81
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Higher High-Mobility Group Box-1 Levels are Associated with White Matter Lesions in Ischemic Stroke Patients

, , , , &
Pages 4441-4449 | Received 24 Jul 2023, Accepted 27 Sep 2023, Published online: 09 Oct 2023

References

  • de Leeuw F, de Groot J, Achten E, et al. Prevalence of cerebral white matter lesions in elderly people: a population based magnetic resonance imaging study. The Rotterdam Scan Study. J Neurol Neurosurg Psychiatry. 2001;70(1):9–14. doi:10.1136/jnnp.70.1.9
  • Honda Y, Noguchi A, Maruyama K, et al. Volumetric analyses of cerebral white matter hyperintensity lesions on magnetic resonance imaging in a Japanese population undergoing medical check-up. Geriatr Gerontol Int. 2015;15:43–47. doi:10.1111/ggi.12672
  • Hilal S, Mok V, Youn Y, Wong A, Ikram M, Chen C. Prevalence, risk factors and consequences of cerebral small vessel diseases: data from three Asian countries. J Neurol Neurosurg Psychiatry. 2017;88(8):669–674. doi:10.1136/jnnp-2016-315324
  • Rudilosso S, Rodríguez-Vázquez A, Urra X, Arboix A. The potential impact of neuroimaging and translational research on the clinical management of lacunar stroke. Int J Mol Sci. 2022;23(3):1497. doi:10.3390/ijms23031497
  • Bos D, Wolters F, Darweesh S, et al. Cerebral small vessel disease and the risk of dementia: a systematic review and meta-analysis of population-based evidence. Alzheimers Dement. 2018;14(11):1482–1492. doi:10.1016/j.jalz.2018.04.007
  • Charidimou A, Pasi M, Fiorelli M, et al. Leukoaraiosis, cerebral hemorrhage, and outcome after intravenous thrombolysis for acute ischemic stroke: a meta-analysis (v1). Stroke. 2016;47(9):2364–2372. doi:10.1161/STROKEAHA.116.014096
  • Zhang X, Tang Y, Xie Y, et al. Total magnetic resonance imaging burden of cerebral small-vessel disease is associated with post-stroke depression in patients with acute lacunar stroke. Eur J Neurol. 2017;24(2):374–380. doi:10.1111/ene.13213
  • Henninger N, Lin E, Haussen D, et al. Leukoaraiosis and sex predict the hyperacute ischemic core volume. Stroke. 2013;44(1):61–67. doi:10.1161/STROKEAHA.112.679084
  • Giurgiutiu D, Yoo A, Fitzpatrick K, et al. Severity of leukoaraiosis, leptomeningeal collaterals, and clinical outcomes after intra-arterial therapy in patients with acute ischemic stroke. J Neurointerv Surg. 2015;7(5):326–330. doi:10.1136/neurintsurg-2013-011083
  • Wang H, Bloom O, Zhang M, et al. HMGB-1 as a late mediator of endotoxin lethality in mice. Science. 1999;285(5425):248–251. doi:10.1126/science.285.5425.248
  • Fonken L, Frank M, Kitt M, et al. The Alarmin HMGB1 mediates age-induced neuroinflammatory priming. J Neurosci. 2016;36(30):7946–7956. doi:10.1523/JNEUROSCI.1161-16.2016
  • Lu B, Wang C, Wang M, et al. Molecular mechanism and therapeutic modulation of high mobility group box 1 release and action: an updated review. Expert Rev Clin Immunol. 2014;10(6):713–727. doi:10.1586/1744666X.2014.909730
  • Agnello D, Wang H, Yang H, Tracey K, Ghezzi P. HMGB-1, a DNA-binding protein with cytokine activity, induces brain TNF and IL-6 production, and mediates anorexia and taste aversion. Cytokine. 2002;18(4):231–236. doi:10.1006/cyto.2002.0890
  • Zhang J, Takahashi H, Liu K, et al. Anti-high mobility group box-1 monoclonal antibody protects the blood-brain barrier from ischemia-induced disruption in rats. Stroke. 2011;42(5):1420–1428. doi:10.1161/STROKEAHA.110.598334
  • Tsukagawa T, Katsumata R, Fujita M, et al. Elevated serum high-mobility group box-1 protein level is associated with poor functional outcome in ischemic stroke. J Stroke Cerebrovasc Dis. 2017;26(10):2404–2411. doi:10.1016/j.jstrokecerebrovasdis.2017.05.033
  • Ved R, Manivannan S, Tasker I, Zaben M. High mobility group box protein 1 and white matter injury following traumatic brain injury: perspectives on mechanisms and therapeutic strategies. Neural Regen Res. 2022;17(8):1739–1740. doi:10.4103/1673-5374.332135
  • Stroke--1989. Recommendations on stroke prevention, diagnosis, and therapy. Report of the WHO task force on stroke and other cerebrovascular disorders. Stroke. 1989;20(10):1407–1431. doi:10.1161/01.STR.20.10.1407
  • Sucharew H, Khoury J, Moomaw C, et al. Profiles of the national institutes of health stroke scale items as a predictor of patient outcome. Stroke. 2013;44(8):2182–2187. doi:10.1161/STROKEAHA.113.001255
  • Adams HJ, Bendixen B, Kappelle L, Biller J, Love B, Gordon D. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of org 10172 in acute stroke treatment. Stroke. 1993;24(1):35–41. doi:10.1161/01.STR.24.1.35
