Evaluate the Relationship Between Obstructive Sleep Apnea and Metabolic Syndrome in Real-World Data

References

• Kuna ST. Optimizing chronic management of adults with obstructive sleep apnea. Ann Am Thorac Soc. 2020;17(3):280–281. doi:10.1513/AnnalsATS.201912-897ED
   Web of Science ®Google Scholar
• Franklin KA, Lindberg E. Obstructive sleep apnea is a common disorder in the population-a review on the epidemiology of sleep apnea. J Thorac Dis. 2015;7(8):1311–1322. doi:10.3978/j.issn.2072-1439.2015.06.11
   PubMed Web of Science ®Google Scholar
• Lyons MM, Bhatt NY, Pack AI, Magalang UJ. Global burden of sleep-disordered breathing and its implications. Respirology. 2020;25(7):690–702. doi:10.1111/resp.13838
   PubMed Web of Science ®Google Scholar
• Rowley JA, Lareau S, Fahy BF, Garvey C, Sockrider M. What is obstructive sleep apnea in adults? Am J Respir Crit Care Med. 2017;196(1):P1–P2. doi:10.1164/rccm.1961P1
   Google Scholar
• Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med. 1998;15(7):539–553. doi:10.1002/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S
   PubMed Web of Science ®Google Scholar
• Saklayen MG. The global epidemic of the metabolic syndrome. Curr Hypertens Rep. 2018;20(2):12. doi:10.1007/s11906-018-0812-z
   PubMed Web of Science ®Google Scholar
• Ahmed M, Kumari N, Mirgani Z, et al. Metabolic syndrome; definition, pathogenesis, elements, and the effects of medicinal plants on it’s elements. J Diabetes Metab Disord. 2022;21(1):1011–1022. doi:10.1007/s40200-021-00965-2
   Web of Science ®Google Scholar
• Cura-Esquivel I, Perales-Quintana MM, Torres-Gonzalez L, Guzman-Avilan K, Munoz-Espinosa L, Cordero-Perez P. Metabolic, inflammatory and adipokine differences on overweight/obese children with and without metabolic syndrome: a cross-sectional study. PLoS One. 2023;18(3):e0281381. doi:10.1371/journal.pone.0281381
   Web of Science ®Google Scholar
• Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA. 2002;287(3):356–359. doi:10.1001/jama.287.3.356
   PubMed Web of Science ®Google Scholar
• Assallum H, Song TY, Aronow WS, Chandy D. Obstructive sleep apnoea and cardiovascular disease: a literature review. Arch Med Sci. 2021;17(5):1200–1212. doi:10.5114/aoms.2019.88558
   Web of Science ®Google Scholar
• Hou H, Zhao Y, Yu W, et al. Association of obstructive sleep apnea with hypertension: a systematic review and meta-analysis. J Glob Health. 2018;8(1):010405. doi:10.7189/jogh.08.010405
   PubMed Web of Science ®Google Scholar
• Levy P, Kohler M, McNicholas WT, et al. Obstructive sleep apnoea syndrome. Nat Rev Dis Primers. 2015;1:15015. doi:10.1038/nrdp.2015.15
   PubMed Web of Science ®Google Scholar
• Khandelwal D, Dutta D, Chittawar S, Kalra S. Sleep Disorders in Type 2 Diabetes. Indian J Endocrinol Metab. 2017;21(5):758–761. doi:10.4103/ijem.IJEM_156_17
   PubMedGoogle Scholar
• Sultana R, Sissoho F, Kaushik VP, Raji MA. The case for early use of glucagon-like peptide-1 receptor agonists in obstructive sleep apnea patients with comorbid diabetes and metabolic syndrome. Life. 2022;12(8):1222. doi:10.3390/life12081222
   Google Scholar
• Popadic V, Brajkovic M, Klasnja S, et al. Correlation of dyslipidemia and inflammation with obstructive sleep apnea severity. Front Pharmacol. 2022;13:897279. doi:10.3389/fphar.2022.897279
   PubMed Web of Science ®Google Scholar
• Ahluwalia N, Dwyer J, Terry A, Moshfegh A, Johnson C. Update on NHANES dietary data: focus on collection, release, analytical considerations, and uses to inform public policy. Adv Nutr. 2016;7(1):121–134. doi:10.3945/an.115.009258
   PubMed Web of Science ®Google Scholar
• Wen J, Wang C, Giri M, Guo S. Association between serum folate levels and blood eosinophil counts in American adults with asthma: results from NHANES 2011–2018. Front Immunol. 2023;14:1134621. doi:10.3389/fimmu.2023.1134621
   Web of Science ®Google Scholar
• Wang M, Jian Z, Yuan C, Jin X, Li H, Wang K. Coffee consumption and prostate cancer risk: results from National Health and Nutrition Examination Survey 1999–2010 and Mendelian randomization analyses. Nutrients. 2021;13(7):2317.
