Advanced search
Publication Cover
Nature and Science of Sleep Volume 16, 2024 - Issue
Submit an article Journal homepage
48
Views
0
CrossRef citations to date
0
Altmetric
Original Research

Characterisation of Symptom and Polysomnographic Profiles Associated with Cardiovascular Risk in a Sleep Clinic Population with Obstructive Sleep Apnoea

Emily Kemp1 Department of Respiratory Medicine, Royal North Shore Hospital, St Leonards, NSW, AustraliaView further author information
,
Kate Sutherland1 Department of Respiratory Medicine, Royal North Shore Hospital, St Leonards, NSW, Australia;2 Charles Perkins Centre, University of Sydney, Camperdown, NSW, Australia;3 Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, AustraliaORCID Iconhttps://orcid.org/0000-0001-6106-7303View further author information
ORCID Icon,
Yu Sun Bin2 Charles Perkins Centre, University of Sydney, Camperdown, NSW, Australia;3 Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, AustraliaORCID Iconhttps://orcid.org/0000-0002-4954-2658View further author information
ORCID Icon,
Andrew SL Chan1 Department of Respiratory Medicine, Royal North Shore Hospital, St Leonards, NSW, Australia;2 Charles Perkins Centre, University of Sydney, Camperdown, NSW, Australia;3 Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, AustraliaORCID Iconhttps://orcid.org/0000-0003-2559-3706View further author information
ORCID Icon,
Hasthi Dissanayake2 Charles Perkins Centre, University of Sydney, Camperdown, NSW, Australia;3 Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, AustraliaView further author information
,
Brendon J Yee2 Charles Perkins Centre, University of Sydney, Camperdown, NSW, Australia;3 Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia;4 Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, NSW, Australia;5 Centre for Integrated Research and Understanding of Sleep (CIRUS), Woolcock Institute of Medical Research, Glebe, NSW, AustraliaView further author information
,
Kristina Kairaitis2 Charles Perkins Centre, University of Sydney, Camperdown, NSW, Australia;3 Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia;6 Ludwig Engel Centre for Respiratory Research, Westmead Institute for Medical Research, Westmead, NSW, Australia;7 Department of Respiratory and Sleep Medicine, Westmead Hospital, Westmead, NSW, AustraliaView further author information
,
John Robert Wheatley2 Charles Perkins Centre, University of Sydney, Camperdown, NSW, Australia;3 Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia;6 Ludwig Engel Centre for Respiratory Research, Westmead Institute for Medical Research, Westmead, NSW, Australia;7 Department of Respiratory and Sleep Medicine, Westmead Hospital, Westmead, NSW, AustraliaView further author information
,
Philip de Chazal2 Charles Perkins Centre, University of Sydney, Camperdown, NSW, Australia;8 School of Biomedical Engineering, The University of Sydney, Darlington, NSW, AustraliaView further author information
,
Amanda J Piper2 Charles Perkins Centre, University of Sydney, Camperdown, NSW, Australia;4 Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, NSW, AustraliaView further author information
&
Peter A Cistulli1 Department of Respiratory Medicine, Royal North Shore Hospital, St Leonards, NSW, Australia;2 Charles Perkins Centre, University of Sydney, Camperdown, NSW, Australia;3 Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, AustraliaCorrespondence[email protected]
View further author information
 show all
Pages 461-471 | Received 31 Dec 2023, Accepted 27 Apr 2024, Published online: 05 May 2024

