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ORIGINAL RESEARCH

Drug Susceptibility Test and Analysis of Quinolone Resistance Genes in Mycoplasma hyopneumoniae Vaccine Strains and Field Isolates from China

ORCID Icon & ORCID Icon
Pages 2075-2087 | Received 07 Feb 2023, Accepted 01 Apr 2023, Published online: 08 Apr 2023

References

  • Thongkamkoon P, Narongsak W, Kobayashi H, et al. In Vitro Susceptibility of Mycoplasma hyopneumoniae Field Isolates and Occurrence of Fluoroquinolone, Macrolides and Lincomycin Resistance. J Vet Med Sci. 2013;75(8):1067–1070. doi:10.1292/jvms.12-0520
  • Beylefeld A, Wambulawaye P, Bwala DG, et al. Evidence for Multidrug Resistance in Nonpathogenic Mycoplasma Species Isolated from South African Poultry. Appl Environ Microbiol. 2018;84(21):e01660–18. doi:10.1128/AEM.01660-18
  • Hata E, Harada T, Itoh M. Relationship between Antimicrobial Susceptibility and Multilocus Sequence Type of Mycoplasma bovis Isolates and Development of a Method for Rapid Detection of Point Mutations Involved in Decreased Susceptibility to Macrolides, Lincosamides, Tetracyclines, and Spectinomycin. Appl Environ Microbiol. 2019;85(13):e00575–19. doi:10.1128/AEM.00575-19
  • World Organisation for Animal Health (OIE). Terrestrial Animal Health Code; 2021.
  • Haulisah NA, Hassan L, Bejo SK, et al. High Levels of Antibiotic Resistance in Isolates From Diseased Livestock. Front Vet Sci. 2021;8:652351. doi:10.3389/fvets.2021.652351
  • Felde O, Kreizinger Z, Sulyok KM, et al. Antibiotic susceptibility testing of Mycoplasma hyopneumoniae field isolates from Central Europe for fifteen antibiotics by microbroth dilution method. PLoS One. 2018;13(12). doi:10.1371/journal.pone.0209030.
  • Yang L, Yingbo S, Junyao J, et al. Distinct Increase in Antimicrobial Resistance Genes among Escherichia Coli During 50 Years of Antimicrobial Use in Livestock Production in China. Nature Food. 2022;3(3):197–205. doi:10.1038/s43016-022-00470-6
  • Gautier-Bouchardon AV, Ferre´ S, Le Grand D, et al. Overall Decrease in the Susceptibility of Mycoplasma bovis to Antimicrobials over the Past 30 Years in France. PLoS One. 2014;9(2):e87672. doi:10.1371/journal.pone.0087672
  • Qiu G, Rui Y, Li K, et al. Detection and phylogenetic analysis of Mycoplasma hyopneumoniae from Tibetan pigs in western China. Trop Anim Health Prod. 2017;49:1545–1551. doi:10.1007/s11250-017-1365-x
  • Haumaier F, Schneider-Fuchs A, Backert S, et al. Rapid Detection of Quinolone Resistance Mutations in gyrA of Helicobacter pylori by Real-Time PCR. Pathogens. 2022;11:59. doi:10.3390/pathogens11010059
  • Sharratt M, Sands K, Portal Edward AR, et al. Mycoplasma hominis Defining Fluoroquinolone Resistance-Mediating Mutations from Non-Resistance Polymorphisms in Topoisomerases. Antibiotics. 2021;10(11):1379. doi:10.3390/antibiotics10111379
  • Chen Z, Bai J, Zhang X, et al. Highly prevalent multidrug resistance and QRDR mutations in Salmonella isolated from chicken, pork and duck meat in Southern China, 2018-2019. Int J Food Microbiol. 2021;340:109055. doi:10.1016/j.ijfoodmicro.2021.109055
  • Herrera-Sánchez MP, Castro-Vargas RE, Fandiño-de-Rubio LC, et al. Molecular identification of fluoroquinolone resistance in Salmonella spp. isolated from broiler farms and human samples obtained from two regions in Colombia. Vet World. 2021;14(7):1767–1773. doi:10.14202/vetworld.2021.1767-1773
  • Kang JY, Lee W, Noh Gwang M, et al. Fluoroquinolone resistance of Staphylococcus epidermidis isolated from healthy conjunctiva and analysis of their mutations in quinolone-resistance determining region. Antimicrob Resist Infect Control. 2020;9(1):177. doi:10.1186/s13756-020-00841-3
  • Reinhardt AK, Bébéar CM, Kobisch M, et al. Characterization of mutations in DNA gyrase and topoisomerase IV Involved in quinolone resistance of Mycoplasma gallisepticum mutants obtained in vitro. Antimicrob Agents Chemother. 2002;46(2):590–593. doi:10.1128/AAC.46.2.590-593.2002
  • Le Carrou J, Laurentie M, Kobisch M, et al. Persistence of Mycoplasma hyopneumoniae in experimentally infected pigs after marbofloxacin treatment and detection of mutations in the parC gene. Antimicrob Agents Chemother. 2006;50(6):1959–1966. doi:10.1128/AAC.01527-05
  • Yongyan L, Xin L, Xiansheng N, et al. High Carriage Rate of the Multiple Resistant Plasmids Harboring Quinolone Resistance Genes in Enterobacter spp.Isolated from Healthy Individuals. Antibiotics. 2021;11(15):1101–1115.
