Prevalence of Multidrug-Resistant Pathogens Causing Neonatal Early and Late Onset Sepsis, a Retrospective Study from the Tertiary Referral Children’s Hospital

References

• Fleiss N, Coggins SA, Lewis AN, et al. Evaluation of the neonatal sequential organ failure assessment and mortality risk in preterm infants with late-onset infection. JAMA Netw Open. 2021;4(2):e2036518.
   PubMed Web of Science ®Google Scholar
• Shane AL, Sánchez PJ, Stoll BJ. Neonatal sepsis. Lancet. 2017;390(10104):1770–1780.
   PubMed Web of Science ®Google Scholar
• Wang H, Abajobir AA, Abate KH. Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017;390(10100):1084–1150.
   PubMed Web of Science ®Google Scholar
• Vos T, Lim SS, Abbafati C. Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020;396(10258):1204–1222.
   PubMed Web of Science ®Google Scholar
• He C, Liu L, Chu Y, et al. National and subnational all-cause and cause-specific child mortality in China, 1996-2015: a systematic analysis with implications for the Sustainable Development Goals. Lancet Glob Health. 2017;5(2):e186–e197.
   PubMed Web of Science ®Google Scholar
• Dong Y, Basmaci R, Titomanlio L, et al. Neonatal sepsis: within and beyond China. Chin Med J. 2020;133(18):2219–2228.
   PubMed Web of Science ®Google Scholar
• Juliana AE, Holband N, Lissone NPA, et al. Incidence of early and late onset neonatal sepsis in suriname: a national tertiary hospital birth-cohort study. Pediatr Infect Dis J. 2022;41(12):1007–1011.
   PubMed Web of Science ®Google Scholar
• Yadav P, Yadav SK. Progress in Diagnosis and Treatment of Neonatal Sepsis: a Review Article. JNMA J Nepal Med Assoc. 2022;60(247):318–324.
   PubMed Web of Science ®Google Scholar
• Mariani M, Parodi A, Minghetti D, et al. Early and Late Onset Neonatal Sepsis: epidemiology and Effectiveness of Empirical Antibacterial Therapy in a III Level Neonatal Intensive Care Unit. Antibiotics. 2022;11(2):65.
   Google Scholar
• Pace E, Yanowitz T. Infections in the NICU: neonatal sepsis. Semin Pediatr Surg. 2022;31(4):151200.
   PubMed Web of Science ®Google Scholar
• Ren Y, Chakraborty T, Doijad S, et al. Multi-label classification for multi-drug resistance prediction of Escherichia coli. Comput Struct Biotechnol J. 2022;20:1264–1270.
   PubMed Web of Science ®Google Scholar
• Golli AL, Cristea OM, Zlatian O, et al. Prevalence of Multidrug-Resistant Pathogens Causing Bloodstream Infections in an Intensive Care Unit. Infect Drug Resist. 2022;15:5981–5992.
   PubMed Web of Science ®Google Scholar
• Robledo J, Maldonado N, Robledo C, et al. Changes in Antimicrobial Resistance and Etiology of Blood Culture Isolates: results of a Decade (2010-2019) of Surveillance in a Northern Region of Colombia. Infect Drug Resist. 2022;15:6067–6079.
   PubMed Web of Science ®Google Scholar
• Hu F, Yuan L, Yang Y, et al. A multicenter investigation of 2773 cases of bloodstream infections based on China antimicrobial surveillance network (CHINET). Front Cell Infect Microbiol. 2022;12:1075185.
   PubMed Web of Science ®Google Scholar
• Haddad S, Jabbour JF, Hindy JR, et al. Bacterial bloodstream infections and patterns of resistance in patients with haematological malignancies at a tertiary centre in Lebanon over 10 years. J Glob Antimicrob Resist. 2021;27:228–235.
   PubMed Web of Science ®Google Scholar
• Simonsen KA, Anderson-Berry AL, Delair SF, et al. Early-onset neonatal sepsis. Clin Microbiol Rev. 2014;27(1):21–47.
   PubMed Web of Science ®Google Scholar
• National Institute for Health and Care Excellence. Clinical Guidelines. Neonatal Infection: Antibiotics for Prevention and Treatment. London: National Institute for Health and Care Excellence (NICE) Copyright © NICE 2021; 2021.
   Google Scholar
• Magiorakos AP, Srinivasan A, Carey RB, et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect. 2012;18(3):268–281.
   PubMed Web of Science ®Google Scholar
• Rafailidis PI, Kofteridis D. Proposed amendments regarding the definitions of multidrug-resistant and extensively drug-resistant bacteria. Expert Rev Anti Infect Ther. 2022;20(2):139–146.
