Effectiveness of Quadruple Fortified Salt Compared to Double and Single Fortified Salts in Improving Haemoglobin Levels Among Moderately Anemic Women Aged 18–49 Years in Rural Low Resource Setting: Randomized Clinical Trial

References

• McLean E, Cogswell M, Egli I, Wojdyla D, de Benoist B. Worldwide prevalence of anaemia, WHO vitamin and mineral nutrition information system, 1993–2005. Public Health Nutr. 2009;12(4):444–454. doi:10.1017/S1368980008002401
   PubMed Web of Science ®Google Scholar
• Balarajan Y, Ramakrishnan U, Ozaltin E, Shankar AH, Subramanian SV. Anaemia in low-income and middle-income countries. Lancet. 2011;378(9809):2123–2135. doi:10.1016/S0140-6736(10)62304-5
   PubMed Web of Science ®Google Scholar
• Ali SA, Khan U, Feroz A. Prevalence and determinants of anemia among women of reproductive age in developing countries. J Coll Physicians Surg Pak. 2020;30(2):177–186. doi:10.29271/jcpsp.2020.02.177
   PubMed Web of Science ®Google Scholar
• Kinyoki D, Osgood-Zimmerman AE, Bhattacharjee NV, Kassebaum NJ, Hay SI, Hay SI, Local Burden of Disease Anaemia Collaborators. Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018. Nat Med. 2021;27(10):1761–1782. doi:10.1038/s41591-021-01498-0
   PubMed Web of Science ®Google Scholar
• Teshale AB, Tesema GA, Worku MG, Yeshaw Y, Tessema ZT, Spradley FT. Anemia and its associated factors among women of reproductive age in Eastern Africa: a multilevel mixed-effects generalized linear model. PLoS One. 2020;15(9):e0238957. doi:10.1371/journal.pone.0238957
   PubMed Web of Science ®Google Scholar
• Georgieff MK. Iron deficiency in pregnancy. Am J Obstet Gynecol. 2020;(20):30328. doi:10.1016/j.ajog.2020.03.006
   Google Scholar
• Juul SE, Derman RJ, Auerbach M. Perinatal iron deficiency: implications for mothers and infants. Neonatology. 2019;115(3):269–274. doi:10.1159/000495978
   PubMed Web of Science ®Google Scholar
• World Health Organization. Global Anaemia Reduction Efforts Among Women of Reproductive Age: Impact, Achievement of Targets and the Way Forward for Optimizing Efforts. Geneva: World Health Organization; 2020. Licence: CC BY-NC-SA 3.0 IGO.
   Google Scholar
• Chaparro CM, Suchdev PS. Anemia epidemiology, pathophysiology, and etiology in low- and middle-income countries. Ann N Y Acad Sci. 2019;1450(1):15–31. doi:10.1111/nyas.14092
   PubMed Web of Science ®Google Scholar
• Stevens GA, Finucane MM, De-Regil LM, et al.; Nutrition Impact Model Study Group (Anaemia). Global, regional, and national trends in haemoglobin concentration and prevalence of total and severe anaemia in children and pregnant and non-pregnant women for 1995–2011: a systematic analysis of population-representative data. Lancet Glob Health. 2013;1(1):e16–e25. PMID: 25103581; PMCID: PMC4547326.
