99
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Functional Connectivity Changes in Amygdala Subregions of Obstructive Sleep Apnea Patients After Six Months of Continuous Positive Airway Pressure Treatment

ORCID Icon, , , , , , , , ORCID Icon & show all
Pages 99-109 | Received 01 Nov 2023, Accepted 16 Jan 2024, Published online: 04 Feb 2024

References

  • Gottlieb DJ, Punjabi NM. Diagnosis and Management of Obstructive Sleep Apnea: a Review. JAMA. 2020;323(14):1389. doi:10.1001/jama.2020.3514
  • Wang SH, Keenan BT, Wiemken A, et al. Effect of Weight Loss on Upper Airway Anatomy and the Apnea–Hypopnea Index. The Importance of Tongue Fat. Am J Respir Crit Care Med. 2020;201(6):718–727. doi:10.1164/rccm.201903-0692OC
  • Senaratna CV, Perret JL, Lodge CJ, et al. Prevalence of obstructive sleep apnea in the general population: a systematic review. Sleep Med Rev. 2017;34:70–81. doi:10.1016/j.smrv.2016.07.002
  • Yeghiazarians Y, Jneid H, Tietjens JR, et al. Obstructive Sleep Apnea and Cardiovascular Disease: a Scientific Statement From the American Heart Association. Circulation. 2021;144(3):e56–e67. doi:10.1161/CIR.0000000000000988
  • Lin J, Song H, Liang M, et al. Advances in the study of OSA and diabetic foot. Diabetol Metab Syndr. 2022;14(1):70. doi:10.1186/s13098-022-00842-9
  • Liguori C, Maestri M, Spanetta M, et al. Sleep-disordered breathing and the risk of Alzheimer’s disease. Sleep Med Rev. 2021;55:101375. doi:10.1016/j.smrv.2020.101375
  • Vanek J, Prasko J, Genzor S, et al. Obstructive sleep apnea, depression and cognitive impairment. Sleep Med. 2020;72:50–58. doi:10.1016/j.sleep.2020.03.017
  • Rosenzweig I, Glasser M, Polsek D, Leschziner GD, Williams SCR, Morrell MJ. Sleep apnoea and the brain: a complex relationship. Lancet Respir Med. 2015;3(5):404–414. doi:10.1016/S2213-2600(15)00090-9
  • Goldstein AN, Walker MP. The Role of Sleep in Emotional Brain Function. Annu Rev Clin Psychol. 2014;10(1):679–708. doi:10.1146/annurev-clinpsy-032813-153716
  • Grandner MA. Sleep, Health, and Society. Sleep Med Clin. 2017;12(1):1–22. doi:10.1016/j.jsmc.2016.10.012
  • Janak PH, Tye KM. From circuits to behaviour in the amygdala. Nature. 2015;517(7534):284–292. doi:10.1038/nature14188
  • Tahmasian M, Rosenzweig I, Eickhoff SB, et al. Structural and functional neural adaptations in obstructive sleep apnea: an activation likelihood estimation meta-analysis. Neurosci Biobehav Rev. 2016;65:142–156. doi:10.1016/j.neubiorev.2016.03.026
  • Park B, Palomares JA, Woo MA, et al. Disrupted functional brain network organization in patients with obstructive sleep apnea. Brain Behav. 2016;6(3):e00441. doi:10.1002/brb3.441
  • Park KM, Kim J. Alterations of Limbic Structure Volumes in Patients with Obstructive Sleep Apnea. Can J Neurol Sci. 2022;1–8. doi:10.1017/cjn.2022.303
  • Han HJ, Lee K, Kim HT, Kim H. Distinctive amygdala subregions involved in emotion-modulated Stroop interference. Soc Cogn Affect Neurosci. 2014;9(5):689–698. doi:10.1093/scan/nst021
  • Amunts K, Kedo O, Kindler M, et al. Cytoarchitectonic mapping of the human amygdala, hippocampal region and entorhinal cortex: intersubject variability and probability maps. Anat Embryol. 2005;210(5–6):343–352. doi:10.1007/s00429-005-0025-5