   PubMed Web of Science ®Google Scholar
• Fraimow HS, Tsigrelis C. Antimicrobial resistance in the intensive care unit: mechanisms, epidemiology, and management of specific resistant pathogens. Crit Care Clin. 2011;27(1):163–205.
   PubMed Web of Science ®Google Scholar
• CLSI. Performance Standards for Antimicrobial Susceptibility Testing. 31th ed. Wayne: Clinical and Laboratory Standards Institute; 2021.
   Google Scholar
• Ren Z, Yang S, Han J, et al. Reduction of antibiotic use and multi-drug resistance bacteria infection in neonates after improvement of antibiotics use strategy in a level 4 neonatal intensive care unit in southern China. Eur J Clin Microbiol Infect Dis. 2023;42(1):87–98.
   PubMed Web of Science ®Google Scholar
• Panigrahi K, Pathi BK, Poddar N, et al. Colistin resistance among multi-drug resistant gram-negative bacterial isolates from different clinical samples of ICU patients: prevalence and clinical outcomes. Cureus. 2022;14(8):e28317.
   PubMed Web of Science ®Google Scholar
• Al-Sunaidar KA, Aziz NA, Hassan Y, et al. Association of multidrug resistance bacteria and clinical outcomes of adult patients with sepsis in the intensive care unit. Trop Med Infect Dis. 2022;7(11):98.
   PubMedGoogle Scholar
• Kim HJ, Oh DK, Lim SY, et al. Antibiogram of multidrug-resistant bacteria based on sepsis onset location in Korea: a multicenter cohort study. J Korean Med Sci. 2023;38(10):e75.
   PubMed Web of Science ®Google Scholar
• Legese MH, Asrat D, Swedberg G, et al. Sepsis: emerging pathogens and antimicrobial resistance in Ethiopian referral hospitals. Antimicrob Resist Infect Control. 2022;11(1):83.
   PubMed Web of Science ®Google Scholar
• Qiu Y, Yang J, Chen Y, et al. Microbiological profiles and antimicrobial resistance patterns of pediatric bloodstream pathogens in China, 2016-2018. Eur J Clin Microbiol Infect Dis. 2021;40(4):739–749.
   PubMed Web of Science ®Google Scholar
• Oxman D, Lohr K, Gupta E, et al. Incidence of multidrug resistant infections in emergency department patients with suspected sepsis. Am J Med Sci. 2020;360(6):650–655.
   PubMed Web of Science ®Google Scholar
• Størdal EH, Solevåg AL, Bjørnholt JV, et al. Sepsis treatment options identified by 10-year study of microbial isolates and antibiotic susceptibility in a level-four neonatal intensive care unit. Acta Paediatr. 2022;111(3):519–526.
   PubMed Web of Science ®Google Scholar
• Wang J, Zhang H, Yan J, et al. Literature review on the distribution characteristics and antimicrobial resistance of bacterial pathogens in neonatal sepsis. J Matern Fetal Neonatal Med. 2022;35(5):861–870.
   PubMed Web of Science ®Google Scholar
• Zhou W, Niu D, Gao S, et al. Prevalence, biofilm formation, and mass spectrometric characterization of linezolid-resistant Staphylococcus capitis isolated from a tertiary hospital in China. J Glob Antimicrob Resist. 2023:56.
   PubMed Web of Science ®Google Scholar
• Gowda H, Norton R, White A, et al. Late-onset Neonatal Sepsis-A 10-year Review From North Queensland, Australia. Pediatr Infect Dis J. 2017;36(9):883–888.
   PubMed Web of Science ®Google Scholar
• Ji H, Yu Y, Huang L, et al. Pathogen Distribution and Antimicrobial Resistance of Early Onset Sepsis in Very Premature Infants: a Real-World Study. Infect Dis Ther. 2022;11(5):1935–1947.
   PubMed Web of Science ®Google Scholar
• Köstlin-Gille N, Härtel C, Haug C, et al. Epidemiology of early and late onset neonatal sepsis in very low birthweight infants: data from the German neonatal network. Pediatr Infect Dis J. 2021;40(3):255–259.
   PubMed Web of Science ®Google Scholar
• França A. The Role of Coagulase-Negative Staphylococci Biofilms on Late-Onset Sepsis: current Challenges and Emerging Diagnostics and Therapies. Antibiotics. 2023;12(3):23.
   Google Scholar
• Wong JR, Bauer KA, Mangino JE, et al. Antimicrobial stewardship pharmacist interventions for coagulase-negative staphylococci positive blood cultures using rapid polymerase chain reaction. Ann Pharmacother. 2012;46(11):1484–1490.
