circHECTD1 Promotes the Proliferation and Migration of Human Brain Vascular Smooth Muscle Cells via Interacting with KHDRBS3 to Stabilize EZH2 mRNA Expression

References

• Herrington W, Lacey B, Sherliker P, et al. Epidemiology of atherosclerosis and the potential to reduce the global burden of atherothrombotic disease. Circ Res. 2016;118(4):535–546. doi:10.1161/CIRCRESAHA.115.307611
   PubMed Web of Science ®Google Scholar
• Grootaert MOJ, Bennett MR. Vascular smooth muscle cells in atherosclerosis: time for a re-assessment. Cardiovasc Res. 2021;117(11):2326–2339. doi:10.1093/cvr/cvab046
   PubMed Web of Science ®Google Scholar
• Grootaert MOJ, Moulis M, Roth L, et al. Vascular smooth muscle cell death, autophagy and senescence in atherosclerosis. Cardiovasc Res. 2018;114(4):622–634. doi:10.1093/cvr/cvy007
   PubMed Web of Science ®Google Scholar
• Wu M-Y, Li C-J, Hou M-F, et al. New insights into the role of inflammation in the pathogenesis of atherosclerosis. Int J Mol Sci. 2017;18(10):2034. doi:10.3390/ijms18102034
   PubMed Web of Science ®Google Scholar
• Wang Z, Liu B, Zhu J, et al. Nicotine-mediated autophagy of vascular smooth muscle cell accelerates atherosclerosis via nAChRs/ROS/NF-kappaB signaling pathway. Atherosclerosis. 2019;284:1–10. doi:10.1016/j.atherosclerosis.2019.02.008
   PubMed Web of Science ®Google Scholar
• Rader DJ, Daugherty A. Translating molecular discoveries into new therapies for atherosclerosis. Nature. 2008;451(7181):904–913. doi:10.1038/nature06796
   PubMed Web of Science ®Google Scholar
• Kristensen LS, Andersen MS, Stagsted LVW, et al. The biogenesis, biology and characterization of circular RNAs. Nat Rev Genet. 2019;20(11):675–691. doi:10.1038/s41576-019-0158-7
   PubMed Web of Science ®Google Scholar
• Chen G, Tang W, Wang S, et al. Promising diagnostic and therapeutic circRNAs for skeletal and chondral disorders. Int J Biol Sci. 2021;17(5):1428–1439. doi:10.7150/ijbs.57887
   PubMed Web of Science ®Google Scholar
• Abi A, Farahani N, Molavi G, et al. Circular RNAs: epigenetic regulators in cancerous and noncancerous skin diseases. Cancer Gene Ther. 2020;27(5):280–293. doi:10.1038/s41417-019-0130-x
   PubMedGoogle Scholar
• Wang L, Xu GE, Spanos M, et al. Circular RNAs in cardiovascular diseases. Adv Exp Med Biol. 2018;1087:191–204.
   PubMedGoogle Scholar
• Huang A, Zheng H, Wu Z, et al. Circular RNA-protein interactions: functions, mechanisms, and identification. Theranostics. 2020;10(8):3503–3517. doi:10.7150/thno.42174
   PubMed Web of Science ®Google Scholar
• van Zonneveld AJ, Kölling M, Bijkerk R, et al. Circular RNAs in kidney disease and cancer. Nat Rev Nephrol. 2021;17(12):814–826. doi:10.1038/s41581-021-00465-9
   PubMed Web of Science ®Google Scholar
• Tao M, Zheng M, Xu Y, et al. CircRNAs and their regulatory roles in cancers. Mol Med. 2021;27(1):94. doi:10.1186/s10020-021-00359-3
   PubMed Web of Science ®Google Scholar
• Chen J, Yang J, Fei X, et al. CircRNA ciRS-7: a novel oncogene in multiple cancers. Int J Biol Sci. 2021;17(1):379–389. doi:10.7150/ijbs.54292
   PubMedGoogle Scholar
• Huang X, Zhao Y, Zhou H, et al. Circular RNAs in atherosclerosis. Clin Chim Acta. 2022;531:71–80. doi:10.1016/j.cca.2022.03.016
   PubMedGoogle Scholar
