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ORIGINAL RESEARCH

Characterization of Hypervirulent and Carbapenem-Resistant K. pneumoniae Isolated from Neurological Patients

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Pages 403-411 | Received 21 Oct 2022, Accepted 16 Jan 2023, Published online: 24 Jan 2023

References

  • Lan P, Jiang Y, Zhou J, Yu Y. A global perspective on the convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniae. J Glob Antimicrob Resist. 2021;25:26–34. doi:10.1016/j.jgar.2021.02.020
  • Nordmann P, Cuzon G, Naas T. The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect Dis. 2009;9(4):228–236. doi:10.1016/S1473-3099(09)70054-4
  • Choby JE, Howard-Anderson J, Weiss DS. Hypervirulent Klebsiella pneumoniae - clinical and molecular perspectives. J Intern Med. 2020;287(3):283–300. doi:10.1111/joim.13007
  • Yang X, Dong N, Chan EW, Zhang R, Chen S. Carbapenem resistance-encoding and virulence-encoding conjugative plasmids in Klebsiella pneumoniae. Trends Microbiol. 2021;29(1):65–83. doi:10.1016/j.tim.2020.04.012
  • Tian D, Liu X, Chen W, et al. Prevalence of hypervirulent and carbapenem-resistant Klebsiella pneumoniae under divergent evolutionary patterns. Emerg Microbes Infect. 2022;11(1):1936–1949. doi:10.1080/22221751.2022.2103454
  • Bialek-Davenet S, Criscuolo A, Ailloud F, et al. Genomic definition of hypervirulent and multidrug-resistant Klebsiella pneumoniae clonal groups. Emerg Infect Dis. 2014;20(11):1812–1820. doi:10.3201/eid2011.140206
  • Gu D, Dong N, Zheng Z, et al. A fatal outbreak of st11 carbapenem-resistant hypervirulent Klebsiella pneumoniae in a Chinese hospital: a molecular epidemiological study. Lancet Infect Dis. 2018;18(1):37–46. doi:10.1016/S1473-3099(17)30489-9
  • Zhao Y, Zhang X, Torres V, et al. An outbreak of carbapenem-resistant and hypervirulent Klebsiella pneumoniae in an intensive care unit of a major teaching hospital in Wenzhou, China. Front Public Health. 2019;7:229. doi:10.3389/fpubh.2019.00229
  • Siu LK, Yeh KM, Lin JC, Fung CP, Chang FY. Klebsiella pneumoniae liver abscess: a new invasive syndrome. Lancet Infect Dis. 2012;12(11):881–887. doi:10.1016/S1473-3099(12)70205-0
  • Lederman ER, Crum NF. Pyogenic liver abscess with a focus on Klebsiella pneumoniae as a primary pathogen: an emerging disease with unique clinical characteristics. Am J Gastroenterol. 2005;100(2):322–331. doi:10.1111/j.1572-0241.2005.40310.x
  • Fang CT, Lai SY, Yi WC, Hsueh PR, Liu KL, Chang SC. Klebsiella pneumoniae genotype k1: an emerging pathogen that causes septic ocular or central nervous system complications from pyogenic liver abscess. Clin Infect Dis. 2007;45(3):284–293. doi:10.1086/519262
  • Patel PK, Russo TA, Karchmer AW. Hypervirulent Klebsiella pneumoniae. Open Forum Infect Dis. 2014;1(1):ofu028. doi:10.1093/ofid/ofu028
  • Saccente M. Klebsiella pneumoniae liver abscess, endophthalmitis, and meningitis in a man with newly recognized diabetes mellitus. Clin Infect Dis. 1999;29(6):1570–1571. doi:10.1086/313539
  • Kuramochi G, Takei SI, Sato M, Isokawa O, Takemae T, Takahashi A. Klebsiella pneumoniae liver abscess associated with septic spinal epidural abscess. Hepatol Res. 2005;31(1):48–52. doi:10.1016/j.hepres.2004.09.006
