Advanced search
Publication Cover
International Journal of Chronic Obstructive Pulmonary Disease Volume 14, 2019 - Issue
Submit an article Journal homepage
230
Views
12
CrossRef citations to date
0
Altmetric
Original Research

Contributions of cardiovascular risk and smoking to chronic obstructive pulmonary disease (COPD)-related changes in brain structure and function

Catherine A Spilling1 Institute for Molecular and Clinical Sciences, St George’s University of London, LondonSW17 ORE, UKORCID Iconhttps://orcid.org/0000-0002-6908-5079
ORCID Icon,
Mohani-Preet K Bajaj1 Institute for Molecular and Clinical Sciences, St George’s University of London, LondonSW17 ORE, UKORCID Iconhttps://orcid.org/0000-0001-8797-6855
ORCID Icon,
Daniel R Burrage2 Institute for Infection and Immunity, St George’s University of London, LondonSW17 ORE, UKORCID Iconhttps://orcid.org/0000-0002-6128-9202
ORCID Icon,
Sachelle Ruickbie2 Institute for Infection and Immunity, St George’s University of London, LondonSW17 ORE, UK
,
N Jade Thai3 Clinical Research and Imaging Centre, University of Bristol, BristolBS2 8DX, UKORCID Iconhttps://orcid.org/0000-0001-6125-7326
ORCID Icon,
Emma H Baker2 Institute for Infection and Immunity, St George’s University of London, LondonSW17 ORE, UKORCID Iconhttps://orcid.org/0000-0002-0871-3721
ORCID Icon,
Paul W Jones2 Institute for Infection and Immunity, St George’s University of London, LondonSW17 ORE, UKORCID Iconhttps://orcid.org/0000-0001-6087-9182
ORCID Icon,
Thomas R Barrick1 Institute for Molecular and Clinical Sciences, St George’s University of London, LondonSW17 ORE, UK
&
James W Dodd4 Academic Respiratory Unit, University of Bristol, BristolBS10 5NB, UKCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-4805-5759
ORCID Icon show all
Pages 1855-1866 | Published online: 21 Aug 2019

References

  • Cavaillès A, Brinchault-Rabin G, Dixmier A, et al. Comorbidities of COPD. Eur Respir Rev Off J Eur Respir Soc 2013;22(130):454–475. doi: 10.1183/09059180.00008612
  • Laforest L, Roche N, Devouassoux G, et al. Frequency of comorbidities in chronic obstructive pulmonary disease, and impact on all-cause mortality: a population-based cohort study. Respir Med 2016;117:33–39. doi:10.1016/j.rmed.2016.06.01527492511
  • Agusti A, Calverley PM, Celli B, et al. Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respir Res 2010;11(1):122. doi:10.1186/1465-9921-11-6220831787
  • Mannino DM, Thorn D, Swensen A, Holguin F Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD. Eur Respir J 2008;32(4):962–969. doi:10.1183/09031936.0001240818579551
  • Sin DD, Anthonisen NR, Soriano JB, Agusti AG Mortality in COPD: role of comorbidities. Eur Respir J 2006;28(6):1245–1257. doi:10.1183/09031936.0013380517138679
  • Huber MB, Wacker ME, Vogelmeier CF, Leidl R Excess costs of comorbidities in chronic obstructive pulmonary disease: a systematic review. PLoS One 2015;10(4). doi:10.1371/journal.pone.0123292
  • Miller J, Edwards LD, Agustí A, et al. Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort. Respir Med 2013;107(9):1376–1384. doi:10.1016/j.rmed.2013.05.00123791463
  • Yohannes AM, Alexopoulos GS Depression and anxiety in patients with COPD. Eur Respir Rev 2014;23(133):345–349. doi:10.1183/09059180.0000781325176970
