FLI1 Regulates Histamine Decarboxylase Expression to Control Inflammation Signaling and Leukemia Progression

References

• Huang H, Li Y, Liang J, Finkelman FD. Molecular regulation of histamine synthesis. Front Immunol. 2018;9:1392. doi:10.3389/fimmu.2018.01392
   PubMed Web of Science ®Google Scholar
• Kennedy L, Hodges K, Meng F, Alpini G, Francis H. Histamine and histamine receptor regulation of gastrointestinal cancers. Transl Gastrointest Cancer. 2012;1(3):215–227.
   PubMedGoogle Scholar
• Thangam EB, Jemima EA, Singh H, et al. The role of histamine and histamine receptors in mast cell-mediated allergy and inflammation: the hunt for new therapeutic targets. Front Immunol. 2018;9:1873. doi:10.3389/fimmu.2018.01873
   PubMed Web of Science ®Google Scholar
• Höcker M, Zhang Z, Koh TJ, Wang TC. The regulation of histidine decarboxylase gene expression. Yale J Biol Med. 1996;69(1):21–33.
   PubMed Web of Science ®Google Scholar
• Medina VA, Rivera ES. Histamine receptors and cancer pharmacology. Br J Pharmacol. 2010;161(4):755–767. doi:10.1111/j.1476-5381.2010.00961.x
   PubMed Web of Science ®Google Scholar
• Ercan-Sencicek AG, Stillman AA, Ghosh AK, et al. L-histidine decarboxylase and Tourette’s syndrome. N Engl J Med. 2010;362(20):1901–1908.
   PubMed Web of Science ®Google Scholar
• Pittenger C. Histidine decarboxylase knockout mice as a model of the pathophysiology of Tourette syndrome and related conditions. Handb Exp Pharmacol. 2017;241:189–215. doi:10.1007/164-2016-127
   PubMedGoogle Scholar
• Ohtsu H, Tanaka S, Terui T, et al. Mice lacking histidine decarboxylase exhibit abnormal mast cells. FEBS Lett. 2001;502(1–2):53–56. doi:10.1016/s0014-5793(01)02663-1
   PubMed Web of Science ®Google Scholar
• Blaya B, Nicolau-Galmés F, Jangi SM, et al. Histamine and histamine receptor antagonists in cancer biology. Inflamm Allergy Drug Targets. 2010;9(3):146–157. doi:10.2174/187152810792231869
   PubMedGoogle Scholar
• Medina VA, Brenzoni PG, Lamas DJ, et al. Role of histamine H4 receptor in breast cancer cell proliferation. Front Biosci. 2011;3(3):1042–1060. doi:10.2741/e310
   Google Scholar
• Cricco G, Martin G, Labombarda F, Cocca C, Bergoc R, Rivera E. Human pancreatic carcinoma cell line Panc-I and the role of histamine in growth regulation. Inflamm Res. 2000;49(Suppl 1):S68–S69. doi:10.1007/PL00000188
   PubMedGoogle Scholar
• Cricco GP, Mohamad NA, Sambuco LA, et al. Histamine regulates pancreatic carcinoma cell growth through H3 and H4 receptors. Inflamm Res. 2008;57(Suppl 1):S23–S24. doi:10.1007/s00011-007-0611-5
   PubMedGoogle Scholar
• Grauers Wiktorin H, Nilsson MS, Kiffin R, et al. Histamine targets myeloid-derived suppressor cells and improves the anti-tumor efficacy of PD-1/PD-L1 checkpoint blockade. Cancer Immunol Immunother. 2019;68(2):163–174. doi:10.1007/s00262-018-2253-6
   PubMed Web of Science ®Google Scholar
• Stadtmauer EA. Histamine dihydrochloride and interleukin-2 in the treatment of acute myeloid leukemia. Semin Oncol. 2002;29(3 Suppl 7):47–51. doi:10.1053/sonc.2002.33084
   PubMed Web of Science ®Google Scholar
• Ben-David Y, Giddens EB, Bernstein A. Identification and mapping of a common proviral integration site Fli-1 in erythroleukemia cells induced by Friend murine leukemia virus. Proc Natl Acad Sci USA. 1990;87(4):1332–1336. doi:10.1073/pnas.87.4.1332
   PubMed Web of Science ®Google Scholar
• Ben-David Y, Giddens EB, Letwin K, Bernstein A. Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1. Genes Dev. 1991;5(6):908–918. doi:10.1101/gad.5.6.908
   PubMed Web of Science ®Google Scholar
• Ben-David Y, Gajendran B, Sample KM, Zacksenhaus E. Current insights into the role of Fli-1 in hematopoiesis and malignant transformation. Cell Mol Life Sci. 2022;79(3):163. doi:10.1007/s00018-022-04160-1
   PubMed Web of Science ®Google Scholar
• Cui JW, Vecchiarelli-Federico LM, Li YJ, Wang GJ, Ben-David Y. Continuous Fli-1 expression plays an essential role in the proliferation and survival of F-MuLV-induced erythroleukemia and human erythroleukemia. Leukemia. 2009;23(7):1311–1319. doi:10.1038/leu.2009.2
   PubMed Web of Science ®Google Scholar
• Wang C, Sample KM, Gajendran B, et al. FLI1 induces megakaryopoiesis gene expression through WAS/WIP-dependent and independent mechanisms; implications for Wiskott-Aldrich syndrome. Front Immunol. 2021;12:607836. doi:10.3389/fimmu.2021.607836