  • Wardlaw J, Smith E, Biessels G, et al. STandards for ReportIng Vascular changes on nEuroimaging (STRIVE v1). Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol. 2013;12(2):822–838. doi:10.1016/S1474-4422(13)70124-8
  • Helenius J, Henninger N. Leukoaraiosis burden significantly modulates the association between infarct volume and national institutes of health stroke scale in ischemic stroke. Stroke. 2015;46(7):1857–1863. doi:10.1161/STROKEAHA.115.009258
  • Fazekas F, Niederkorn K, Schmidt R, et al. White matter signal abnormalities in normal individuals: correlation with carotid ultrasonography, cerebral blood flow measurements, and cerebrovascular risk factors. Stroke. 1988;19(10):1285–1288. doi:10.1161/01.STR.19.10.1285
  • Xie Y, Zhuo X, Xing K, et al. Circulating lipocalin-2 as a novel biomarker for early neurological deterioration and unfavorable prognosis after acute ischemic stroke. Brain Behav. 2023;13(5):e2979. doi:10.1002/brb3.2979
  • Patti J, Helenius J, Puri A, Henninger N. White matter hyperintensity-adjusted critical infarct thresholds to predict a favorable 90-day outcome. Stroke. 2016;47(10):2526–2533. doi:10.1161/STROKEAHA.116.013982
  • Sun L, Hui L, Li Y, Chen X, Liu R, Ma J. Pathogenesis and research progress in leukoaraiosis. Front Hum Neurosci. 2022;16:902731. doi:10.3389/fnhum.2022.902731
  • Grau-Olivares M, Arboix A. Mild cognitive impairment in stroke patients with ischemic cerebral small-vessel disease: a forerunner of vascular dementia? Expert Rev Neurother. 2009;9(8):1201–1217. doi:10.1586/ern.09.73
  • Shi G, Ke D, Gong P, et al. Serum YKL-40 levels and white matter hyperintensities in patients with acute ischemic stroke. J Inflamm Res. 2023;16:311–319. doi:10.2147/JIR.S398701
  • Suda S, Kanamaru T, Okubo S, et al. Urinary albumin-to-creatinine ratio is associated with white matter lesions severity in first-ever stroke patients. J Neurol Sci. 2017;373:258–262. doi:10.1016/j.jns.2017.01.011
  • Shan W, Xu L, Qiu Z, et al. Increased high-mobility group box 1 levels are associated with depression after acute ischemic stroke. Neurol Sci. 2022;43(5):3131–3137. doi:10.1007/s10072-021-05571-x
  • Gao Y, Li D, Lin J, et al. Cerebral small vessel disease: pathological mechanisms and potential therapeutic targets. Front Aging Neurosci. 2022;14:961661. doi:10.3389/fnagi.2022.961661
  • Nishibori M, Wang D, Ousaka D, Wake H. High mobility group box-1 and blood-brain barrier disruption. Cells. 2020;9(12):2650. doi:10.3390/cells9122650
  • Zupan M, Šabović M, Zaletel M, Popovič K, Žvan B. The presence of cerebral and/or systemic endothelial dysfunction in patients with leukoaraiosis--a case control pilot study. BMC Neurol. 2015;15:158. doi:10.1186/s12883-015-0416-z
  • Choi J, Jin X, Kim H, Koh S, Cho H, Kim B. High mobility group box 1 as an autocrine chemoattractant for oligodendrocyte lineage cells in white matter stroke. Stroke. 2023;54(2):575–586. doi:10.1161/STROKEAHA.122.041414
  • Tang D, Kang R, Zeh HJ, Lotze MT. High-mobility group box 1, oxidative stress, and disease. Antioxid Redox Signal. 2011;14(7):1315–1335. doi:10.1089/ars.2010.3356
  • Huo X, Su B, Qin G, Zhao L. HMGB1 promotes Ox-LDL-induced endothelial cell damage by inhibiting PI3K/Akt signaling pathway. BMC Cardiovasc Disord. 2022;22(1):555. doi:10.1186/s12872-022-03003-y
  • Fazekas F, Kleinert R, Offenbacher H, et al. Pathologic correlates of incidental MRI white matter signal hyperintensities. Neurology. 1993;43(9):1683–1689. doi:10.1212/WNL.43.9.1683
  • Simpson J, Ince P, Higham C, et al. Microglial activation in white matter lesions and nonlesional white matter of ageing brains. Neuropathol Appl Neurobiol. 2007;33(6):670–683. doi:10.1111/j.1365-2990.2007.00890.x
  • Fernando M, Simpson J, Matthews F, et al.; MRC Cognitive Function and Ageing Neuropathology Study Group. White matter lesions in an unselected cohort of the elderly: molecular pathology suggests origin from chronic hypoperfusion injury. Stroke. 2006;37(6):1391–1398. doi:10.1161/01.STR.0000221308.94473.14
  • Valdés Hernández Mdel C, Morris Z, Dickie D, et al. Close correlation between quantitative and qualitative assessments of white matter lesions. Neuroepidemiology. 2013;40(1):13–22. doi:10.1159/000341859
  • Kim G, Park K, Avery R, et al. Extensive leukoaraiosis is associated with high early risk of recurrence after ischemic stroke. Stroke. 2014;45(2):479–485. doi:10.1161/STROKEAHA.113.003004