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Original Research

Blood Neutrophils In COPD But Not Asthma Exhibit A Primed Phenotype With Downregulated CD62L Expression

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Pages 2517-2525 | Published online: 15 Nov 2019

References

  • Siddiqui S, Brightling CE. Airways disease: phenotyping heterogeneity using measures of airway inflammation. Allergy Asthma Clin Immunol. 2007;3(2):60–69. doi:10.1186/1710-1492-3-2-6020525145
  • Simpson JL, Phipps S, Gibson PG. Inflammatory mechanisms and treatment of obstructive airway diseases with neutrophilic bronchitis. Pharmacol Ther. 2009;124(1):86–95. doi:10.1016/j.pharmthera.2009.06.00419555716
  • Demkow U, van Overveld FJ. Role of elastases in the pathogenesis of chronic obstructive pulmonary disease: implications for treatment. Eur J Med Res. 2010;15(Suppl 2):27–35. doi:10.1186/2047-783x-15-s2-2721147616
  • Shaw DE, Berry MA, Hargadon B, et al. Association between neutrophilic airway inflammation and airflow limitation in adults with asthma. Chest. 2007;132(6):1871–1875. doi:10.1378/chest.07-104717925424
  • Rosales C. Neutrophil: a cell with many roles in inflammation or several cell types? Front Physiol. 2018;9:113. doi:10.3389/fphys.2018.0011329515456
  • Amulic B, Cazalet C, Hayes GL, Metzler KD, Zychlinsky A. Neutrophil function: from mechanisms to disease. Annu Rev Immunol. 2012;30:459–489. doi:10.1146/annurev-immunol-020711-07494222224774
  • Viola A, Luster AD. Chemokines and their receptors: drug targets in immunity and inflammation. Annu Rev Pharmacol Toxicol. 2008;48:171–197. doi:10.1146/annurev.pharmtox.48.121806.15484117883327
  • Vaguliene N, Zemaitis M, Lavinskiene S, Miliauskas S, Sakalauskas R. Local and systemic neutrophilic inflammation in patients with lung cancer and chronic obstructive pulmonary disease. BMC Immunol. 2013;14:36. doi:10.1186/1471-2172-14-3623919722
  • Fortunati E, Kazemier KM, Grutters JC, Koenderman L, Van Den Bosch VJMM. Human neutrophils switch to an activated phenotype after homing to the lung irrespective of inflammatory disease. Clin Exp Immunol. 2009;155(3):559–566. doi:10.1111/j.1365-2249.2008.03791.x19077082
  • Mallia P, Message SD, Contoli M, et al. Neutrophil adhesion molecules in experimental rhinovirus infection in COPD. Respir Res. 2013;14(1):72. doi:10.1186/1465-9921-14-7223834268
  • Hyun Y-M, Lefort CT, Kim M. Leukocyte integrins and their ligand interactions. Immunol Res. 2009;45(2–3):195–208. doi:10.1007/s12026-009-8101-119184539
  • Sadhu C, Ting HJ, Lipsky B, et al. CD11c/CD18: novel ligands and a role in delayed-type hypersensitivity. J Leukoc Biol. 2007;81(6):1395–1403. doi:10.1189/jlb.110668017389580
  • Wang JH, Sexton DM, Redmond HP, Watson RW, Croke DT, Bouchier-Hayes D. Intercellular adhesion molecule-1 (ICAM-1) is expressed on human neutrophils and is essential for neutrophil adherence and aggregation. Shock. 1997;8(5):357–361. doi:10.1097/00024382-199711000-000079361346
  • Wang S, Dangerfield JP, Young RE, Nourshargh S. PECAM-1, alpha6 integrins and neutrophil elastase cooperate in mediating neutrophil transmigration. J Cell Sci. 2005;118(Pt 9):2067–2076. doi:10.1242/jcs.0234015840647
  • Oudijk EJ, Lammers JW, Koenderman L. Systemic inflammation in chronic obstructive pulmonary disease. Eur Respir J Suppl. 2003;46:5s–13s.14621102
  • Sokol CL, Luster AD. The chemokine system in innate immunity. Cold Spring Harb Perspect Biol. 2015; 7(5):a016303. doi:10.1101/cshperspect.a01630325635046
  • Yao Y, Matsushima H, Ohtola JA, Geng S, Lu R, Takashima A. Neutrophil priming occurs in a sequential manner and can be visualized in living animals by monitoring IL-1β promoter activation. J Immunol. 2015;194(3):1211–1224. doi:10.4049/jimmunol.140201825527787
