41
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

High Monocyte-to-Lymphocyte Ratio is Associated with Obstructive Sleep Apnea Hypopnea Syndrome

ORCID Icon, , ORCID Icon, &
Pages 2137-2145 | Received 20 Dec 2023, Accepted 14 Mar 2024, Published online: 07 Apr 2024

References

  • Patel SR. Obstructive sleep apnea. Ann Internal Med. 2019;171(11):Itc81–itc96. doi:10.7326/AITC201912030
  • Berry RB, Brooks R, Gamaldo C, et al. AASM scoring manual updates for 2017 (version 2.4). J Clin Sleep Med. 2017;13(5):665–666. doi:10.5664/jcsm.6576
  • Grote L. The global burden of sleep apnoea. Lancet Respir Med. 2019;7(8):645–647. doi:10.1016/S2213-2600(19)30226-7
  • Senaratna CV, Perret JL, Lodge CJ, et al. Prevalence of obstructive sleep apnea in the general population: a systematic review. Sleep Med Rev. 2017;34:70–81. doi:10.1016/j.smrv.2016.07.002
  • Lim DC, Pack AI. Obstructive sleep apnea: update and future. Ann Rev Med. 2017;68(1):99–112. doi:10.1146/annurev-med-042915-102623
  • Weaver TE, Laizner AM, Evans LK, et al. An instrument to measure functional status outcomes for disorders of excessive sleepiness. Sleep. 1997;20(10):835–843.
  • Lin YC, Chen TY, Chien WC, et al. Stimulants associated with reduced risk of hospitalization for motor vehicle accident injury in patients with obstructive sleep apnea-a nationwide cohort study. BMC Pulm Med. 2020;20(1):28. doi:10.1186/s12890-019-1041-1
  • Lv R, Liu X, Zhang Y, et al. Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome. Sig Transd Target Ther. 2023;8(1):218. doi:10.1038/s41392-023-01496-3
  • Redline S, Azarbarzin A, Peker Y. Obstructive sleep apnoea heterogeneity and cardiovascular disease. Nat Rev Cardiol. 2023;20(8):560–573. doi:10.1038/s41569-023-00846-6
  • Baillieul S, Dekkers M, Brill AK, et al. Sleep apnoea and ischaemic stroke: current knowledge and future directions. Lancet Neurol. 2022;21(1):78–88. doi:10.1016/S1474-4422(21)00321-5
  • Liguori C, Maestri M, Spanetta M, et al. Sleep-disordered breathing and the risk of Alzheimer’s disease. Sleep Med Rev. 2021;55:101375. doi:10.1016/j.smrv.2020.101375
  • Gottlieb DJ, Punjabi NM. Diagnosis and management of obstructive sleep apnea: a review. JAMA. 2020;323(14):1389–1400. doi:10.1001/jama.2020.3514
  • Justeau G, Bailly S, Gervès-Pinquié C, et al. Cancer risk in patients with sleep apnoea following adherent 5-year CPAP therapy. Europ resp J. 2022;59(4):2101935. doi:10.1183/13993003.01935-2021
  • Eisenberg E, Legro RS, Diamond MP, et al. Sleep habits of women with infertility. J Clin Endocrinol Metab. 2021;106(11):e4414–e4426. doi:10.1210/clinem/dgab474
  • Lurie A. Inflammation, oxidative stress, and procoagulant and thrombotic activity in adults with obstructive sleep apnea. Adv Cardiol. 2011;46:43–66.
  • Kapur VK, Auckley DH, Chowdhuri S, et al. Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: an American academy of sleep medicine clinical practice guideline. J Clin Sleep Med. 2017;13(3):479–504. doi:10.5664/jcsm.6506
  • Orrù G, Storari M, Scano A, Piras V, Taibi R, Viscuso D. Obstructive Sleep Apnea, oxidative stress, inflammation and endothelial dysfunction-An overview of predictive laboratory biomarkers. Eur Rev Med Pharmacol Sci. 2020;24(12):6939–6948. doi:10.26355/eurrev_202006_21685
  • Lin CW, Lin PW, Chiu LW, et al. Inflammatory biomarkers of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in 563 severe OSA patients before and after surgery. J Otolaryngol. 2023;52(1):49. doi:10.1186/s40463-023-00653-6