  • Bickart KC, Hollenbeck MC, Barrett LF, Dickerson BC. Intrinsic Amygdala-Cortical Functional Connectivity Predicts Social Network Size in Humans. J Neurosci. 2012;32(42):14729–14741. doi:10.1523/JNEUROSCI.1599-12.2012
  • Jacob Y, Morris LS, Verma G, Rutter SB, Balchandani P, Murrough JW. Altered hippocampus and amygdala subregion connectome hierarchy in major depressive disorder. Transl Psychiatry. 2022;12(1):209. doi:10.1038/s41398-022-01976-0
  • Cao L, Li H, Liu J, et al. Disorganized functional architecture of amygdala subregional networks in obsessive-compulsive disorder. Commun Biol. 2022;5(1):1184. doi:10.1038/s42003-022-04115-z
  • Yu H, Chen L, Li H, et al. Abnormal resting-state functional connectivity of amygdala subregions in patients with obstructive sleep apnea. NDT. 2019;15:977–987. doi:10.2147/NDT.S191441
  • Schwarz EI, Furian M, Schlatzer C, Stradling JR, Kohler M, Bloch KE. Nocturnal cerebral hypoxia in obstructive sleep apnoea: a randomised controlled trial. Eur Respir J. 2018;51(5). doi:10.1183/13993003.00032-2018
  • Wang G, Goebel JR, Li C, Hallman HG, Gilford TM, Li W. Therapeutic effects of CPAP on cognitive impairments associated with OSA. J Neurol. 2020;267(10):2823–2828. doi:10.1007/s00415-019-09381-2
  • Antic NA, Catcheside P, Buchan C, et al. The Effect of CPAP in Normalizing Daytime Sleepiness, Quality of Life, and Neurocognitive Function in Patients with Moderate to Severe OSA. Sleep. 2011;34(1):111–119. doi:10.1093/sleep/34.1.111
  • Labarca G, Saavedra D, Dreyse J, Jorquera J, Barbe F. Efficacy of CPAP for Improvements in Sleepiness, Cognition, Mood, and Quality of Life in Elderly Patients With OSA: systematic Review and Meta-analysis of Randomized Controlled Trials. Chest. 2020;158(2):751–764. doi:10.1016/j.chest.2020.03.049
  • Munoz A, r ML, Barbe F, Pericas J, Agusti AG. Long-term effects of CPAP on daytime functioning in patients with sleep apnoea syndrome. Eur Respir J. 2000;15(4):676–681. doi:10.1034/j.1399-3003.2000.15d09.x
  • Li P, Shu Y, Liu X, et al. The Effects of CPAP Treatment on Resting-State Network Centrality in Obstructive Sleep Apnea Patients. Front Neurol. 2022;13:801121. doi:10.3389/fneur.2022.801121
  • Li H, Li L, Kong L, et al. Frequency‑Specific Regional Homogeneity Alterations and Cognitive Function in Obstructive Sleep Apnea Before and After Short-Term Continuous Positive Airway Pressure Treatment. NSS. 2021;13:2221–2238. doi:10.2147/NSS.S344842
  • Dalmases M, Solé-Padullés C, Torres M, et al. Effect of CPAP on Cognition, Brain Function, and Structure Among Elderly Patients With OSA. Chest. 2015;148(5):1214–1223. doi:10.1378/chest.15-0171
  • Liu X, Wei Z, Chen L, et al. Effects of 3-month CPAP therapy on brain structure in obstructive sleep apnea: a diffusion tensor imaging study. Front Neurol. 2022;13:913193. doi:10.3389/fneur.2022.913193
  • Fox MD, Raichle ME. Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nat Rev Neurosci. 2007;8(9):700–711. doi: 10.1038/nrn2201
  • Kong L, Li H, Shu Y, et al. Aberrant Resting-State Functional Brain Connectivity of Insular Subregions in Obstructive Sleep Apnea. Front Neurosci. 2022;15:765775. doi:10.3389/fnins.2021.765775
