Glabridin Functions as a Quorum Sensing Inhibitor to Inhibit Biofilm Formation and Swarming Motility of Multidrug-Resistant Acinetobacter baumannii

References

• Qureshi ZA, Hittle LE, O’Hara JA, et al. Colistin-resistant Acinetobacter baumannii: beyond carbapenem resistance. Clin Infect Dis. 2015;60(9):1295–1303. doi:10.1093/cid/civ048
   PubMed Web of Science ®Google Scholar
• Murray CJL, Ikuta KS, Sharara F; Antimicrobial Resistance C. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet. 2022;399(10325):629–655. doi:10.1016/S0140-6736(21)02724-0
   PubMed Web of Science ®Google Scholar
• Kalia VC, Patel SKS, Kang YC, Lee JK. Quorum sensing inhibitors as antipathogens: biotechnological applications. Biotechnol Adv. 2019;37(1):68–90. doi:10.1016/j.biotechadv.2018.11.006
   PubMed Web of Science ®Google Scholar
• Lamin A, Kaksonen AH, Cole IS, Chen XB. Quorum sensing inhibitors applications: a new prospect for mitigation of microbiologically influenced corrosion. Bioelectrochemistry. 2022;145:108050. doi:10.1016/j.bioelechem.2022.108050
   PubMed Web of Science ®Google Scholar
• Wang L, Yang R, Yuan B, Liu Y, Liu C. The antiviral and antimicrobial activities of licorice, a widely-used Chinese herb. Acta Pharm Sin B. 2015;5(4):310–315. doi:10.1016/j.apsb.2015.05.005
   PubMed Web of Science ®Google Scholar
• Simmler C, Pauli GF, Chen SN. Phytochemistry and biological properties of glabridin. Fitoterapia. 2013;90:160–184. doi:10.1016/j.fitote.2013.07.003
   PubMed Web of Science ®Google Scholar
• Vaillancourt K, LeBel G, Pellerin G, Ben Lagha A, Grenier D. Effects of the licorice isoflavans licoricidin and glabridin on the growth, adherence properties, and acid production of Streptococcus mutans, and assessment of their biocompatibility. Antibiotics. 2021;10(2). doi:10.3390/antibiotics10020163
   Google Scholar
• Bhargava N, Singh SP, Sharma A, Sharma P, Capalash N. Attenuation of quorum sensing-mediated virulence of Acinetobacter baumannii by Glycyrrhiza glabra flavonoids. Future Microbiol. 2015;10(12):1953–1968. doi:10.2217/fmb.15.107
   PubMed Web of Science ®Google Scholar
• Shi S, Zhang X, Yao Z, et al. Synergistic effect of the novel beta-lactamase inhibitor BLI-489 combined with imipenem or meropenem against diverse carbapenemase-producing carbapenem-resistant Enterobacterales. J Antimicrob Chemother. 2022;77(5):1301–1305. doi:10.1093/jac/dkac037
   PubMed Web of Science ®Google Scholar
• Xiao R, Li Y, Liu X, et al. Antibiotic susceptibility of Escherichia coli isolated from neonates admitted to neonatal intensive care units across China from 2015 to 2020. Front Cell Infect Microbiol. 2023;13:1183736. doi:10.3389/fcimb.2023.1183736
   PubMed Web of Science ®Google Scholar
• Gangwar B, Kumar S, Darokar MP. Glabridin averts biofilms formation in methicillin-resistant staphylococcus aureus by modulation of the surfaceome. Front Microbiol. 2020;11:1779. doi:10.3389/fmicb.2020.01779
   PubMed Web of Science ®Google Scholar
• Wang H, Chu W, Ye C, et al. Chlorogenic acid attenuates virulence factors and pathogenicity of Pseudomonas aeruginosa by regulating quorum sensing. Appl Microbiol Biotechnol. 2019;103(2):903–915. doi:10.1007/s00253-018-9482-7
   PubMed Web of Science ®Google Scholar
• Wu Z, He R, Zhang R, Yuan J. Swarming motility without flagellar motor switching by reversal of swimming direction in E. coli. Front Microbiol. 2020;11:1042. doi:10.3389/fmicb.2020.01042
