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ORIGINAL RESEARCH

Platelet-to-Lymphocyte Ratio (PLR) as the Prognostic Factor for Recurrence/Residual Disease in HSIL Patients After LEEP

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Pages 1923-1936 | Received 08 Feb 2023, Accepted 19 Apr 2023, Published online: 01 May 2023

References

  • Sung H, Ferlay J, Siegel RL., et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71(3):209–249. doi:10.3322/caac.21660
  • Alrajjal A, Pansare V, Choudhury MSR, Khan MYA, Shidham VB. Squamous intraepithelial lesions (SIL: LSIL, HSIL, ASCUS, ASC-H, LSIL-H) of Uterine Cervix and Bethesda System. Cytojournal. 2021;18:16. doi:10.25259/Cytojournal_24_2021
  • Perkins RB, Guido RS, Castle PE, et al. 2019 ASCCP Risk-Based Management Consensus Guidelines for Abnormal Cervical Cancer Screening Tests and Cancer Precursors. J Low Genit Tract Dis. 2020;24(2):102–131. doi:10.1097/LGT.0000000000000525
  • Insinga RP, Glass AG, Rush BB. Diagnoses and outcomes in cervical cancer screening: a population-based study. Am J Obstet Gynecol. 2004;191(1):105–113. doi:10.1016/j.ajog.2004.01.043
  • Castle PE, Schiffman M, Wheeler CM, et al. Evidence for frequent regression of cervical intraepithelial neoplasia-grade 2. Obstet Gynecol. 2009;113(1):18–25. doi:10.1097/AOG.0b013e31818f5008
  • Ostör AG. Natural history of cervical intraepithelial neoplasia: a critical review. Int J Gynecol Pathol. 1993;12(2):186–192. doi:10.1097/00004347-199304000-00018
  • Chen W, Zheng R, Baade PD, et al. Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66(2):115–132. doi:10.3322/caac.21338
  • D’Alessandro P, Arduino B, Borgo M, et al. Loop Electrosurgical Excision Procedure versus Cryotherapy in the Treatment of Cervical Intraepithelial Neoplasia: a Systematic Review and Meta-Analysis of Randomized Controlled Trials. Gynecol Minim Invasive Ther. 2018;7(4):145–151. doi:10.4103/GMIT.GMIT_56_18
  • Santesso N, Mustafa RA, Wiercioch W, et al. Systematic reviews and meta-analyses of benefits and harms of cryotherapy, LEEP, and cold knife conization to treat cervical intraepithelial neoplasia. Int J Gynaecol Obstet. 2016;132(3):266–271. doi:10.1016/j.ijgo.2015.07.026
  • Sun P, Song Y, Ruan G, et al. Clinical validation of the PCR-reverse dot blot human papillomavirus genotyping test in cervical lesions from Chinese women in the Fujian province: a hospital-based population study. J Gynecol Oncol. 2017;28(5):e50. doi:10.3802/jgo.2017.28.e50
  • Chen L, Dong B, Zhang Q, et al. HR-HPV viral load quality detection provide more accurate prediction for residual lesions after treatment: a prospective cohort study in patients with high-grade squamous lesions or worse. Med Oncol. 2020;37(5):37. doi:10.1007/s12032-020-01363-z
  • Kalogirou D, Antoniou G, Karakitsos P, et al. Predictive factors used to justify hysterectomy after loop conization: increasing age and severity of disease. Eur J Gynaecol Oncol. 1997;18(2):113–116.
  • Arbyn M, Redman CWE, Verdoodt F, et al. Incomplete excision of cervical precancer as a predictor of treatment failure: a systematic review and meta-analysis. Lancet Oncol. 2017;18(12):1665–1679. doi:10.1016/S1470-2045(17)30700-3
  • Kao SC, Pavlakis N, Harvie R, et al. High blood neutrophil-to-lymphocyte ratio is an indicator of poor prognosis in malignant mesothelioma patients undergoing systemic therapy. Clin Cancer Res. 2010;16(23):5805–5813. doi:10.1158/1078-0432.CCR-10-2245
  • Diem S, Schmid S, Krapf M, et al. Neutrophil-to-Lymphocyte ratio (NLR) and Platelet-to-Lymphocyte ratio (PLR) as prognostic markers in patients with non-small cell lung cancer (NSCLC) treated with nivolumab. Lung Cancer. 2017;111:176–181. doi:10.1016/j.lungcan.2017.07.024
  • Zhu M, Feng M, He F, et al. Pretreatment neutrophil-lymphocyte and platelet-lymphocyte ratio predict clinical outcome and prognosis for cervical Cancer. Clin Chim Acta. 2018;483:296–302. doi:10.1016/j.cca.2018.05.025
  • Han X, Liu S, Yang G, et al. Prognostic value of systemic hemato-immunological indices in uterine cervical cancer: a systemic review, meta-analysis, and meta-regression of observational studies. Gynecol Oncol. 2021;160(1):351–360. doi:10.1016/j.ygyno.2020.10.011
  • Xu M, Wu Q, Cai L, Sun X, Xie X, Sun P. Systemic Inflammatory Score predicts Overall Survival in patients with Cervical Cancer. J Cancer. 2021;12(12):3671–3677. doi:10.7150/jca.56170
  • Tas M, Yavuz A, Ak M, et al. Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Discriminating Precancerous Pathologies from Cervical Cancer. J Oncol. 2019;2019:2476082. doi:10.1155/2019/2476082
  • Barnes PW, McFadden SL, Machin SJ, Simson E. The international consensus group for hematology review: suggested criteria for action following automated CBC and WBC differential analysis. Lab Hematol. 2005;11(2):83–90. doi:10.1532/LH96.05019
  • Solomon D, Davey D, Kurman R, et al. The 2001 Bethesda System: terminology for reporting results of cervical cytology. JAMA. 2002;287(16):2114–2119. doi:10.1001/jama.287.16.2114
  • Apgar BS, Zoschnick L, Wright TC. The 2001 Bethesda System terminology. Am Fam Physician. 2003;68(10):1992–1998.
