Analysis of Metagenomic Next-Generation Sequencing (mNGS) in the Diagnosis of Herpes Simplex Virus (HSV) Encephalitis with Normal Cerebrospinal Fluid (CSF)

References

• Mancini M, Caignard G, Charbonneau B, et al. Rel-dependent immune and central nervous system mechanisms control viral replication and inflammation during mouse herpes simplex encephalitis. J Immunol. 2019;202(5):1479–1493. doi:10.4049/jimmunol.1800063
   PubMed Web of Science ®Google Scholar
• Zhang S-Y. Herpes simplex virus encephalitis of childhood: inborn errors of central nervous system cell-intrinsic immunity. Hum Genet. 2020;139(6):911–918. doi:10.1007/s00439-020-02127-5
   PubMed Web of Science ®Google Scholar
• Hodgson J, Zuckerman M, Smith M. Development of a novel internal control for a real-time PCR for HSV DNA types 1 and 2. J Clin Virol. 2007;38(3):217–220. doi:10.1016/j.jcv.2006.12.014
   PubMed Web of Science ®Google Scholar
• Steiner I, Benninger F. Manifestations of herpes virus infections in the nervous system. Neurol Clin. 2018;36(4):725–738. doi:10.1016/j.ncl.2018.06.005
   PubMed Web of Science ®Google Scholar
• Gnann JW, Whitley RJ. Herpes simplex encephalitis: an update. Curr Infect Dis Rep. 2017;19(3):1–12. doi:10.1007/s11908-017-0568-7
   PubMed Web of Science ®Google Scholar
• Simner PJ, Miller S, Carroll KC. Understanding the promises and hurdles of metagenomic next-generation sequencing as a diagnostic tool for infectious diseases. Clin Infect Dis. 2018;66(5):778–788. doi:10.1093/cid/cix881
   PubMed Web of Science ®Google Scholar
• Hogan CA, Yang S, Garner OB, et al. Clinical impact of metagenomic next-generation sequencing of plasma cell-free DNA for the diagnosis of infectious diseases: a multicenter retrospective cohort study. Clin Infect Dis. 2021;72(2):239–245. doi:10.1093/cid/ciaa035
   PubMed Web of Science ®Google Scholar
• Guan H, Shen A, Lv X, et al. Detection of virus in CSF from the cases with meningoencephalitis by next-generation sequencing. J Neurovirol. 2016;22(2):240–245. doi:10.1007/s13365-015-0390-7
   PubMed Web of Science ®Google Scholar
• Jakob L, Metzler G, Chen K-M, Garbe C. Non-AIDS associated Kaposi’s sarcoma: clinical features and treatment outcome. PLoS One. 2011;6(4):e18397. doi:10.1371/journal.pone.0018397
   PubMed Web of Science ®Google Scholar
• Avkan-Oguz V, Yapar N, Erdenizmenli M, et al. Effects of community-acquired infections on fever, leukocyte count and length of stay in the elderly. Saudi Med J. 2006;27(3):368–372.
   PubMed Web of Science ®Google Scholar
• Armangue T, Spatola M, Vlagea A, et al. Frequency, symptoms, risk factors, and outcomes of autoimmune encephalitis after herpes simplex encephalitis: a prospective observational study and retrospective analysis. Lancet Neurol. 2018;17(9):760–772. doi:10.1016/S1474-4422(18)30244-8
   PubMed Web of Science ®Google Scholar
• Levitz RE. Herpes simplex encephalitis: a review. Heart Lung. 1998;27(3):209–212. doi:10.1016/S0147-9563(98)90009-7
   PubMed Web of Science ®Google Scholar
• Whitley RJ. Viral encephalitis. N Engl J Med. 1990;323(4):242–250. doi:10.1056/NEJM199007263230406
   PubMed Web of Science ®Google Scholar
• Jaquet P, De Montmollin E, Dupuis C, et al. Functional outcomes in adult patients with herpes simplex encephalitis admitted to the ICU: a multicenter cohort study. Intensive Care Med. 2019;45(8):1103–1111. doi:10.1007/s00134-019-05684-0
   PubMed Web of Science ®Google Scholar
• Kapadia RK, Tyler KL, Pastula DM. Encephalitis in adults caused by herpes simplex virus. CMAJ. 2020;192(32):E919–E919. doi:10.1503/cmaj.191636
   PubMed Web of Science ®Google Scholar
• Yapar N, Sezak N, Cavuş A, et al. Two cases of herpes encephalitis with normal cerebrospinal fluid findings. Mikrobiyol Bul. 2006;40(1–2):93–98.
   PubMedGoogle Scholar
• Hansen MA, Hasbun R. US hospitalizations and 60-day readmission rates associated with herpes simplex virus encephalitis: analysis of all cause readmissions and encephalopathy associated readmissions. Clin Infect Dis. 2022;74(7):1174–1182. doi:10.1093/cid/ciab613
   PubMed Web of Science ®Google Scholar
• Studahl M, Lindquist L, Eriksson B-M, et al. Acute viral infections of the central nervous system in immunocompetent adults: diagnosis and management. Drugs. 2013;73(2):131–158. doi:10.1007/s40265-013-0007-5
   PubMed Web of Science ®Google Scholar
• Koskiniemi M, Piiparinen H, Mannonen L, Rantalaiho T, Vaheri A. Herpes encephalitis is a disease of middle aged and elderly people: polymerase chain reaction for detection of herpes simplex virus in the CSF of 516 patients with encephalitis. The Study Group. J Neurol Neurosurg Psychiatry. 1996;60(2):174–178. doi:10.1136/jnnp.60.2.174
   PubMed Web of Science ®Google Scholar
• Bewersdorf JP, Koedel U, Patzig M, et al. Challenges in HSV encephalitis: normocellular CSF, unremarkable CCT, and atypical MRI findings. Infection. 2019;47(2):267–273. doi:10.1007/s15010-018-1257-7
   PubMed Web of Science ®Google Scholar
• Stahl JP, Mailles A. Herpes simplex virus encephalitis update. Curr Opin Infect Dis. 2019;32(3):239–243. doi:10.1097/QCO.0000000000000554
   PubMed Web of Science ®Google Scholar
• Quenelle DC, Birkmann A, Goldner T, et al. Efficacy of pritelivir and Acyclovir in the treatment of herpes simplex virus infections in a mouse model of herpes simplex encephalitis. Antiviral Res. 2018;149:1–6. doi:10.1016/j.antiviral.2017.11.002
   PubMed Web of Science ®Google Scholar
• Gelfand JM. Autoimmune encephalitis after herpes simplex encephalitis: insights into pathogenesis. Lancet Neurol. 2018;17(9):733–735. doi:10.1016/S1474-4422(18)30279-5
   PubMed Web of Science ®Google Scholar
• Redington JJ, Tyler KL. Viral infections of the nervous system, 2002: update on diagnosis and treatment. Arch Neurol. 2002;59(5):712–718. doi:10.1001/archneur.59.5.712
   PubMedGoogle Scholar
• Mendez MD. Herpes simplex encephalitis. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2023.
   Google Scholar