   PubMed Web of Science ®Google Scholar
• Muthayya S, Rah JH, Sugimoto JD, Roos FF, Kraemer K, Black RE. The global hidden hunger indices and maps: an advocacy tool for action. PLoS One. 2013;8(6):e67860. doi:10.1371/journal.pone.0067860
   PubMed Web of Science ®Google Scholar
• Black RE, Allen LH, Bhutta ZA, et al. Maternal and child undernutrition: global and regional exposures and health consequences. Lancet. 2008;371(9608):243–260. doi:10.1016/S0140-6736(07)61690-0
   PubMed Web of Science ®Google Scholar
• McLean E, De Benoist B, Allen LH. Review of the magnitude of folate and vitamin B12 deficiencies worldwide. Food Nutr Bull. 2008;29(Supplement 1):38–51. doi:10.1177/15648265080292S107
   Google Scholar
• Bhutta ZA. Micronutrient needs of malnourished children. Curr Opin Clin Nutr Metab Care. 2008;11(3):309. doi:10.1097/MCO.0b013e3282fbf5a0
   PubMed Web of Science ®Google Scholar
• Best C, Neufingerl N, Del Rosso JM, Transler C, van den Briel T, Osendarp S. Can multi micronutrient food fortification improve the micronutrient status, growth, health, and cognition of schoolchildren? A systematic review. Nutr Rev. 2011;69(4):186–204. doi:10.1111/j.1753-4887.2011.00378.x
   PubMed Web of Science ®Google Scholar
• Huffman SL, Baker J, Shumann J, Zehner ER. The case for promoting multiple vitamin and mineral supplements for women of reproductive age in developing countries. Food Nutr Bull. 1999;20(4):379–394. doi:10.1177/156482659902000401
   Google Scholar
• Olson R, Gavin-Smith B, Ferraboschi C, Kraemer K. Food fortification: the advantages, disadvantages and lessons from sight and life programs. Nutrients. 2021;13(4):1118. doi:10.3390/nu13041118
   PubMed Web of Science ®Google Scholar
• Andersson M, Thankachan P, Muthayya S, et al. Dual fortification of salt with iodine and iron: a randomized, double-blind, controlled trial of micronized ferric pyrophosphate and encapsulated ferrous fumarate in southern India. Am J Clin Nutr. 2008;88(5):1378–1387. doi:10.3945/ajcn.2008.26149
   PubMed Web of Science ®Google Scholar
• Evjen-Olsen B, Olsen ØE, Kvåle G. Achieving progress in maternal and neonatal health through integrated and comprehensive healthcare services – experiences from a programme in northern Tanzania. Int J Equity Health. 2009;8(8):27. doi:10.1186/1475-9276-8-27
   PubMedGoogle Scholar
• Rekdal OB. Money, milk and sorghum beer: change and continuity among the Iraqw of Tanzania. Africa. 1996;66(3):367–385. doi:10.2307/1160958
   Web of Science ®Google Scholar
• Mduma ER, Gratz J, Patil C, et al. The etiology, risk factors, and interactions of enteric infections and malnutrition and the consequences for Child Health and Development Study (MAL-ED): description of the Tanzanian site. Clin Infect Dis. 2014;59(suppl–4):S325–30. doi:10.1093/cid/ciu439
   PubMedGoogle Scholar
• National Bureau of Statistics (NBS). Micronutrients: results of the 2010 Tanzania demographic and health survey; 2011. Available from: www.nbs.go.tz. Accessed September 5, 2023.
   Google Scholar
• Hariton E, Locascio JJ. Randomised controlled trials - the gold standard for effectiveness research: study design: randomised controlled trials. BJOG. 2018;125(13):1716. PMID: 29916205; PMCID: PMC6235704. doi:10.1111/1471-0528.15199
   PubMed Web of Science ®Google Scholar
• Sandell EB, Kolthoff IM. Micro determination of iodine by a catalytic method. Mikrochim Acta. 1937;1(1):9–25. doi:10.1007/BF01476194
   Google Scholar
• World Health Organization. Serum and red blood cell folate concentrations for assessing folate status in populations. Vitamin and Mineral Nutrition Information System; 2015:1–7.
   Google Scholar
• Ramírez-Luzuriaga MJ, Larson LM, Mannar V, Martorell R. Impact of double-fortified salt with iron and iodine on haemoglobin, anemia, and iron deficiency anemia: a systematic review and meta-analysis. Adv Nutr. 2018;9(3):207–218. doi:10.1093/advances/nmy008
   PubMed Web of Science ®Google Scholar
• World Health Organization. Guideline: Sodium Intake for Adults and Children. Geneva: World Health Organization; 2012. PMID: 23658998.
