111
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Heme-Inducing Endothelial Pyroptosis Plays a Key Role in Radiofrequency Ablation of Hepatic Hemangioma Leading to Systemic Inflammatory Response Syndrome

ORCID Icon, , , ORCID Icon, , & ORCID Icon show all
Pages 371-385 | Received 12 Sep 2023, Accepted 28 Dec 2023, Published online: 17 Jan 2024

References

  • Ayoobi Yazdi N, Mehrabinejad -M-M, Dashti H, et al. Percutaneous Sclerotherapy with Bleomycin and Ethiodized Oil: a Promising Treatment in Symptomatic Giant Liver Hemangioma. Radiology. 2021;301(2):464–471. doi:10.1148/radiol.2021204444
  • Gao J, Fan RF, Yang JY, et al. Radiofrequency ablation for hepatic hemangiomas: a consensus from a Chinese panel of experts. World J Gastroenterol. 2017;23(39):7077–7086. doi:10.3748/wjg.v23.i39.7077
  • Maruyama H, Tobari M, Nagamatsu H, et al. Ablation for Benign Liver Tumors: current Concepts and Limitations. J Clin Transl Hepatol. 2023;11(1):244–252. doi:10.14218/JCTH.2022.00205
  • Maitra S, Som A, Bhattacharjee S. Accuracy of quick Sequential Organ Failure Assessment (qSOFA) score and systemic inflammatory response syndrome (SIRS) criteria for predicting mortality in hospitalized patients with suspected infection: a meta-analysis of observational studies. Clin Microbiol Infect. 2018;24(11):1123–1129. doi:10.1016/j.cmi.2018.03.032
  • Wu S, Gao R, Yin T, et al. Complications of Radiofrequency Ablation for Hepatic Hemangioma: a Multicenter Retrospective Analysis on 291 Cases. Front Oncol. 2021;11:706619. doi:10.3389/fonc.2021.706619
  • Yang M, Yang X, Wang S, et al. HMGB1-induced endothelial cell pyroptosis is involved in systemic inflammatory response syndrome following radiofrequency ablation of hepatic hemangiomas. Am J Transl Res. 2019;11(12):7555–7567.
  • Salgar S, Bolivar BE, Flanagan JM, et al. The NLRP3 inflammasome fires up heme-induced inflammation in hemolytic conditions. Transl Res. 2022. doi:10.1016/j.trsl.2022.08.011
  • Madyaningrana K, Vijayan V, Nikolin C, et al. Alpha1-antitrypsin counteracts heme-induced endothelial cell inflammatory activation, autophagy dysfunction and death. Redox Biol. 2021;46:102060. doi:10.1016/j.redox.2021.102060
  • Ryter SW. Significance of Heme and Heme Degradation in the Pathogenesis of Acute Lung and Inflammatory Disorders. Int J Mol Sci. 2021;22(11):5509. doi:10.3390/ijms22115509
  • Zhang P, Nguyen J, Abdulla F, et al. Soluble MD-2 and Heme in Sickle Cell Disease Plasma Promote Pro-Inflammatory Signaling in Endothelial Cells. Front Immunol. 2021;12:632709. doi:10.3389/fimmu.2021.632709
  • Wu B, Wu Y, Tang W. Heme Catabolic Pathway in Inflammation and Immune Disorders. Front Pharmacol. 2019;10:825. doi:10.3389/fphar.2019.00825
  • Erdei J, Toth A, Balogh E, et al. Induction of NLRP3 Inflammasome Activation by Heme in Human Endothelial Cells. Oxid Med Cell Longev. 2018;2018:4310816. doi:10.1155/2018/4310816
  • James J, Srivastava A, Varghese MV, et al. Heme induces rapid endothelial barrier dysfunction via the MKK3/p38MAPK axis. Blood. 2020;136(6):749–754. doi:10.1182/blood.2019003986
  • Wei X, Xie F, Zhou X, et al. Role of pyroptosis in inflammation and cancer. Cell Mol Immunol. 2022;19(9):971–992. doi:10.1038/s41423-022-00905-x
  • Huang C, Li J, Zhang C. What role does pyroptosis play in cancer? Mol Metab. 2022;65:101587. doi:10.1016/j.molmet.2022.101587
  • Coll RC, Schroder K, Pelegrin P. NLRP3 and pyroptosis blockers for treating inflammatory diseases. Trends Pharmacol Sci. 2022;43(8):653–668. doi:10.1016/j.tips.2022.04.003
  • Wu Y, Pan B, Zhang Z, et al. Caspase-4/11-Mediated Pulmonary Artery Endothelial Cell Pyroptosis Contributes to Pulmonary Arterial Hypertension. Hypertension. 2022;79(3):536–548. doi:10.1161/HYPERTENSIONAHA.121.17868
  • Kerr NA, de Rivero Vaccari JP, Umland O, et al. Human Lung Cell Pyroptosis Following Traumatic Brain Injury. Cells. 2019;8(1):69. doi:10.3390/cells8010069
  • Jia C, Zhang J, Chen H, et al. Endothelial cell pyroptosis plays an important role in Kawasaki disease via HMGB1/RAGE/cathespin B signaling pathway and NLRP3 inflammasome activation. Cell Death Dis. 2019;10(10):778. doi:10.1038/s41419-019-2021-3
  • Wang S, Yang M, Yang X, et al. Endothelial pyroptosis underlies systemic inflammatory response following radiofrequency ablation of hepatic hemangiomas. Scand J Clin Lab Invest. 2019;79(8):619–628. doi:10.1080/00365513.2019.1689428
  • Yang X, Liu J, Yang MM, et al. Heme is involved in the systemic inflammatory response following radiofrequency ablation of hepatic hemangiomas. Eur J Gastroenterol Hepatol. 2020;32(9):1200–1206. doi:10.1097/MEG.0000000000001636
