Electroacupuncture Alleviates Lung Injury in CpG1826-Challenged Mice via Modulating CD39-NLRP3 Pathway

References

• Ahmar Rauf M, Nisar M, Abdelhady H, Gavande N, Iyer AK. Nanomedicine approaches to reduce cytokine storms in severe infections. Drug Discov Today. 2022;27(11):103355. doi:10.1016/j.drudis.2022.103355
   PubMed Web of Science ®Google Scholar
• Bonaventura A, Vecchié A, Dagna L, et al. Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19. Nat Rev Immunol. 2021;21(5):319–329. doi:10.1038/s41577-021-00536-9
   PubMed Web of Science ®Google Scholar
• Laurent P, Yang C, Rendeiro AF, et al. Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19. Sci Immunol. 2022;7(75):eadd4906. doi:10.1126/sciimmunol.add4906
   PubMed Web of Science ®Google Scholar
• Guan T, Zhou X, Zhou W, Lin H. Regulatory T cell and macrophage crosstalk in acute lung injury: future perspectives. Cell Death Discov. 2023;9(1):9. doi:10.1038/s41420-023-01310-7
   PubMed Web of Science ®Google Scholar
• Lin X, Fu B, Xiong Y, et al. Unconventional secretion of unglycosylated ORF8 is critical for the cytokine storm during SARS-CoV-2 infection. PLoS Pathog. 2023;19(1):e1011128. doi:10.1371/journal.ppat.1011128
   PubMed Web of Science ®Google Scholar
• Li W, Xu H, Shao J, et al. Discovery of alantolactone as a natural NLRP3 inhibitor to alleviate NLRP3-driven inflammatory diseases in mice. Br J Pharmacol. 2023;20. doi:10.1111/bph.16036
   Google Scholar
• Dubyak GR, Miller BA, Pearlman E. Pyroptosis in neutrophils: multimodal integration of inflammasome and regulated cell death signaling pathways. Immunol Rev. 2023;19. doi:10.1111/imr.13186
   Google Scholar
• Hsu CG, Li W, Sowden M, Chávez CL, Berk BC. Pnpt1 mediates NLRP3 inflammasome activation by MAVS and metabolic reprogramming in macrophages. Cell Mol Immunol. 2023;20(2):131–142. doi:10.1038/s41423-022-00962-2
   PubMed Web of Science ®Google Scholar
• Linden J, Koch-Nolte F, Dahl G. Purine release, metabolism, and signaling in the inflammatory response. Annu Rev Immunol. 2019;37:325–347. doi:10.1146/annurev-immunol-051116-052406
   PubMed Web of Science ®Google Scholar
• Liu J, Wang L-N. Neurogenic dysphagia in traditional Chinese medicine. Brain Behav. 2020;10(11):e01812. doi:10.1002/brb3.1812
   PubMed Web of Science ®Google Scholar
• Torres-Rosas R, Yehia G, Peña G, et al. Dopamine mediates vagal modulation of the immune system by electroacupuncture. Nat Med. 2014;20(3):291–295. doi:10.1038/nm.3479
   PubMed Web of Science ®Google Scholar
• Liu S, Wang Z-F, Su Y-S, et al. Somatotopic organization and intensity dependence in driving distinct NPY-expressing sympathetic pathways by electroacupuncture. Neuron. 2020;108(3):436–450.e7. doi:10.1016/j.neuron.2020.07.015
   PubMed Web of Science ®Google Scholar
• Weaver LK, Chu N, Behrens EM. Interferon-γ–mediated immunopathology potentiated by toll-like receptor 9 activation in a murine model of macrophage activation syndrome. Arthritis Rheumatol. 2019;71(1):161–168. doi:10.1002/art.40683
   PubMed Web of Science ®Google Scholar
• Shimazu H, Munakata S, Tashiro Y, et al. Pharmacological targeting of plasmin prevents lethality in a murine model of macrophage activation syndrome. Blood. 2017;130(1):59–72. doi:10.1182/blood-2016-09-738096
   PubMed Web of Science ®Google Scholar
