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Clinical, Cosmetic and Investigational Dermatology Volume 16, 2023 - Issue
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CASE REPORT

Delayed Inflammatory Reactions After Hyaluronic Acid Filling of Neck Lines: A Case Report

Zhiyu Li1 Department of Plastic and Aesthetic Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, People’s Republic of ChinaView further author information
,
Pu Zhao2 Department of Plastic Surgery, Liaocheng Hospital of Traditional Chinese Medicine, Liaocheng, People’s Republic of ChinaView further author information
,
Qing Xu3 Department of Plastic and Aesthetic Surgery, Maternity and Child Health Care of Zaozhuang, Zaozhuang, People’s Republic of ChinaView further author information
,
Jianhai Bi1 Department of Plastic and Aesthetic Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, People’s Republic of China;4 Department of Plastic and Aesthetic Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, People’s Republic of China;5 Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, People’s Republic of ChinaCorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0001-6482-5819View further author information
ORCID Icon &
Ran Huo1 Department of Plastic and Aesthetic Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, People’s Republic of China;4 Department of Plastic and Aesthetic Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, People’s Republic of China;5 Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-3513-1073View further author information
ORCID Icon
Pages 99-102 | Received 28 Oct 2022, Accepted 23 Dec 2022, Published online: 14 Jan 2023

References

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  • Lai D, Liu H, Kong L, Cheng S. Delayed complication of botulinum toxin and hyaluronic acid filler injections: a case report. J Cosmet Dermatol. 2022;21:2374–2378. doi:10.1111/jocd.15016
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  • Cassuto D, Sundaram H. A problem-oriented approach to nodular complications from hyaluronic acid and calcium hydroxylapatite fillers: classification and recommendations for treatment. Plast Reconstr Surg. 2013;132:48S–58S. doi:10.1097/PRS.0b013e31829e52a7
  • Wu L, Liu X, Jian X, et al. Delayed allergic hypersensitivity to hyaluronidase during the treatment of granulomatous hyaluronic acid reactions. J Cosmet Dermatol. 2018;17:991–995. doi:10.1111/jocd.12461
  • Munavalli GG, Guthridge R, Knutsen-Larson S, Brodsky A, Matthew E, Landau M. COVID-19/SARS-CoV-2 virus spike protein-related delayed inflammatory reaction to hyaluronic acid dermal fillers: a challenging clinical conundrum in diagnosis and treatment. Arch Dermatol Res. 2022;314:1–15. doi:10.1007/s00403-021-02190-6
  • Sarigul GS. A case of delayed inflammatory filler reaction following vaccination with successful response to colchicine. J Cosmet Laser Ther. 2021;23:52–54. doi:10.1080/14764172.2021.1967997
  • Munavalli GG, Knutsen-Larson S, Lupo MP, Geronemus RG. Oral angiotensin-converting enzyme inhibitors for treatment of delayed inflammatory reaction to dermal hyaluronic acid fillers following COVID-19 vaccination-a model for inhibition of angiotensin II-induced cutaneous inflammation. JAAD Case Rep. 2021;10:63–68. doi:10.1016/j.jdcr.2021.02.018
  • Artzi O, Cohen JL, Dover JS, et al. Delayed inflammatory reactions to hyaluronic acid fillers: a literature review and proposed treatment algorithm. Clin Cosmet Investig Dermatol. 2020;13:371–378. doi:10.2147/CCID.S247171
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