  • Jeong HG, Cha BG, Kang DW, et al. Ceria Nanoparticles Fabricated with 6-Aminohexanoic Acid that Overcome Systemic Inflammatory Response Syndrome. Adv Healthc Mater. 2019;8(9):e1801548. doi:10.1002/adhm.201801548
  • Thomas JJ, Harp KO, Bashi A, et al. MiR-451a and let-7i-5p loaded extracellular vesicles attenuate heme-induced inflammation in hiPSC-derived endothelial cells. Front Immunol. 2022;13:1082414. doi:10.3389/fimmu.2022.1082414
  • Reis J, Gorgulla C, Massari M, et al. Targeting ROS production through inhibition of NADPH oxidases. Nat Chem Biol. 2023;19(12):1540–1550. doi:10.1038/s41589-023-01457-5
  • Cahill LA, Joughin BA, Kwon WY, et al. Multiplexed Plasma Immune Mediator Signatures Can Differentiate Sepsis From NonInfective SIRS: American Surgical Association 2020 Annual Meeting Paper. Ann Surg. 2020;272(4):604–610. doi:10.1097/SLA.0000000000004379
  • Fransvea P, Costa G, Lepre L, et al. Metabolic Syndrome (MetS), Systemic Inflammatory Response Syndrome (SIRS), and Frailty: is There any Room for Good Outcome in the Elderly Undergoing Emergency Surgery? Front Surg. 2022;9:870082. doi:10.3389/fsurg.2022.870082
  • Pradhan P, Vijayan V, Gueler F, et al. Interplay of Heme with Macrophages in Homeostasis and Inflammation. Int J Mol Sci. 2020;21(3):740. doi:10.3390/ijms21030740
  • Santaterra VAG, Fiusa MML, Hounkpe BW, et al. Endothelial Barrier Integrity Is Disrupted In Vitro by Heme and by Serum From Sickle Cell Disease Patients. Front Immunol. 2020;11:535147. doi:10.3389/fimmu.2020.535147
  • Gbotosho OT, Kapetanaki MG, Kato GJ. The Worst Things in Life are Free: the Role of Free Heme in Sickle Cell Disease. Front Immunol. 2020;11:561917. doi:10.3389/fimmu.2020.561917
  • Gonzales J, Holbert K, Czysz K, et al. Hemin-Induced Endothelial Dysfunction and Endothelial to Mesenchymal Transition in the Pathogenesis of Pulmonary Hypertension Due to Chronic Hemolysis. Int J Mol Sci. 2022;23(9):4763. doi:10.3390/ijms23094763
  • Molema G, Zijlstra JG, van Meurs M, et al. Renal microvascular endothelial cell responses in sepsis-induced acute kidney injury. Nat Rev Nephrol. 2022;18(2):95–112. doi:10.1038/s41581-021-00489-1
  • Serna-Rodriguez MF, Bernal-Vega S, de la Barquera JAO, et al. The role of damage associated molecular pattern molecules (DAMPs) and permeability of the blood-brain barrier in depression and neuroinflammation. J Neuroimmunol. 2022;371:577951. doi:10.1016/j.jneuroim.2022.577951
  • Pan Y, Cai W, Huang J, et al. Pyroptosis in development, inflammation and disease. Front Immunol. 2022;13:991044. doi:10.3389/fimmu.2022.991044
  • Song D, Yeh CT, Wang J, et al. Perspectives on the mechanism of pyroptosis after intracerebral hemorrhage. Front Immunol. 2022;13:989503. doi:10.3389/fimmu.2022.989503
  • Habimana O, Modupe Salami O, Peng J, et al. Therapeutic implications of targeting pyroptosis in Cardiac-related etiology of heart failure. Biochem Pharmacol. 2022;204:115235. doi:10.1016/j.bcp.2022.115235
  • Gan C, Cai Q, Tang C, et al. Inflammasomes and Pyroptosis of Liver Cells in Liver Fibrosis. Front Immunol. 2022;13:896473. doi:10.3389/fimmu.2022.896473
  • Wang P, Gong Q, Hu J, et al. Reactive Oxygen Species (ROS)-Responsive Prodrugs, Probes, and Theranostic Prodrugs: applications in the ROS-Related Diseases. J Med Chem. 2021;64(1):298–325. doi:10.1021/acs.jmedchem.0c01704
  • Liu X, Li M, Chen Z, et al. Mitochondrial calpain-1 activates NLRP3 inflammasome by cleaving ATP5A1 and inducing mitochondrial ROS in CVB3-induced myocarditis. Basic Res Cardiol. 2022;117(1):40. doi:10.1007/s00395-022-00948-1
  • Liu M, Lu J, Chen Y, et al. Sodium Sulfite-Induced Mast Cell Pyroptosis and Degranulation. J Agric Food Chem. 2021;69(27):7755–7764.
  • Matuz-Mares D, Vazquez-Meza H, Vilchis-Landeros MM. NOX as a Therapeutic Target in Liver Disease. Antioxidants. 2022;11(10):2038. doi:10.3390/antiox11102038
  • Nabeebaccus AA, Reumiller CM, Shen J, et al. The regulation of cardiac intermediary metabolism by NADPH oxidases. Cardiovasc Res. 2023;118(17):3305–3319. doi:10.1093/cvr/cvac030
  • Vermot A, Petit-Hartlein I, Smith SME, et al. NADPH Oxidases (NOX): an Overview from Discovery, Molecular Mechanisms to Physiology and Pathology. Antioxidants. 2021;10(6):890. doi:10.3390/antiox10060890
  • Tschopp J, Schroder K. NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production? Nat Rev Immunol. 2010;10(3):210–215. doi:10.1038/nri2725