  • CLSI. Performance standards for antimicrobial susceptibility testing. In: Clinical and Laboratory Standards Institute. Wayne, PA: CLSI; 2022:M100–M128.
  • Zhou Y, Ai W, Cao Y, et al. The co-occurrence of ndm-5, mcr-1, and fosa3-encoding plasmids contributed to the generation of extensively drug-resistant Klebsiella pneumoniae. Front Microbiol. 2022;12. doi:10.3389/fmicb.2021.811263
  • Tian D, Wang W, Li M, et al. Acquisition of the conjugative virulence plasmid from a cg23 hypervirulent Klebsiella pneumoniae strain enhances bacterial virulence. Front Cell Infect Microbiol. 2021;11:752011. doi:10.3389/fcimb.2021.752011
  • Hughes C, Phillips R, Roberts AP. Serum resistance among Escherichia coli strains causing urinary tract infection in relation to o type and the carriage of hemolysin, colicin, and antibiotic resistance determinants. Infect Immun. 1982;35(1):270–275. doi:10.1128/iai.35.1.270-275.1982
  • Wang M, Earley M, Chen L, et al. Clinical outcomes and bacterial characteristics of carbapenem-resistant Klebsiella pneumoniae complex among patients from different global regions (crackle-2): a prospective, multicentre, cohort study. Lancet Infect Dis. 2021;22:401–412. doi:10.1016/S1473-3099(21)00399-6
  • Lam M, Wick RR, Wyres KL, et al. Genetic diversity, mobilisation and spread of the yersiniabactin-encoding mobile element icekp in Klebsiella pneumoniae populations. Microb Genom. 2018;4(9). doi:10.1099/mgen.0.000196
  • Chen L, Mathema B, Chavda KD, Deleo FR, Bonomo RA, Kreiswirth BN. Carbapenemase-producing Klebsiella pneumoniae: molecular and genetic decoding. Trends Microbiol. 2014;22(12):686–696. doi:10.1016/j.tim.2014.09.003
  • Fu P, Tang Y, Li G, Yu L, Wang Y, Jiang X. Pandemic spread of bla((kpc-2)) among Klebsiella pneumoniae st11 in China is associated with horizontal transfer mediated by incfii-like plasmids. Int J Antimicrob Agents. 2019;54(2):117–124. doi:10.1016/j.ijantimicag.2019.03.014
  • Tian D, Wang M, Zhou Y, Hu D, Ou HY, Jiang X. Genetic diversity and evolution of the virulence plasmids encoding aerobactin and salmochelin in Klebsiella pneumoniae. Virulence. 2021;12(1):1323–1333. doi:10.1080/21505594.2021.1924019
  • Xu Y, Zhang J, Wang M, et al. Mobilization of the nonconjugative virulence plasmid from hypervirulent Klebsiella pneumoniae. Genome Med. 2021;13(1):119. doi:10.1186/s13073-021-00936-5
  • Cienfuegos-Gallet AV, Zhou Y, Ai W, Kreiswirth BN, Yu F, Chen L. Multicenter genomic analysis of carbapenem-resistant Klebsiella pneumoniae from bacteremia in China. Microbiol Spectr. 2022;10(2). doi:10.1128/spectrum.02290-21
  • Lin TL, Lee CZ, Hsieh PF, Tsai SF, Wang JT. Characterization of integrative and conjugative element icekp1-associated genomic heterogeneity in a Klebsiella pneumoniae strain isolated from a primary liver abscess. J Bacteriol. 2008;190(2):515–526. doi:10.1128/JB.01219-07
  • Zhou K, Xiao T, David S, et al. Novel subclone of carbapenem-resistant Klebsiella pneumoniae sequence type 11 with enhanced virulence and transmissibility, China. Emerg Infect Dis. 2020;26(2):289–297. doi:10.3201/eid2602.190594