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RESEARCH LETTER

Glucocorticoids Do Not Affect the Vascular Component of TRP-Mediated Neurogenic Skin Inflammation

ORCID Icon &
Pages 2835-2838 | Received 13 Feb 2024, Accepted 04 Apr 2024, Published online: 08 May 2024

References

  • Buters TP, Hameeteman PW, Jansen IME, et al. Intradermal lipopolysaccharide challenge as an acute in vivo inflammatory model in healthy volunteers. Br J Clin Pharmacol. 2022;88(2):680–690. doi:10.1111/bcp.14999
  • Buters TP, Hameeteman PW, Jansen IME, et al. Clinical, cellular, and molecular effects of corticosteroids on the response to intradermal lipopolysaccharide administration in healthy volunteers. Clin Pharmacol Ther. 2022;111(4):964–971. doi:10.1002/cpt.2516
  • Marek-Jozefowicz L, Nedoszytko B, Grochocka M, et al. Molecular mechanisms of neurogenic inflammation of the skin. Int J Mol Sci. 2023;24(5):5001. doi:10.3390/ijms24055001
  • Boumpas DT, Chrousos GP, Wilder RL, Cupps TR, Balow JE. Glucocorticoid therapy for immune-mediated diseases: basic and clinical correlates. Ann Intern Med. 1993;119(12):1198–1208. doi:10.7326/0003-4819-119-12-199312150-00007
  • Tafler R, Herbert MK, Schmidt RF, Weis KH. Small reduction of capsaicin-induced neurogenic inflammation in human forearm skin by the glucocorticoid prednicarbate. Agents Actions. 1993;38:C31–34 doi:10.1007/BF01991128.
  • Bamps D. Target Engagement Biomarkers to Bridge the Translational Gap Haunting TRP Channels [Dissertation]. Leuven: KU Leuven; 2023.
  • Ahluwalia A. Topical glucocorticoids and the skin-mechanisms of action: an update. Mediators Inflamm. 1998;7(3):183–193. doi:10.1080/09629359891126