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ORIGINAL RESEARCH

Comparative Analysis on Clinical Characteristics Among Patients with Acute Hepatitis A Virus (HAV) and Patients with Acute Hepatitis E Virus (HEV): A Single-Center Retrospective Study from Bulgaria

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Pages 3349-3366 | Received 08 Mar 2023, Accepted 09 May 2023, Published online: 29 May 2023

References

  • Feinstone SM, Kapikian AZ, Purceli RH. Hepatitis A: detection by immune electron microscopy of a virus like antigen associated with acute illness. Science. 1973;182:1026–1028. doi:10.1126/science.182.4116.1026
  • International Committee on Taxonomy of Viruses (ICTV). Family: picornaviridae. Available from: https://ictv.global/. Accessed March 7, 2023.
  • World Health Organization (WHO). Hepatitis A. Available from: https://www.who.int/. Accessed March 7, 2023.
  • Migueres M, Lhomme S, Izopet J. Hepatitis A: epidemiology, high-risk groups, prevention and research on antiviral treatment. Viruses. 2021;13:1900. doi:10.3390/v13101900
  • Dudareva S, Faber M, Zimmermann R, et al. Epidemiologie der virushepatitiden A bis E in Deutschland [Epidemiology of viral hepatitis A to E in Germany]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2022;65:149–158. German. doi:10.1007/s00103-021-03478-8
  • Braccio S, Irwin A, Riordan A, et al. Acute infectious hepatitis in hospitalised children: a British Paediatric Surveillance Unit study. Arch Dis Child. 2017;102:624–628. doi:10.1136/archdischild-2016-311916
  • Gargouri S, Fki Berrajah L, Ayadi I, et al. Epidemiological and clinical analysis of hepatitis virus A infections during three successive outbreaks in Sfax (Tunisia) between 2007 and 2010. Med Sante Trop. 2016;26:159–164. doi:10.1684/mst.2015.0491
  • Gotlieb N, Moradpour D, Shouval D. Hepatitis A and E – differences and commonalities. J Hepatol. 2020;72:578–580. doi:10.1016/j.jhep.2019.05.011
  • Severi E, Georgalis L, Pijnacker R, et al. Severity of the clinical presentation of hepatitis A in five European countries from 1995 to 2014. Int J Infect Dis. 2022;118:34–43. doi:10.1016/j.ijid.2022.01.053
  • Lemon SM, Walker CM. Hepatitis A virus and hepatitis E virus: emerging and re-emerging enterically transmitted hepatitis viruses. Cold Spring Harb Perspect Med. 2019;9:a031823. doi:10.1101/cshperspect.a031823
  • Pinto RM, Perez-Rodriguez FJ, Costafreda MI, et al. Pathogenicity and virulence of hepatitis A virus. Virulence. 2021;12:1174–1185. doi:10.1080/21505594.2021.1910442
  • Lemon SM. Hepatitis A: current view of an ancient disease. J Hepatol. 2022;77:243–244. doi:10.1016/j.jhep.2021.09.028
  • Castaneda D, Gonzalez AJ, Alomari M, et al. From hepatitis A to E: a critical review of viral hepatitis. World J Gastroenterol. 2021;27:1691–1715. doi:10.3748/wjg.v27.i16.1691
  • Hu X, Collier MG, Xu F. Hepatitis A outbreaks in developed countries: detection, control, and prevention. Foodborne Pathog Dis. 2020;17:166–171. doi:10.1089/fpd.2019.2648
  • Shin EC, Jeong SH. Natural history, clinical manifestations, and pathogenesis of hepatitis A. Cold Spring Harb Perspect Med. 2018;8:a031708. doi:10.1101/cshperspect.a031708
