Attenuated Cytokine-Induced Memory-Like Natural Killer Cell Responses to Mycobacterium tuberculosis in Tuberculosis Patients

References

• World Health Organization. Global Tuberculosis Report 2022. Geneva: World Health Organization; 2022.
   Google Scholar
• Shi YH, Zhu SW, Mao XZ, et al. Transcriptome profiling, molecular biological, and physiological studies reveal a major role for ethylene in cotton fiber cell elongation. Plant Cell. 2006;18(3):651–664. doi:10.1105/tpc.105.040303
   PubMed Web of Science ®Google Scholar
• Harding E. WHO global progress report on tuberculosis elimination. Lancet Respir Med. 2020;8(1):19. doi:10.1016/S2213-2600(19)30418-7
   PubMed Web of Science ®Google Scholar
• Russell DG, VanderVen BC, Lee W, et al. Mycobacterium tuberculosis wears what it eats. Cell Host Microbe. 2010;8(1):68–76. doi:10.1016/j.chom.2010.06.002
   PubMed Web of Science ®Google Scholar
• Shah M, Dorman SE. Latent tuberculosis infection. N Engl J Med. 2021;385(24):2271–2280. doi:10.1056/NEJMcp2108501
   PubMed Web of Science ®Google Scholar
• Gengenbacher M, Kaufmann SH. Mycobacterium tuberculosis: success through dormancy. FEMS Microbiol Rev. 2012;36(3):514–532. doi:10.1111/j.1574-6976.2012.00331.x
   PubMed Web of Science ®Google Scholar
• Liu CH, Liu H, Ge B. Innate immunity in tuberculosis: host defense vs pathogen evasion. Cell Mol Immunol. 2017;14(12):963–975. doi:10.1038/cmi.2017.88
   PubMed Web of Science ®Google Scholar
• Maroof A, Beattie L, Zubairi S, Svensson M, Stager S, Kaye PM. Posttranscriptional regulation of II10 gene expression allows natural killer cells to express immunoregulatory function. Immunity. 2008;29(2):295–305. doi:10.1016/j.immuni.2008.06.012
   PubMed Web of Science ®Google Scholar
• Bozzano F, Costa P, Passalacqua G, et al. Functionally relevant decreases in activatory receptor expression on NK cells are associated with pulmonary tuberculosis in vivo and persist after successful treatment. Int Immunol. 2009;21(7):779–791. doi:10.1093/intimm/dxp046
   PubMed Web of Science ®Google Scholar
• Ratcliffe LT, Lukey PT, MacKenzie CR, Ress SR. Reduced NK activity correlates with active disease in HIV- patients with multidrug-resistant pulmonary tuberculosis. Clin Exp Immunol. 1994;97(3):373–379. doi:10.1111/j.1365-2249.1994.tb06097.x
   PubMed Web of Science ®Google Scholar
• Esin S, Batoni G. Natural killer cells: a coherent model for their functional role in Mycobacterium tuberculosis infection. J Innate Immun. 2015;7(1):11–24. doi:10.1159/000363321
   PubMed Web of Science ®Google Scholar
• Lodoen MB, Lanier LL. Natural killer cells as an initial defense against pathogens. Curr Opin Immunol. 2006;18(4):391–398. doi:10.1016/j.coi.2006.05.002
   PubMed Web of Science ®Google Scholar
• Erkes DA, Selvan SR. Hapten-induced contact hypersensitivity, autoimmune reactions, and tumor regression: plausibility of mediating antitumor immunity. J Immunol Res. 2014;2014:175265. doi:10.1155/2014/175265
   PubMed Web of Science ®Google Scholar
• Terren I, Orrantia A, Astarloa-Pando G, Amarilla-Irusta A, Zenarruzabeitia O, Borrego F. Cytokine-induced memory-like NK cells: from the basics to clinical applications. Front Immunol. 2022;13:884648. doi:10.3389/fimmu.2022.884648
   PubMed Web of Science ®Google Scholar
• Sun JC, Beilke JN, Lanier LL. Adaptive immune features of natural killer cells. Nature. 2009;457(7229):557–561. doi:10.1038/nature07665
   PubMed Web of Science ®Google Scholar