References

  • Benjafield A, Ayas NT, Eastwood PR, et al. Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis. Lancet Respir Med. 2019;7(8):687–698. doi:10.1016/S2213-2600(19)30198-5
  • Bauters F, Rietzschel ER, Hertegonne KB, Chirinos JA. The link between obstructive sleep apnea and cardiovascular disease. Curr Atheroscler Rep. 2016;18(1):1. doi:10.1007/s11883-015-0556-z
  • Bonsignore MR, Suarez Giron MC, Marrone O, Castrogiovanni A, Montserrat JM. Personalised medicine in sleep respiratory disorders: focus on obstructive sleep apnoea diagnosis and treatment. Eur Respir Rev. 2017;26(146). doi:10.1183/16000617.0069-2017
  • Zinchuk A, Yaggi HK. Phenotypic Subtypes of OSA: a challenge and opportunity for precision medicine. Chest. 2020;157(2):403–420. doi:10.1016/j.chest.2019.09.002
  • Zinchuk A, Gentry MJ, Concato J, Yaggi HK. Phenotypes in obstructive sleep apnea: a definition, examples and evolution of approaches. Sleep Med Rev. 2017;35:113–123. doi:10.1016/j.smrv.2016.10.002
  • Sutherland K, Yee BJ, Kairaitis K, Wheatley J, de Chazal P, Cistulli PA. A phenotypic approach for personalised management of obstructive sleep apnoea. Curr Otorhinolaryngol Rep. 2021;1–15:2167.
  • Mazzotti DR, Keenan BT, Lim DC, Gottlieb DJ, Kim J, Pack AI. Symptom subtypes of obstructive sleep apnea predict incidence of cardiovascular outcomes. Am J Respir Crit Care Med. 2019;200(4):493–506. doi:10.1164/rccm.201808-1509OC
  • Zinchuk A, Jeon S, Koo BB, et al. Polysomnographic phenotypes and their cardiovascular implications in obstructive sleep apnoea. Thorax. 2018;73(5):472–480. doi:10.1136/thoraxjnl-2017-210431
  • Azarbarzin A, Sands SA, Stone KL, et al. The hypoxic burden of sleep apnoea predicts cardiovascular disease-related mortality: the osteoporotic fractures in men study and the sleep heart health study. Eur Heart J. 2018;3:1.
  • Aurora RN, Crainiceanu C, Gottlieb DJ, Kim JS, Punjabi NM. Obstructive sleep apnea during REM sleep and cardiovascular disease. Am J Respir Crit Care Med. 2018;197(5):653–660. doi:10.1164/rccm.201706-1112OC
  • D’Agostino RB, Vasan RS, Pencina MJ, et al. General cardiovascular risk profile for use in primary care: the Framingham heart study. Circulation. 2008;117(6):743–753. doi:10.1161/CIRCULATIONAHA.107.699579
  • Sutherland K, Sarkissian N, Amis TC, et al. Sydney Sleep Biobank (SSB): development of a research resource. In Journal of Sleep Research. 2019;28:3.
  • Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep. 1991;14(6):540–545. doi:10.1093/sleep/14.6.540
  • Chasens ER, Ratcliffe SJ, Weaver TE. Development of the FOSQ-10: a short version of the functional outcomes of sleep questionnaire. Sleep. 2009;32(7):915–919. doi:10.1093/sleep/32.7.915
  • Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh sleep quality index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989;28(2):193–213. doi:10.1016/0165-1781(89)90047-4
  • Magalang UJ, Chen NH, Cistulli PA, et al. Agreement in the scoring of respiratory events and sleep among international sleep centers. Sleep. 2013;36(4):591–596. doi:10.5665/sleep.2552
  • Bastien CH, Vallieres A, Morin CM. Validation of the insomnia severity index as an outcome measure for insomnia research. Sleep Med. 2001;2(4):297–307. doi:10.1016/S1389-9457(00)00065-4
  • Netzer NC, Stoohs RA, Netzer CM, Clark K, Strohl KP. Using the berlin questionnaire to identify patients at risk for the sleep apnea syndrome. Ann Intern Med. 1999;131(7):485. doi:10.7326/0003-4819-131-7-199910050-00002
  • Keenan BT, Kim J, Singh B, et al. Recognizable clinical subtypes of obstructive sleep apnea across international sleep centers: a cluster analysis. Sleep. 2018;41(3). doi:10.1093/sleep/zsx214
  • Ye L, Pien GW, Ratcliffe SJ, et al. The different clinical faces of obstructive sleep apnoea: a cluster analysis. Eur Respir J. 2014;44(6):1600–1607. doi:10.1183/09031936.00032314
  • Berry R, Quan S, Abreu A, et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications. Vol. 2. Darien, Illinois: American Academy of Sleep Medicine; 2020.
  • Jorgensen G, Downey C, Goldin J, Melehan K, Rochford P, Ruehland W. An Australasian commentary on the AASM manual for the scoring of sleep and associated events. Sleep Biol Rhythms. 2020;18(3):163–185. doi:10.1007/s41105-020-00259-9
  • Jamovi. The Jamovi Project; 2022. Available from: https://www.jamovi.org. Accessed May 1, 2024.