  • Raherison S, Gonzalez P, Renaudin H, et al. Evidence of active efflux in resistance to ciprofloxacin and to ethidium bromide by Mycoplasma hominis. Antimicrob Agents Chemother. 2002;46:672–679. doi:10.1128/AAC.46.3.672-679.2002
  • Gong X, Ma W, Chen Q, et al. Research progress on drug resistance and drug resistance mechanism of Mycoplasma in livestock and poultry.China. Anim Husb and Vet Med. 2017;44(08):2489–2495.
  • Hannan PC. Guidelines and recommendations for antimicrobial minimum inhibitory concentration (MIC) testing against veterinary mycoplasma species. International Research Programme on Comparative Mycoplasmology. Vet Res. 2000;31(4):373–395. doi:10.1051/vetres:2000100
  • Gautier-Bouchardon AV. Antimicrobial Resistance in Mycoplasma spp. Microbiol Spectr. 2018;6(4):21. doi:10.1128/microbiolspec.ARBA-0030-2018
  • Satlin Michael J, Lewis James S, Weinstein Melvin P, et al. Clinical and Laboratory Standards Institute and European Committee on Antimicrobial Susceptibility Testing Position Statements on Polymyxin B and Colistin Clinical Breakpoints. Clin Infect Dis. 2020;71(9):e523–e529. doi:10.1093/cid/ciaa121
  • Turnidge J, Sei K, Mouton J. Polymyxin Susceptibility Testing and Breakpoint Setting. Adv Exp Med Biol. 2019;1145:117–132.
  • Espinel IA, Turnidge J, Alastruey IA, et al. Cyp51APosaconazole MIC Distributions for Aspergillus fumigatus Species Complex by Four Methods: impact of Mutations on Estimation of Epidemiological Cutoff Values. Antimicrob Agents Chemother. 2018;62(4):e01916–17.
  • Bokma J, Gille L, De Bleecker K, et al. Antimicrobial Susceptibility of Mycoplasma bovis Isolates from Veal, Dairy and Beef Herds. Antibiotics. 2020;9(12):882. doi:10.3390/antibiotics9120882
  • Bokma J, Vereecke N, Nauwynck H, et al. Genome-wide association study reveals genetic markers for antimicrobial resistance in Mycoplasma bovis. Microbiol Spectr. 2021;9:e00262–21. doi:10.1128/Spectrum.00262-21
  • Ana E-I, John T. The role of epidemiological cut-off values (ECVs/ECOFFs) in antifungal susceptibility testing and interpretation for uncommon yeasts and moulds. Rev Iberoam Micol. 2016;33(2):63–75. doi:10.1016/j.riam.2016.04.001
  • Qiu G, Rui Y, Yi B, et al. Identification and Genomic Analysis of a Pathogenic Strain of Mycoplasma hyopneumoniae(TB1) isolated from Tibetan Pigs. DNA Cell Biol. 2019;38(9):922–932. doi:10.1089/dna.2018.4560
  • CLSI. Performance Standards for Antimicrobial Susceptibility Testing. 33rd ed. PA: Clinical and Laboratory Standards Institute; 2022.
  • Le Carrou J, Laurentie M, Kobisch M, et al. Persistence of Mycoplasma hyopneumoniae in experimentally infected pigs after marbofloxacin treatment and detection of mutations in the parC gene. Antimicrob Agents Chemother. 2006;50(6):1959–1966.
  • Felde O, Kreizinger Z, Sulyok KM, et al. Antibiotic susceptibility testing of Mycoplasma hyopneumoniae field isolates from Central Europe for fifteen antibiotics by microbroth dilution method. PLoS One. 2018;13(12):209–230.