  • Dimitrova M, Petrova G, Tachkov K, et al. Economic consequences of the vaccination against hepatitis A in the Bulgarian healthcare setting. Biotechnol Biotechnol Equip. 2014;28:366–371. doi:10.1080/13102818.2014.909654
  • Bruni R, Taffon S, Equestre M, et al. Hepatitis A virus genotypes and strains from an endemic area of Europe, Bulgaria 2012–2014. BMC Infect Dis. 2017;17:497. doi:10.1186/s12879-017-2596-1
  • Toseva EI, Atanasova MV, Turnovska TH. Seroprevalence of anti-HAV total antibodies among workers in wastewater treatment plants. Int J Occup Med Environ Health. 2018;31:307–315. doi:10.13075/ijomeh.1896.01161
  • Cella E, Golkocheva-Markova EN, Trandeva-Bankova D, et al. The genetic diversity of hepatitis A genotype I in Bulgaria. Medicine. 2018;97:e9632. doi:10.1097/MD.0000000000009632
  • Velev V, Popov M, Tomov L, et al. Involvement of the gallbladder in the course of viral hepatitis A in childhood. Trop Doct. 2019;49:271–273. doi:10.1177/0049475519858893
  • European Centre for Disease Prevention and Control (ECDC). Hepatitis A: an Annual Epidemiological Reports (AERs), 2011–2021. Available from: https://www.ecdc.europa.eu/en. Accessed March 7, 2023.
  • Balayan MS, Andjaparidze AG, Savinskaya SS, et al. Evidence for a virus in non-A, non-B hepatitis transmitted via the fecal-oral route. Intervirology. 1983;20:23–31. doi:10.1159/000149370
  • International Committee on Taxonomy of Viruses (ICTV). Family: hepeviridae. Available from: https://ictv.global/. Accessed March 7, 2023.
  • Purdy MA, Drexler JF, Meng XJ, et al. ICTV virus taxonomy profile: hepeviridae 2022. J Gen Virol. 2022;103:001778. doi:10.1099/jgv.0.001778
  • World Health Organization (WHO). Hepatitis E. Available from: https://www.who.int/. Accessed March 7, 2023.
  • Nelson KE, Labrique AB, Kmush BL. Epidemiology of genotype 1 and 2 hepatitis E virus infections. Cold Spring Harb Perspect Med. 2019;9:a031732. doi:10.1101/cshperspect.a031732
  • Mooij SH, Hogema BM, Tulen AD, et al. Risk factors for hepatitis E virus seropositivity in Dutch blood donors. BMC Infect Dis. 2018;18:173. doi:10.1186/s12879-018-3078-9
  • Pepovich R, Baymakova M, Pishmisheva M, et al. Current knowledge on hepatitis E virus infection. Vojnosanit Pregl. 2019;76:733–739. doi:10.2298/VSP170815159P
  • Lee GH, Tan BH, Teo EC, et al. Chronic infection with camelid hepatitis E virus in a liver transplant recipient who regularly consumes camel meat and milk. Gastroenterology. 2016;150(2):355–7.e3. doi:10.1053/j.gastro.2015.10.048
  • Sridhar S, Yip CCY, Wu S, et al. Rat hepatitis E virus as cause of persistent hepatitis after liver transplant. Emerg Infect Dis. 2018;24:2241–2250. doi:10.3201/eid2412.180937
  • Sridhar S, Yip CC, Wu S, et al. Transmission of rat hepatitis E virus infection to humans in Hong Kong: a clinical and epidemiological analysis. Hepatology. 2021;73:10–22. doi:10.1002/hep.31138
  • Sridhar S, Yip CCY, KHY L, et al. Hepatitis E virus species C infection in humans, Hong Kong. Clin Infect Dis. 2022;75:288–296. doi:10.1093/cid/ciab919
  • Kenney SP. The current host range of hepatitis E viruses. Viruses. 2019;11:452. doi:10.3390/v11050452
  • Denner J. Hepatitis E virus (HEV) – the future. Viruses. 2019;11:251. doi:10.3390/v11030251
  • European Centre for Disease Prevention and Control (ECDC). Hepatitis E in the EU/EEA, 2005–2015. Stockholm: ECDC; 2017.