  • Reich O, Regauer S, Marth C, et al. Precancerous Lesions of the Cervix, Vulva and Vagina According to the 2014 WHO Classification of Tumors of the Female Genital Tract. Geburtshilfe Frauenheilkd. 2015;75(10):1018–1020. doi:10.1055/s-0035-1558052
  • Waxman AG, Chelmow D, Darragh TM, et al. Revised terminology for cervical histopathology and its implications for management of high-grade squamous intraepithelial lesions of the cervix. Obstet Gynecol. 2012;120(6):1465–1471. doi:10.1097/AOG.0b013e31827001d5
  • Kang Y, Sun P, Mao X, et al. PCR-reverse dot blot human papillomavirus genotyping as a primary screening test for cervical cancer in a hospital-based cohort. J Gynecol Oncol. 2019;30(3):e29. doi:10.3802/jgo.2019.30.e29
  • Hoffman SR, Le T, Lockhart A, et al. Patterns of persistent HPV infection after treatment for cervical intraepithelial neoplasia (CIN): a systematic review. Int J Cancer. 2017;141(1):8–23. doi:10.1002/ijc.30623
  • Feliciano EMC, Kroenke CH, Meyerhardt JA, et al. Association of Systemic Inflammation and Sarcopenia With Survival in Nonmetastatic Colorectal Cancer: results From the C SCANS Study. JAMA Oncol. 2017;3(12):e172319. doi:10.1001/jamaoncol.2017.2319
  • Nishida J, Momoi Y, Miyakuni K, et al. Epigenetic remodelling shapes inflammatory renal cancer and neutrophil-dependent metastasis. Nat Cell Biol. 2020;22(4):465–475. doi:10.1038/s41556-020-0491-2
  • Zhang HY, Xie HL, Ruan GT, et al. Lymphocyte to C-reactive protein ratio could better predict the prognosis of patients with stage IV cancer. BMC Cancer. 2022;22(1):1080. doi:10.1186/s12885-022-10145-x
  • Chao B, Ju X, Zhang L, Xu X, Zhao Y. A Novel Prognostic Marker Systemic Inflammation Response Index (SIRI) for Operable Cervical Cancer Patients. Front Oncol. 2020;10:766. doi:10.3389/fonc.2020.00766
  • Huang H, Liu Q, Zhu L, et al. Prognostic Value of Preoperative Systemic Immune-Inflammation Index in Patients with Cervical Cancer. Sci Rep. 2019;9(1):3284. doi:10.1038/s41598-019-39150-0
  • Lei H, Xu S, Mao X, et al. Systemic Immune-Inflammatory Index as a Predictor of Lymph Node Metastasis in Endometrial Cancer. J Inflamm Res. 2021;14:7131–7142. doi:10.2147/JIR.S345790
  • Chun S, Shin K, Kim KH, et al. The Neutrophil-Lymphocyte Ratio Predicts Recurrence of Cervical Intraepithelial Neoplasia. J Cancer. 2017;8(12):2205–2211. doi:10.7150/jca.19173
  • Diakos CI, Charles KA, McMillan DC, et al. Cancer-related inflammation and treatment effectiveness. Lancet Oncol. 2014;15(11):e493–503. doi:10.1016/S1470-2045(14)70263-3
  • Hammes LS, Tekmal RR, Naud P, et al. Macrophages, inflammation and risk of cervical intraepithelial neoplasia (CIN) progression--clinicopathological correlation. Gynecol Oncol. 2007;105(1):157–165. doi:10.1016/j.ygyno.2006.11.023
  • Long T, Long L, Chen Y, et al. Severe cervical inflammation and high-grade squamous intraepithelial lesions: a cross-sectional study. Arch Gynecol Obstet. 2021;303(2):547–556. doi:10.1007/s00404-020-05804-y
  • Proctor MJ, Morrison DS, Talwar D, et al. A comparison of inflammation-based prognostic scores in patients with cancer. A Glasgow Inflammation Outcome Study. Eur J Cancer. 2011;47(17):2633–2641. doi:10.1016/j.ejca.2011.03.028
  • Farzaneh F, Faghih N, Hosseini MS, et al. Evaluation of Neutrophil-Lymphocyte Ratio as a Prognostic Factor in Cervical Intraepithelial Neoplasia Recurrence. Asian Pac J Cancer Prev. 2019;20(8):2365–2372. doi:10.31557/APJCP.2019.20.8.2365
  • Bilir F, Chkhikvadze M, Yilmaz AY, et al. Prognostic value of systemic inflammation response index in patients with persistent human papilloma virus infection. Ginekol Pol. 2022;93(9):705–709. doi:10.5603/GP.a2021.0200
  • Brewczyński A, Jabłońska B, Mazurek AM, et al. Comparison of Selected Immune and Hematological Parameters and Their Impact on Survival in Patients with HPV-Related and HPV-Unrelated Oropharyngeal Cancer. Cancers. 2021;13(13):3256. doi:10.3390/cancers13133256
  • Rabinowich H, Cohen R, Bruderman I, et al. Functional analysis of mononuclear cells infiltrating into tumors: lysis of autologous human tumor cells by cultured infiltrating lymphocytes. Cancer Res. 1987;47(1):173–177.
