135
Views
0
CrossRef citations to date
0
Altmetric
CASE REPORT

Successful Treatment of Granulomatous Rosacea by JAK Inhibitor Abrocitinib: A Case Report

ORCID Icon, , ORCID Icon, , ORCID Icon & ORCID Icon
Pages 3369-3374 | Received 13 Sep 2023, Accepted 11 Nov 2023, Published online: 20 Nov 2023

References

  • Uliandri J, Wang X, Liu Z, et al. Global rosacea treatment guidelines and expert consensus points: the differences. J Cosmet Dermatol. 2019;18(4):960–965.
  • Van Zuuren EJ, Arents BWM, van der Linden MMD, et al. Rosacea: new concepts in classification and treatment. Am J Clin Dermatol. 2021;22(4):457–465. doi:10.1007/s40257-021-00595-7
  • Jang YJ, Hong EH, Park EJ, et al. Immunohistochemical analysis of differences of toll-like receptor 2, mast cells, and neurofilaments between granulomatous rosacea and non-granulomatous rosacea. Indian J Dermatol. 2021;66(4):343–346. doi:10.4103/ijd.IJD_18_20
  • Mullanax MG, Kierland RR. Granulomatous rosacea. Arch Dermatol. 1970;101(2):206–211. doi:10.1001/archderm.1970.04000020076011
  • Slater N, Rapini RP. Lupus miliaris disseminatus faciei. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023.
  • Lee GL, Zirwas MJ. Granulomatous rosacea and periorificial dermatitis: controversies and review of management and treatment. Dermatol Clin. 2015;33(3):447–455. doi:10.1016/j.det.2015.03.009
  • Lane JE, Khachemoune A. Use of intense pulsed light to treat refractory granulomatous rosacea. Dermatol Surg. 2010;36(4):571–573. doi:10.1111/j.1524-4725.2010.01503.x
  • Sun YH, Man XY, Xuan XY, et al. Tofacitinib for the treatment of erythematotelangiectatic and papulopustular rosacea: a retrospective case series. Dermatol Ther. 2022;35(11):e15848. doi:10.1111/dth.15848
  • Li T, Wang H, Wang C, et al. Tofacitinib for the treatment of steroid-induced rosacea. Clin Cosmet Investig Dermatol. 2022;15:2519–2521. doi:10.2147/CCID.S392280
  • Hu X, Li J, Fu M, et al. The JAK/STAT signaling pathway: from bench to clinic. Signal Transduct Target Ther. 2021;6(1):402. doi:10.1038/s41392-021-00791-1
  • Xin P, Xu X, Deng C, et al. The role of JAK/STAT signaling pathway and its inhibitors in diseases. Int Immunopharmacol. 2020;80:106210. doi:10.1016/j.intimp.2020.106210
  • McLornan DP, Pope JE, Gotlib J, et al. Current and future status of JAK inhibitors. Lancet. 2021;398(10302):803–816. doi:10.1016/S0140-6736(21)00438-4
  • Deeks ED, Duggan S. Abrocitinib: first approval. Drugs. 2021;81(18):2149–2157. doi:10.1007/s40265-021-01638-3
  • Li T, Zeng Q, Chen X, et al. The therapeutic effect of artesunate on rosacea through the inhibition of the JAK/STAT signaling pathway. Mol Med Rep. 2018;17(6):8385–8390. doi:10.3892/mmr.2018.8887
  • Kumari A, Srivastava A, Jagdale P, et al. Lambda-cyhalothrin enhances inflammation in nigrostriatal region in rats: regulatory role of NF-κβ and JAK-STAT signaling. Neurotoxicology. 2023;96:101–117. doi:10.1016/j.neuro.2023.04.003
  • Zhou J, Li T, Chen H, et al. ADAMTS10 inhibits aggressiveness via JAK/STAT/c-MYC pathway and reprograms macrophage to create an anti-malignant microenvironment in gastric cancer. Gastric Cancer. 2022;25(6):1002–1016. doi:10.1007/s10120-022-01319-4
  • Zhang Y, Li Y, Zhou L, et al. Nav1.8 in keratinocytes contributes to ROS-mediated inflammation in inflammatory skin diseases. Redox Biol. 2022;55:102427. doi:10.1016/j.redox.2022.102427
  • Shen S, Yan G, Cao Y, et al. Dietary supplementation of n-3 PUFAs ameliorates LL37-induced rosacea-like skin inflammation via inhibition of TLR2/MyD88/NF-κB pathway. Biomed Pharmacother. 2023;157:114091. doi:10.1016/j.biopha.2022.114091