• Ding Y, Lu C, Zhang W, et al. The emerging role of circular RNAs in cardiovascular diseases. J Physiol Biochem. 2021;77(3):343–353. doi:10.1007/s13105-021-00807-y
   PubMed Web of Science ®Google Scholar
• Yang L, Yang F, Zhao H, et al. Circular RNA circCHFR facilitates the proliferation and migration of vascular smooth muscle via miR-370/FOXO1/Cyclin D1 pathway. Mol Ther Nucleic Acids. 2019;16:434–441. doi:10.1016/j.omtn.2019.02.028
   PubMedGoogle Scholar
• Si X, Zheng H, Wei G, et al. circRNA Hipk3 induces cardiac regeneration after myocardial infarction in mice by binding to Notch1 and miR-133a. Mol Ther Nucleic Acids. 2020;21:636–655. doi:10.1016/j.omtn.2020.06.024
   PubMedGoogle Scholar
• Kong P, Yu Y, Wang L, et al. circ-Sirt1 controls NF-κB activation via sequence-specific interaction and enhancement of SIRT1 expression by binding to miR-132/212 in vascular smooth muscle cells. Nucleic Acids Res. 2019;47(7):3580–3593. doi:10.1093/nar/gkz141
   PubMed Web of Science ®Google Scholar
• Qi X, Zhang D-H, Wu N, et al. ceRNA in cancer: possible functions and clinical implications. J Med Genet. 2015;52(10):710–718. doi:10.1136/jmedgenet-2015-103334
   PubMed Web of Science ®Google Scholar
• Zhang M, Bai X, Zeng X, et al. circRNA-miRNA-mRNA in breast cancer. Clin Chim Acta. 2021;523:120–130. doi:10.1016/j.cca.2021.09.013
   PubMed Web of Science ®Google Scholar
• Li B, Zhu L, Lu C, et al. circNDUFB2 inhibits non-small cell lung cancer progression via destabilizing IGF2BPs and activating anti-tumor immunity. Nat Commun. 2021;12(1):295. doi:10.1038/s41467-020-20527-z
   PubMed Web of Science ®Google Scholar
• Garikipati VNS, Verma SK, Cheng Z, et al. Circular RNA CircFndc3b modulates cardiac repair after myocardial infarction via FUS/VEGF-A axis. Nat Commun. 2019;10(1):4317. doi:10.1038/s41467-019-11777-7
   PubMed Web of Science ®Google Scholar
• Fang S, Guo H, Cheng Y, et al. circHECTD1 promotes the silica-induced pulmonary endothelial-mesenchymal transition via HECTD1. Cell Death Dis. 2018;9(3):396. doi:10.1038/s41419-018-0432-1
   PubMedGoogle Scholar
• Li C, Liu Y, Lv Z, et al. Circular RNA circHECTD1 facilitates glioma progression by regulating the miR-296-3p/SLC10A7 axis. J Cell Physiol. 2021;236(8):5953–5965. doi:10.1002/jcp.30277
   PubMedGoogle Scholar
• Cai J, Chen Z, Wang J, et al. circHECTD1 facilitates glutaminolysis to promote gastric cancer progression by targeting miR-1256 and activating beta-catenin/c-Myc signaling. Cell Death Dis. 2019;10(8):576. doi:10.1038/s41419-019-1814-8
   PubMedGoogle Scholar
• Bouguerra SA, Bourdillon MC, Dahmani Y, et al. Non insulin dependent diabetes in sand rat (Psammomys obesus) and production of collagen in cultured aortic smooth muscle Cells. Influence of insulin. Int J Exp Diabetes Res. 2001;2(1):37–46. doi:10.1155/EDR.2001.37
   PubMedGoogle Scholar
• Ruan C, Lu J, Wang H, et al. miR-26b-5p regulates hypoxia-induced phenotypic switching of vascular smooth muscle cells via the TGF-beta/Smad4 signaling pathway. Mol Med Rep. 2017;15(6):4185–4190. doi:10.3892/mmr.2017.6509
   PubMedGoogle Scholar
• Zang J, Lu D, Xu A. The interaction of circRNAs and RNA binding proteins: an important part of circRNA maintenance and function. J Neurosci Res. 2020;98(1):87–97. doi:10.1002/jnr.24356
   PubMed Web of Science ®Google Scholar