• Yang L, Ding W, Dong Y, et al. Electroacupuncture attenuates surgical pain-induced delirium-like behavior in mice via remodeling gut microbiota and dendritic spine. Front Immunol. 2022;13:955581. doi:10.3389/fimmu.2022.955581
   PubMed Web of Science ®Google Scholar
• Ash MK, Bhimalli PP, Cho BK, et al. Bulk IgG glycosylation predicts COVID-19 severity and vaccine antibody response. Cell Rep. 2022;41(11):111799. doi:10.1016/j.celrep.2022.111799
   PubMed Web of Science ®Google Scholar
• Tang J, Zeng C, Cox TM, et al. Respiratory mucosal immunity against SARS-CoV-2 after mRNA vaccination. Sci Immunol. 2022;7(76):eadd4853. doi:10.1126/sciimmunol.add4853
   PubMed Web of Science ®Google Scholar
• Wu J, Lan Y, Shi X, et al. Sennoside A is a novel inhibitor targeting caspase-1. Food Funct. 2022;13(19):9782–9795. doi:10.1039/d2fo01730j
   PubMed Web of Science ®Google Scholar
• Behrens EM, Canna SW, Slade K, et al. Repeated TLR9 stimulation results in macrophage activation syndrome-like disease in mice. J Clin Invest. 2011;121(6):2264–2277. doi:10.1172/JCI43157
   PubMed Web of Science ®Google Scholar
• Tang S, Yang C, Li S, et al. Genetic and pharmacological targeting of GSDMD ameliorates systemic inflammation in macrophage activation syndrome. J Autoimmun. 2022;133:102929. doi:10.1016/j.jaut.2022.102929
   PubMed Web of Science ®Google Scholar
• Liu X, Fan T, Guan J, et al. Dopamine relieves inflammatory responses through the D2 receptor after electroacupuncture at ST36 in a mouse model of chronic obstructive pulmonary disease. Acupunct Med. 2023;41(3):163–174. doi:10.1177/09645284221107684
   PubMed Web of Science ®Google Scholar
• Liu XY, Su JC, Zhang XF, et al. Electroacupuncture preconditioning improves pulmonary function via inhibiting inflammatory response and up-regulating expression of ACE2 and Ang (1–7) in lipopolysaccharide-induced acute lung injury rats. Zhen Ci Yan Jiu. 2022;47(8):684–689. Chinese. doi:10.13702/j.1000-0607.20210979
   PubMedGoogle Scholar
• Huang D, Chen M, Wang Z, Hou L, Yu W. Electroacupuncture pretreatment attenuates inflammatory lung injury after cardiopulmonary bypass by suppressing NLRP3 inflammasome activation in rats. Inflammation. 2019;42(3):895–903. doi:10.1007/s10753-018-0944-y
   PubMed Web of Science ®Google Scholar
• Wu Y, Huang D, Wang X, et al. Suppression of NLRP3 inflammasome by Platycodin D via the TLR4/MyD88/NF-κB pathway contributes to attenuation of lipopolysaccharide induced acute lung injury in rats. Int Immunopharmacol. 2021;96:107621. doi:10.1016/j.intimp.2021.107621
   PubMed Web of Science ®Google Scholar
• Fajgenbaum DC, June CH. Cytokine Storm. N Engl J Med. 2020;383(23):2255–2273. doi:10.1056/NEJMra2026131
   PubMed Web of Science ®Google Scholar
• Chaturvedi V, Marsh RA, Zoref-Lorenz A, et al. T-cell activation profiles distinguish hemophagocytic lymphohistiocytosis and early sepsis. Blood. 2021;137(17):2337–2346. doi:10.1182/blood.2020009499
   PubMed Web of Science ®Google Scholar
• Arora H, Wilcox SM, Johnson LA, et al. The ATP-binding cassette gene ABCF1 functions as an E2 ubiquitin-conjugating enzyme controlling macrophage polarization to dampen lethal septic shock. Immunity. 2019;50(2):418–431.e6. doi:10.1016/j.immuni.2019.01.014
   PubMed Web of Science ®Google Scholar