   Web of Science ®Google Scholar
• Davies NM, Holmes MV, Davey Smith G. Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians. BMJ. 2018;362:k601. doi:10.1136/bmj.k601
   PubMed Web of Science ®Google Scholar
• Pu B, Gu P, Zheng C, Ma L, Zheng X, Zeng Z. Self-reported and genetically predicted effects of coffee intake on rheumatoid arthritis: epidemiological studies and Mendelian randomization analysis. Front Nutr. 2022;9:926190. doi:10.3389/fnut.2022.926190
   Web of Science ®Google Scholar
• Burgess S, Butterworth A, Malarstig A, Thompson SG. Use of Mendelian randomisation to assess potential benefit of clinical intervention. BMJ. 2012;345:e7325.
   Google Scholar
• MacMillan Uribe AL, Leung CW, Crawford SD, Leak TM. Association between birthplace and time in the United States With Diet Quality in US adolescents: findings from the National Health and Nutrition Examination Survey, 2007 to 2018. J Nutr. 2022;152(11):2505–2513. doi:10.1093/jn/nxac117
   Web of Science ®Google Scholar
• Bowden J, Del Greco MF, Minelli C, Davey Smith G, Sheehan NA, Thompson JR. Assessing the suitability of summary data for two-sample Mendelian randomization analyses using MR-Egger regression: the role of the I2 statistic. Int J Epidemiol. 2016;45(6):1961–1974. doi:10.1093/ije/dyw220
   PubMed Web of Science ®Google Scholar
• Lawlor DA, Harbord RM, Sterne JA, Timpson N, Davey Smith G. Mendelian randomization: using genes as instruments for making causal inferences in epidemiology. Stat Med. 2008;27(8):1133–1163. doi:10.1002/sim.3034
   PubMed Web of Science ®Google Scholar
• Verbanck M, Chen CY, Neale B, Do R. Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases. Nat Genet. 2018;50(5):693–698. doi:10.1038/s41588-018-0099-7
   PubMed Web of Science ®Google Scholar
• Bowden J, Davey Smith G, Burgess S. Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression. Int J Epidemiol. 2015;44(2):512–525. doi:10.1093/ije/dyv080
   PubMed Web of Science ®Google Scholar
• Somers VK, White DP, Amin R, et al. Sleep apnea and cardiovascular disease: an American Heart Association/American College Of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council On Cardiovascular Nursing. In collaboration with the National Heart, Lung, and Blood Institute National Center on Sleep Disorders Research (National Institutes of Health). Circulation. 2008;118(10):1080–1111. doi:10.1161/CIRCULATIONAHA.107.189375
   PubMed Web of Science ®Google Scholar
• Shen Z, Hu J, Wu H, et al. Global research trends and foci of artificial intelligence-based tumor pathology: a scientometric study. J Transl Med. 2022;20(1):409. doi:10.1186/s12967-022-03615-0
   Web of Science ®Google Scholar
• Javaheri S, Barbe F, Campos-Rodriguez F, et al. Sleep Apnea: types, Mechanisms, and Clinical Cardiovascular Consequences. J Am Coll Cardiol. 2017;69(7):841–858. doi:10.1016/j.jacc.2016.11.069
   PubMed Web of Science ®Google Scholar
• Javaheri S, Martinez-Garcia MA, Campos-Rodriguez F. CPAP treatment and cardiovascular prevention: we need to change the design and implementation of our trials. Chest. 2019;156(3):431–437. doi:10.1016/j.chest.2019.04.092
   Web of Science ®Google Scholar