• Wu X, Qiu L, Feng H, et al. KHDRBS3 promotes paclitaxel resistance and induces glycolysis through modulated MIR17HG/CLDN6 signaling in epithelial ovarian cancer. Life Sci. 2022;293:120328. doi:10.1016/j.lfs.2022.120328
   PubMedGoogle Scholar
• Wu P, Gao Y, Shen S, et al. KHDRBS3 regulates the permeability of blood-tumor barrier via cDENND4C/miR-577 axis. Cell Death Dis. 2019;10(7):536. doi:10.1038/s41419-019-1771-2
   PubMedGoogle Scholar
• Miao R, Qi C, Fu Y, et al. Silencing of circARHGAP12 inhibits the progression of atherosclerosis via miR-630/EZH2/TIMP2 signal axis. J Cell Physiol. 2022;237(1):1057–1069. doi:10.1002/jcp.30598
   PubMedGoogle Scholar
• Bennett MR, Sinha S, Owens GK. Vascular smooth muscle cells in atherosclerosis. Circ Res. 2016;118(4):692–702. doi:10.1161/CIRCRESAHA.115.306361
   PubMed Web of Science ®Google Scholar
• Miano JM, Fisher EA, Majesky MW. Fate and state of vascular smooth muscle cells in atherosclerosis. Circulation. 2021;143(21):2110–2116. doi:10.1161/CIRCULATIONAHA.120.049922
   PubMed Web of Science ®Google Scholar
• Ding P, Ding Y, Tian Y, Lei X. Circular RNA circ_0010283 regulates the viability and migration of oxidized lowdensity lipoprotein induced vascular smooth muscle cells via an miR3703p/HMGB1 axis in atherosclerosis. Int J Mol Med. 2020;46(4):1399–1408. doi:10.3892/ijmm.2020.4703
   PubMed Web of Science ®Google Scholar
• Dong X, Hu H, Fang Z, et al. CTRP6 inhibits PDGF-BB-induced vascular smooth muscle cell proliferation and migration. Biomed Pharmacother. 2018;103:844–850. doi:10.1016/j.biopha.2018.04.112
   PubMed Web of Science ®Google Scholar
• Zheng S, Zhang X, Odame E, et al. CircRNA-protein interactions in muscle development and diseases. Int J Mol Sci. 2021;22(6):3262. doi:10.3390/ijms22063262
   PubMed Web of Science ®Google Scholar
• Wang Z, Lei X. Matrix factorization with neural network for predicting circRNA-RBP interactions. BMC Bioinform. 2020;21(1):229. doi:10.1186/s12859-020-3514-x
   PubMedGoogle Scholar
• Ukai S, Honma R, Sakamoto N, et al. Molecular biological analysis of 5-FU-resistant gastric cancer organoids; KHDRBS3 contributes to the attainment of features of cancer stem cell. Oncogene. 2020;39(50):7265–7278. doi:10.1038/s41388-020-01492-9
   PubMed Web of Science ®Google Scholar
• Mirzaei S, Gholami MH, Hushmandi K, et al. The long and short non-coding RNAs modulating EZH2 signaling in cancer. J Hematol Oncol. 2022;15(1):18. doi:10.1186/s13045-022-01235-1
   PubMed Web of Science ®Google Scholar
• Smith SA, Newby N, Bond B. Ending restenosis: inhibition of vascular smooth muscle cell proliferation by cAMP. Cells. 2019;8(11):1447. doi:10.3390/cells8111447
   PubMedGoogle Scholar
• Guan S, Tang Q, Liu W, et al. Nobiletin inhibits PDGF-BB-induced vascular smooth muscle cell proliferation and migration and attenuates neointimal hyperplasia in a rat carotid artery injury model. Drug Dev Res. 2014;75(8):489–496. doi:10.1002/ddr.21230
   PubMedGoogle Scholar
• Petsophonsakul P, Furmanik M, Forsythe R, et al. Role of vascular smooth muscle cell phenotypic switching and calcification in aortic aneurysm formation. Arterioscler Thromb Vasc Biol. 2019;39(7):1351–1368. doi:10.1161/ATVBAHA.119.312787
   PubMed Web of Science ®Google Scholar