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ORIGINAL RESEARCH

Development and Validation of a Rapid and Efficient Prognostic Scoring System for Sepsis Based on Oxygenation Index, Lactate and Glasgow Coma Scale

, , & ORCID Icon
Pages 2955-2966 | Received 13 May 2023, Accepted 10 Jul 2023, Published online: 18 Jul 2023

References

  • Singer M, Deutschman CS, Seymour CW, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315(8):801–810. doi:10.1001/jama.2016.0287
  • Seymour CW, Liu VX, Iwashyna TJ, et al. Assessment of clinical criteria for sepsis: for the third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315(8):762–774. doi:10.1001/jama.2016.0288
  • Fleischmann-Struzek C, Mellhammar L, Rose N, et al. Incidence and mortality of hospital- and ICU-treated sepsis: results from an updated and expanded systematic review and meta-analysis. Intensive Care Med. 2020;46(8):1552–1562. doi:10.1007/s00134-020-06151-x
  • Martin GS, Mannino DM, Moss M. The effect of age on the development and outcome of adult sepsis. Crit Care Med. 2006;34(1):15–21. doi:10.1097/01.CCM.0000194535.82812.BA
  • Partridge L, Deelen J, Slagboom PE. Facing up to the global challenges of ageing. Nature. 2018;561(7721):45–56. doi:10.1038/s41586-018-0457-8
  • Evans L, Rhodes A, Alhazzani W, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med. 2021;47(11):1181–1247.
  • Sivayoham N, Blake LA, Tharimoopantavida SE, Chughtai S, Hussain AN, Rhodes A. Treatment variables associated with outcome in emergency department patients with suspected sepsis. Ann Intensive Care. 2020;10(1):136.
  • Loritz M, Busch HJ, Helbing T, Fink K. Prospective evaluation of the quickSOFA score as a screening for sepsis in the emergency department. Intern Emerg Med. 2020;15(4):685–693.
  • Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med. 1985;13(10):818–829.
  • Vincent JL, Moreno R, Takala J, et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med. 1996;22(7):707–710. doi:10.1007/BF01709751
  • Shapiro NI, Wolfe RE, Moore RB, Smith E, Burdick E, Bates DW. Mortality in Emergency Department Sepsis (MEDS) score: a prospectively derived and validated clinical prediction rule. Crit Care Med. 2003;31(3):670–675. doi:10.1097/01.CCM.0000054867.01688.D1
  • Subbe CP, Kruger M, Rutherford P, Gemmel L. Validation of a modified Early Warning Score in medical admissions. QJM. 2001;94(10):521–526. doi:10.1093/qjmed/94.10.521
  • Brunetti E, Isaia G, Rinaldi G, et al. Comparison of diagnostic accuracies of qSOFA, NEWS, and MEWS to identify sepsis in older inpatients with suspected infection. J Am Med Dir Assoc. 2022;23(5):865–871 e862. doi:10.1016/j.jamda.2021.09.005
  • Usman OA, Usman AA, Ward MA. Comparison of SIRS, qSOFA, and NEWS for the early identification of sepsis in the Emergency Department. Am J Emerg Med. 2019;37(8):1490–1497. doi:10.1016/j.ajem.2018.10.058
  • van der Woude SW, van Doormaal FF, Hutten BA, J Nellen F, Holleman F. Classifying sepsis patients in the emergency department using SIRS, qSOFA or MEWS. Neth J Med. 2018;76(4):158–166.
  • Oduncu AF, Kiyan GS, Yalcinli S. Comparison of qSOFA, SIRS, and NEWS scoring systems for diagnosis, mortality, and morbidity of sepsis in emergency department. Am J Emerg Med. 2021;48:54–59. doi:10.1016/j.ajem.2021.04.006
  • Williams JM, Greenslade JH, Chu K, Brown AF, Lipman J. Severity scores in emergency department patients with presumed infection: a prospective validation study. Crit Care Med. 2016;44(3):539–547. doi:10.1097/CCM.0000000000001427
  • Hsieh CC, Yang CY, Lee CH, Chi CH, Lee CC. Validation of MEDS score in predicting short-term mortality of adults with community-onset bacteremia. Am J Emerg Med. 2020;38(2):282–287. doi:10.1016/j.ajem.2019.05.002
  • Zhang G, Zhang K, Zheng X, Cui W, Hong Y, Zhang Z. Performance of the MEDS score in predicting mortality among emergency department patients with a suspected infection: a meta-analysis. Emerg Med J. 2020;37(4):232–239. doi:10.1136/emermed-2019-208901
  • Suetrong B, Walley KR. Lactic acidosis in sepsis: it’s not all anaerobic: implications for diagnosis and management. Chest. 2016;149(1):252–261. doi:10.1378/chest.15-1703
  • Yu B, Chen M, Zhang Y, et al. Diagnostic and prognostic value of interleukin-6 in emergency department sepsis patients. Infect Drug Resist. 2022;15:5557–5566. doi:10.2147/IDR.S384351