  • Baymakova M, Popov GT, Pepovich R, et al. Hepatitis E virus infection in Bulgaria: a brief analysis of the situation in the country. Open Access Maced J Med Sci. 2019;7:458–460. doi:10.3889/oamjms.2019.073
  • Khuroo MS, Kamili S. Aetiology, clinical course and outcome of sporadic acute viral hepatitis in pregnancy. J Viral Hepat. 2003;10:61–69. doi:10.1046/j.1365-2893.2003.00398.x
  • Kamar N, Selves J, Mansuy JM, et al. Hepatitis E virus and chronic hepatitis in organ-transplant recipients. N Engl J Med. 2008;358:811–817. doi:10.1056/NEJMoa0706992
  • Kamar N, Garrouste C, Haagsma EB, et al. Factors associated with chronic hepatitis in patients with hepatitis E virus infection who have received solid organ transplants. Gastroenterology. 2011;140:1481–1489. doi:10.1053/j.gastro.2011.02.050
  • Mallet V, van Bommel F, Doerig C, et al. Management of viral hepatitis in patients with haematological malignancy and in patients undergoing haemopoietic stem cell transplantation: recommendations of the 5th European Conference on Infections in Leukaemia (ECIL-5). Lancet Infect Dis. 2016;16:606–617. doi:10.1016/S1473-3099(16)00118-3
  • Jagjit Singh GK, Ijaz S, Rockwood N, et al. Chronic hepatitis E as a cause for cryptogenic cirrhosis in HIV. J Infect. 2013;66:103–106. doi:10.1016/j.jinf.2011.11.027
  • Zhu FC, Zhang J, Zhang XF, et al. Efficacy and safety of a recombinant hepatitis E vaccine in healthy adults: a large-scale, randomised, double-blind placebo-controlled, Phase 3 trial. Lancet. 2010;376:895–902. doi:10.1016/S0140-6736(10)61030-6
  • Teoharov P, Kevorkyan A, Raycheva R, et al. Data on the prevalence of hepatitis E virus in Bulgaria. Comptes Rendus Acad Bulg Sci. 2014;67:1427–1432.
  • Baymakova M, Sakem B, Plochev K, et al. Epidemiological characteristics and clinical manifestations of hepatitis E virus infection in Bulgaria: a report on 20 patients. Srp Arh Celok Lek. 2016;144:63–68. doi:10.2298/sarh1602063b
  • Bruni R, Villano U, Equestre M, et al. Hepatitis E virus genotypes and subgenotypes causing acute hepatitis, Bulgaria, 2013–2015. PLoS One. 2018;13:e0198045. doi:10.1371/journal.pone.0198045
  • Cella E, Golkocheva-Markova E, Sagnelli C, et al. Human hepatitis E virus circulation in Bulgaria: deep Bayesian phylogenetic analysis for viral spread control in the country. J Med Virol. 2019;91:132–138. doi:10.1002/jmv.25296
  • Baymakova M, Terzieva K, Popov R, et al. Seroprevalence of hepatitis E virus infection among blood donors in Bulgaria. Viruses. 2021;13:492. doi:10.3390/v13030492
  • Golkocheva-Markova E, Kevorkyan A, Raycheva R, et al. Assessment of hepatitis E seropositivity among HIV-infected patients in Bulgaria. Braz J Infect Dis. 2022;26:102329. doi:10.1016/j.bjid.2022.102329
  • National Center of Infectious and Parasitic Diseases (NCIPD). Sofia, Bulgaria. Analysis of acute infectious diseases in Bulgaria, 2011–2021. Available from: https://ncipd.org/index.php?lang=bg. Accessed March 7, 2023.
