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ORIGINAL RESEARCH

The Etiological and Drug Resistance Characteristics of Multidrug-Resistant Pathogens in Patients Requiring Extracorporeal Membrane Oxygenation: A Retrospective Cohort Study

ORCID Icon & ORCID Icon
Pages 4929-4941 | Received 15 May 2023, Accepted 19 Jul 2023, Published online: 31 Jul 2023

References

  • Angel ND, Amir MM, Naomi H, et al. Antimicrobial resistance and human mobility. Infect Drug Resist. 2022;15:127–133.
  • Dadgostar P. Antimicrobial resistance: implications and costs. Infect Drug Resist. 2019;12:3903–3910. doi:10.2147/IDR.S234610
  • Ying Z, Wei EH, Qiwen Y. Clinical perspective of antimicrobial resistance in bacteria. Infect Drug Resist. 2022;15:735–746.
  • Gowri R, Esther EA, Jeffrey C, et al. Risk factors for hospitalized patients with resistant or multidrug-resistant Pseudomonas aeruginosa infections: a systematic review and meta-analysis. Antimicrob Resist Infect Control. 2018;7:79. doi:10.1186/s13756-018-0370-9
  • Palacios-Baena ZR, Giannella M, Manissero D, et al. Risk factors for carbapenem-resistant gram-negative bacterial infections: a systematic review. Clin Microbiol Infect. 2021;27(2):228–235. doi:10.1016/j.cmi.2020.10.016
  • Schweickhardt SK, Sams VG, Radowsky JS, et al. Infections complicating extracorporeal membrane oxygenation in patients with traumatic injuries. Injury. 2023;54(2):405–408. doi:10.1016/j.injury.2022.11.048
  • Boscolo A, Sella N, Pettenuzzo T, et al. Multidrug-resistant and extended-spectrum β-lactamase gram-negative bacteria in bilateral lung transplant recipients: incidence, risk factors, and in-hospital mortality. Chest. 2022;162(6):1255–1264. doi:10.1016/j.chest.2022.06.046
  • Petros IR, Diamantis K. Proposed amendments regarding the definitions of multidrug-resistant and extensively drug-resistant bacteria. Expert Rev Anti Infect Ther. 2022;20(2):139–146. doi:10.1080/14787210.2021.1945922
  • Romney H, April MB, Janet AH, et al. Overview of changes to the clinical and laboratory standards institute performance standards for antimicrobial susceptibility testing, M100, 31st edition. J Clin Microbiol. 2021;59(12):e0021321. doi:10.1128/JCM.00213-21
  • Xiyuan L, Liangshan W, Hong W, et al. Outcome and clinical characteristics of nosocomial infection in adult patients undergoing extracorporeal membrane oxygenation: a systematic review and meta-analysis. Front Public Health. 2022;10:857873. doi:10.3389/fpubh.2022.857873
  • Bouglé A, Bombled C, Margetis D, et al. Ventilator-associated pneumonia in patients assisted by veno-arterial extracorporeal membrane oxygenation support: epidemiology and risk factors of treatment failure. PLoS One. 2018;13(4):e0194976. doi:10.1371/journal.pone.0194976
  • Simona S, Marco R, Valeria P, et al. Bloodstream infections during post-cardiotomy extracorporeal membrane oxygenation: incidence, risk factors, and outcomes. Int J Artif Organs. 2019;42(6):299–306. doi:10.1177/0391398818817325
  • Roman K, Alexey K. The dynamics of antimicrobial resistance among Enterobacteriaceae isolates in Russia: results of the 2012–2018 INFORM and ATLAS international program studies. Antibiotics. 2022;11(6):790. doi:10.3390/antibiotics11060790
  • Teerawattanapong N, Kengkla K, Dilokthornsakul P, et al. Prevention and control of multidrug-resistant gram-negative bacteria in adult intensive care units: a systematic review and network meta-analysis. Clin Infect Dis. 2017;64(Suppl suppl_2):S51–S60. doi:10.1093/cid/cix112
