228
Views
4
CrossRef citations to date
0
Altmetric
REVIEW

Safety and Efficacy of COVID-19 Vaccine in Africa: Systematic Review

& ORCID Icon
Pages 3085-3100 | Received 28 Jan 2023, Accepted 06 May 2023, Published online: 18 May 2023

References

  • Vivekanandhan K, Shanmugam P, Barabadi H, et al. Emerging therapeutic approaches to combat COVID-19: present status and future perspectives. Front Mol Biosci. 2021;8:604447. doi:10.3389/fmolb.2021.604447
  • Choi EM. COVID-19 vaccines for low-and middle-income countries. Trans R Soc Trop Med Hyg. 2021;115(5):447–456. doi:10.1093/trstmh/trab045
  • Rauf A, Abu-Izneid T, Olatunde A, et al. COVID-19 pandemic: epidemiology, etiology, conventional and non-conventional therapies. Int J Environ Res Public Health. 2020;17(21):8155. doi:10.3390/ijerph17218155
  • Worldometer. COVID-19 Coronavirus Pandemic; 2022. Available from: https://www.worldometers.info/coronavirus/. Accessed October 21, 2022.
  • Wiysonge CS, Ndwandwe D, Mathebula L, Goga A, Gray G. Randomised trials of COVID-19 vaccines in Africa-charting the path forward. S Afr J Sci. 2022;118(5–6):1–4. doi:10.17159/sajs.2022/13224
  • Jethwa H, Wong R, Abraham S. Covid-19 vaccine trials: ethnic diversity and immunogenicity. Vaccine. 2021;39(27):3541. doi:10.1016/j.vaccine.2021.05.017
  • Acosta-Coley I, Cervantes-Ceballos L, Tejeda-Benítez L, et al. Vaccines platforms and COVID-19: what you need to know. Trop Dis Travel Med Vaccines. 2022;8(1):1–19. doi:10.1186/s40794-022-00176-4
  • AfricaCDC.org. Africa CDC COVID-19 Vaccine Dashboard. Addis Ababa: Africa Centres for Disease Control and Prevention; 2022. Available from: https://africacdc.org/covid-19-vaccination/. Accessed October 30, 2022.
  • Yepes-Nuñez J, Urrutia G, Romero-Garcia M, Alonso-Fernandez S. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. Revista Espanola de Cardiolog. 2021;74(9):790–799.
  • Page MJ, McKenzie JE, Bossuyt PM et al . (2021). The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ, n71 10.1136/bmj.n71
  • Zhang Y, Belayachi J, Yang Y, et al. Real-world study of the effectiveness of BBIBP-CorV (Sinopharm) COVID-19 vaccine in the Kingdom of Morocco. medRxiv. 2022;22:1584.
  • Hammad NM, Kadry HM, Malek MM, et al. Maintenance of antibody response in Egyptian healthcare workers vaccinated with ChAdOx1 nCoV-19 vaccine during delta and omicron variants pandemic: a prospective study. Vaccines. 2022;10(10):1706. doi:10.3390/vaccines10101706
  • Takuva S, Takalani A, Seocharan I, et al. Safety evaluation of the single-dose Ad26. COV2. S vaccine among healthcare workers in the Sisonke study in South Africa: a Phase 3b implementation trial. PLoS Med. 2022;19(6):e1004024. doi:10.1371/journal.pmed.1004024
  • Gray G, Collie S, Goga A, et al. Effectiveness of Ad26. COV2. S and BNT162b2 vaccines against Omicron variant in South Africa. N Engl J Med. 2022;386:2243–2245. doi:10.1056/NEJMc2202061
  • Thomas SJ, Moreira ED, Kitchin N, et al. Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine through 6 months. N Engl J Med. 2021;385(19):1761–1773. doi:10.1056/NEJMoa2110345
  • Moreira ED, Kitchin N, Xu X, et al. Safety and efficacy of a third dose of BNT162b2 COVID-19 vaccine. N Engl J Med. 2022;386(20):1910–1921. doi:10.1056/NEJMoa2200674
  • Sadoff J, Gray G, Vandebosch A, et al. Final analysis of efficacy and safety of single-dose Ad26. COV2. S. N Engl J Med. 2022;386(9):847–860. doi:10.1056/NEJMoa2117608
