References
- Kanasaki K , KalluriR. The biology of preeclampsia. Kidney Int.76(8), 831–837 (2009).
- Noris M , PericoN, RemuzziG. Mechanisms of disease: pre-eclampsia. Nat. Clin. Pract. Nephrol.1(2), 98–114 (2005).
- Raijmakers MT , DechendR, PostonL. Oxidative stress and preeclampsia: rationale for antioxidant clinical trials. Hypertension44(4), 374–380 (2004).
- Dimitriadis E , RolnikDL, ZhouWet al. Pre-eclampsia. Nat. Rev. Dis. Primers9(1), 8 (2023).
- Schoots MH , GordijnSJ, ScherjonSA, Van GoorH, HillebrandsJ-L. Oxidative stress in placental pathology. Placenta69, 153–161 (2018).
- Pennington KA , SchlittJM, JacksonDL, SchulzLC, SchustDJ. Preeclampsia: multiple approaches for a multifactorial disease. Dis. Model. Mech.5(1), 9–18 (2012).
- Ryter SW , AlamJ, ChoiAM. Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications. Physiol. Rev.86(2), 583–650 (2006).
- Dunn LL , MidwinterRG, NiJ, HamidHA, ParishCR, StockerR. New insights into intracellular locations and functions of heme oxygenase-1. Antioxid. Redox. Signal.20(11), 1723–1742 (2014).
- Dulak J , DeshaneJ, JozkowiczA, AgarwalA. Heme oxygenase-1 and carbon monoxide in vascular pathobiology: focus on angiogenesis. Circulation117(2), 231–241 (2008).
- Gallardo V , GonzálezM, ToledoF, SobreviaL. Role of heme oxygenase 1 and human chorionic gonadotropin in pregnancy associated diseases. Biochim. Biophys. Acta Mol. Basis Dis.1866(2), 165522 (2020).
- Ramma W , AhmedA. Therapeutic potential of statins and the induction of heme oxygenase-1 in preeclampsia. J. Reprod. Immunol.101, 153–160 (2014).
- George EM , CockrellK, AranayM, CsongradiE, StecDE, GrangerJP. Induction of heme oxygenase 1 attenuates placental ischemia–induced hypertension. Hypertension57(5), 941–948 (2011).
- Chigusa Y , TatsumiK, KondohEet al. Decreased lectin-like oxidized LDL receptor 1 (LOX-1) and low Nrf2 activation in placenta are involved in preeclampsia. J. Clin. Endocrinol. Metab.97(10), e1862–e1870 (2012).
- Maebayashi A , YamamotoT, AzumaHet al. Expression of placenta growth factor, soluble fms-like tyrosine kinase-1, metal-responsive transcription factor-1, heme oxygenase 1 and hypoxia inducible factor-1α mRNAs in pre-eclampsia placenta and the effect of pre-eclampsia sera on their expression of choriocarcinoma cells. J. Obstet. Gynaecol.40(10), 2095–2103 (2014).
- Ahmed A , RahmanM, ZhangXet al. Induction of placental heme oxygenase-1 is protective against TNFα-induced cytotoxicity and promotes vessel relaxation. Mol. Med.6(5), 391–409 (2000).
- Farina A , SekizawaA, DeSanctis Pet al. Gene expression in chorionic villous samples at 11 weeks’ gestation from women destined to develop preeclampsia. Prenat. Diagn.28(10), 956–961 (2008).
- Shi J , SuM. HMOX1 participates in pre-eclampsia by regulating the proliferation, apoptosis, and angiogenesis modulation potential of mesenchymal stem cells via VEGF. Biochem. Genet. ( In press). 10.1007/s10528-023-10474-x
- Feng H , WangL, ZhangG, ZhangZ, GuoW. Oxidative stress activated by Keap-1/Nrf2 signaling pathway in pathogenesis of preeclampsia. Int. J. Clin. Exp. Pathol.13(3), 382 (2020).
- Qu H-M , QuL-P, LiX-Y, PanX-Z. Overexpressed HO-1 is associated with reduced STAT3 activation in preeclampsia placenta and inhibits STAT3 phosphorylation in placental JEG-3 cells under hypoxia. Arch. Med. Sci.14(3), 597–607 (2018).
- Tong S , Kaitu’u-LinoTUJ, OndaKet al. Heme oxygenase-1 is not decreased in preeclamptic placenta and does not negatively regulate placental soluble fms-like tyrosine kinase-1 or soluble endoglin secretion. Hypertension66(5), 1073–1081 (2015).
- Li J , ZhouJ, YeYet al. Increased heme oxygenase-1 and nuclear factor erythroid 2-related factor-2 in the placenta have a cooperative action on preeclampsia. Gynecol. Obstet. Invest.81(6), 543–551 (2016).