  • Pas SD, Streefkerk RH, Pronk M, et al. Diagnostic performance of selected commercial HEV IgM and IgG ELISAs for immunocompromised and immunocompetent patients. J Clin Virol. 2013;58:629–634. doi:10.1016/j.jcv.2013.10.010
  • Avellon A, Morago L, Garcia-Galera Del Carmen M, et al. Comparative sensitivity of commercial tests for hepatitis E genotype 3 virus antibody detection. J Med Virol. 2015;87:1934–1939. doi:10.1002/jmv.24251
  • Chau TN, Lai ST, Tse C, et al. Epidemiology and clinical features of sporadic hepatitis E as compared with hepatitis A. Am J Gastroenterol. 2006;101:292–296. doi:10.1111/j.1572-0241.2006.00416.x
  • Oh HW, Cha RR, Lee SS, et al. Comparing the clinical features and outcomes of acute hepatitis E viral infections with those of acute hepatitis A, B, and C infections in Korea. Intervirology. 2017;60:109–117. doi:10.1159/000480506
  • Suzuki K, Kataoka K, Miyamoto Y, et al. Clinical and molecular analyses of sporadic acute hepatitis A and E and the specific viral genotypes isolated in Iwate and three neighboring prefectures in the northern part of Honshu, Japan, between 2004 and 2013. Hepatol Res. 2015;45:714–727. doi:10.1111/hepr.12406
  • Mihai IF, Manciuc C, Hunea IM, et al. Enterically transmitted hepatitis in the third millennium in Northeastern Romania. Exp Ther Med. 2021;21:274. doi:10.3892/etm.2021.9705
  • Toyoda H, Kumada T, Kiriyama S, et al. Clinical and molecular characteristics of hepatitis A virus infections during the years 1992–2003 in Ogaki, a centrally located city of Japan. J Clin Virol. 2009;44:145–148. doi:10.1016/j.jcv.2008.12.002
  • Moon HW, Cho JH, Hur M, et al. Laboratory characteristics of recent hepatitis A in Korea: ongoing epidemiological shift. World J Gastroenterol. 2010;16:1115–1118. doi:10.3748/wjg.v16.i9.1115
  • Kwon SY, Park SH, Yeon JE, et al. Clinical characteristics and outcomes of acute hepatitis A in Korea: a nationwide multicenter study. J Korean Med Sci. 2014;29:248–253. doi:10.3346/jkms.2014.29.2.248
  • Sridhar S, Lo SK, Xing F, et al. Clinical characteristics and molecular epidemiology of hepatitis E in Shenzhen, China: a shift toward foodborne transmission of hepatitis E virus infection. Emerg Microbes Infect. 2017;6:e115. doi:10.1038/emi.2017.107
  • Fang L, Zhang J, Chen H, et al. Epidemiological characteristics and clinical manifestations of hepatitis E in a tertiary hospital in China: a retrospective study. Front Microbiol. 2022;12:831968. doi:10.3389/fmicb.2021.831968
  • Mihalcin M, Husova L, Vasickova P, et al. Hepatitis E – epidemiology and clinical course in the largest cohort in the Czech Republic. Arch Med Sci. 2022;18:1395–1398. doi:10.5114/aoms/152338
  • Tominaga A, Kanda T, Akiike T, et al. Hepatitis A outbreak associated with a revolving sushi bar in Chiba, Japan: application of molecular epidemiology. Hepatol Res. 2012;42:828–834. doi:10.1111/j.1872-034X.2012.00988.x
  • Pishmisheva М, Golkocheva-Markova Е, Naseva Е, et al. Анализ на някои епидемиологични и клинични характеристики на ентерално предаваните хепатити А и Е (собствени наблюдения) [Analysis of some epidemiological and clinical characteristics of enterally transmitted hepatitis A and E (our own observations)]. Med Rev. 2018;54:30–35. Bulgarian.
  • Pishmisheva-Peleva М Хепатит Е: екзотика или тихо присъствие (монография) [Hepatitis E: exoticism or silent presence (monograph)]. Pazardzhik, Bulgaria: Barich & Co Ltd; 2022. Bulgarian.