  • JongHoon H, Sang Kil L, Jae Hee C, et al. Faecal microbiota transplantation reduces amounts of antibiotic resistance genes in patients with multidrug-resistant organisms. Antimicrob Resist Infect Control. 2022;11(1):20. doi:10.1186/s13756-022-01064-4
  • Aya Y, Yoshihiko N, Shiho H, et al. The association between the oral-gut axis and the outcomes of severe COVID-19 patients receiving extracorporeal membrane oxygenation: a case-control study. J Clin Med. 2022;11(5):1167. doi:10.3390/jcm11051167
  • Giacomo G, Vittorio S, Laura A, et al. Gastrointestinal colonization with multidrug-resistant gram-negative bacteria during extracorporeal membrane oxygenation: effect on the risk of subsequent infections and impact on patient outcome. Ann Intensive Care. 2019;9(1):141. doi:10.1186/s13613-019-0615-7
  • Jessica T, Rafael Almeida DA, Nasia S. Risk of infection following colonization with carbapenem-resistant Enterobactericeae: a systematic review. Am J Infect Control. 2016;44(5):539–543. doi:10.1016/j.ajic.2015.12.005
  • Gupta R, Malik A, Rizvi M, Ahmed M, Singh A. Epidemiology of multidrug-resistant gram-negative pathogens isolated from ventilator-associated pneumonia in ICU patients. J Glob Antimicrob Resist. 2017;9:47–50. doi:10.1016/j.jgar.2016.12.016
  • Meštrović T. Antimicrobial resistance in Klebsiella pneumoniae as an independent risk factor for bacteraemia-related mortality. Hong Kong Med J. 2021;27(5):385. doi:10.12809/hkmj219773
  • Xiaohua Q, Shi W, Min H, et al. The colonization of carbapenem-resistant Klebsiella pneumoniae: epidemiology, resistance mechanisms, and risk factors in patients admitted to intensive care units in China. J Infect Dis. 2020;221(Suppl 2):S206–S214. doi:10.1093/infdis/jiz622
  • Stephen MB, Daniel R, Peter K, et al. Trends in hospital-acquired and ventilator-associated bacterial pneumonia trials. Clin Infect Dis. 2021;73(3):e602–e608. doi:10.1093/cid/ciaa1712
  • Natalia B, Anthony DH, Clare R, et al. Risk factors and outcomes associated with multidrug-resistant Acinetobacter baumannii upon intensive care unit admission. Antimicrob Agents Chemother. 2017;62(1):e01631–e01617. doi:10.1128/AAC.01631-17
  • Evgeni B, Abraham B, Leonid K, et al. Multidrug resistance Acinetobacter bacteremia secondary to ventilator-associated pneumonia: risk factors and outcome. J Intensive Care Med. 2017;32(9):528–534. doi:10.1177/0885066616632193
  • Wenzhong P, Yanhao W, Rongli L, et al. Successful treatment of acute respiratory distress syndrome caused by hypervirulent Klebsiella pneumoniae with extracorporeal membrane oxygenation and continuous renal replacement therapy: a case report and literature review. Front Med. 2022;9:936927. doi:10.3389/fmed.2022.936927
  • Karaiskos I, Lagou S, Pontikis K, et al. The “old” and the “new” antibiotics for MDR gram-negative pathogens: for whom, when, and how. Front Public Health. 2019;7:151. doi:10.3389/fpubh.2019.00151
  • Monsel A, Torres A, Yinggang Z, et al. Nebulized antibiotics for ventilator-associated pneumonia: methodological framework for future multicenter randomized controlled trials. Curr Opin Infect Dis. 2021;34(2):156–168. doi:10.1097/QCO.0000000000000720
  • Nguyen M, Joshi SG. Carbapenem resistance in Acinetobacter baumannii, and their importance in hospital-acquired infections: a scientific review. J Appl Microbiol. 2021;131(6):2715–2738. doi:10.1111/jam.15130
  • Swati S, Tuhina B, Ashok K, et al. Extensive outbreak of colistin resistant, carbapenemase (blaOXA-48, blaNDM) producing Klebsiella pneumoniae in a large tertiary care hospital, India. Antimicrob Resist Infect Control. 2022;11(1):1. doi:10.1186/s13756-021-01048-w