  • Kim WS, Shen G, Liu C, et al. Altered amygdala-based functional connectivity in individuals with attenuated psychosis syndrome and first-episode schizophrenia. Sci Rep. 2020;10(1):17711. doi:10.1038/s41598-020-74771-w
  • Malhotra RK, Kirsch DB, Kristo DA, et al. Polysomnography for Obstructive Sleep Apnea Should Include Arousal-Based Scoring: an American Academy of Sleep Medicine Position Statement. J Clin Sleep Med. 2018;14(7):1245–1247. doi:10.5664/jcsm.7234
  • Kapur VK, Auckley DH, Chowdhuri S, et al. Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: an American Academy of Sleep Medicine Clinical Practice Guideline. J Clin Sleep Med. 2017;13(03):479–504. doi:10.5664/jcsm.6506
  • Heimer L, Van Hoesen GW. The limbic lobe and its output channels: implications for emotional functions and adaptive behavior. Neurosci Biobehav Rev. 2006;30(2):126–147. doi:10.1016/j.neubiorev.2005.06.006
  • Gopal A, Clark E, Allgair A, et al. Dorsal/ventral parcellation of the amygdala: relevance to impulsivity and aggression. Psychiatry Res. 2013;211(1):24–30. doi:10.1016/j.pscychresns.2012.10.010
  • Leech R, Braga R, Sharp DJ. Echoes of the brain within the posterior cingulate cortex. J Neurosci. 2012;32(1):215–222. doi:10.1523/JNEUROSCI.3689-11.2012
  • Foster BL, Koslov SR, Aponik-Gremillion L, Monko ME, Hayden BY, Heilbronner SR. A tripartite view of the posterior cingulate cortex. Nat Rev Neurosci. 2023;24(3):173–189. doi:10.1038/s41583-022-00661-x
  • Vanneste S, Luckey A, McLeod SL, Robertson IH, To WT. Impaired posterior cingulate cortex-parahippocampus connectivity is associated with episodic memory retrieval problems in amnestic mild cognitive impairment. Eur J Neurosci. 2021;53(9):3125–3141. doi:10.1111/ejn.15189
  • Filipovic B, Đuric V, Filipovic N, et al. Anatomical Brain Changes and Cognitive Abilities in Patients with Obstructive Sleep Apnea Syndrome and Nonalcoholic Fatty Liver Disease. Can J Gastroenterol Hepatol. 2021;2021:8873652. doi:10.1155/2021/8873652
  • Yaouhi K, Bertran F, Clochon P, et al. A combined neuropsychological and brain imaging study of obstructive sleep apnea. J Sleep Res. 2009;18(1):36–48. doi:10.1111/j.1365-2869.2008.00705.x
  • Li HJ, Nie X, Gong H, Zhang W, Nie S, Peng DC. Abnormal resting-state functional connectivity within the default mode network subregions in male patients with obstructive sleep apnea. NDT. 2016;203. doi:10.2147/NDT.S97449
  • Li H, Li L, Shao Y, et al. Abnormal Intrinsic Functional Hubs in Severe Male Obstructive Sleep Apnea: evidence from a Voxel-Wise Degree Centrality Analysis. PLoS One. 2016;11(10):e0164031. doi:10.1371/journal.pone.0164031
  • Chang YT, Chen YC, Chen YL, et al. Functional connectivity in default mode network correlates with severity of hypoxemia in obstructive sleep apnea. Brain Behav. 2020;10(12):e01889. doi:10.1002/brb3.1889
  • Fernandes M, Mari L, Chiaravalloti A, et al. 18F-FDG PET, cognitive functioning, and CSF biomarkers in patients with obstructive sleep apnoea before and after continuous positive airway pressure treatment. J Neurol. 2022;269(10):5356–5367. doi:10.1007/s00415-022-11182-z
