26
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Classification and Immunotherapy Assessment of Lung Adenocarcinoma Based on Coagulation-Related Genes

, , , , , & ORCID Icon show all
Pages 29-44 | Received 17 Aug 2023, Accepted 31 Oct 2023, Published online: 01 Dec 2023

References

  • Sung H , Ferlay J , Siegel RL et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin. 71(3), 209–249 (2021).
  • Mulder FI , Horvath-Puho E , Van Es N et al. Venous thromboembolism in cancer patients: a population-based cohort study. Blood 137(14), 1959–1969 (2021).
  • Prandoni P , Lensing AW , Piccioli A et al. Recurrent venous thromboembolism and bleeding complications during anticoagulant treatment in patients with cancer and venous thrombosis. Blood 100(10), 3484–3488 (2002).
  • Chew HK , Davies AM , Wun T , Harvey D , Zhou H , White RH . The incidence of venous thromboembolism among patients with primary lung cancer. J. Thromb. Haemost. 6(4), 601–608 (2008).
  • Ruiz-Artacho P , Lecumberri R , Trujillo-Santos J et al. Cancer histology and natural history of patients with lung cancer and venous thromboembolism. Cancers (Basel) 14(17), 4127 (2022).
  • Blann AD , Lip GY . Venous thromboembolism. BMJ 332(7535), 215–219 (2006).
  • Fernandes CJ , Morinaga LTK , Alves JL Jr et al. Cancer-associated thrombosis: the when, how and why. Eur. Respir. Rev. 28(151), (2019).
  • Magnus N , Garnier D , Meehan B et al. Tissue factor expression provokes escape from tumor dormancy and leads to genomic alterations. Proc. Natl Acad. Sci. USA 111(9), 3544–3549 (2014).
  • Monreal M , Lensing AW , Prins MH et al. Screening for occult cancer in patients with acute deep vein thrombosis or pulmonary embolism. J. Thromb. Haemost. 2(6), 876–881 (2004).
  • Zhang W , Ou X , Wu X . Proteomics profiling of plasma exosomes in epithelial ovarian cancer: a potential role in the coagulation cascade, diagnosis and prognosis. Int. J. Oncol. 54(5), 1719–1733 (2019).
  • Shaker H , Bundred NJ , Landberg G et al. Breast cancer stromal clotting activation (tissue factor and thrombin): a pre-invasive phenomena that is prognostic in invasion. Cancer Med. 9(5), 1768–1778 (2020).
  • Desai C , Koupenova M , Machlus KR , Sen Gupta A . Beyond the thrombus: platelet-inspired nanomedicine approaches in inflammation, immune response, and cancer. J. Thromb. Haemost. 20(7), 1523–1534 (2022).
  • Stoiber D , Assinger A . Platelet–leukocyte interplay in cancer development and progression. Cells 9(4), 855 (2020).
  • Agrawal S , Ganguly S , Hajian P , Cao JN , Agrawal A . PDGF upregulates CLEC-2 to induce T regulatory cells. Oncotarget 6(30), 28621–28632 (2015).
  • NIH. National Cancer Institute. National GDC Portal . Harmonized Cancer Datasets. Genomic Data Commons Data Portal. https://portal.gdc.cancer.gov/
  • NCBI.Gene Expression Omnibus (GEO) . www.ncbi.nlm.nih.gov/geo/
  • He Q , Yang J , Jin Y . Immune infiltration and clinical significance analyses of the coagulation-related genes in hepatocellular carcinoma. Brief. Bioinform. 23(4), (2022).
  • KEGG: Kyoto Encyclopedia of Genes and Genomes . www.genome.jp/kegg/
  • Robinson MD , Mccarthy DJ , Smyth GK . edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics (Oxford, England) 26(1), 139–140 (2010).
  • STRING.Protein-Protein Interaction Networks Functional Enrichment Analysis . https://cn.string-db.org/cgi/input.pl
  • Zhang H , Meltzer P , Davis S . RCircos: an R package for Circos 2D track plots. BMC Bioinformatics 14, 244 (2013).
  • Skidmore ZL , Wagner AH , Lesurf R et al. GenVisR: genomic visualizations in R. Bioinformatics (Oxford, England) 32(19), 3012–3014 (2016).
  • Yu G , Wang LG , Han Y , He QY . clusterProfiler: an R package for comparing biological themes among gene clusters. Omics 16(5), 284–287 (2012).
  • Terry M. Therneau PMG . Modeling Survival Data: Extending the Cox Model. Springer, NY, USA (2000).
