Protectin DX Relieve Hyperoxia‐induced Lung Injury by Protecting Pulmonary Endothelial Glycocalyx

References

• Thebaud B, Goss KN, Laughon M, et al. Bronchopulmonary dysplasia. Nat Rev Dis Primers. 2019;5(1):78. doi:10.1038/s41572-019-0127-7
   PubMed Web of Science ®Google Scholar
• Marc I, Piedboeuf B, Lacaze-Masmonteil T, et al. Effect of maternal docosahexaenoic acid supplementation on bronchopulmonary dysplasia-free survival in breastfed preterm infants: a randomized clinical trial. JAMA. 2020;324(2):157–167. doi:10.1001/jama.2020.8896
   PubMed Web of Science ®Google Scholar
• Kirpalani H, Ratcliffe SJ, Keszler M, et al. Effect of sustained inflations vs intermittent positive pressure ventilation on bronchopulmonary dysplasia or death among extremely preterm infants: the SAIL randomized clinical trial. JAMA. 2019;321(12):1165–1175. doi:10.1001/jama.2019.1660
   PubMed Web of Science ®Google Scholar
• Bassler D, Shinwell ES, Hallman M, et al. Long-term effects of inhaled budesonide for bronchopulmonary dysplasia. N Engl J Med. 2018;378(2):148–157. doi:10.1056/NEJMoa1708831
   Web of Science ®Google Scholar
• Ruan Y, Dong W, Kang L, et al. The changes of twist1 pathway in pulmonary microvascular permeability in a newborn rat model of hyperoxia-induced acute lung injury. Front Pediatr. 2020;8:190. doi:10.3389/fped.2020.00190
   PubMed Web of Science ®Google Scholar
• Thome UH, Bischoff A, Maier L, et al. Amiloride-sensitive nasal potential difference is not changed by estradiol and progesterone replacement but relates to BPD or death in a randomized trial on preterm infants. Pediatr Res. 2006;60(5):619–623. doi:10.1203/01.pdr.0000242262.55324.aa
   Web of Science ®Google Scholar
• Ji W, Fu J, Nie H, et al. Expression and activity of epithelial sodium channel in hyperoxia-induced bronchopulmonary dysplasia in neonatal rats. Pediatr Int. 2012;54(6):735–742. doi:10.1111/j.1442-200X.2012.03662.x
   Web of Science ®Google Scholar
• Huber-Lang M, Lambris JD, Ward PA. Innate immune responses to trauma. Nat Immunol. 2018;19(4):327–341. doi:10.1038/s41590-018-0064-8
   PubMed Web of Science ®Google Scholar
• Schmidt EP, Yang Y, Janssen WJ, et al. The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis. Nat Med. 2012;18(8):1217–1223. doi:10.1038/nm.2843
   PubMed Web of Science ®Google Scholar
• Villalba N, Baby S, Yuan SY. The endothelial glycocalyx as a double-edged sword in microvascular homeostasis and pathogenesis. Front Cell Dev Biol. 2021;9:711003. doi:10.3389/fcell.2021.711003
   PubMed Web of Science ®Google Scholar
• De Pasquale V, Quiccione MS, Tafuri S, et al. Heparan sulfate proteoglycans in viral infection and treatment: a special focus on SARS-CoV-2. Int J Mol Sci. 2021;22(12):6574. doi:10.3390/ijms22126574
   Web of Science ®Google Scholar
• Jungraithmayr W. Novel strategies for endothelial preservation in lung transplant ischemia-reperfusion injury. Front Physiol. 2020;11:581420. doi:10.3389/fphys.2020.581420
   PubMed Web of Science ®Google Scholar
• LaRiviere WB, Schmidt EP. The pulmonary endothelial glycocalyx in ARDS: a critical role for heparan sulfate. Curr Top Membr. 2018;82:33–52.
   Web of Science ®Google Scholar
• Puchwein-Schwepcke A, Genzel-Boroviczeny O, Nussbaum C. The endothelial glycocalyx: physiology and pathology in neonates, infants and children. Front Cell Dev Biol. 2021;9:733557. doi:10.3389/fcell.2021.733557
   Web of Science ®Google Scholar
• Chappell D, Jacob M, Rehm M, et al. Heparinase selectively sheds heparan sulphate from the endothelial glycocalyx. Biol Chem. 2008;389(1):79–82. doi:10.1515/BC.2008.005
   Web of Science ®Google Scholar
• Yang K, Dong W. SIRT1-related signaling pathways and their association with bronchopulmonary dysplasia. Front Med. 2021;8:595634. doi:10.3389/fmed.2021.595634
   Web of Science ®Google Scholar
• Man AWC, Li H, Xia N. The role of Sirtuin1 in regulating endothelial function, arterial remodeling and vascular aging. Front Physiol. 2019;10:1173.
   PubMed Web of Science ®Google Scholar
• Lee Y, Im E. Regulation of miRNAs by natural antioxidants in cardiovascular diseases: focus on SIRT1 and eNOS. Antioxidants. 2021;10(3):377.