• Camilli G, Blagojevic M, Naglik JR, Richardson JP. Programmed cell death: central player in fungal infections. Trends Cell Biol. 2021;31(3):179–196. doi:10.1016/j.tcb.2020.11.005
   PubMed Web of Science ®Google Scholar
• Wang Y, Zhang L, Zhou F. Cuproptosis: a new form of programmed cell death. Cell Mol Immunol. 2022;19(8):867–868. doi:10.1038/s41423-022-00866-1
   PubMed Web of Science ®Google Scholar
• Kajarabille N, Latunde-Dada GO. Programmed cell-death by ferroptosis: antioxidants as mitigators. Int J Mol Sci. 2019;20(19):4968. doi:10.3390/ijms20194968
   PubMed Web of Science ®Google Scholar
• Savio LEB, Robson SC, Longhi MS. Ectonucleotidase modulation of lymphocyte function in gut and liver. Front Cell Dev Biol. 2022;8:621760. doi:10.3389/fcell.2020.621760
   Web of Science ®Google Scholar
• Fu J, Wu H. Structural mechanisms of NLRP3 inflammasome assembly and activation. Annu Rev Immunol. 2023;41:301–316. doi:10.1146/annurev-immunol-081022-021207
   PubMed Web of Science ®Google Scholar
• Elias EE, Lyons B, Muruve DA. Gasdermins and pyroptosis in the kidney. Nat Rev Nephrol. 2023. doi:10.1038/s41581-022-00662-0
   PubMedGoogle Scholar
• Zhang T, Lu L, Li M, et al. Exosome from BMMSC attenuates cardiopulmonary bypass-induced acute lung injury via YAP/β-catenin pathway: downregulation of pyroptosis. Stem Cells. 2022;40(12):1122–1133. doi:10.1093/stmcls/sxac063
   PubMed Web of Science ®Google Scholar
• Lv ZY, Shi YL, Bassi GS, et al. Electroacupuncture at ST36 (Zusanli) prevents T-Cell lymphopenia and improves survival in septic mice. J Inflamm Res. 2022;15:2819–2833. doi:10.2147/JIR.S361466
   PubMed Web of Science ®Google Scholar
• Kong JT, Puetz C, Tian L, et al. Effect of electroacupuncture vs sham treatment on change in pain severity among adults with chronic low back pain: a randomized clinical trial. JAMA Netw Open. 2020;3(10):e2022787. doi:10.1001/jamanetworkopen.2020.22787
   PubMed Web of Science ®Google Scholar
• Zhou F, Jiang H, Kong N, et al. Electroacupuncture attenuated anxiety and depression-like behavior via inhibition of hippocampal inflammatory response and metabolic disorders in TNBS-induced IBD rats. Oxid Med Cell Longev. 2022;2022:8295580. doi:10.1155/2022/8295580
   PubMed Web of Science ®Google Scholar
• Jia YZ, Li HT, Zhang GM, et al. Electroacupuncture alleviates orofacial allodynia and anxiety-like behaviors by regulating synaptic plasticity of the CA1 hippocampal region in a mouse model of trigeminal neuralgia. Front Mol Neurosci. 2022;15:979483. doi:10.3389/fnmol.2022.979483
   PubMed Web of Science ®Google Scholar
• Yen CM, Wu TC, Hsieh CL, Huang YW, Lin YW. Distal electroacupuncture at the LI4 acupoint reduces CFA-induced inflammatory pain via the brain TRPV1 signaling pathway. Int J Mol Sci. 2019;20(18):4471. doi:10.3390/ijms20184471
   PubMed Web of Science ®Google Scholar
• Xu S, Yu L, Luo X, et al. Manual acupuncture versus sham acupuncture and usual care for prophylaxis of episodic migraine without aura: multicentre, randomised clinical trial. BMJ. 2020;368:m697. doi:10.1136/bmj.m697
   PubMed Web of Science ®Google Scholar
• Yu C, Shen F, Kong L, Wang X, Jiang T. Analysis of the current situation of sham acupuncture control in acupuncture animal experiments. J Tradition Chin Med. 2019;60:1509–1513. doi:10.13288/j.11-2166/r.2019.17.016
   Google Scholar