  • Hafezi-Moghadam A, Thomas KL, Prorock AJ, Huo Y, Ley K. L-selectin shedding regulates leukocyte recruitment. J Exp Med. 2001;193(7):863–872. doi:10.1084/jem.193.7.86311283159
  • Blidberg K, Palmberg L, James A, et al. Adhesion molecules in subjects with COPD and healthy non-smokers: a cross sectional parallel group study. Respir Res. 2013;14:47. doi:10.1186/1465-9921-14-1923635004
  • Lokwani R, Wark PAB, Baines KJ, Barker D, Simpson JL. Hypersegmented airway neutrophils and its association with reduced lung function in adults with obstructive airway disease: an exploratory study. BMJ Open. 2019;9(1):e024330. doi:10.1136/bmjopen-2018-024330
  • Pillay J, Kamp VM, van Hoffen E, et al. A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1. J Clin Invest. 2012;122(1):327–336. doi:10.1172/JCI5799022156198
  • Tak T, Wijten P, Heeres M, et al. Human CD62L(dim) neutrophils identified as a separate subset by proteome profiling and in vivo pulse-chase labeling. Blood. 2017;129(26):3476–3485. doi:10.1182/blood-2016-07-72766928515092
  • Hao S, Andersen M, Yu H. Detection of immune suppressive neutrophils in peripheral blood samples of cancer patients. Am J Blood Res. 2013;3(3):239–245.23997986
  • Millrud CR, Kågedal Å, Kumlien Georén S, et al. NET-producing CD16high CD62Ldim neutrophils migrate to tumor sites and predict improved survival in patients with HNSCC. Int J Cancer. 2017;140(11):2557–2567. doi:10.1002/ijc.3067128247912
  • Pitzer JE, Del Zoppo GJ, Schmid-Schonbein GW. Neutrophil activation in smokers. Biorheology. 1996;33(1):45–58.8869343
  • Gibson PG, Wlodarczyk JW, Hensley MJ, et al. Epidemiological association of airway inflammation with asthma symptoms and airway hyperresponsiveness in childhood. Am J Respir Crit Care Med. 1998;158(1):36–41. doi:10.1164/ajrccm.158.1.97050319655704
  • Chen Y, Junger WG. Measurement of oxidative burst in neutrophils. Methods Mol Biol. 2012;844:115–124.22262438
  • Mann BS, Chung KF. Blood neutrophil activation markers in severe asthma: lack of inhibition by prednisolone therapy. Respir Res. 2006;7:59. doi:10.1186/1465-9921-7-5916600024
  • Wittmann S, Rothe G, Schmitz G, Frohlich D. Cytokine upregulation of surface antigens correlates to the priming of the neutrophil oxidative burst response. Cytometry Part A. 2004;57(1):53–62. doi:10.1002/cyto.a.10108
  • Miralda I, Uriarte SM, McLeish KR. Multiple phenotypic changes define neutrophil priming. Front Cell Infect Microbiol. 2017;7:217. doi:10.3389/fcimb.2017.0021728611952
  • Condliffe AM, Chilvers ER, Haslett C, Dransfield I. Priming differentially regulates neutrophil adhesion molecule expression/function. Immunology. 1996;89(1):105–111. doi:10.1046/j.1365-2567.1996.d01-711.x8911147
  • Tkacova R. Systemic inflammation in chronic obstructive pulmonary disease: may adipose tissue play a role? Review of the literature and future perspectives. Mediators Inflamm. 2010;2010:585989. doi:10.1155/2010/58598920414465
  • Vaitkus M, Lavinskiene S, Barkauskiene D, Bieksiene K, Jeroch J, Sakalauskas R. Reactive oxygen species in peripheral blood and sputum neutrophils during bacterial and nonbacterial acute exacerbation of chronic obstructive pulmonary disease. Inflammation. 2013;36(6):1485–1493. doi:10.1007/s10753-013-9690-323872721
  • Wouters EF, Reynaert NL, Dentener MA, Vernooy JH. Systemic and local inflammation in asthma and chronic obstructive pulmonary disease: is there a connection? Proc Am Thorac Soc. 2009;6(8):638–647. doi:10.1513/pats.200907-073DP20008867
  • Leliefeld PHC, Pillay J, Vrisekoop N, et al. Differential antibacterial control by neutrophil subsets. Blood Adv. 2018;2(11):1344–1355. doi:10.1182/bloodadvances.201701557829895625
  • Ekstedt S, Safholm J, Georen SK, Cardell LO. Dividing neutrophils in subsets reveals a significant role for activated neutrophils in the development of airway hyperreactivity. Clin Exp Allergy. 2019;49(3):285–291. doi:10.1111/cea.1331130415501