248
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Identification of Cell-Cell Communications by Single-Cell RNA Sequencing in End Stage Renal Disease Provides New Insights into Immune Cell Heterogeneity

, , , , &
Pages 4977-5000 | Received 28 Jun 2023, Accepted 17 Oct 2023, Published online: 31 Oct 2023

References

  • Kovesdy CP. Epidemiology of chronic kidney disease: an update 2022. Kidney Int. 2022;12(1):7–11. doi:10.1016/j.kisu.2021.11.003.
  • Lameire NH, Levin A, Kellum JA, et al. Harmonizing acute and chronic kidney disease definition and classification: report of a kidney disease: improving Global Outcomes (KDIGO) consensus conference. Kidney Int. 2021;100(3):516–526. doi:10.1016/j.kint.2021.06.028
  • Cobo G, Lindholm B, Stenvinkel P. Chronic inflammation in end-stage renal disease and dialysis. Nephrol Dial Transplant. 2018;33(suppl_3):iii35–iii40. doi:10.1093/ndt/gfy175.
  • Syed-Ahmed M, Narayanan M. Immune dysfunction and risk of infection in chronic kidney disease. Adv Chronic Kidney Dis. 2019;26(1):8–15. doi:10.1053/j.ackd.2019.01.004.
  • Tammaro A, Kers J, Scantlebery AML, Florquin S. Metabolic flexibility and innate immunity in renal ischemia reperfusion injury: the fine balance between adaptive repair and tissue degeneration. Front Immunol. 2020;11:1346. doi:10.3389/fimmu.2020.01346
  • Gong T, Liu L, Jiang W, Zhou R. DAMP-sensing receptors in sterile inflammation and inflammatory diseases. Nat Rev Immunol. 2020;20(2):95–112. doi:10.1038/s41577-019-0215-7.
  • Satija R, Farrell JA, Gennert D, Schier AF, Regev A. Spatial reconstruction of single-cell gene expression data. Nat Biotechnol. 2015;33(5):495–502. doi:10.1038/nbt.3192.
  • Butler A, Hoffman P, Smibert P, Papalexi E, Satija R. Integrating single-cell transcriptomic data across different conditions, technologies, and species. Nat Biotechnol. 2018;36(5):411–420. doi:10.1038/nbt.4096.
  • Hou Y-C, Lu K-C, Kuo K-L. The efficacy of COVID-19 vaccines in chronic kidney disease and kidney transplantation patients: a narrative review. Vaccines. 2021;9(8). doi:10.3390/vaccines9080885
  • Mora JR, von Andrian UH. T-cell homing specificity and plasticity: new concepts and future challenges. Trends Immunol. 2006;27(5):235–243. doi:10.1016/j.it.2006.03.007
  • Uhl LFK, Gérard A. Modes of communication between T cells and relevance for immune responses. Int J Mol Sci. 2020;21(8):2674. doi:10.3390/ijms21082674.
  • Yen CH, Wu IW, Lee CC, et al. The prognostic value of peripheral total and differential leukocyte count in renal progression: a community-based study. PLoS One. 2021;16(10):e0258210. doi:10.1371/journal.pone.0258210
  • Portolés J, Martín L, Broseta JJ, Cases A. Anemia in chronic kidney disease: from pathophysiology and current treatments, to future agents. Front Med. 2021;8:642296. doi:10.3389/fmed.2021.642296
  • DuPage M, Bluestone JA. Harnessing the plasticity of CD4(+) T cells to treat immune-mediated disease. Nat Rev Immunol. 2016;16(3):149–163. doi:10.1038/nri.2015.18.
  • Steiger S, Rossaint J, Zarbock A, Anders HJ. Secondary immunodeficiency related to kidney disease (SIDKD)-definition, unmet need, and mechanisms. J Am Soc Nephrol. 2022;33(2):259–278. doi:10.1681/asn.2021091257.
  • Hato T, Dagher PC. How the innate immune system senses trouble and causes trouble. Clin J Am Soc Nephrol. 2015;10(8):1459–1469. doi:10.2215/cjn.04680514.
  • Fauci AS, Folkers GK. Pandemic preparedness and response: lessons from COVID-19. J Infect Dis. 2023;228(4):422–425. doi:10.1093/infdis/jiad095.
  • Fattizzo B, Rampi N, Barcellini W. Vaccinations in hematological patients in the era of target therapies: lesson learnt from SARS-CoV-2. Blood Rev. 2023;60:101077. doi:10.1016/j.blre.2023.101077
  • Tade G, Hsu HC, Woodiwiss AJ, et al. Uric acid, ferritin, albumin, parathyroid hormone and gamma-glutamyl transferase concentrations are associated with uremic cardiomyopathy characteristics in non-dialysis and dialysis chronic kidney disease patients. Int J Nephrol Renovasc Dis. 2022;15:353–369. doi:10.2147/ijnrd.S389539.
  • McCullough K, Bolisetty S. Ferritins in kidney disease. Semin Nephrol. 2020;40(2):160–172. doi:10.1016/j.semnephrol.2020.01.007.
  • González-Cuadrado C, Caro-Espada PJ, Chivite-Lacaba M, et al. Hemodialysis-associated immune dysregulation in SARS-CoV-2-infected end-stage renal disease patients. Int J Mol Sci. 2023;24(2):1712. doi:10.3390/ijms24021712
  • Yoon JW, Gollapudi S, Pahl MV, Vaziri ND. Naïve and central memory T-cell lymphopenia in end-stage renal disease. Kidney Int. 2006;70(2):371–376. doi:10.1038/sj.ki.5001550.
  • Betjes MG. Uremia-associated ageing of the thymus and adaptive immune responses. Toxins. 2020;12(4):224. doi:10.3390/toxins12040224.
  • Zhu J. T Helper Cell Differentiation, heterogeneity, and plasticity. Cold Spring Harb Perspect Biol. 2018;10(10):a030338. doi:10.1101/cshperspect.a030338.
  • Cerboni S, Gehrmann U, Preite S, Mitra S. Cytokine-regulated Th17 plasticity in human health and diseases. Immunology. 2021;163(1):3–18. doi:10.1111/imm.13280.
  • Saravia J, Chapman NM, Chi H. Helper T cell differentiation. Cell Mol Immunol. 2019;16(7):634–643. doi:10.1038/s41423-019-0220-6.
  • Zhou X, Yao J, Lin J, Liu J, Dong L, Duan M. Th17/regulatory T-cell imbalance and acute kidney injury in patients with sepsis. J Clin Med. 2022;11(14):4027. doi:10.3390/jcm11144027.
  • Luo Y, Guo J, Zhang P, et al. Mesenchymal stem cell protects injured renal tubular epithelial cells by regulating mTOR-mediated Th17/Treg Axis. Front Immunol. 2021;12:684197. doi:10.3389/fimmu.2021.684197.
  • Kang I, Bucala R. The immunobiology of MIF: function, genetics and prospects for precision medicine. Nat Rev Rheumatol. 2019;15(7):427–437. doi:10.1038/s41584-019-0238-2.
  • Bilsborrow JB, Doherty E, Tilstam PV, Bucala R. Macrophage migration inhibitory factor (MIF) as a therapeutic target for rheumatoid arthritis and systemic lupus erythematosus. Expert Opin Ther Targets. 2019;23(9):733–744. doi:10.1080/14728222.2019.1656718.