  • Cheng HR, Song JY, Zhang YN, et al. High monocyte-to-lymphocyte ratio is associated with stroke-associated pneumonia. Front Neurol. 2020;11:575809. doi:10.3389/fneur.2020.575809
  • Hu B, Yang XR, Xu Y, et al. Systemic immune-inflammation index predicts prognosis of patients after curative resection for hepatocellular carcinoma. Clin Cancer Res. 2014;20(23):6212–6222. doi:10.1158/1078-0432.CCR-14-0442
  • Dziedzic EA, Gąsior JS, Tuzimek A, et al. Investigation of the Associations of Novel Inflammatory Biomarkers-Systemic Inflammatory Index (SII) and Systemic Inflammatory Response Index (SIRI)-with the severity of coronary artery disease and acute coronary syndrome occurrence. Int J Mol Sci. 2022;23(17):9553. doi:10.3390/ijms23179553
  • Guven DC, Sahin TK, Erul E, Kilickap S, Gambichler T, Aksoy S. The association between the pan-immune-inflammation value and cancer prognosis: a systematic review and meta-analysis. Cancers. 2022;14(11):2675. doi:10.3390/cancers14112675
  • Oyama J, Nagatomo D, Yoshioka G, et al. The relationship between neutrophil to lymphocyte ratio, endothelial function, and severity in patients with obstructive sleep apnea. J Cardiol. 2016;67(3):295–302. doi:10.1016/j.jjcc.2015.06.005
  • Kim M, Cho SW, Won TB, Rhee CS, Kim JW. Associations between systemic inflammatory markers based on blood cells and polysomnographic factors in obstructive sleep apnea. Clin Exper Otorhinolaryngol. 2023;16(2):159–164. doi:10.21053/ceo.2022.01368
  • Pau MC, Zinellu A, Mangoni AA, et al. Evaluation of Inflammation and Oxidative Stress Markers in Patients with Obstructive Sleep Apnea (OSA). J Clin Med. 2023;12(12):3935. doi:10.3390/jcm12123935
  • Güneş ZY, Günaydın FM. The relationship between the systemic immune-inflammation index and obstructive sleep apnea. Sleep Breath. 2023;28:1–7.
  • Wang JL, Lu XY, Xu XH, et al. Predictive role of monocyte-to-lymphocyte ratio in patients with Klebsiella pneumonia infection: a single-center experience. Medicine. 2019;98(38):e17215.
  • Chen L, Zeng H, Yang J, et al. Survival and prognostic analysis of preoperative inflammatory markers in patients undergoing surgical resection for laryngeal squamous cell carcinoma. BMC Cancer. 2018;18(1):816. doi:10.1186/s12885-018-4730-x
  • Chen X, Wu J, Zhang F, Ying L, Chen Y. Prognostic significance of pre-operative monocyte-to-lymphocyte ratio in lung cancer patients undergoing radical surgery. Lab Med. 2018;49(2):e29–e39. doi:10.1093/labmed/lmx069
  • Díaz-García E, García-Tovar S, Alfaro E, et al. Inflammasome activation: a keystone of proinflammatory response in obstructive sleep apnea. Am J Respir Crit Care Med. 2022;205(11):1337–1348. doi:10.1164/rccm.202106-1445OC
  • Ommen SR, Hodge DO, Rodeheffer RJ, McGregor CG, Thomson SP, Gibbons RJ. Predictive power of the relative lymphocyte concentration in patients with advanced heart failure. Circulation. 1998;97(1):19–22. doi:10.1161/01.CIR.97.1.19
  • Sercelik A, Besnili AF. Increased monocyte to high-density lipoprotein cholesterol ratio is associated with TIMI risk score in patients with ST-segment elevation myocardial infarction. Revista portuguesa de cardiologia. 2018;37(3):217–223. doi:10.1016/j.repc.2017.06.021
  • Alvarez-Martins I, Remédio L, Matias I, Diogo LN, Monteiro EC, Dias S. The impact of chronic intermittent hypoxia on hematopoiesis and the bone marrow microenvironment. Pflugers Archiv. 2016;468(5):919–932. doi:10.1007/s00424-016-1797-6
  • Hernández-Jiménez E, Cubillos-Zapata C, Toledano V, et al. Monocytes inhibit NK activity via TGF-β in patients with obstructive sleep apnoea. Europ Resp J. 2017;49(6):1602456. doi:10.1183/13993003.02456-2016