  • Xie Y, Zhuang D, Chen H, Zou S, Chen W, Chen Y. 28-day sepsis mortality prediction model from combined serial interleukin-6, lactate, and procalcitonin measurements: a retrospective cohort study. Eur J Clin Microbiol Infect Dis. 2023;42(1):77–85. doi:10.1007/s10096-022-04517-1
  • Cai C, Qiu G, Hong W, Shen Y, Gong X. Clinical effect and safety of continuous renal replacement therapy in the treatment of neonatal sepsis-related acute kidney injury. BMC Nephrol. 2020;21(1):286. doi:10.1186/s12882-020-01945-z
  • Lu HX, Du J, Wen DL, et al. Development and validation of a novel predictive score for sepsis risk among trauma patients. World J Emerg Surg. 2019;14:11. doi:10.1186/s13017-019-0231-8
  • Jiang Z, Bo L, Xu Z, et al. An explainable machine learning algorithm for risk factor analysis of in-hospital mortality in sepsis survivors with ICU readmission. Comput Methods Programs Biomed. 2021;204:106040. doi:10.1016/j.cmpb.2021.106040
  • Lai Q, Wei W, He Y, Cheng T, Han T, Cao Y. A rapid prognostic score based on bedside Arterial Blood Gas Analysis (ABG) established for predicting 60-day adverse outcomes in patients with acute pancreatitis in the emergency department. J Inflamm Res. 2022;15:5337–5346. doi:10.2147/JIR.S381438
  • Bewick V, Cheek L, Ball J. Statistics review 13: receiver operating characteristic curves. Crit Care. 2004;8(6):508–512. doi:10.1186/cc3000
  • Vickers AJ, Van Calster B, Steyerberg EW. Net benefit approaches to the evaluation of prediction models, molecular markers, and diagnostic tests. BMJ. 2016;352:i6. doi:10.1136/bmj.i6
  • Force ADT, Ranieri VM, Rubenfeld GD, et al. Acute respiratory distress syndrome: the Berlin Definition. JAMA. 2012;307(23):2526–2533. doi:10.1001/jama.2012.5669
  • Rhodes A, Evans LE, Alhazzani W, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016. Intensive Care Med. 2017;43(3):304–377. doi:10.1007/s00134-017-4683-6
  • Englert JA, Bobba C, Baron RM. Integrating molecular pathogenesis and clinical translation in sepsis-induced acute respiratory distress syndrome. JCI Insight. 2019;4(2). doi:10.1172/jci.insight.124061
  • Huppert LA, Matthay MA, Ware LB. Pathogenesis of acute respiratory distress syndrome. Semin Respir Crit Care Med. 2019;40(1):31–39. doi:10.1055/s-0039-1683996
  • Lee C, Choi WJ. Overview of COVID-19 inflammatory pathogenesis from the therapeutic perspective. Arch Pharm Res. 2021;44(1):99–116. doi:10.1007/s12272-020-01301-7
  • Kim JS, Lee JY, Yang JW, et al. Immunopathogenesis and treatment of cytokine storm in COVID-19. Theranostics. 2021;11(1):316–329. doi:10.7150/thno.49713
  • Scott HF, Donoghue AJ, Gaieski DF, Marchese RF, Mistry RD. The utility of early lactate testing in undifferentiated pediatric systemic inflammatory response syndrome. Acad Emerg Med. 2012;19(11):1276–1280. doi:10.1111/acem.12014
  • Jansen TC, van Bommel J, Schoonderbeek FJ, et al. Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial. Am J Respir Crit Care Med. 2010;182(6):752–761. doi:10.1164/rccm.200912-1918OC
  • Scott HF, Brou L, Deakyne SJ, Kempe A, Fairclough DL, Bajaj L. Association between early lactate levels and 30-day mortality in clinically suspected sepsis in children. JAMA Pediatr. 2017;171(3):249–255. doi:10.1001/jamapediatrics.2016.3681
  • Singer AJ, Taylor M, Domingo A, et al. Diagnostic characteristics of a clinical screening tool in combination with measuring bedside lactate level in emergency department patients with suspected sepsis. Acad Emerg Med. 2014;21(8):853–857. doi:10.1111/acem.12444
  • Nichol AD, Egi M, Pettila V, et al. Relative hyperlactatemia and hospital mortality in critically ill patients: a retrospective multi-centre study. Crit Care. 2010;14(1):R25. doi:10.1186/cc8888
  • Aduen J, Bernstein WK, Khastgir T, et al. The use and clinical importance of a substrate-specific electrode for rapid determination of blood lactate concentrations. JAMA. 1994;272(21):1678–1685. doi:10.1001/jama.1994.03520210062033
  • Prytherch DR, Smith GB, Schmidt PE, Featherstone PI. ViEWS--Towards a national early warning score for detecting adult inpatient deterioration. Resuscitation. 2010;81(8):932–937. doi:10.1016/j.resuscitation.2010.04.014
  • Wu BU, Johannes RS, Sun X, Tabak Y, Conwell DL, Banks PA. The early prediction of mortality in acute pancreatitis: a large population-based study. Gut. 2008;57(12):1698–1703. doi:10.1136/gut.2008.152702