  • Dodd JW, Getov SV, Jones PW Cognitive function in COPD. Eur Respir J 2010;35(4):913–922. doi:10.1183/09031936.0012510920356988
  • Pumar MI, Gray CR, Walsh JR, Yang IA, Rolls TA, Ward DL Anxiety and depression-Important psychological comorbidities of COPD. J Thorac Dis 2014;6(11):1615–1631.25478202
  • Chang SS, Chen S, McAvay GJ, Tinetti ME Effect of coexisting chronic obstructive pulmonary cisease and cognitive impairment on health outcomes in older adults. J Am Geriatr Soc 2012;60(10):1839–1846. doi:10.1111/j.1532-5415.2012.04171.x23035917
  • Kim H, Kunik ME, Molinari VA, et al. Functional impairment in COPD patients: the impact of anxiety and depression. Psychosomatics 2000;41(6):465–471. doi:10.1176/appi.psy.41.6.46511110109
  • Incalzi RA Verbal memory impairment in copd: its mechanisms and clinical relevance. Chest J 1997;112(6):1506. doi:10.1378/chest.112.6.1506
  • Laurin C, Moullec G, Bacon SL, Lavoie KL Impact of anxiety and depression on chronic obstructive pulmonary disease exacerbation risk. Am J Respir Crit Care Med 2012;185(9):918–923. doi:10.1164/rccm.201105-0939PP22246177
  • van Dijk EJ. Arterial oxygen saturation, COPD, and cerebral small vessel disease. J Neurol Neurosurg Psychiatry 2004;75(5):733–736. doi:10.1136/jnnp.2003.02201215090569
  • Lahousse L, Vernooij MW, Darweesh SKL, et al. Chronic obstructive pulmonary disease and cerebral microbleeds. The Rotterdam study. Am J Respir Crit Care Med 2013;188(7):783–788. doi:10.1164/rccm.201303-0455OC23885754
  • Ryu CW, Jahng GH, Choi CW, et al. Microstructural change of the brain in chronic obstructive pulmonary disease. COPD J Chronic Obstr Pulm Dis.2013;10(3):357–366. doi:10.3109/15412555.2012.752808
  • Zhang H, Wang X, Lin J, et al. Reduced regional gray matter volume in patients with chronic obstructive pulmonary disease: a voxel-based morphometry study. Am J Neuroradiol 2013;34(2):334–339. doi:10.3174/ajnr.A323522859277
  • Zhang H, Wang X, Lin J, et al. Grey and white matter abnormalities in chronic obstructive pulmonary disease: a case-control study. BMJ Open 2012;2(2):e000844–e000844. doi:10.1136/bmjopen-2012-000844
  • Esser RW, Stoeckel MC, Kirsten A, et al. Structural brain changes in patients with COPD. Chest 2016;149(2):426–434. doi:10.1378/chest.15-002726203911
  • Wang C, Ding Y, Shen B, et al. Altered gray matter volume in stable chronic obstructive pulmonary disease with subclinical cognitive impairment: an exploratory study. Neurotox Res 2017;31(4):453–463. doi:10.1007/s12640-016-9690-928005183
  • Dodd JW, Chung AW, Broek MD, van Den BTR, Charlton RA, Jones PW Brain structure and function in chronic obstructive pulmonary disease: a multimodal cranial magnetic resonance imaging study. Am J Respir Crit Care Med 2012;186(3):240–245. doi:10.1164/rccm.201202-0355OC22652026
  • Chen J, Lin I-T, Zhang H, et al. Reduced cortical thickness, surface area in patients with chronic obstructive pulmonary disease: a surface-based morphometry and neuropsychological study. Brain Imaging Behav 2015; 10(2)464–476. doi:10.1007/s11682-015-9403-7