• Abdul-Careem MF, Lee AJ, Pek EA, et al. Genital HSV-2 infection induces short-term NK cell memory. PLoS One. 2012;7(3):e32821. doi:10.1371/journal.pone.0032821
   PubMed Web of Science ®Google Scholar
• Paust S, Gill HS, Wang BZ, et al. Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses. Nat Immunol. 2010;11(12):1127–1135. doi:10.1038/ni.1953
   PubMed Web of Science ®Google Scholar
• Reeves RK, Li H, Jost S, et al. Antigen-specific NK cell memory in rhesus macaques. Nat Immunol. 2015;16(9):927–932. doi:10.1038/ni.3227
   PubMed Web of Science ®Google Scholar
• Habib S, El Andaloussi A, Hisham A, Ismail N, Cell-Mediated NK. Regulation of protective memory responses against intracellular ehrlichial pathogens. PLoS One. 2016;11(4):e0153223. doi:10.1371/journal.pone.0153223
   PubMed Web of Science ®Google Scholar
• Choreno Parra JA, Martinez Zuniga N, Jimenez Zamudio LA, Jimenez Alvarez LA, Salinas Lara C, Zuniga J. Memory of natural killer cells: a new chance against mycobacterium tuberculosis? Front Immunol. 2017;8:967. doi:10.3389/fimmu.2017.00967
   PubMed Web of Science ®Google Scholar
• Cooper MA, Elliott JM, Keyel PA, Yang L, Carrero JA, Yokoyama WM. Cytokine-induced memory-like natural killer cells. Proc Natl Acad Sci U S A. 2009;106(6):1915–1919. doi:10.1073/pnas.0813192106
   PubMed Web of Science ®Google Scholar
• Gang M, Wong P, Berrien-Elliott MM, Fehniger TA. Memory-like natural killer cells for cancer immunotherapy. Semin Hematol. 2020;57(4):185–193. doi:10.1053/j.seminhematol.2020.11.003
   PubMed Web of Science ®Google Scholar
• Braverman J, Sogi KM, Benjamin D, Nomura DK, Stanley SA. HIF-1alpha is an essential mediator of IFN-gamma-dependent immunity to mycobacterium tuberculosis. J Immunol. 2016;197(4):1287–1297. doi:10.4049/jimmunol.1600266
   PubMed Web of Science ®Google Scholar
• Romee R, Rosario M, Berrien-Elliott MM, et al. Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia. Sci Transl Med. 2016;8(357):357ra123. doi:10.1126/scitranslmed.aaf2341
   PubMed Web of Science ®Google Scholar
• Roy Chowdhury R, Vallania F, Yang Q, et al. A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes. Nature. 2018;560(7720):644–648. doi:10.1038/s41586-018-0439-x
   PubMed Web of Science ®Google Scholar
• Abebe F. Immunological basis of early clearance of Mycobacterium tuberculosis infection: the role of natural killer cells. Clin Exp Immunol. 2021;204(1):32–40. doi:10.1111/cei.13565
   PubMed Web of Science ®Google Scholar
• Kolloli A, Subbian S. Host-directed therapeutic strategies for tuberculosis. Front Med. 2017;4:171. doi:10.3389/fmed.2017.00171
   PubMed Web of Science ®Google Scholar
• Wallis RS, O’Garra A, Sher A, Wack A. Host-directed immunotherapy of viral and bacterial infections: past, present and future. Nat Rev Immunol. 2023;23(2):121–133. doi:10.1038/s41577-022-00734-z
   PubMed Web of Science ®Google Scholar
• Grzywacz B, Kataria N, Verneris MR. CD56(dim)CD16(+) NK cells downregulate CD16 following target cell induced activation of matrix metalloproteinases. Leukemia. 2007;21(2):356–359. doi:10.1038/sj.leu.2404499
   PubMed Web of Science ®Google Scholar
• Romee R, Foley B, Lenvik T, et al. NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17). Blood. 2013;121(18):3599–3608. doi:10.1182/blood-2012-04-425397
   PubMed Web of Science ®Google Scholar