  • Yudong L, Qi W, Chunjiang Z, et al. Prospective multi-center evaluation on risk factors, clinical characteristics and outcomes due to carbapenem resistance in Acinetobacter baumannii complex bacteraemia: experience from the Chinese antimicrobial resistance surveillance of nosocomial infections (CARES) network. J Med Microbiol. 2020;69(7):949–959. doi:10.1099/jmm.0.001222
  • Karaiskos I, Giamarellou H. Carbapenem-sparing strategies for ESBL producers: when and how. Antibiotics. 2020;9(2):61. doi:10.3390/antibiotics9020061
  • Yuan T, QiaoYu Z, LiRong W, Jiansen C. Combined effect of polymyxin B and tigecycline to overcome heteroresistance in carbapenem-resistant Klebsiella pneumoniae. Microbiol Spectr. 2021;9(2):e0015221. doi:10.1128/Spectrum.00152-21
  • Yuan Z, Hongbin H, Qing Z, et al. Effects of ex vivo extracorporeal membrane oxygenation circuits on sequestration of antimicrobial agents. Front Med. 2021;8:748769. doi:10.3389/fmed.2021.748769
  • Čiginskienė A, Dambrauskienė A, Rello J, et al. Ventilator-associated pneumonia due to drug-resistant Acinetobacter baumannii: risk factors and mortality relation with resistance profiles, and independent predictors of in-hospital mortality. Medicina. 2019;55(2):49. doi:10.3390/medicina55020049
  • Lei Z, Xue Z, Yusheng C, et al. Intravenous polymyxin B as adjunctive therapy to high-dose tigecycline for the treatment of nosocomial pneumonia due to carbapenem-resistant Acinetobacter baumannii and Klebsiella pneumoniae: a propensity score-matched cohort study. Antibiotics. 2023;12(2):273. doi:10.3390/antibiotics12020273
  • Pavel S, Jitka R. Pharmacokinetics of colistin during extracorporeal membrane oxygenation. J Antimicrob Chemother. 2022;77(8):2298–2300. doi:10.1093/jac/dkac163
  • Brinkmann A, Röhr AC, Köberer A, et al. Therapeutisches Drug Monitoring und individualisierte Dosierung von Antibiotika bei der Sepsis [Therapeutic drug monitoring and individual dosing of antibiotics during sepsis: modern or just “trendy”?]. Med Klin Intensivmed Notfmed. 2018;113(2):82–93. German. doi:10.1007/s00063-016-0213-5
  • Kühn D, Metz C, Seiler F, et al. Antibiotic therapeutic drug monitoring in intensive care patients treated with different modalities of extracorporeal membrane oxygenation (ECMO) and renal replacement therapy: a prospective, observational single-center study. Crit Care. 2020;24(1):664. doi:10.1186/s13054-020-03397-1
  • Dalhoff K, Abele-Horn M, Andreas S, et al. S3-Leitlinie der Deutschen Gesellschaft für Anästhesiologie und Intensivmedizin e.V., der Deutschen Gesellschaft für Infektiologie e.V., der Deutschen Gesellschaft für Hygiene und Mikrobiologie e.V., der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e.V., der Paul-Ehrlich Gesellschaft für Chemotherapie e.V, der Deutschen Röntgengesellschaft und der Gesellschaft für Virologie[Epidemiology, diagnosis and treatment of adult patients with nosocomial pneumonia - update 2017 - S3 guideline of the German society for anaesthesiology and intensive care medicine, the German society for infectious diseases, the German society for hygiene and microbiology, the German respiratory society and the Paul-Ehrlich-society for chemotherapy, the German radiological society and the society for virology]. Pneumologie. 2018;72(1):15–63. German. doi:10.1055/s-0043-121734
  • Abdul-Aziz MH, Roberts JA. Antibiotic dosing during extracorporeal membrane oxygenation: does the system matter? Curr Opin Anaesthesiol. 2020;33:71–82. doi:10.1097/ACO.0000000000000810