  • Li J, Fei G-H The unique alterations of hippocampus and cognitive impairment in chronic obstructive pulmonary disease. Respir Res 2013;14(140):1–9. doi:10.1186/1465-9921-14-1923289668
  • Spilling CA, Jones PW, Dodd JW, Barrick TR. White matter lesions characterise brain involvement in moderate to severe chronic obstructive pulmonary disease, but cerebral atrophy does not. BMC Pulm Med 2017;17(1):92. doi:10.1186/s12890-017-0500-928629404
  • Liao D, Higgins M, Bryan NR, et al. Lower pulmonary function and cerebral subclinical abnormalities detected by MRI: the atherosclerosis risk in communities study. Chest 1999;116(1):150–156. doi:10.1378/chest.116.1.15010424519
  • Murray AD, Staff RT, Shenkin SD, Deary IJ, Starr JM, Whalley LJ Brain white matter hyperintensities: relative importance of vascular risk factors in nondemented elderly people. Radiology 2005;237(1):251–257. doi:10.1148/radiol.237104149616126931
  • Taki Y, Kinomura S, Ebihara S, et al. Correlation between pulmonary function and brain volume in healthy elderly subjects. Neuroradiology 2013;55(6):689–695. doi:10.1007/s00234-013-1157-623440433
  • Sachdev PS, Anstey KJ, Parslow RA, et al. Pulmonary function, cognitive impairment and brain atrophy in a middle-aged community sample. Dement Geriatr Cogn Disord 2006; 21 (5–6): 300–308. doi:10.1159/00009143816484809
  • Esser RW, Stoeckel MC, Kirsten A, et al. Brain activation during perception and anticipation of dyspnea in chronic obstructive pulmonary disease. Front Physiol 2017 cited 2019 April 4];8 Available from: http://journal.frontiersin.org/article/10.3389/fphys.2017.00617/full
  • Herigstad M, Faull OK, Hayen A, et al. Treating breathlessness via the brain: changes in brain activity over a course of pulmonary rehabilitation. Eur Respir J 2017;50(3):1701029. doi:10.1183/13993003.00711-201728899937
  • Herigstad M, Hayen A, Evans E, et al. Dyspnea-related cues engage the prefrontal cortex: evidence from functional brain imaging in COPD. Chest J 2015; 148(4):953 doi:10.1378/chest.15-0416
  • Wardlaw JM, Smith C, Dichgans M Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging Lancet Neurol 2013;12(5):483–497. doi:10.1016/S1474-4422(13)70060-723602162
  • Pantoni L Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. Lancet Neurol 2010;9(7):689–701. doi:10.1016/S1474-4422(10)70104-620610345
  • Miller MR, Hankinson J, Brusasco V, et al. Standardisation of spirometry. Eur Respir J 2005;26(2):319–338. doi:10.1183/09031936.05.0003480516055882
  • Jones PW, Harding G, Berry P, Wiklund I, Chen W-H, Kline Leidy N Development and first validation of the COPD assessment test. Eur Respir J 2009;34(3):648–654. doi:10.1183/09031936.0010250919720809
  • Zigmond AS, Snaith RP The hospital anxiety and depression scale. Acta Psychiatr Scand 1983;67(6):361–370. doi:10.1111/acp.1983.67.issue-66880820
  • Nasreddine ZS, Phillips NA, Bédirian V, et al. The montreal cognitive assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc 2005;53(4):695–699. doi:10.1111/j.1532-5415.2005.53221.x15817019
  • Pauca AL, O’Rourke MF, Kon ND Prospective evaluation of a method for estimating ascending aortic pressure from the radial artery pressure waveform. Hypertens Dallas Tex 1979 2001;38(4):932–937.