• Elmasry A, Lindberg E, Berne C, et al. Sleep-disordered breathing and glucose metabolism in hypertensive men: a population-based study. J Intern Med. 2001;249(2):153–161. doi:10.1046/j.1365-2796.2001.00787.x
   Web of Science ®Google Scholar
• Ryan S. Adipose tissue inflammation by intermittent hypoxia: mechanistic link between obstructive sleep apnoea and metabolic dysfunction. J Physiol. 2017;595(8):2423–2430. doi:10.1113/JP273312
   PubMed Web of Science ®Google Scholar
• Song SO, He K, Narla RR, Kang HG, Ryu HU, Boyko EJ. Metabolic consequences of obstructive sleep apnea especially pertaining to diabetes mellitus and insulin sensitivity. Diabetes Metab J. 2019;43(2):144–155. doi:10.4093/dmj.2018.0256
   PubMed Web of Science ®Google Scholar
• Alberti A, Sarchielli P, Gallinella E, et al. Plasma cytokine levels in patients with obstructive sleep apnea syndrome: a preliminary study. J Sleep Res. 2003;12(4):305–311. doi:10.1111/j.1365-2869.2003.00361.x
   PubMed Web of Science ®Google Scholar
• Wieser V, Moschen AR, Tilg H. Inflammation, cytokines and insulin resistance: a clinical perspective. Arch Immunol Ther Exp. 2013;61(2):119–125. doi:10.1007/s00005-012-0210-1
   PubMed Web of Science ®Google Scholar
• Wei Z, Chen Y, Upender RP. Sleep disturbance and metabolic dysfunction: the roles of adipokines. Int J Mol Sci. 2022;23(3):1706.
   Web of Science ®Google Scholar
• Wrigley P, Khoury J, Eckerle B, et al. Prevalence of positive troponin and echocardiogram findings and association with mortality in acute ischemic stroke. Stroke. 2017;48(5):1226–1232. doi:10.1161/STROKEAHA.116.014561
   Web of Science ®Google Scholar
• Taheri S, Lin L, Austin D, Young T, Mignot E, Froguel P. Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med. 2004;1(3):e62. doi:10.1371/journal.pmed.0010062
   PubMed Web of Science ®Google Scholar
• Drager LF, Lopes HF, Maki-Nunes C, et al. The impact of obstructive sleep apnea on metabolic and inflammatory markers in consecutive patients with metabolic syndrome. PLoS One. 2010;5(8):e12065. doi:10.1371/journal.pone.0012065
   PubMed Web of Science ®Google Scholar
• Roche F, Sforza E, Pichot V, et al. Obstructive sleep apnoea/hypopnea influences high-density lipoprotein cholesterol in the elderly. Sleep Med. 2009;10(8):882–886. doi:10.1016/j.sleep.2008.07.017
   Web of Science ®Google Scholar
• Nadeem R, Singh M, Nida M, et al. Effect of CPAP treatment for obstructive sleep apnea hypopnea syndrome on lipid profile: a meta-regression analysis. J Clin Sleep Med. 2014;10(12):1295–1302. doi:10.5664/jcsm.4282
   Web of Science ®Google Scholar
• Rosenson RS, Brewer HB, Ansell BJ, et al. Dysfunctional HDL and atherosclerotic cardiovascular disease. Nat Rev Cardiol. 2016;13(1):48–60. doi:10.1038/nrcardio.2015.124
   PubMed Web of Science ®Google Scholar
• Hanikoglu F, Huseyinoglu N, Ozben S, Cort A, Ozdem S, Ozben T. Increased plasma soluble tumor necrosis factor receptor-1 and myeloperoxidase activity in patients with obstructive sleep apnea syndrome. Int J Neurosci. 2015;125(9):655–662. doi:10.3109/00207454.2014.960521
   Web of Science ®Google Scholar
• Meszaros M, Bikov A. Obstructive sleep apnoea and lipid metabolism: the summary of evidence and future perspectives in the pathophysiology of OSA-associated dyslipidaemia. Biomedicines. 2022;10(11):2754.