  • D’Agostino M, Di Cecco M, Marani C, et al. Positive Linear Relationship between Nucleophosmin Protein Expression and the Viral Load in HPV-Associated Oropharyngeal Squamous Cell Carcinoma: a Possible Tool for Stratification of Patients. Int J Mol Sci. 2023;24(4):3482. doi:10.3390/ijms24043482
  • Somineni HK, Venkateswaran S, Kilaru V, et al. Blood-Derived DNA Methylation Signatures of Crohn’s Disease and Severity of Intestinal Inflammation. Gastroenterology. 2019;156(8):2254–2265.e2253. doi:10.1053/j.gastro.2019.01.270
  • Tomlinson MS, Bommarito PA, Martin EM, et al. Microorganisms in the human placenta are associated with altered CpG methylation of immune and inflammation-related genes. PLoS One. 2017;12(12):e0188664. doi:10.1371/journal.pone.0188664
  • Fu K, Lei M, Wu LS, et al. Triage by PAX1 and ZNF582 Methylation in Women With Cervical Intraepithelial Neoplasia Grade 3: a Multicenter Case-Control Study. Open Forum Infect Dis. 2022;9(5):ofac013. doi:10.1093/ofid/ofac013
  • Li B, Guo R, Lai T, Qiao L, Fu H. The application of PAX1 methylation detection and HPV E6/E7 mRNA detection in cervical cancer screening. J Obstet Gynaecol Res. 2021;47(8):2720–2728. doi:10.1111/jog.14869
  • Giorgi Rossi P, Carozzi F, Ronco G, et al. p16/ki67 and E6/E7 mRNA Accuracy and Prognostic Value in Triaging HPV DNA-Positive Women. J Natl Cancer Inst. 2021;113(3):292–300. doi:10.1093/jnci/djaa105
  • Kühn JP, Schmid W, Körner S, et al. HPV Status as Prognostic Biomarker in Head and Neck Cancer-Which Method Fits the Best for Outcome Prediction? Cancers. 2021;13(18):4730. doi:10.3390/cancers13184730
  • He Q, Li L, Ren Q. The Prognostic Value of Preoperative Systemic Inflammatory Response Index (SIRI) in Patients With High-Grade Glioma and the Establishment of a Nomogram. Front Oncol. 2021;11:671811. doi:10.3389/fonc.2021.671811
  • Carr PL, Felsenstein D, Friedman RH. Evaluation and management of vaginitis. J Gen Intern Med. 1998;13(5):335–346. doi:10.1046/j.1525-1497.1998.00101.x
  • Wilson J. Management of bacterial vaginosis. Drug Ther Bull. 1998;36(5):33–35. doi:10.1136/dtb.1998.36533
  • Santella B, Schettino MT, Franci G, et al. Microbiota and HPV: the role of viral infection on vaginal microbiota. J Med Virol. 2022;94(9):4478–4484. doi:10.1002/jmv.27837
  • Dong B, Huang Y, Cai H, et al. Prevotella as the hub of the cervicovaginal microbiota affects the occurrence of persistent human papillomavirus infection and cervical lesions in women of childbearing age via host NF-κB/C-myc. J Med Virol. 2022;94(11):5519–5534. doi:10.1002/jmv.28001
  • Lin W, Zhang Q, Chen Y, et al. Changes of the vaginal microbiota in HPV infection and cervical intraepithelial neoplasia: a cross-sectional analysis. Sci Rep. 2022;12(1):2812. doi:10.1038/s41598-022-06731-5
  • Pek E, Beyazit F, Korkmaz NS. Predictive value of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Patients with Vaginitis. Pak J Med Sci. 2021;37(1):250–255. doi:10.12669/pjms.37.1.2774