  • Bekker L-G, Garrett N, Goga A, et al. Effectiveness of the Ad26. COV2. S vaccine in health-care workers in South Africa (the Sisonke study): results from a single-arm, open-label, phase 3B, implementation study. Lancet. 2022;399(10330):1141–1153. doi:10.1016/S0140-6736(22)00007-1
  • Hardt K, Vandebosch A, Sadoff J, et al. Efficacy, safety, and immunogenicity of a booster regimen of Ad26. COV2. S vaccine against COVID-19 (ENSEMBLE2): results of a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Infect Dis. 2022;22:1703–1715. doi:10.1016/S1473-3099(22)00506-0
  • Madhi SA, Moodley D, Hanley S, et al. Immunogenicity and safety of a SARS-CoV-2 recombinant spike protein nanoparticle vaccine in people living with and without HIV-1 infection: a randomised, controlled, Phase 2A/2B trial. Lancet HIV. 2022;9(5):e309–e322. doi:10.1016/S2352-3018(22)00041-8
  • Madhi SA, Koen AL, Izu A, et al. Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 in people living with and without HIV in South Africa: an interim analysis of a randomised, double-blind, placebo-controlled, phase 1B/2A trial. Lancet HIV. 2021;8(9):e568–e580. doi:10.1016/S2352-3018(21)00157-0
  • Madhi SA, Baillie V, Cutland CL, et al. Efficacy of the ChAdOx1 nCoV-19 Covid-19 vaccine against the B. 1.351 variant. N Engl J Med. 2021;384(20):1885–1898. doi:10.1056/NEJMoa2102214
  • Mellet J, Pepper MS. A COVID-19 vaccine: big strides come with big challenges. Vaccines. 2021;9(1):39. doi:10.3390/vaccines9010039
  • Ndwandwe D, Dube K, Mathebula L, Wiysonge CS. Description of vaccine clinical trials in Africa: a narrative review. Hum Vaccin Immunother. 2020;16(4):972–980. doi:10.1080/21645515.2019.1693720
  • WHO. Vaccine efficacy, effectiveness and protection; 2021. Available from: https://www.who.int/news-room/feature-stories/detail/vaccine-efficacy-effectiveness-and-protection. Accessed October 30, 2022.
  • Han X, Xu P, Ye Q. Analysis of COVID‐19 vaccines: types, thoughts, and application. J Clin Lab Anal. 2021;35(9):e23937. doi:10.1002/jcla.23937
  • Pormohammad A, Zarei M, Ghorbani S, et al. Efficacy and safety of COVID-19 vaccines: a systematic review and meta-analysis of randomized clinical trials. Vaccines. 2021;9(5):467. doi:10.3390/vaccines9050467
  • Bravo L, Smolenov I, Han HH, et al. Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial. Lancet. 2022;399(10323):461–472. doi:10.1016/S0140-6736(22)00055-1
  • Shinde V, Bhikha S, Hoosain Z, et al. Efficacy of NVX-CoV2373 Covid-19 vaccine against the B. 1.351 variant. N Engl J Med. 2021;384(20):1899–1909. doi:10.1056/NEJMoa2103055
  • Rumpa Saha AR, Dewan P, Nirmal K, et al. Antibody response to SARS-CoV-2 in HIV patients co-infected with COVID-19. Int J Virol AIDS. 2021;8(2):154.
  • Lombardi F, Ricci R, Belmonti S, et al. Seroprevalence of SARS-CoV-2 antibodies in HIV-infected patients in Rome, Italy during the COVID-19 outbreak. Diagnostics. 2021;11(7):1154. doi:10.3390/diagnostics11071154
  • Lomte TS. Higher contact among vaccinated people may negatively influence vaccine effectiveness. Med Sci News. 2022;2022:154.
  • Corinne Danet FF. Management of a measles epidemic. 2022.
  • Nadeem I, Ul Munamm SA, Rasool MU, et al. Safety and efficacy of Sinopharm vaccine (BBIBP-CorV) in elderly population of Faisalabad district of Pakistan. Postgrad Med J. 2022;postgradmedj-2022–141649. doi:10.1136/postgradmedj-2022-141649
  • WHO. Vaccine safety basics; 2022. Available from: https://openwho.org/courses/vaccine-safety-basics. Accessed October 30, 2022.
  • Bodner K, Knight J, Hamilton MA, Mishra S. Higher contact among vaccinated can be a mechanism for negative vaccine effectiveness. 2022.