Erzhiwan Ameliorates Restraint Stress- and Monobenzone-Induced Depigmentation in Mice by Inhibiting Macrophage Migration Inhibitory Factor and 8-Hydroxy-2-Deoxyguanosine

References

• Pei T, Zheng C, Huang C, et al. Systematic understanding the mechanisms of vitiligo pathogenesis and its treatment by qubaibabuqi formula. J Ethnopharmacol. 2016;190:272–287. doi:10.1016/j.jep.2016.06.001
   PubMed Web of Science ®Google Scholar
• Wang Y, Li S, Li C. Clinical features, immunopathogenesis, and therapeutic strategies in vitiligo. Clin Rev Allergy Immunol. 2021;61(3):299–323. doi:10.1007/s12016-021-08868-z
   PubMed Web of Science ®Google Scholar
• Huraib GB, Al Harthi F, Arfin M, Aljamal A, Alrawi AS, Al-Asmari A. Association of functional polymorphism in protein tyrosine phosphatase nonreceptor 22 (PTPN22) gene with vitiligo. Biomark Insights. 2020;15:1177271920903038. doi:10.1177/1177271920903038
   Web of Science ®Google Scholar
• Migayron L, Boniface K, Vitiligo SJ. From physiopathology to emerging treatments: a review. Dermatol Ther. 2020;10(6):1185–1198. doi:10.1007/s13555-020-00447-y
   PubMed Web of Science ®Google Scholar
• Feng Y, Lu Y. Advances in vitiligo: update on therapeutic targets. Front Immunol. 2022;13:986918. doi:10.3389/fimmu.2022.986918
   PubMed Web of Science ®Google Scholar
• Singh M, Kotnis A, Jadeja SD, et al. Cytokines: the yin and yang of vitiligo pathogenesis. Expert Rev Clin Immunol. 2019;15(2):177–188. doi:10.1080/1744666X.2019.1550358
   PubMed Web of Science ®Google Scholar
• Pang Z, Zhi-yan Z, Wang W, et al. The advances in research on the pharmacological effects of fructus ligustri lucidi. Biomed Res Int. 2015;2015:281873. doi:10.1155/2015/281873
   PubMed Web of Science ®Google Scholar
• Timalsina D, Devkota HP. Eclipta prostrata (L.) L. (Asteraceae): ethnomedicinal uses, chemical constituents, and biological activities. Biomolecules. 2021;11(11):1738. doi:10.3390/biom11111738
   PubMed Web of Science ®Google Scholar
• Tang G, Li S, Zhang C, et al. Clinical efficacies, underlying mechanisms and molecular targets of Chinese medicines for diabetic nephropathy treatment and management. Acta Pharm Sin B. 2021;11(9):2749–2767. doi:10.1016/j.apsb.2020.12.020
   PubMed Web of Science ®Google Scholar
• Harris JE. Cellular stress and innate inflammation in organ-specific autoimmunity: lessons learned from vitiligo. Immunol Rev. 2016;269(1):11–25. doi:10.1111/imr.12369
   PubMed Web of Science ®Google Scholar
• Masafi S, Saadat SH, Tehranchi K, et al. Effect of stress, depression and type d personality on immune system in the incidence of coronary artery disease. Open Access Maced J Med Sci. 2018;6(8):1533–1544. doi:10.3889/oamjms.2018.217
   PubMedGoogle Scholar
• Garcia-Orozco A, Martinez-Magaña IA, Riera-Leal A, et al. Macrophage inhibitory factor (MIF) gene polymorphisms are associated with disease susceptibility and with circulating MIF levels in active non-segmental vitiligo in patients from western Mexico. Mol Genet Genomic Med. 2020;8(10):e1416. doi:10.1002/mgg3.1416
   PubMed Web of Science ®Google Scholar
• Alrabadi LS, Dutton A, Rabiee A, et al. Mindfulness-based stress reduction may decrease stress, disease activity, and inflammatory cytokine levels in patients with autoimmune hepatitis. JHEP Rep. 2022;4(5):100450. doi:10.1016/j.jhepr.2022.100450
   PubMedGoogle Scholar
• Li SL, Dai W, Wang SJ, et al. Clinical significance of serum oxidative stress markers to assess disease activity and severity in patients with non-segmental vitiligo. Front Cell Dev Biol. 2021;9:739413. doi:10.3389/fcell.2021.739413
   PubMed Web of Science ®Google Scholar
• Colaianna M, Schiavone S, Zotti M, et al. Neuroendocrine profile in a rat model of psychosocial stress: relation to oxidative stress. Antioxid Redox Signal. 2013;18(12):1385–1399. doi:10.1089/ars.2012.4569
   PubMed Web of Science ®Google Scholar
• Tang N, Liu XT, Wen WL, et al. Restraint stress promotes monobenzone-induced depigmentation in mice via the activation of glucocorticoid receptor/macrophage migration inhibitory factor signaling pathway. Mol Immunol. 2023;161:33–43. doi:10.1016/j.molimm.2023.07.007
   PubMed Web of Science ®Google Scholar
• Mehta H, Kumar S, Parsad D, et al. Oral cyclosporine is effective in stabilizing active vitiligo: results of a randomized controlled trial. Dermatol Ther. 2021;34(5):e15033. doi:10.1111/dth.15033
   PubMed Web of Science ®Google Scholar
• van den Boorn JG, Konijnenberg D, Tjin EP, et al. Effective melanoma immunotherapy in mice by the skin-depigmenting agent monobenzone and the adjuvants imiquimod and CpG. PLoS One. 2010;5(5):e10626. doi:10.1371/journal.pone.0010626
