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Clinical, Cosmetic and Investigational Dermatology Volume 16, 2023 - Issue
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CASE REPORT

Spring-Powered Needle-Free Injection of Triamcinolone Acetonide and 5-Fluorouracil for Keloid Treatment

Eva Krishna SutedjaDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Bandung, West Java, IndonesiaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-2306-8898
ORCID Icon,
Annisa SundaniDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Bandung, West Java, Indonesia
,
Kartika RuchiatanDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Bandung, West Java, IndonesiaORCID Iconhttps://orcid.org/0000-0003-1334-0461
ORCID Icon &
Endang SutedjaDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Bandung, West Java, IndonesiaORCID Iconhttps://orcid.org/0000-0002-6960-4895
ORCID Icon
Pages 1659-1665 | Received 04 Apr 2023, Accepted 13 Jun 2023, Published online: 27 Jun 2023

References

  • Limandjaja GC, Niessen FB, Scheper RJ, Gibbs S. The keloid disorder: heterogeneity, histopathology, mechanisms and models. Front Cell Dev Biol. 2020;8:360. doi:10.3389/fcell.2020.00360
  • Barone N, Safran T, Vorstenbosch J, Davison PG, Cugno S, Murphy AM. Current advances in hypertrophic scar and keloid management. Paper presented at: Seminars in Plastic Surgery; 2021.
  • Finnson KW, McLean S, Di Guglielmo GM, Philip A. Dynamics of transforming growth factor beta signaling in wound healing and scarring. Adv Wound Care. 2013;2(5):195–214. doi:10.1089/wound.2013.0429
  • Shih B, Garside E, McGrouther DA, Bayat A. Molecular dissection of abnormal wound healing processes resulting in keloid disease. Wound Repair Regen. 2010;18(2):139–153. doi:10.1111/j.1524-475X.2009.00553.x
  • Levenberg A, Vinshtok Y, Artzi O. Potentials for implementing pressure-controlled jet injection in management of keloids with intralesional 5FU and corticosteroids. J Cosmet Dermatol. 2020;19(8):1966–1972. doi:10.1111/jocd.13522
  • Slemp AE, Kirschner RE. Keloids and scars: a review of keloids and scars, their pathogenesis, risk factors, and management. Curr Opin Pediatr. 2006;18(4):396–402. doi:10.1097/01.mop.0000236389.41462.ef
  • Mohizin A, Kim JK. Current engineering and clinical aspects of needle-free injectors: a review. J Mech Sci. 2018;32:5737–5747.
  • Ravi AD, Sadhna D, Nagpaal D, Chawla L. Needle free injection technology: a complete insight. Int J Pharm Inv. 2015;5(4):192. doi:10.4103/2230-973X.167662
  • Schramm-Baxter J, Mitragotri S. Needle-free jet injections: dependence of jet penetration and dispersion in the skin on jet power. J Control Release. 2004;97(3):527–535. doi:10.1016/j.jconrel.2004.04.006
  • Alshehari A, Wahdan W, Maamoun MJ. Comparative study between intralesional steroid injection and silicone sheet versus silicone sheet alone in the treatment of pathologic scars. Arch Balkan Med Union. 2015;50:364–366.
  • Han HS, Hong JY, Kwon TR, et al. Mechanism and clinical applications of needle‐free injectors in dermatology: literature review. J Cosmet Dermatol. 2021;20(12):3793–3801. doi:10.1111/jocd.14047
  • Smith N, Cha K, Bichakjian C, et al. Perioperative considerations in dermatology surgery. In: Kang S, Amagai M, Buckner AL, editors. Fitzpatrick’s Dermatology, 9th ed. New York: McGraw-Hill; 2019:3723–3724.
  • Huang C, Wu Z, Du Y, Ogawa R. The epidemiology of keloids. In: Teot L, Mustoe T, Middelkoop E, Gauglitz G, editors. Textbook on Scar Management. Switzerlamnd: Springer; 2020:30–34.
  • Oei F, Putra IB, Jusuf NK. The relationship between skin color and keloid. Bali Med J. 2021;10(2):835–838. doi:10.15562/bmj.v10i2.2619
  • Vivas AC, Tang JC, Maderal AD, Viera MH. Reviews-hypertrophic scars and keloids, part 1: conventional treatments. J Cosmet Dermatol. 2012;25(7):309.
  • Ekstein SF, Wyles SP, Moran SL, Meves A. Keloids: a review of therapeutic management. Int J Dermatol. 2021;60(6):661–671. doi:10.1111/ijd.15159
  • Pratchyapruit W, Vashrangsi N. A new therapeutic modality intralesional 5-fluorouracil in the treatment of keloids and hypertrophic scar. Inst Dermatol Asses. 2012;13(9):157–163.
  • Sharma S, Bassi R, Gupta A. Treatment of small keloids with intralesional 5-fluorouracil alone vs. intralesional triamcinolone acetonide with 5-fluorouracil. J Pak Assoc Dermatol. 2012;22(1):35–40.
  • Wolfram D, Tzankov A, Pülzl P, Piza‐Katzer H. Hypertrophic scars and keloids—a review of their pathophysiology, risk factors, and therapeutic management. Dermatol Surg. 2009;35(2):171–181. doi:10.1111/j.1524-4725.2008.34406.x
  • Khan MA, Bashir MM, Khan FA. Intralesional triamcinolone alone and in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars. J Pak Med Assoc. 2014;64(9):1003–1007.
  • Gauglitz GG, Korting HC, Pavicic T, Ruzicka T, Jeschke MG. Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies. Mol Med. 2011;17(1):113–125. doi:10.2119/molmed.2009.00153
  • Perdanasari AT, Lazzeri D, Su W, et al. Recent developments in the use of intralesional injections keloid treatment. Arc Plast Surg. 2014;41(06):620–629. doi:10.5999/aps.2014.41.6.620
  • Mashiko T, Abo Y, Kuno S, Yoshimura K. A novel facial rejuvenation treatment using pneumatic injection of non–cross-linked hyaluronic acid and hypertonic glucose solution. Dermatol Surg. 2015;41(6):755–758. doi:10.1097/DSS.0000000000000359
  • Baker AB, Sanders JE. Fluid mechanics analysis of a spring-loaded jet injector. IEEE Trans Biomed Eng. 1999;46(2):235–242. doi:10.1109/10.740886
  • Saray Y, Güleç AT. Treatment of keloids and hypertrophic scars with dermojet injections of bleomycin: a preliminary study. Int J Dermatol. 2005;44(9):777–784. doi:10.1111/j.1365-4632.2005.02633.x

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