   PubMed Web of Science ®Google Scholar
• Liu T, Xia L, Yao Y, et al. Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis. Cell Death Dis. 2019;10(2):117. doi:10.1038/s41419-019-1363-1
   PubMedGoogle Scholar
• Liu T, Yao Y, Zhang G, et al. A screen for Fli-1 transcriptional modulators identifies PKC agonists that induce erythroid to megakaryocytic differentiation and suppress leukemogenesis. Oncotarget. 2017;8(10):16728–16743. doi:10.18632/oncotarget.14377
   PubMedGoogle Scholar
• Langtry HD, Grant SM, Goa KL. Famotidine. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in peptic ulcer disease and other allied diseases. Drugs. 1989;38(4):551–590. doi:10.2165/00003495-198938040-00005
   PubMed Web of Science ®Google Scholar
• Yamashita K, Suzuki Y, Matsui T, et al. Epigallocatechin gallate inhibits histamine release from rat basophilic leukemia (RBL-2H3) cells: role of tyrosine phosphorylation pathway. Biochem Biophys Res Commun. 2000;274(3):603–608. doi:10.1006/bbrc.2000.3200
   PubMed Web of Science ®Google Scholar
• Li Y, Liu B, Harmacek L, et al. The transcription factors GATA2 and microphthalmia-associated transcription factor regulate Hdc gene expression in mast cells and are required for IgE/mast cell-mediated anaphylaxis. J Allergy Clin Immunol. 2018;142(4):1173–1184. doi:10.1016/j.jaci.2017.10.043
   PubMed Web of Science ®Google Scholar
• Fricker M, Gibson PG, Powell H, et al. A sputum 6-gene signature predicts future exacerbations of poorly controlled asthma. J Allergy Clin Immunol. 2019;144(1):51–60. doi:10.1016/j.jaci.2018.12.1020
   PubMed Web of Science ®Google Scholar
• Chen B, Sheng D, Wang C, et al. FLI1 regulates inflammation-associated genes to accelerate leukemogenesis. Cell Signal. 2022;92:110269. doi:10.1016/j.cellsig.2022.110269
   PubMed Web of Science ®Google Scholar
• Dougherty RH, Sidhu SS, Raman K, et al. Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma. J Allergy Clin Immunol. 2010;125(5):1046–1053. doi:10.1016/j.jaci.2010.03.003
   PubMed Web of Science ®Google Scholar
• Takabayashi T, Kato A, Peters AT, et al. Glandular mast cells with distinct phenotype are highly elevated in chronic rhinosinusitis with nasal polyps. J Allergy Clin Immunol. 2012;130(2):410–420. doi:10.1016/j.jaci.2012.02.046
   PubMed Web of Science ®Google Scholar
• Teh BS, Seow WK, Chalmers AH, Playford S, Ioannoni B, Thong YH. Inhibition of histamine release from rat mast cells by the plant alkaloid tetrandrine. Int Arch Allergy Appl Immunol. 1988;86(2):220–224. doi:10.1159/000234575
   PubMedGoogle Scholar
• Bharti R, Dey G, Ojha PK, et al. Diacerein-mediated inhibition of IL-6/IL-6R signaling induces apoptotic effects on breast cancer. Oncogene. 2016;35(30):3965–3975. doi:10.1038/onc.2015.466
   PubMed Web of Science ®Google Scholar
• Pasin JS, Ferreira AP, Saraiva AL, et al. Diacerein decreases TNF-alpha and IL-1beta levels in peritoneal fluid and prevents Baker’s yeast-induced fever in young rats. Inflamm Res. 2010;59(3):189–196. doi:10.1007/s00011-009-0085-8
   PubMed Web of Science ®Google Scholar
• Mohan GC, Zhang H, Bao L, Many B, Chan LS. Diacerein inhibits the pro-atherogenic & pro-inflammatory effects of IL-1 on human keratinocytes & endothelial cells. PLoS One. 2017;12(3):e0173981. doi:10.1371/journal.pone.0173981
   PubMed Web of Science ®Google Scholar
• Takahashi K, Tanaka S, Furuta K, Ichikawa A. Histamine H(2) receptor-mediated modulation of local cytokine expression in a mouse experimental tumor model. Biochem Biophys Res Commun. 2002;297(5):1205–1210. doi:10.1016/s0006-291x(02)02360-4
   PubMed Web of Science ®Google Scholar
• Yan Z, Liu L, Jiao L, Wen X, Liu J, Wang N. Bioinformatics analysis and identification of underlying biomarkers potentially linking allergic rhinitis and asthma. Med Sci Monit. 2020;26:e924934. doi:10.12659/MSM.924934
   PubMed Web of Science ®Google Scholar
• Zhao X, Younis S, Shi H, et al. RNA-seq characterization of histamine-releasing mast cells as potential therapeutic target of osteoarthritis. Clin Immunol. 2022;244:109117. doi:10.1016/j.clim.2022.109117
   PubMed Web of Science ®Google Scholar
• Percie du Sert N, Hurst V, Ahluwalia A, et al. The ARRIVE guidelines 2.0: updated guidelines for reporting animal research. BMC Vet Res. 2020;16(1):242. doi:10.1186/s12917-020-02451-y
   PubMed Web of Science ®Google Scholar