   PubMed Web of Science ®Google Scholar
• Navidifar T, Amin M, Rashno M. Effects of sub-inhibitory concentrations of meropenem and tigecycline on the expression of genes regulating pili, efflux pumps and virulence factors involved in biofilm formation by Acinetobacter baumannii. Infect Drug Resist. 2019;12:1099–1111. doi:10.2147/IDR.S199993
   PubMed Web of Science ®Google Scholar
• Fernando DM, Xu W, Loewen PC, Zhanel GG, Kumar A. Triclosan can select for an AdeIJK-overexpressing mutant of Acinetobacter baumannii ATCC 17978 that displays reduced susceptibility to multiple antibiotics. Antimicrob Agents Chemother. 2014;58(11):6424–6431. doi:10.1128/AAC.03074-14
   PubMed Web of Science ®Google Scholar
• Aleksic Sabo V, Skoric D, Jovanovic-Santa S, Nikolic I, Janos C, Knezevic P. Synergistic activity of bile salts and their derivatives in combination with conventional antimicrobial agents against Acinetobacter baumannii. J Ethnopharmacol. 2021;264:113266. doi:10.1016/j.jep.2020.113266
   PubMed Web of Science ®Google Scholar
• Roy S, Chowdhury G, Mukhopadhyay AK, Dutta S, Basu S. Convergence of biofilm formation and antibiotic resistance in Acinetobacter baumannii Infection. Front Med. 2022;9:793615. doi:10.3389/fmed.2022.793615
   Web of Science ®Google Scholar
• Lopez-Martin M, Dubern JF, Alexander MR, Williams P, Brun YV. AbaM regulates quorum sensing, biofilm formation, and virulence in Acinetobacter baumannii. J Bacteriol. 2021;203(8). doi:10.1128/JB.00635-20
   PubMed Web of Science ®Google Scholar
• Bouyahya A, Chamkhi I, Balahbib A, et al. Mechanisms, anti-quorum-sensing actions, and clinical trials of medicinal plant bioactive compounds against bacteria: a comprehensive review. Molecules. 2022;27(5):1484. doi:10.3390/molecules27051484
   PubMed Web of Science ®Google Scholar
• Niu C, Clemmer KM, Bonomo RA, Rather PN. Isolation and characterization of an autoinducer synthase from Acinetobacter baumannii. J Bacteriol. 2008;190(9):3386–3392. doi:10.1128/JB.01929-07
   PubMed Web of Science ®Google Scholar
• Maeda T, Garcia-Contreras R, Pu M, et al. Quorum quenching quandary: resistance to antivirulence compounds. ISME J. 2012;6(3):493–501. doi:10.1038/ismej.2011.122
   PubMed Web of Science ®Google Scholar
• Chen F, Gao Y, Chen X, Yu Z, Li X. Quorum quenching enzymes and their application in degrading signal molecules to block quorum sensing-dependent infection. Int J Mol Sci. 2013;14(9):17477–17500. doi:10.3390/ijms140917477
   PubMed Web of Science ®Google Scholar
• Hoang TT, Schweizer HP. Characterization of Pseudomonas aeruginosa enoyl-acyl carrier protein reductase (FabI): a target for the antimicrobial triclosan and its role in acylated homoserine lactone synthesis. J Bacteriol. 1999;181(17):5489–5497. doi:10.1128/JB.181.17.5489-5497.1999
   PubMed Web of Science ®Google Scholar
• Schramm VL, Gutierrez JA, Cordovano G, et al. Transition state analogues in quorum sensing and SAM recycling. Nucleic Acids Symp Ser. 2008;52(1):75–76. doi:10.1093/nass/nrn038
   Google Scholar
• Vandeputte OM, Kiendrebeogo M, Rasamiravaka T, et al. The flavanone naringenin reduces the production of quorum sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1. Microbiology. 2011;157(Pt 7):2120–2132. doi:10.1099/mic.0.049338-0
   PubMedGoogle Scholar