  • Gonzaga NF, De Souza LFL, et al. Antimicrobial susceptibility and genetic profile of Mycoplasma hyopneumoniae isolates from Brazil. Braz J of Microbiol. 2020;51(1):377–384. doi:10.1007/s42770-019-00185-0
  • Huang ZL, Mao CX, Wei YZ, et al. Analysis of the mutant selection window and killing of Mycoplasma hyopneumoniae for doxycycline, tylosin, danofloxacin, tiamulin and valnemulin. PLoS One. 2020;15(6):220–350.
  • Klein U, De Jong A, Moyaert H, et al. Antimicrobial susceptibility monitoring of Mycoplasma hyopneumoniae and Mycoplasma bovis isolated in Europe. Vet Microbiol. 2017;204:188–193. doi:10.1016/j.vetmic.2017.04.012
  • Tavio MM, Poveda C, Assuncao P, et al. In vitro activity of tylvalosin against Spanish field strains of Mycoplasma hyopneumoniae. Vet Rec. 2014;175(21):538–U568. doi:10.1136/vr.102458
  • De Jong A, Youala M, Klein U, et al. Antimicrobial susceptibility monitoring of Mycoplasma hyopneumoniae isolated from seven European countries during 2015-2016. Vet Microbiol. 2021:1;253.
  • Wang Z, Xu Y, Zhu W, et al. Investigation and drug resistance analysis of prevalent strains of Haemophilus parasuis. Chinese J of Vet Med. 2019;39(10):1942–1946.
  • Huiling Q, Fu C. Observation on the therapeutic effect of tilmicosin and tylosin on Mycoplasma suis pneumonia. Anim Hus and Vet Med. 2009;41(11):69–71.
  • Zhang C, Shen Q, Hu H, et al. In vitro antibacterial drug sensitivity test of Mycoplasma hyopneumoniae. Chinese J of Vet Drugs. 2013;47:10–12.
  • Wei L, Shaobo X, Mao L, et al. Comparative genomic analyses of Mycoplasma hyopneumoniae pathogenic 168 strain and its high-passaged attenuated strain. BMC Genomics. 2013;14:80. doi:10.1186/1471-2164-14-80
  • Kuo HC, Chou CC, Chang CD, et al. Characterization of quinolone resistant enterococcus faecalis isolates from healthy chickens and pigs in Taiwan. J of Food and Drug Anal. 2009;17(6):2.
  • Lysnyansky I, Gerchman I, Mikula I, et al. Molecular Characterization of Acquired enrofloxacin Resistance in Mycoplasma synoviae Field Isolates. Antimicrob Agents Chemother. 2013;57(7):3072–3077. doi:10.1128/AAC.00203-13
  • Vicca J, Maes D, Stakenborg T, et al. Resistance mechanism against fluoroquinolones in mycoplasma hyopneumoniae field isolates. Microb Drug Resist. 2007;13(3):166–170. doi:10.1089/mdr.2007.716
  • Zhang XR, Guo MJ, Xie D, et al. Antibiotic resistance of Mycoplasma Synoviae strains isolated in China from 2016 to 2019. BMC Vet Res. 2022;18(1):021–031. doi:10.1186/s12917-021-03104-4
  • Shedko ED, Khayrullina GA, Goloveshkina EN, et al. Clinical evaluation of commercial PCR assays for antimicrobial resistance in Mycoplasma genitalium and estimation of resistance-mediated mutation prevalence in Moscow and Moscow region. Euro J of Clin Microbi & Infe Dise. 2021;40(7):1413–1418. doi:10.1007/s10096-021-04170-0
  • Garcia GA, Nouvel LX, Baranowski E, et al. Mycoplasma bovis in Spanish Cattle Herds: two Groups of Multiresistant isolates Predominate, with One Remaining Susceptible to Fluoroquinolones. Pathogens. 2020;9(7):705–745. doi:10.3390/pathogens9090705
  • Stakenborg T, Vicca J, Butaye P, et al. Characterization of In Vivo acquired resistance of Mycoplasma hyopneumoniae to macrolides and lincosamides. Microb Drug Resist. 2005;11(3):290–294. doi:10.1089/mdr.2005.11.290
  • Qiu G, Rui Y, Zhang J, et al. Macrolide-Resistance Selection in Tibetan Pigs with a High Load of Mycoplasma hyopneumoniae. Microb Drug Resist. 2018;24(7):1043–1049. doi:10.1089/mdr.2017.0254