   PubMed Web of Science ®Google Scholar
• Schrader J, Deuster O, Rinn B, et al. Restoration of contact inhibition in human glioblastoma cell lines after MIF knockdown. BMC Cancer. 2009;9(1):464. doi:10.1186/1471-2407-9-464
   PubMedGoogle Scholar
• Han J, Hou J, Liu Y, et al. Using network pharmacology to explore the mechanism of panax notoginseng in the treatment of myocardial fibrosis. J Diabetes Res. 2022;2022:8895950. doi:10.1155/2022/8895950
   PubMed Web of Science ®Google Scholar
• Pan HT, Xi ZQ, Wei XQ, et al. A network pharmacology approach to predict potential targets and mechanisms of “ramulus cinnamomi (cassiae) – Paeonia lactiflora” herb pair in the treatment of chronic pain with comorbid anxiety and depression. Ann Med. 2022;54(1):413–425. doi:10.1080/07853890.2022.2031268
   PubMed Web of Science ®Google Scholar
• Xie YY, Yan B, Hou M, et al. Erzhi pills ameliorate cognitive dysfunction and alter proteomic hippocampus profiles induced by d-galactose and aβ 1–40 injection in ovariectomized alzheimer’s disease model rats. Pharm Biol. 2021;59(1):1402–1414. doi:10.1080/13880209.2021.1990353
   PubMed Web of Science ®Google Scholar
• Berbert Ferreira S, Berbert Ferreira R, Neves Neto AC, et al. Topical tofacitinib: a janus kinase inhibitor for the treatment of vitiligo in an adolescent patient. Case Rep Dermatol. 2021;13(1):190–194. doi:10.1159/000513938
   PubMed Web of Science ®Google Scholar
• Tuna A, Ozturk G, Gerceker TB, et al. Superoxide dismutase 1 and 2 gene polymorphism in Turkish vitiligo patients. Balkan J Med Genet. 2017;20(2):67–73. doi:10.1515/bjmg-2017-0033
   PubMed Web of Science ®Google Scholar
• Chen LY, Wang Y, Terkeltaub R, et al. Activation of AMPK-SIRT3 signaling is chondroprotective by preserving mitochondrial DNA integrity and function. Osteoarthritis Cartilage. 2018;26(11):1539–1550. doi:10.1016/j.joca.2018.07.004
   PubMed Web of Science ®Google Scholar
• Snodgrass RG, Benatzy Y, Schmid T, et al. Efferocytosis potentiates the expression of arachidonate 15-lipoxygenase (ALOX15) in alternatively activated human macrophages through LXR activation. Cell Death Differ. 2021;28(4):1301–1316. doi:10.1038/s41418-020-00652-4
   PubMed Web of Science ®Google Scholar
• Le Hiress M, Tu L, Ricard N, et al. Proinflammatory signature of the dysfunctional endothelium in pulmonary hypertension. role of the macrophage migration inhibitory factor/CD74 complex. Am J Respir Crit Care Med. 2015;192(8):983–997. doi:10.1164/rccm.201402-0322OC
   PubMed Web of Science ®Google Scholar
• Li W, Sultana N, Yuan L, et al. CD74 in apoptotic macrophages is associated with inflammation, plaque progression and clinical manifestations in human atherosclerotic lesions. Metabolites. 2022;12(1):54. doi:10.3390/metabo12010054
   PubMed Web of Science ®Google Scholar
• Hu D, Huang S, Ding Y, et al. Specnuezhenide reduces carbon tetrachloride-induced liver injury in mice through inhibition of oxidative stress and hepatocyte apoptosis. J Pharm Pharmacol. 2022;74(2):191–199. doi:10.1093/jpp/rgab164
   PubMed Web of Science ®Google Scholar
• Wang QQ, Han S, Li XX, et al. Nuezhenide exerts anti-inflammatory activity through the NF-κB pathway. Curr Mol Pharmacol. 2021;14(1):101–111. doi:10.2174/1874467213666200611141337
   PubMed Web of Science ®Google Scholar
• Yin R, Xue J, Tan Y, et al. The positive role and mechanism of herbal medicine in parkinson’s disease. Oxid Med Cell Longev. 2021;2021:9923331. doi:10.1155/2021/9923331
   PubMed Web of Science ®Google Scholar
• Nyakudya TT, Mukwevho E, Erlwanger KH. The protective effect of neonatal oral administration of oleanolic acid against the subsequent development of fructose-induced metabolic dysfunction in male and female rats. Nutr Metab. 2018;15(1):82. doi:10.1186/s12986-018-0314-7
   Google Scholar
• Proshkina E, Plyusnin S, Babak T, et al. Terpenoids as potential geroprotectors. Antioxidants. 2020;9(6):529. doi:10.3390/antiox9060529
   Web of Science ®Google Scholar
• Wang XQ, Liu RP, Wang J, et al. Wedelolactone facilitates the early development of parthenogenetically activated porcine embryos by reducing oxidative stress and inhibiting autophagy. PeerJ. 2022;10:e13766. doi:10.7717/peerj.13766
   PubMed Web of Science ®Google Scholar
• Pan H, Lin Y, Dou J, et al. Wedelolactone facilitates ser/thr phosphorylation of NLRP3 dependent on PKA signalling to block inflammasome activation and pyroptosis. Cell Prolif. 2020;53(9):e12868. doi:10.1111/cpr.12868
   PubMed Web of Science ®Google Scholar