   Web of Science ®Google Scholar
• Capece D, Verzella D, Flati I, et al. NF-kappaB: blending metabolism, immunity, and inflammation. Trends Immunol. 2022;43(9):757–775. doi:10.1016/j.it.2022.07.004
   PubMed Web of Science ®Google Scholar
• Blackwell TS, Hipps AN, Yamamoto Y, et al. NF-kappaB signaling in fetal lung macrophages disrupts airway morphogenesis. J Immunol. 2011;187(5):2740–2747. doi:10.4049/jimmunol.1101495
   Web of Science ®Google Scholar
• Ramani VC, Vlodavsky I, Ng M, et al. Chemotherapy induces expression and release of heparanase leading to changes associated with an aggressive tumor phenotype. Matrix Biol. 2016;55:22–34. doi:10.1016/j.matbio.2016.03.006
   PubMed Web of Science ®Google Scholar
• Ye Y, Zhang HW, Mei HX, et al. PDX regulates inflammatory cell infiltration via resident macrophage in LPS-induced lung injury. J Cell Mol Med. 2020;24(18):10604–10614. doi:10.1111/jcmm.15679
   Web of Science ®Google Scholar
• Zhuo XJ, Hao Y, Cao F, et al. Protectin DX increases alveolar fluid clearance in rats with lipopolysaccharide-induced acute lung injury. Exp Mol Med. 2018;50:1–13. doi:10.1038/s12276-018-0075-4
   Web of Science ®Google Scholar
• Liang ZJ, Wu QP, Chen BT, et al. Postnatal hyperoxia or DEHP exposure leads to growth restriction and delayed lung development in newborn rats. Pediatr Neonatol. 2018;59(1):24–30. doi:10.1016/j.pedneo.2016.11.002
   PubMed Web of Science ®Google Scholar
• Teng RJ, Jing X, Michalkiewicz T, et al. Attenuation of endoplasmic reticulum stress by caffeine ameliorates hyperoxia-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2017;312(5):L586–L98. doi:10.1152/ajplung.00405.2016
   PubMed Web of Science ®Google Scholar
• Ihrcke NS, Wrenshall LE, Lindman BJ, et al. Role of heparan sulfate in immune system-blood vessel interactions. Immunol Today. 1993;14(10):500–505. doi:10.1016/0167-5699(93)90265-M
   Google Scholar
• Rizzo AN, Haeger SM, Oshima K, et al. Alveolar epithelial glycocalyx degradation mediates surfactant dysfunction and contributes to acute respiratory distress syndrome. JCI Insight. 2022;7(2). doi:10.1172/jci.insight.154573
   Web of Science ®Google Scholar
• Couchman JR. Syndecans: proteoglycan regulators of cell-surface microdomains? Nat Rev Mol Cell Biol. 2003;4(12):926–937. doi:10.1038/nrm1257
   PubMed Web of Science ®Google Scholar
• Brauer R, Ge L, Schlesinger SY, et al. Syndecan-1 attenuates lung injury during influenza infection by potentiating c-Met signaling to suppress epithelial apoptosis. Am J Respir Crit Care Med. 2016;194(3):333–344. doi:10.1164/rccm.201509-1878OC
   Web of Science ®Google Scholar
• Dong W, Zhu X, Liu X, et al. Role of the SENP1-SIRT1 pathway in hyperoxia-induced alveolar epithelial cell injury. Free Radic Biol Med. 2021;173:142–150. doi:10.1016/j.freeradbiomed.2021.07.027
   PubMed Web of Science ®Google Scholar
• Mody K, Saslow JG, Kathiravan S, et al. Sirtuin1 in tracheal aspirate leukocytes: possible role in the development of bronchopulmonary dysplasia in premature infants. J Matern Fetal Neonatal Med. 2012;25(8):1483–1487. doi:10.3109/14767058.2011.645925
   PubMed Web of Science ®Google Scholar
• Kauppinen A, Suuronen T, Ojala J, et al. Antagonistic crosstalk between NF-kappaB and SIRT1 in the regulation of inflammation and metabolic disorders. Cell Signal. 2013;25(10):1939–1948. doi:10.1016/j.cellsig.2013.06.007
   PubMed Web of Science ®Google Scholar
• Edwards JR, Perrien DS, Fleming N, et al. Silent information regulator (Sir)T1 inhibits NF-kappaB signaling to maintain normal skeletal remodeling. J Bone Mineral Res. 2013;28(4):960–969. doi:10.1002/jbmr.1824
   PubMed Web of Science ®Google Scholar
• Hao NB, Tang B, Wang GZ, et al. Hepatocyte growth factor (HGF) upregulates heparanase expression via the PI3K/Akt/NF-kappaB signaling pathway for gastric cancer metastasis. Cancer Lett. 2015;361(1):57–66. doi:10.1016/j.canlet.2015.02.043
   PubMed Web of Science ®Google Scholar