  • Raam T, Hong W. Organization of neural circuits underlying social behavior: a consideration of the medial amygdala. Curr Opin Neurobiol. 2021;68:124–136. doi:10.1016/j.conb.2021.02.008
  • Cross NE, Memarian N, Duffy SL, et al. Structural brain correlates of obstructive sleep apnoea in older adults at risk for dementia. Eur Respir J. 2018;52(1):1800740. doi:10.1183/13993003.00740-2018
  • Zhou L, Shan X, Peng Y, et al. Reduced regional homogeneity and neurocognitive impairment in patients with moderate-to-severe obstructive sleep apnea. Sleep Medicine. 2020;75:418–427. doi:10.1016/j.sleep.2020.09.009
  • Baril AA, Gagnon K, Arbour C, et al. Regional Cerebral Blood Flow during Wakeful Rest in Older Subjects with Mild to Severe Obstructive Sleep Apnea. Sleep. 2015;38(9):1439–1449. doi:10.5665/sleep.4986
  • Ruehland WR, Rochford PD, Pierce RJ, et al. Genioglossus muscle responses to resistive loads in severe OSA patients and healthy control subjects. J Appl Physiol. 2019;127(6):1586–1598. doi:10.1152/japplphysiol.00186.2019
  • Song X, Roy B, Vacas S, et al. Brain Regional Homogeneity Changes After Short-term Positive Airway Pressure Treatment in Patients with Obstructive Sleep Apnea. Sleep Med. 2022;91:12–20. doi:10.1016/j.sleep.2022.02.005
  • Liu X, Chen L, Duan W, et al. Abnormal Functional Connectivity of Hippocampal Subdivisions in Obstructive Sleep Apnea: a Resting-State Functional Magnetic Resonance Imaging Study. Front Neurosci. 2022;16:850940. doi:10.3389/fnins.2022.850940
  • Briggs RG, Lin YH, Dadario NB, et al. Anatomy and White Matter Connections of the Middle Frontal Gyrus. World Neurosurg. 2021;150:e520–e529. doi:10.1016/j.wneu.2021.03.045
  • Xu P, Wang M, Zhang T, Zhang J, Jin Z, Li L. The role of middle frontal gyrus in working memory retrieval by the effect of target detection tasks: a simultaneous EEG-fMRI study. Brain Struct Funct. 2023. doi:10.1007/s00429-023-02687-y
  • Bai J, Wen H, Tai J, et al. Altered Spontaneous Brain Activity Related to Neurologic and Sleep Dysfunction in Children With Obstructive Sleep Apnea Syndrome. Front Neurosci. 2021;15:595412. doi:10.3389/fnins.2021.595412
  • Ju G, Yoon IY, Lee SD, Kim YK, Yoon E, Kim JW. Modest Changes in Cerebral Glucose Metabolism in Patients with Sleep Apnea Syndrome after Continuous Positive Airway Pressure Treatment. Respiration. 2012;84(3):212–218. doi:10.1159/000338117
  • Toth M, Faludi B, Kondakor I. Effects of CPAP-Therapy on Brain Electrical Activity in Obstructive Sleep Apneic Patients: a Combined EEG Study Using LORETA and Omega Complexity: reversible Alterations of Brain Activity in OSAS. Brain Topogr. 2012;25(4):450–460. doi:10.1007/s10548-012-0243-0
  • Marillier M, Gruet M, Baillieul S, et al. Impaired cerebral oxygenation and exercise tolerance in patients with severe obstructive sleep apnea syndrome. Sleep Med. 2018;51:37–46. doi:10.1016/j.sleep.2018.06.013
  • Tonon C, Vetrugno R, Lodi R, et al. Proton magnetic resonance spectroscopy study of brain metabolism in obstructive sleep apnoea syndrome before and after continuous positive airway pressure treatment. Sleep. 2007;30(3):305–311. doi:10.1093/sleep/30.3.305