  • Sofi F, Cesari F, Casini A, Macchi C, Abbate R, Gensini GF. Insomnia and risk of cardiovascular disease: a meta-analysis. Eur J Prev Cardiol. 2014;21(1):57–64. doi:10.1177/2047487312460020
  • Bertisch SM, Pollock BD, Mittleman MA, et al. Insomnia with objective short sleep duration and risk of incident cardiovascular disease and all-cause mortality. Sleep Heart Health Study Sleep. 2018;41:6.
  • Lechat B, Appleton S, Melaku YA, et al. The association of co‐morbid insomnia and sleep apnea with prevalent cardiovascular disease and incident cardiovascular events. J Sleep Res. 2022;31(5). doi:10.1111/jsr.13563
  • Empana JP, Dauvilliers Y, Dartigues JF, et al. Excessive daytime sleepiness is an independent risk indicator for cardiovascular mortality in community-dwelling elderly: the three city study. Stroke. 2009;40(4):1219–1224. doi:10.1161/STROKEAHA.108.530824
  • Gooneratne NS, Richards KC, Joffe M, et al. Sleep disordered breathing with excessive daytime sleepiness is a risk factor for mortality in older adults. Sleep. 2011;34(4):435–442. doi:10.1093/sleep/34.4.435
  • Kim J, Keenan BT, Lim DC, Lee SK, Pack AI, Shin C. Symptom-based subgroups of Koreans with obstructive sleep apnea. J Clin Sleep Med. 2018;14(3):437–443. doi:10.5664/jcsm.6994
  • González KA, Tarraf W, Wallace DM, et al. Phenotypes of obstructive sleep apnea in the Hispanic Community Health Study/Study of Latinos. Sleep. 2021;44(12). doi:10.1093/sleep/zsab181
  • Labarca G, Dreyse J, Salas C, Letelier F, Jorquera J. A validation study of four different cluster analyses of OSA and the incidence of cardiovascular mortality in a Hispanic population. Chest. 2021;160(6):2266–2274. doi:10.1016/j.chest.2021.06.047
  • Trzepizur W, Blanchard M, Ganem T, et al. Sleep apnea–specific hypoxic burden, symptom subtypes, and risk of cardiovascular events and all-cause mortality. Am J Respir Crit Care Med. 2022;205(1):108–117. doi:10.1164/rccm.202105-1274OC
  • Thorarinsdottir EH, Gislason T, Pack AI, et al. Evaluation of excessive daytime sleepiness in obstructive sleep apnea across international sleep centers. Sleep. 2023;46(8). doi:10.1093/sleep/zsac271
  • Archontogeorgis K, Voulgaris A, Nena E, et al. Cardiovascular risk assessment in a cohort of newly diagnosed patients with obstructive sleep apnea syndrome. Cardiol Res Pract. 2018;2018:6572785. doi:10.1155/2018/6572785
  • Wang XF, Li QY, Wan HY, Li M. The influencing factors of Framingham cardiovascular risk score in patients with obstructive sleep apnea-hypopnea syndrome. Zhonghua Yi Xue Za Zhi. 2007;87(31):2176–2180.
  • Cintra F, Bittencourt LR, Santos-Silva R, et al. The association between the Framingham risk score and sleep: a Sao Paulo epidemiological sleep study. Sleep Med. 2012;13(6):577–582. doi:10.1016/j.sleep.2011.12.016
  • Carratù P, Di Ciaula A, Dragonieri S, et al. Relationships between obstructive sleep apnea syndrome and cardiovascular risk in a naïve population of southern Italy. Int J Clin Pract. 2021;75(12). doi:10.1111/ijcp.14952
  • Punjabi NM, Caffo BS, Goodwin JL, et al. Sleep-disordered breathing and mortality: a prospective cohort study. PLoS Med. 2009;6(8):e1000132. doi:10.1371/journal.pmed.1000132
  • Stone KL, Blackwell TL, Ancoli-Israel S, et al. Sleep disordered breathing and risk of stroke in older community-dwelling men. Sleep. 2016;39(3):531–540. doi:10.5665/sleep.5520
  • Azarbarzin A, Sands SA, Taranto-Montemurro L, Redline S, Wellman A. Hypoxic burden captures sleep apnoea-specific nocturnal hypoxaemia. Eur Heart J. 2019;40(35):2989–2990. doi:10.1093/eurheartj/ehz274
  • Azarbarzin A, Sands SA, Taranto-Montemurro L, et al. The sleep apnea-specific hypoxic burden predicts incident heart failure. Chest. 2020;158(2):739–750. doi:10.1016/j.chest.2020.03.053
  • Labarca G, Jorquera J, Dreyse J, Salas C, Letelier F. Hypoxemic features of obstructive sleep apnea and the risk of mortality: a cluster analysis. Sleep Breathing. 2021;25(1):95–103. doi:10.1007/s11325-020-02064-7
  • Kim JW, Won TB, Rhee CS, Park YM, Yoon IY, Cho SW. Polysomnographic phenotyping of obstructive sleep apnea and its implications in mortality in Korea. Sci Rep. 2020;10(1):13207. doi:10.1038/s41598-020-70039-5
  • Ren R, Zhang Y, Yang L, Somers VK, Covassin N, Tang X. Association between arousals during sleep and hypertension among patients with obstructive sleep apnea. J Am Heart Assoc. 2022;11(1). doi:10.1161/JAHA.121.022141

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.