   PubMed Web of Science ®Google Scholar
• Aleidan FAS, Alkhelaifi H, Alsenaid A, et al. Incidence and risk factors of carbapenem-resistant Enterobacteriaceae infection in intensive care units: a matched case-control study. Expert Rev Anti Infect Ther. 2021;19(3):393–398.
   PubMed Web of Science ®Google Scholar
• Chaurasia S, Sivanandan S, Agarwal R, et al. Neonatal sepsis in South Asia: huge burden and spiralling antimicrobial resistance. BMJ. 2019;364:k5314.
   PubMedGoogle Scholar
• Liu J, Fang Z, Yu Y, et al. Pathogens distribution and antimicrobial resistance in bloodstream infections in twenty-five neonatal intensive care units in China, 2017-2019. Antimicrob Resist Infect Control. 2021;10(1):121.
   PubMed Web of Science ®Google Scholar
• Narimisa N, Goodarzi F, Bavari S. Prevalence of colistin resistance of Klebsiella pneumoniae isolates in Iran: a systematic review and meta-analysis. Ann Clin Microbiol Antimicrob. 2022;21(1):29.
   PubMed Web of Science ®Google Scholar
• Ardebili A, Izanloo A, Rastegar M. Polymyxin combination therapy for multidrug-resistant, extensively-drug resistant, and difficult-to-treat drug-resistant gram-negative infections: is it superior to polymyxin monotherapy? Expert Rev Anti Infect Ther. 2023;21(4):387–429.
   PubMed Web of Science ®Google Scholar
• Liu YC, Lu CY, Yen TY, et al. Clinical characteristics and outcomes of carbapenem-resistant Enterobacterales bacteremia in pediatric patients. J Microbiol Immunol Infect. 2023;56(1):84–92.
   PubMedGoogle Scholar
• Della Rocca MT, Panetta V, Durante A, et al. Pathogens distribution and antimicrobial resistance pattern of blood stream infections in Southern Italian hospital, 2016-2021 surveillance. New Microbiol. 2023;46(1):29–36.
   PubMed Web of Science ®Google Scholar
• Chen CH, Wu PH, Lu MC, et al. National surveillance of antimicrobial susceptibilities to ceftaroline, dalbavancin, telavancin, tedizolid, eravacycline, omadacycline, and other comparator antibiotics, and genetic characteristics of bacteremic Staphylococcus aureus isolates in adults: results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART) program in 2020. Int J Antimicrob Agents. 2023;61(4):106745.
   PubMed Web of Science ®Google Scholar
• Ohnuma T, Chihara S, Costin B, et al. Association of Appropriate Empirical Antimicrobial Therapy With In-Hospital Mortality in Patients With Bloodstream Infections in the US. JAMA Netw Open. 2023;6(1):e2249353.
   PubMed Web of Science ®Google Scholar
• Austin ED, Sullivan SS, Macesic N, et al. Reduced Mortality of Staphylococcus aureus Bacteremia in a Retrospective Cohort Study of 2139 Patients: 2007-2015. Clin Infect Dis. 2020;70(8):1666–1674.
   PubMed Web of Science ®Google Scholar
• Gao K, Fu J, Guan X, et al. Incidence, Bacterial Profiles, And Antimicrobial Resistance Of Culture-Proven Neonatal Sepsis In South China. Infect Drug Resist. 2019;12:3797–3805.
   PubMed Web of Science ®Google Scholar
• Kufel WD, Parsels KA, Blaine BE, et al. Vancomycin plus ceftaroline for persistent methicillin-resistant Staphylococcus aureus bacteremia. Pharmacotherapy. 2023;43(1):15–23.
   PubMed Web of Science ®Google Scholar
• Patel D, Brown ML, Edwards S, et al. Outcomes of Daptomycin Plus Ceftaroline Versus Alternative Therapy for Persistent Methicillin-resistant Staphylococcus aureus (MRSA) Bacteraemia. Int J Antimicrob Agents. 2023;61(3):106735.
   PubMed Web of Science ®Google Scholar
• Jena B, Singh SS, Behera SK, et al. To decipher the phytochemical agent and mechanism for Urginea indica mediated green synthesis of Ag nanoparticles and investigation of its antibacterial activity against Methicillin-resistant Staphylococcus aureus. Environ Res. 2023;216(Pt 4):114700.
   PubMedGoogle Scholar
• Li T, Li X, Gao K, et al. Changes in pathogen distribution in the blood culture of neonates before and after the COVID-19 pandemic, Henan, China. J Infect. 2023;86(2):154–225.
   Web of Science ®Google Scholar