein 1 fusion protein enhances induction of carcinoembryonic antigen-specific CD8+ CTL response by dendritic cell vaccine. Cancer Res. (2005) 65:4947-4954.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.