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ORIGINAL RESEARCH

Interactions of Fibroblast Subtypes Influence Osteoclastogenesis and Alveolar Bone Destruction in Periodontitis

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Pages 3143-3156 | Received 10 May 2023, Accepted 18 Jul 2023, Published online: 25 Jul 2023

References

  • Tonetti MS, Greenwell H, Kornman KS. Staging and grading of periodontitis: framework and proposal of a new classification and case definition. J Periodontol. 2018;89(Suppl 1):S159–S172. doi:10.1002/JPER.18-0006
  • Kindstedt E, Koskinen Holm C, Palmqvist P, Sjostrom M, Lejon K, Lundberg P. Innate lymphoid cells are present in gingivitis and periodontitis. J Periodontol. 2019;90:200–207. doi:10.1002/JPER.17-0750
  • Pihlstrom BL, Michalowicz BS, Johnson NW. Periodontal diseases. Lancet. 2005;366(9499):1809–1820. doi:10.1016/S0140-6736(05)67728-8
  • Kurgan S, Kantarci A. Molecular basis for immunohistochemical and inflammatory changes during progression of gingivitis to periodontitis. Periodontol 2000. 2018;76(1):51–67. doi:10.1111/prd.12146
  • Pei QG, Wang HC, Li L, Wang ZL. Triggering receptor expressed on myeloid cells-2 stimulates osteoclast differentiation and bone loss in periodontitis. Oral Dis. 2022;28:1652–1661. doi:10.1111/odi.14004
  • Mahanonda R, Champaiboon C, Subbalekha K, et al. Human memory B cells in healthy gingiva, gingivitis, and periodontitis. J Immunol. 2016;197(3):715–725. doi:10.4049/jimmunol.1600540
  • Busch S, Andersson D, Bom E, Walsh C, Stahlberg A, Landberg G. Cellular organization and molecular differentiation model of breast cancer-associated fibroblasts. Mol Cancer. 2017;16(1):73. doi:10.1186/s12943-017-0642-7
  • Lambrechts D, Wauters E, Boeckx B, et al. Phenotype molding of stromal cells in the lung tumor microenvironment. Nat Med. 2018;24(8):1277–1289. doi:10.1038/s41591-018-0096-5
  • Raz Y, Cohen N, Shani O, et al. Bone marrow-derived fibroblasts are a functionally distinct stromal cell population in breast cancer. J Exp Med. 2018;215:3075–3093. doi:10.1084/jem.20180818
  • Wang HC, Li TJ. The growth and osteoclastogenic effects of fibroblasts isolated from keratocystic odontogenic tumor. Oral Dis. 2013;19:162–168.
  • Wang HC, Jiang WP, Sima ZH, Li TJ. Fibroblasts isolated from a keratocystic odontogenic tumor promote osteoclastogenesis in vitro via interaction with epithelial cells. Oral Dis. 2015;21:170–177. doi:10.1111/odi.12231
  • Wang HC, Wang P, Chen YW, Zhang Y. Bevacizumab or fibronectin gene editing inhibits the osteoclastogenic effects of fibroblasts derived from human radicular cysts. Acta Pharmacol Sin. 2019;40:949–956. doi:10.1038/s41401-018-0172-x
  • Liu CY, Wang HC. The fibroblast of radicular cyst facilitate osteoclastogenesis via the autocrine of Fibronectin containing extra domain A. Oral Dis. 2019;25:1136–1146. doi:10.1111/odi.13064
  • Yang JW, Jiang JH, Wang HC, Li CY. The extra domain A of fibronectin facilitates osteoclastogenesis in radicular cysts through vascular endothelial growth factor. Int Endod J. 2020;53(4):478–491.
  • Yang J, Xu S, Wang HC. Heterogeneity of fibroblasts from radicular cyst influenced osteoclastogenesis and bone destruction. Oral Dis. 2020;26:983–997. doi:10.1111/odi.13317
  • Lemanska-Perek A, Krzyzanowska-Golab D, Pupek M, Klimeczek P, Witkiewicz W, Katnik-Prastowska I. Analysis of soluble molecular fibronectin-fibrin complexes and EDA-fibronectin concentration in plasma of patients with atherosclerosis. Inflammation. 2016;39:1059–1068. doi:10.1007/s10753-016-0336-0
  • Matarese G, Isola G, Anastasi GP, et al. Immunohistochemical analysis of TGF-beta1 and VEGF in gingival and periodontal tissues: a role of these biomarkers in the pathogenesis of scleroderma and periodontal disease. Int J Mol Med. 2012;30:502–508. doi:10.3892/ijmm.2012.1024
  • Sapudom J, Rubner S, Martin S, Thoenes S, Anderegg U, Pompe T. The interplay of fibronectin functionalization and TGF-beta1 presence on fibroblast proliferation, differentiation and migration in 3D matrices. Biomater Sci. 2015;3:1291–1301. doi:10.1039/C5BM00140D
  • Isola G, Santonocito S, Distefano A, et al. Impact of periodontitis on gingival crevicular fluid miRNAs profiles associated with cardiovascular disease risk. J Periodontal Res. 2023;58:165–174. doi:10.1111/jre.13078
  • Isola G, Polizzi A, Iorio-Siciliano V, Alibrandi A, Ramaglia L, Leonardi R. Effectiveness of a nutraceutical agent in the non-surgical periodontal therapy: a randomized, controlled clinical trial. Clin Oral Investig. 2021;25:1035–1045. doi:10.1007/s00784-020-03397-z
  • Chen SS, Wang K, Zhao J, Wu WC, Wu YF, Zhao L. Increased expression of triggering receptor expressed on myeloid cells 1 and 2 in inflamed human gingiva. J Periodontal Res. 2017;52:512–521. doi:10.1111/jre.12417