  • Lilienthal JL, Riley RL On the determination of arterial oxygen saturations from samples of “capillary” blood. J Clin Invest 1944;23(6):904–906. doi:10.1172/JCI10156516695176
  • Lambert C, Sam Narean J, Benjamin P, Zeestraten E, Barrick TR, Markus HS Characterising the grey matter correlates of leukoaraiosis in cerebral small vessel disease. NeuroImage Clin 2015;9:194–205. doi:10.1016/j.nicl.2015.07.00226448913
  • Lahousse L, Tiemeier H, Ikram MA, Brusselle GG Chronic obstructive pulmonary disease and cerebrovascular disease: a comprehensive review. Respir Med 2015;109(11):1371–1380. doi:10.1016/j.rmed.2015.07.01426342840
  • Scahill RI, Frost C, Jenkins R, Whitwell JL, Rossor MN, Fox NC A longitudinal study of brain volume changes in normal aging using serial registered magnetic resonance imaging. Arch Neurol 2003;60:989–994. doi:10.1001/archneur.60.7.98912873856
  • Taki Y, Thyreau B, Kinomura S, et al. Correlations among brain gray matter volumes, age, gender, and hemisphere in healthy individuals. PLoS One 2011;6:e22734. doi:10.1371/journal.pone.002273421818377
  • Aljondi R, Szoeke C, Steward C, Yates P, Desmond P A decade of changes in brain volume and cognition. Brain Imaging Behav 2019;13:554–563. doi:10.1007/s11682-018-9887-z29744801
  • Nitkunan A, Lanfranconi S, Charlton RA, Barrick TR, Markus HS Brain atrophy and cerebral small vessel disease: a prospective follow-up study. Stroke 2011;42:133–138. doi:10.1161/STROKEAHA.110.59426721148440
  • Kooistra M, Geerlings MI, Mali WPTM, Vincken KL, van der Graaf Y, Biessels GJ Diabetes mellitus and progression of vascular brain lesions and brain atrophy in patients with symptomatic atherosclerotic disease. The SMART-MR study. J Neurol Sci 2013;332:69–74. doi:10.1016/j.jns.2013.06.01923835088
  • Cleutjens FAHM, Ponds RWHM, Spruit MA, et al. The relationship between cerebral small vessel disease, hippocampal volume and cognitive functioning in patients with COPD: an MRI study. Front Aging Neurosci 2017;9. doi:10.3389/fnagi.2017.00077
  • Hynninen KMJ, Breitve MH, Wiborg AB, Pallesen S, Nordhus IH Psychological characteristics of patients with chronic obstructive pulmonary disease: a review. J Psychosom Res 2005;59(6):429–443. doi:10.1016/j.jpsychores.2005.04.00716310027
  • Alexopoulos GS, Kiosses DN, Choi SJ, Murphy CF, Lim KO Frontal white matter microstructure and treatment response of late-life depression: a preliminary study. Am J Psychiatry 2002;159(11):1929–1932. doi:10.1176/appi.ajp.159.11.192912411231
  • Teodorczuk A, Firbank MJ, Pantoni L, et al. Relationship between baseline white-matter changes and development of late-life depressive symptoms: 3-year results from the LADIS study. Psychol Med 2010;40(4):603–610. doi:10.1017/S003329170999085719671212
  • Emsell L, Adamson C, De Winter F-L, et al. Corpus callosum macro and microstructure in late-life depression. J Affect Disord 2017;222:63–70. doi:10.1016/j.jad.2017.06.06328672181
  • Alexopoulos GS, Murphy CF, Gunning-Dixon FM, et al. Microstructural white matter abnormalities and remission of geriatric depression. Am J Psychiatry 2008;165(2):238–244. doi:10.1176/appi.ajp.2007.0705074418172016
  • Qiu WQ, Himali JJ, Wolf PA, DeCarli DC, Beiser A, Au R Effects of white matter integrity and brain volumes on late life depression in the Framingham Heart Study. Int J Geriatr Psychiatry 2017;32(2):214–221. doi:10.1002/gps.v32.227059548
  • van Agtmaal MJM, Houben AJHM, Pouwer F, Stehouwer CDA, Schram MT Association of microvascular dysfunction with late-life depression: a systematic review and meta-analysis. JAMA Psychiatry 2017;74(7):729–739. doi:10.1001/jamapsychiatry.2017.098428564681
  • Brookes RL, Herbert V, Lawrence AJ, Morris RG, Markus HS Depression in small-vessel disease relates to white matter ultrastructural damage, not disability. Neurology 2014;83(16):1417–1423. doi:10.1212/WNL.000000000000088225230999
  • Hollocks MJ, Lawrence AJ, Brookes RL, et al. Differential relationships between apathy and depression with white matter microstructural changes and functional outcomes. Brain 2015;138(12):3803–3815. doi:10.1093/brain/awu35326490330
  • Lohner V, Brookes RL, Hollocks MJ, Morris RG, Markus HS Apathy, but not depression, is associated with executive dysfunction in cerebral small vessel disease. PLoS One 2017;12(5). doi:10.1371/journal.pone.0176943
  • Martin CR What does the Hospital Anxiety and Depression Scale (HADS) really measure in liaison psychiatry settings? Curr Psychiatry Rev. 2004 [ cited 2019 April 15]. Available from: http://www.eurekaselect.com/79829/article.
