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ORIGINAL RESEARCH

Lactobacillus Plantarum Promotes Wound Healing by Inhibiting the NLRP3 Inflammasome and Pyroptosis Activation in Diabetic Foot Wounds

, ORCID Icon, , , & ORCID Icon
Pages 1707-1720 | Received 29 Nov 2023, Accepted 28 Feb 2024, Published online: 15 Mar 2024

References

  • Schaper NC, van Netten JJ, Apelqvist J, et al. Practical guidelines on the prevention and management of diabetic foot disease (IWGDF 2019 update). Diabetes Metab Res Rev. 2020;36(Suppl S1):e3266. doi:10.1002/dmrr.3266
  • Lim JZ, Ng NS, Thomas C. Prevention and treatment of diabetic foot ulcers. J R Soc Med. 2017;110:104–109.
  • Armstrong DG, Boulton AJM, Bus SA. Diabetic foot ulcers and their recurrence. N Engl J Med. 2017;376(24):2367–2375.
  • Cawich SO, Islam S, Hariharan S, et al. Trends and determinants of costs associated with the inpatient care of diabetic foot ulcers. J Vasc Surg. 2014;60(5):1247–1254.
  • Salazar JJ, Ennis WJ, Koh TJ. Diabetes medications: impact on inflammation and wound healing. J Diabet Complicat. 2016;30:746–752.
  • Shaikh-Kader A, Houreld NN, Rajendran NK, et al. The link between advanced glycation end products and apoptosis in delayed wound healing. Cell Biochem Funct. 2019;37:432–442.
  • Cheng M, Yang Z, Qiao L, et al. AGEs induce endothelial cells senescence and endothelial barrier dysfunction via miR-1-3p/MLCK signaling pathways. Gene. 2023;30(851):147030.
  • Littig JPB, Moellmer R, Estes AM, et al. Increased population of cd40+ fibroblasts is associated with impaired wound healing and chronic inflammation in diabetic foot ulcers. J Clin Med. 2022;11(21):6335.
  • Ding Y, Xiaofeng D, Zhang H, et al. Relevance of NLRP3 inflammasome-related pathways in the pathology of diabetic wound healing and possible therapeutic targets. Oxid Med Cell Longev. 2022;2022:9687925.
  • Huang W, Jiao J, Liu J, et al. MFG-E8 accelerates wound healing in diabetes by regulating ”NLRP3 inflammasome-neutrophil extracellular traps” axis. Cell Death Discov. 2020;6:84.
  • Sun X, Wang X, Zhao Z, et al. Paeoniflorin inhibited nod-like receptor protein-3 inflammasome and NF-κB-mediated inflammatory reactions in diabetic foot ulcer by inhibiting the chemokine receptor CXCR2. Drug Dev Res. 2021;82(3):404–411.
  • Yao F, Jin Z, Zheng Z, et al. HDAC11 promotes both NLRP3/caspase-1/GSDMD and caspase-3/GSDME pathways causing pyroptosis via ERG in vascular endothelial cells. Cell Death Discov. 2022;8(1):112.
  • Dongming L, Cao X, Zhong L, et al. Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing. Cell Rep Med. 2023;4(8):101129.
  • Marjana TC, Jamie LB, Katelyn EO, et al. Skin microbiota and its interplay with wound healing. Am J Clin Dermatol. 2020;21(Suppl 1):36–43.
  • Bharati KP, Kadamb HP, Ryan YH, et al. The gut-skin microbiota axis and its role in diabetic wound healing-a review based on current literature. Int J Mol Sci. 2022;23(4):2375.
  • Seddik HA, Bendali F, Gancel F, et al. Lactobacillus plantarum and its probiotic and food potentialities. Probiotics Antimicrob Proteins. 2017;9(2):111–122.
  • Mohtashami M, Mohamadi M, Mohsen AN, et al. Lactobacillus bulgaricus and lactobacillus plantarum improve diabetic wound healing through modulating inflammatory factors. Biotechnol Appl Biochem. 2021;68(6):1421–1431.
  • Tsai WH, Chou CH, Huang TY, et al. Heat-killed lactobacilli preparations promote healing in the experimental cutaneous wounds. Cells. 2021;10(11):3264.
  • Gan Y, Chen X, Ruokun Y, et al. Antioxidative and anti-inflammatory effects of lactobacillus plantarum zs62 on alcohol-induced subacute hepatic damage. Oxid Med Cell Longev. 2021;2021:7337988.
  • Wu Y, Hu A, Xin S, et al. Lactobacillus plantarum postbiotics trigger AMPK-dependent autophagy to suppress Salmonella intracellular infection and NLRP3 inflammasome activation. J Cell Physiol. 2023;238(6):1336–1353.
  • Yang S, Feng Y, Chen L, et al. Disulfiram accelerates diabetic foot ulcer healing by blocking NET formation via suppressing the NLRP3/Caspase-1/GSDMD pathway. Transl Res. 2023;254:115–127.
  • Accipe L, Abadie A, Neviere R, et al. Antioxidant activities of natural compounds from Caribbean plants to enhance diabetic wound healing. Antioxidants. 2023;12(5):1079.
  • Zhao Y, Wang Q, Yan S, et al. Bletilla striata polysaccharide promotes diabetic wound healing through inhibition of the NLRP3 inflammasome. Front Pharmacol. 2021;12:659215.
  • Li X, Wang T, Tao Y, et al. MF-094, a potent and selective USP30 inhibitor, accelerates diabetic wound healing by inhibiting the NLRP3 inflammasome. Exp Cell Res. 2022;410(2):112967.
  • Kaur Sandhu S, Raut J, Kumar S, et al. Nanocurcumin and viable Lactobacillus plantarum based sponge dressing for skin wound healing. Int J Pharm. 2023;643:123187.
  • Kim JS, Kim J, Lee SM, et al. Development of guar gum-based dual-layer wound dressing containing lactobacillus plantarum: rapid recovery and mechanically flexibility. Int J Biol Macromol. 2022;221:1572–1579.
  • Ong JS, Taylor TD, Yong CC, et al. Lactobacillus plantarum USM8613 aids in wound healing and suppresses staphylococcus aureus infection at wound sites. Probiotics Antimicrob Proteins. 2020;12(1):125–137.
  • Chuang YC, Cheng MC, Lee CC, et al. Effect of ethanol extract from Lactobacillus plantarum TWK10-fermented soymilk on wound healing in streptozotocin-induced diabetic rat. AMB Express. 2019;9(1):163.
  • Panagiotou D, Filidou E, Gaitanidou M, et al. Role of lactiplantibacillus plantarum UBLP-40, Lactobacillus rhamnosus UBLR-58 and bifidobacterium longum UBBL-64 in the wound healing process of the excisional skin. Nutrients. 2023;15(8):1822.
  • Wang L, Zhao Z, Zhao L, et al. Lactobacillus plantarum DP189 reduces α-SYN aggravation in MPTP-induced parkinson’s disease mice via regulating oxidative damage, inflammation, and gut microbiota disorder. J Agric Food Chem. 2022;70(4):1163–1173.
  • Zhang Y, Li Y, Wang X, et al. Lactobacillus Plantarum NC8 and its metabolite acetate alleviate type 1 diabetes via inhibiting NLRP3. Microb Pathog. 2023;182:106237.