• Schierloh P, Yokobori N, Aleman M, et al. Increased susceptibility to apoptosis of CD56dimCD16+ NK cells induces the enrichment of IFN-gamma-producing CD56bright cells in tuberculous pleurisy. J Immunol. 2005;175(10):6852–6860. doi:10.4049/jimmunol.175.10.6852
   PubMed Web of Science ®Google Scholar
• Rao D, Venkataswamy MM, Vasanthapuram R, Satishchandra P, Desai A. Alterations in natural killer and dendritic cell subsets in individuals with HIV-associated neurotuberculosis. J Med Virol. 2018;90(5):899–906. doi:10.1002/jmv.25042
   PubMed Web of Science ®Google Scholar
• Esaulova E, Das S, Singh DK, et al. The immune landscape in tuberculosis reveals populations linked to disease and latency. Cell Host Microbe. 2021;29(2):165–178 e8. doi:10.1016/j.chom.2020.11.013
   PubMed Web of Science ®Google Scholar
• Sherwood ER, Burelbach KR, McBride MA, et al. Innate immune memory and the host response to infection. J Immunol. 2022;208(4):785–792. doi:10.4049/jimmunol.2101058
   PubMed Web of Science ®Google Scholar
• Terren I, Orrantia A, Mosteiro A, Vitalle J, Zenarruzabeitia O, Borrego F. Metabolic changes of Interleukin-12/15/18-stimulated human NK cells. Sci Rep. 2021;11(1):6472. doi:10.1038/s41598-021-85960-6
   PubMed Web of Science ®Google Scholar
• Tarannum M, Romee R. Cytokine-induced memory-like natural killer cells for cancer immunotherapy. Stem Cell Res Ther. 2021;12(1):592. doi:10.1186/s13287-021-02655-5
   PubMed Web of Science ®Google Scholar
• Lopez-Verges S, Milush JM, Pandey S, et al. CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset. Blood. 2010;116(19):3865–3874. doi:10.1182/blood-2010-04-282301
   PubMed Web of Science ®Google Scholar
• Hazeldine J, Lord JM. The impact of ageing on natural killer cell function and potential consequences for health in older adults. Ageing Res Rev. 2013;12(4):1069–1078. doi:10.1016/j.arr.2013.04.003
   PubMed Web of Science ®Google Scholar
• Nielsen CM, White MJ, Goodier MR, Riley EM. Functional Significance of CD57 expression on human NK cells and relevance to disease. Front Immunol. 2013;4:422. doi:10.3389/fimmu.2013.00422
   PubMed Web of Science ®Google Scholar
• Garand M, Goodier M, Owolabi O, Donkor S, Kampmann B, Sutherland JS. Functional and phenotypic changes of natural killer cells in whole blood during mycobacterium tuberculosis infection and disease. Front Immunol. 2018;9:257. doi:10.3389/fimmu.2018.00257
   PubMedGoogle Scholar
• Di Vito C, Mikulak J, Mavilio D. On the way to become a natural killer cell. Front Immunol. 2019;10:1812. doi:10.3389/fimmu.2019.01812
   PubMedGoogle Scholar
• Albayrak N, Dirix V, Aerts L, et al. Differential expression of maturation and activation markers on NK cells in patients with active and latent tuberculosis. J Leukoc Biol. 2022;111(5):1031–1042. doi:10.1002/JLB.4A1020-641RR
   PubMed Web of Science ®Google Scholar
• Zhuang L, Fulton RJ, Rettman P, et al. Activity of IL-12/15/18 primed natural killer cells against hepatocellular carcinoma. Hepatol Int. 2019;13(1):75–83. doi:10.1007/s12072-018-9909-3
   PubMed Web of Science ®Google Scholar
• Condos R, Rom WN, Schluger NW. Treatment of multidrug-resistant pulmonary tuberculosis with interferon-gamma via aerosol. Lancet. 1997;349(9064):1513–1515. doi:10.1016/S0140-6736(96)12273-X
   PubMed Web of Science ®Google Scholar
• Raju B, Hoshino Y, Kuwabara K, et al. Aerosolized gamma interferon (IFN-gamma) induces expression of the genes encoding the IFN-gamma-inducible 10-kilodalton protein but not inducible nitric oxide synthase in the lung during tuberculosis. Infect Immun. 2004;72(3):1275–1283. doi:10.1128/IAI.72.3.1275-1283.2004