  • Djukanovic I, Carlsson J, Årestedt K Is the Hospital Anxiety and Depression Scale (HADS) a valid measure in a general population 65–80 years old? A psychometric evaluation study. Health Qual Life Outcomes 2017;15. doi:10.1186/s12955-017-0759-9
  • Crawford JR, Henry JD, Crombie C, Taylor EP Normative data for the HADS from a large non-clinical sample. Br J Clin Psychol 2001;40(4):429–434.11760618
  • Pallant JF, Tennant A An introduction to the Rasch measurement model: an example using the Hospital Anxiety and Depression Scale (HADS). Br J Clin Psychol 2007;46(1):1–18. doi:10.1348/014466506X15899617472198
  • Martin CR, Tweed AE, Metcalfe MS A psychometric evaluation of the Hospital Anxiety and Depression Scale in patients diagnosed with end-stage renal disease. Br J Clin Psychol 2004;43(Pt 1):51–64. doi:10.1348/01446650477281296815005906

References

  • Zigmond AS, Snaith RP The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67(6):361–370. doi:10.1111/acp.1983.67.issue-66880820
  • Nasreddine ZS, Phillips NA, Bédirian V, et al. The montreal cognitive assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc. 2005;53(4):695–699. doi:10.1111/j.1532-5415.2005.53221.x15817019
  • Villenueve S, Pepin V, Rahayel S, et al. Mild cognitive impairment in moderate to severe COPD: a preliminary study. Chest. 2012;146(6):1516–1523. doi:10.1378/chest.11-3035
  • Avants BB, Tustison N, Song G Advanced normalization tools (ANTS). Insight J. 2009 [ cited 2014 March 12]. Available from: ftp://ftp3.ie.freebsd.org/pub/sourceforge/a/project/ad/advants/Documentation/ants.pdf.
  • Spilling CA, Jones PW, Dodd JW, Barrick TR White matter lesions characterise brain involvement in moderate to severe chronic obstructive pulmonary disease, but cerebral atrophy does not. BMC Pulm Med. 2017 [ cited 2018 August 14];17(1). doi:10.1186/s12890-017-0500-9
  • Lambert C, Sam Narean J, Benjamin P, Zeestraten E, Barrick TR, Markus HS Characterising the grey matter correlates of leukoaraiosis in cerebral small vessel disease. NeuroImage Clin. 2015;9:194–205. doi:10.1016/j.nicl.2015.07.00226448913
  • Andersson JLR, Sotiropoulos SN An integrated approach to correction for off-resonance effects and subject movement in diffusion MR imaging. Neuroimage. 2016;125:1063–1078. doi:10.1016/j.neuroimage.2015.10.01926481672
  • Jenkinson M, Beckmann CF, Behrens TEJ, Woolrich MW, Smith SM. FSL NeuroImage 2012;62(2):782–790. doi:10.1016/j.neuroimage.2011.09.01521979382
  • Smith SM Fast robust automated brain extraction. Hum Brain Mapp 2002;17(3):143–155. doi:10.1002/(ISSN)1097-019312391568
  • Greve DN, Fischl B Accurate and robust brain image alignment using boundary-based registration. NeuroImage 2009;48(1):63–72. doi:10.1016/j.neuroimage.2009.06.06019573611

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.