- Kulkarni A , Chavan-GautamP, MehendaleS, YadavH, JoshiS. Global DNA methylation patterns in placenta and its association with maternal hypertension in pre-eclampsia. DNA Cell Biol.30(2), 79–84 (2011).
- White WM , SunZ, BorowskiKSet al. Preeclampsia/eclampsia candidate genes show altered methylation in maternal leukocytes of preeclamptic women at the time of delivery. Hypertens. Pregnancy35(3), 394–404 (2016).
- Kamrani A , AlipourfardI, Ahmadi-KhiaviHet al. The role of epigenetic changes in preeclampsia. Biofactors45(5), 712–724 (2019).
- Zhu X , ZhaoY, HouW, GuoL. miR-153 regulates cardiomyocyte apoptosis by targeting Nrf2/HO-1 signaling. Chromosome Res.27(3), 167–178 (2019).
- Hou W , ZhuX, LiuJ, MapJ. Inhibition of miR-153 ameliorates ischemia/reperfusion-induced cardiomyocytes apoptosis by regulating Nrf2/HO-1 signaling in rats. Biomed. Eng. Online19, 1–14 (2020).
- Ji Q , GaoJ, ZhengYet al. Inhibition of microRNA-153 protects neurons against ischemia/reperfusion injury in an oxygen–glucose deprivation and reoxygenation cellular model by regulating Nrf2/HO-1 signaling. J. Biochem. Mol. Toxicol.31(7), e21905 (2017).
- Hromadnikova I , KotlabovaK, IvankovaK, KroftaL. First trimester screening of circulating C19MC microRNAs and the evaluation of their potential to predict the onset of preeclampsia and IUGR. PLOS ONE12(2), e0171756 (2017).
- Liu Q , QiaoF, ShiX, LiuH, GongX, WuY. Promoter hypomethylation and increased maspin expression in preeclamptic placentas in a Chinese population. Placenta35(11), 876–882 (2014).
- Xie F , WangJ, ZhangB. RefFinder: a web-based tool for comprehensively analyzing and identifying reference genes. Funct. Integr. Genomics23(2), 1–5 (2023).
- Andersen CL , JensenJL, ØrntoftTF. Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets. Cancer Res.64(15), 5245–5250 (2004).
- Vandesompele J , DePreter K, PattynFet al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol.3(7), 1–12 (2002).
- Pfaffl MW , TichopadA, PrgometC, NeuviansTP. Determination of stable housekeeping genes, differentially regulated target genes and sample integrity: bestKeeper–Excel-based tool using pair-wise correlations. Biotechnol. Lett.26, 509–515 (2004).
- Silver N , BestS, JiangJ, TheinSL. Selection of housekeeping genes for gene expression studies in human reticulocytes using real-time PCR. BMC Mol. Biol.7(1), 1–9 (2006).
- Campan M , WeisenbergerDJ, TrinhB, LairdPW. MethyLight. In: DNA Methylation:Methods in Molecular Biology, TostJ (Ed.). Humana Press, lNJ, USA. 325-337. (2009). 10.1007/978-1-59745-522-0_23
- Dreos R , AmbrosiniG, PérierRC, BucherP. The Eukaryotic Promoter Database: expansion of EPDnew and new promoter analysis tools. Nucleic Acids Res.43(D1), D92–D96 (2015).
- Kent WJ , SugnetCW, FureyTSet al. The human genome browser at UCSC. Genome Res.12(6), 996–1006 (2002).
- Edgar R , DomrachevM, LashAE. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res.30(1), 207–210 (2002).
- Hruz T , WyssM, DocquierMet al. RefGenes: identification of reliable and condition specific reference genes for RT-qPCR data normalization. BMC Genom.12, 1–14 (2011).
- Martinez-Fierro M , Garza-VelozI, Carrillo-SanchezKet al. Expression levels of seven candidate genes in human peripheral blood mononuclear cells and their association with preeclampsia. Hypertens. Pregnancy33(2), 191–203 (2014).
- Nakamura M , SekizawaA, PurwosunuYet al. Cellular mRNA expressions of anti-oxidant factors in the blood of preeclamptic women. Prenat. Diagn.29(7), 691–696 (2009).
- Alston MC , RedmanLM, SonesJL. An overview of obesity, cholesterol, and systemic inflammation in preeclampsia. Nutrients14(10), 2087 (2022).
- Medina MV , SapochnikD, GarciaSola M, CosoO. Regulation of the expression of heme oxygenase-1: signal transduction, gene promoter activation, and beyond. Antioxid. Redox. Signal.32(14), 1033–1044 (2020).
- Li H , OuyangY, SadovskyE, ParksWT, ChuT, SadovskyY. Unique microRNA signals in plasma exosomes from pregnancies complicated by preeclampsia. Hypertension75(3), 762–771 (2020).