   Google Scholar
• Orino K, Lehman L, Tsuji Y, et al. Ferritin and the response to oxidative stress. Biochem J. 2001;357(1):241–247. doi:10.1042/bj3570241
   PubMedGoogle Scholar
• Cook JD, Skikne BS, Lynch SR, Reusser ME. Estimates of iron sufficiency in the US population. Blood. 1986;68(3):726–731. doi:10.1182/blood.V68.3.726.726
   PubMed Web of Science ®Google Scholar
• Bothwell TH, Charlton RW. A general approach of the problems of iron deficiency and iron overload in the population at large. Semin Hematol. 1982;19(1):54–67.
   PubMed Web of Science ®Google Scholar
• Gibson RS, MacDonald AC, Smit-Vanderkooy PD. Serum ferritin and dietary iron parameters in a sample of Canadian preschool children. J Can Dietetic Assoc. 1988;49:23–28.
   Google Scholar
• Silla LM, Zelmanowicz A, Mito I, et al. High prevalence of anemia in children and adult women in an urban population in southern Brazil. PLoS One. 2013;8(7):e68805. doi:10.1371/journal.pone.0068805
   PubMed Web of Science ®Google Scholar
• De Benoist B, McLean E, Egli I, Cogswell M. WHO/CDC. Library cataloguing-in-publication data. In: Worldwide Prevalence of Anaemia 1993–2005: WHO Global Database on Anaemia. Geneva: WHO Press, World Health Organization; 2008:40.
   Google Scholar
• Duque X, Martinez H, Vilchis-Gil J, et al. Effect of supplementation with ferrous sulfate or iron bis-glycinate chelate on ferritin concentration in Mexican schoolchildren: a randomized controlled trial. Nutr J. 2014;13(1):71. doi:10.1186/1475-2891-13-71
   PubMedGoogle Scholar
• Leonard AJ, Chalmers KA, Collins CE, et al. The effect of nutrition knowledge and dietary iron intake on iron status in young women. Appetite. 2014;81:225–231. doi:10.1016/j.appet.2014.06.021
   PubMed Web of Science ®Google Scholar
• De-Regil LM, Jefferds ME, Sylvetsky AC, et al. Intermittent iron supplementation for improving nutrition and development in children under 12 years of age. Cochrane Database Syst Rev. 2011;2011(12):CD009085. doi:10.1002/14651858.CD009085.pub2
   PubMedGoogle Scholar
• Gondolf UH, Tetens I, Michaelsen KF, Trolle E. Iron supplementation is positively associated with increased serum ferritin levels in 9-month-old Danish infants. Br J Nutr. 2013;109(1):103–110. PMID: 22443990. doi:10.1017/S000711451200058X
   PubMed Web of Science ®Google Scholar
• Sadighi J, Nedjat S, Rostami R. Systematic review and meta-analysis of the effect of iron-fortified flour and iron status of the populations worldwide. Public Health Nutr. 2019;22(180):3465–3484. doi:10.1017/S1368980019002179
   PubMedGoogle Scholar
• Koury MJ, Ponka P. New insights into erythropoiesiS: the roles of folate, vitamin B12, and iron. Annu Rev Nutr. 2004;24(1):105–131. PMID: 15189115. doi:10.1146/annurev.nutr.24.012003.132306
   PubMedGoogle Scholar
• Haiden N, Klebermass K, Cardona F, et al. A randomized, controlled trial of the effects of adding vitamin B12 and folate to erythropoietin for the treatment of anemia of prematurity. Pediatrics. 2006;118(1):180–188. PMID: 16818564. doi:10.1542/peds.2005-2475
   PubMed Web of Science ®Google Scholar
• Imbard A, Benoist JF, Blom HJ. Neural tube defects, folic acid and methylation. Int J Environ Res Public Health. 2013;10(9):4352–4389. doi:10.3390/ijerph10094352
   PubMed Web of Science ®Google Scholar