   PubMed Web of Science ®Google Scholar
• Ulrichs T, Kaufmann SH. New insights into the function of granulomas in human tuberculosis. J Pathol. 2006;208(2):261–269. doi:10.1002/path.1906
   PubMed Web of Science ®Google Scholar
• Schneider BE, Korbel D, Hagens K, et al. A role for IL-18 in protective immunity against Mycobacterium tuberculosis. Eur J Immunol. 2010;40(2):396–405. doi:10.1002/eji.200939583
   PubMed Web of Science ®Google Scholar
• Harris LD, Khayumbi J, Ongalo J, et al. Distinct human NK cell phenotypes and functional responses to mycobacterium tuberculosis in adults from TB endemic and non-endemic regions. Front Cell Infect Microbiol. 2020;10:120. doi:10.3389/fcimb.2020.00120
   PubMed Web of Science ®Google Scholar
• Vankayalapati R, Barnes PF. Innate and adaptive immune responses to human Mycobacterium tuberculosis infection. Tuberculosis. 2009;89(Suppl 1):S77–80. doi:10.1016/S1472-9792(09)70018-6
   PubMedGoogle Scholar
• Howard NC, Khader SA. Immunometabolism during Mycobacterium tuberculosis Infection. Trends Microbiol. 2020;28(10):832–850. doi:10.1016/j.tim.2020.04.010
   PubMed Web of Science ®Google Scholar
• Rao Y, Gai X, Le Y, et al. Enhanced Proinflammatory Cytokine Production and Immunometabolic Impairment of NK Cells Exposed to Mycobacterium tuberculosis and Cigarette Smoke. Front Cell Infect Microbiol. 2021;11:799276. doi:10.3389/fcimb.2021.799276
   PubMed Web of Science ®Google Scholar
• Kust SA, Streltsova MA, Panteleev AV, et al. HLA-DR-Positive NK cells expand in response to mycobacterium tuberculosis antigens and mediate mycobacteria-induced T cell activation. Front Immunol. 2021;12:662128. doi:10.3389/fimmu.2021.662128
   PubMedGoogle Scholar
• Jayaraman P, Jacques MK, Zhu C, et al. TIM3 mediates T cell exhaustion during mycobacterium tuberculosis infection. PLoS Pathog. 2016;12(3):e1005490. doi:10.1371/journal.ppat.1005490
   PubMed Web of Science ®Google Scholar
• Khan N, Vidyarthi A, Amir M, Mushtaq K, Agrewala JN. T-cell exhaustion in tuberculosis: pitfalls and prospects. Crit Rev Microbiol. 2017;43(2):133–141. doi:10.1080/1040841X.2016.1185603
   PubMed Web of Science ®Google Scholar
• Wondmagegn T, Damtie D, Genetu M, Biadgo B, Lemma M, Negash M. T lymphocyte subpopulations and intestinal helminthes profile among tuberculosis patients co-infected with HIV before and after anti tubercular treatment at university of Gondar hospital, Northwest Ethiopia. BMC Infect Dis. 2020;20(1):109. doi:10.1186/s12879-020-4845-y
   PubMed Web of Science ®Google Scholar
• Schafer JL, Muller-Trutwin MC, Reeves RK. NK cell exhaustion: bad news for chronic disease? Oncotarget. 2015;6(26):21797–21798. doi:10.18632/oncotarget.5490
   PubMedGoogle Scholar
• Netea MG, Quintin J, van der Meer JW. Trained immunity: a memory for innate host defense. Cell Host Microbe. 2011;9(5):355–361. doi:10.1016/j.chom.2011.04.006
   PubMed Web of Science ®Google Scholar
• Khader SA, Divangahi M, Hanekom W, et al. Targeting innate immunity for tuberculosis vaccination. J Clin Invest. 2019;129(9):3482–3491. doi:10.1172/JCI128877
   PubMed Web of Science ®Google Scholar
• Uppendahl LD, Felices M, Bendzick L, et al. Cytokine-induced memory-like natural killer cells have enhanced function, proliferation, and in vivo expansion against ovarian cancer cells. Gynecol Oncol. 2019;153(1):149–157. doi:10.1016/j.ygyno.2019.01.006
   PubMed Web of Science ®Google Scholar