  • Lv WQ, Wang HC, Peng J, Wang YX, Jiang JH, Li CY. Gene editing of the extra domain A positive fibronectin in various tumors, amplified the effects of CRISPR/Cas system on the inhibition of tumor progression. Oncotarget. 2017;8:105020–105036. doi:10.18632/oncotarget.21136
  • Zhang L, Chan C. Isolation and enrichment of rat mesenchymal stem cells (MSCs) and separation of single-colony derived MSCs. J Vis Exp. 2010. doi:10.3791/1852-v
  • Sima C, Aboodi GM, Lakschevitz FS, Sun C, Goldberg MB, Glogauer M. Nuclear factor erythroid 2-related factor 2 down-regulation in oral neutrophils is associated with periodontal oxidative damage and severe chronic periodontitis. Am J Pathol. 2016;186:1417–1426. doi:10.1016/j.ajpath.2016.01.013
  • Akiyama K, Aung KT, Talamini L, Huck O, Kuboki T, Muller S. Therapeutic effects of peptide P140 in a mouse periodontitis model. Cell Mol Life Sci. 2022;79(10):518. doi:10.1007/s00018-022-04537-2
  • Kawagishi-Hotta M, Hasegawa S, Igarashi T, et al. Enhancement of individual differences in proliferation and differentiation potentials of aged human adipose-derived stem cells. Regen Ther. 2017;6:29–40. doi:10.1016/j.reth.2016.12.004
  • Henriques A, Silva I, Ines L, et al. CD38, CD81 and BAFFR combined expression by transitional B cells distinguishes active from inactive systemic lupus erythematosus. Clin Exp Med. 2016;16(2):227–232. doi:10.1007/s10238-015-0348-3
  • Thorbert-Mros S, Larsson L, Berglundh T. Cellular composition of long-standing gingivitis and periodontitis lesions. J Periodontal Res. 2015;50(4):535–543. doi:10.1111/jre.12236
  • Takamori Y, Atsuta I, Nakamura H, Sawase T, Koyano K, Hara Y. Histopathological comparison of the onset of peri-implantitis and periodontitis in rats. Clin Oral Implants Res. 2017;28(2):163–170. doi:10.1111/clr.12777
  • de Moraes M, de Lucena HF, de Azevedo PR, Queiroz LM, Costa Ade L. Comparative immunohistochemical expression of RANK, RANKL and OPG in radicular and dentigerous cysts. Arch Oral Biol. 2011;56:1256–1263. doi:10.1016/j.archoralbio.2011.05.009
  • Wang HC, Yang Y, Xu SY, Peng J, Jiang JH, Li CY. The CRISPR/Cas system inhibited the pro-oncogenic effects of alternatively spliced fibronectin extra domain A via editing the genome in salivary adenoid cystic carcinoma cells. Oral Dis. 2015;21:608–618.
  • Traxler EA, Yao Y, Wang YD, et al. A genome-editing strategy to treat beta-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition. Nat Med. 2016;22:987–990. doi:10.1038/nm.4170
  • Liang Y, Wen L, Shang F, Wu J, Sui K, Ding Y. Endothelial progenitors enhanced the osteogenic capacities of mesenchymal stem cells in vitro and in a rat alveolar bone defect model. Arch Oral Biol. 2016;68:123–130. doi:10.1016/j.archoralbio.2016.04.007
  • Hu LY, Zhou Y, Cui WQ, et al. Triggering receptor expressed on myeloid cells 2 (TREM2) dependent microglial activation promotes cisplatin-induced peripheral neuropathy in mice. Brain Behav Immun. 2018;68:132–145. doi:10.1016/j.bbi.2017.10.011
  • Liu H, Dolkas J, Hoang K, et al. The alternatively spliced fibronectin CS1 isoform regulates IL-17A levels and mechanical allodynia after peripheral nerve injury. J Neuroinflammation. 2015;12(1):158. doi:10.1186/s12974-015-0377-6
  • White ES, Sagana RL, Booth AJ, et al. Control of fibroblast fibronectin expression and alternative splicing via the PI3K/Akt/mTOR pathway. Exp Cell Res. 2010;316(16):2644–2653. doi:10.1016/j.yexcr.2010.06.028
  • Shinde AV, Kelsh R, Peters JH, Sekiguchi K, Van De Water L, McKeown-Longo PJ. The alpha4beta1 integrin and the EDA domain of fibronectin regulate a profibrotic phenotype in dermal fibroblasts. Matrix Biol. 2015;41:26–35. doi:10.1016/j.matbio.2014.11.004
  • Kumra H, Reinhardt DP. Fibronectin-targeted drug delivery in cancer. Adv Drug Deliv Rev. 2016;97:101–110.
  • Zheng R, Varney SD, Wu L, DiPersio CM, Van De Water L. Integrin alpha4beta1 is required for IL-1alpha- and Nrf2-dependent, Cox-2 induction in fibroblasts, supporting a mechanism that suppresses alpha-SMA expression. Wound Repair Regen. 2021;29:597–601. doi:10.1111/wrr.12938
  • Jeong BY, Cho KH, Jeong KJ, et al. Rab25 augments cancer cell invasiveness through a beta1 integrin/EGFR/VEGF-A/Snail signaling axis and expression of fascin. Exp Mol Med. 2018;50:e435. doi:10.1038/emm.2017.248
  • Philippeos C, Telerman SB, Oules B, et al. Spatial and single-cell transcriptional profiling identifies functionally distinct human dermal fibroblast subpopulations. J Invest Dermatol. 2018;138:811–825. doi:10.1016/j.jid.2018.01.016
  • Cyranoski D. CRISPR gene-editing tested in a person for the first time. Nature. 2016;539(7630):479. doi:10.1038/nature.2016.20988