   Web of Science ®Google Scholar
• Barros D, Garcia-Rio F. Obstructive sleep apnea and dyslipidemia: from animal models to clinical evidence. Sleep. 2019;42(3). doi:10.1093/sleep/zsy236
   Web of Science ®Google Scholar
• Salari N, Khazaie H, Abolfathi M, et al. The effect of obstructive sleep apnea on the increased risk of cardiovascular disease: a systematic review and meta-analysis. Neurol Sci. 2022;43(1):219–231. doi:10.1007/s10072-021-05765-3
   Web of Science ®Google Scholar
• Li Y, Leng Y, Tang H, et al. Assessment of the causal effects of obstructive sleep apnea on atrial fibrillation: a Mendelian randomization study. Front Cardiovasc Med. 2022;9:843681. doi:10.3389/fcvm.2022.843681
   Web of Science ®Google Scholar
• Chen L, Sun X, He Y, Lu Y, Zheng L. Obstructive sleep apnea and atrial fibrillation: insights from a bidirectional Mendelian randomization study. BMC Med Genomics. 2022;15(1):28. doi:10.1186/s12920-022-01180-5
   Web of Science ®Google Scholar
• Linz D, Hohl M, Ukena C, et al. Obstructive respiratory events and premature atrial contractions after cardioversion. Eur Respir J. 2015;45(5):1332–1340. doi:10.1183/09031936.00175714
   PubMed Web of Science ®Google Scholar
• Yu L, Li X, Huang B, et al. Atrial fibrillation in acute obstructive sleep apnea: autonomic nervous mechanism and modulation. J Am Heart Assoc. 2017;6(9). doi:10.1161/JAHA.117.006264
   Web of Science ®Google Scholar
• Collen J, Lettieri C, Wickwire E, Holley A. Obstructive sleep apnea and cardiovascular disease, a story of confounders! Sleep Breath. 2020;24(4):1299–1313. doi:10.1007/s11325-019-01945-w
   PubMed Web of Science ®Google Scholar
• Chen L, Zou S, Wang J. Association of Obstructive Sleep Apnea Syndrome (OSA/OSAHS) with coronary atherosclerosis risk: systematic review and meta-analysis. Comput Math Methods Med. 2022;2022:8905736. doi:10.1155/2022/8905736
   Web of Science ®Google Scholar
• Li YE, Ren J. Association between obstructive sleep apnea and cardiovascular diseases. Acta Biochim Biophys Sin. 2022;54(7):882–892. doi:10.3724/abbs.2022084
   Google Scholar
• Li Y, Miao Y, Zhang Q. Causal associations of obstructive sleep apnea with cardiovascular disease: a Mendelian randomization study. Sleep. 2023;46(3). doi:10.1093/sleep/zsac298
   Web of Science ®Google Scholar
• Zhang J, Wang X, Ma Z, et al. Associations of urinary and blood cadmium concentrations with all-cause mortality in US adults with chronic kidney disease: a prospective cohort study. Environ Sci Pollut Res Int. 2023;30(22):61659–61671.
   Web of Science ®Google Scholar
• Larsson SC, Burgess S, Michaelsson K. Association of genetic variants related to serum calcium levels with coronary artery disease and myocardial infarction. JAMA. 2017;318(4):371–380. doi:10.1001/jama.2017.8981
   PubMed Web of Science ®Google Scholar
• Alberti KG, Eckel RH, Grundy SM, et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009;120(16):1640–1645. doi:10.1161/CIRCULATIONAHA.109.192644
   PubMed Web of Science ®Google Scholar