  • Hanzelmann S , Castelo R , Guinney J . GSVA: gene set variation analysis for microarray and RNA-seq data. BMC Bioinformatics 14, 7 (2013).
  • Yoshihara K , Shahmoradgoli M , Martinez E et al. Inferring tumour purity and stromal and immune cell admixture from expression data. Nat. Commun. 4, 2612 (2013).
  • Liu J , Shen H , Gu W et al. Prediction of prognosis, immunogenicity and efficacy of immunotherapy based on glutamine metabolism in lung adenocarcinoma. Front. Immunol. 13, 960738 (2022).
  • TCIA. The Cancer Immunome Atlas . https://tcia.at
  • TIDE . http://tide.dfci.harvard.edu/login/
  • Chew HK , Wun T , Harvey D , Zhou H , White RH . Incidence of venous thromboembolism and its effect on survival among patients with common cancers. Arch. Intern. Med. 166(4), 458–464 (2006).
  • Timp JF , Braekkan SK , Versteeg HH , Cannegieter SC . Epidemiology of cancer-associated venous thrombosis. Blood 122(10), 1712–1723 (2013).
  • Mahajan A , Brunson A , Adesina O , Keegan THM , Wun T . The incidence of cancer-associated thrombosis is increasing over time. Blood Adv. 6(1), 307–320 (2022).
  • Tsubata Y , Hotta T , Hamai K et al. A new risk-assessment tool for venous thromboembolism in advanced lung cancer: a prospective, observational study. J. Hematol. Oncol. 15(1), 40 (2022).
  • Dvorak HF . Tumors: wounds that do not heal-a historical perspective with a focus on the fundamental roles of increased vascular permeability and clotting. Semin. Thromb. Hemost. 45(6), 576–592 (2019).
  • Burzynski LC , Humphry M , Pyrillou K et al. The coagulation and immune systems are directly linked through the activation of interleukin-1alpha by thrombin. Immunity 50(4), 1033–1042; e1036 (2019).
  • Esmon CT . Inflammation and thrombosis. J. Thromb. Haemost. 1(7), 1343–1348 (2003).
  • Tsukamoto J , Monteiro M , Vale S et al. Thromboembolic events related to treatment with checkpoint inhibitors: report of two cases. Case Rep. Oncol. 11(3), 648–653 (2018).
  • Boutros C , Scoazec JY , Mateus C , Routier E , Roy S , Robert C . Arterial thrombosis and anti-PD-1 blockade. Eur. J. Cancer 91, 164–166 (2018).
  • Horio Y , Takamatsu K , Tamanoi D et al. Trousseau’s syndrome triggered by an immune checkpoint blockade in a non-small cell lung cancer patient. Eur. J. Immunol. 48(10), 1764–1767 (2018).
  • Holmes VA . Changes in haemostasis during normal pregnancy: does homocysteine play a role in maintaining homeostasis? Proc. Nutr. Soc. 62(2), 479–493 (2003).
  • Xu D , Xu R , He L et al. Comparison of pathogenic mechanisms underlying single and recurrent venous thromboembolism based on gene expression profiling. Ann. Vasc. Surg. 36, 252–259 (2016).
  • Wang Z , Lu Z , Lin S et al. Leucine-tRNA-synthase-2-expressing B cells contribute to colorectal cancer immunoevasion. Immunity 55(6), 1067–1081; e1068 (2022).
  • Cochran BJ , Ong KL , Manandhar B , Rye KA . APOA1: a protein with multiple therapeutic functions. Curr. Atheroscler. Rep. 23(3), 11 (2021).
  • Sun Y , Ren D , Yang C et al. TRIM15 promotes the invasion and metastasis of pancreatic cancer cells by mediating APOA1 ubiquitination and degradation. Biochim. Biophys. Acta Mol. Basis Dis. 1867(11), 166213 (2021).
  • Ochieng J , Nangami G , Sakwe A et al. Impact of fetuin-A (AHSG) on tumor progression and type 2 diabetes. Int. J. Mol. Sci. 19(8), (2018).
  • Niu L , Song X , Wang N , Xue L , Song X , Xie L . Tumor-derived exosomal proteins as diagnostic biomarkers in non-small cell lung cancer. Cancer Sci. 110(1), 433–442 (2019).
  • Borgquist S , Butt T , Almgren P et al. Apolipoproteins, lipids and risk of cancer. Int. J. Cancer 138(11), 2648–2656 (2016).
  • Batsuli G , Kouides P . Rare coagulation factor deficiencies (factors VII, X, V, and II). Hematol. Oncol. Clin. North Am. 35(6), 1181–1196 (2021).
  • Bayleyegn B , Adane T , Getawa S , Aynalem M , Kifle ZD . Coagulation parameters in lung cancer patients: a systematic review and meta-analysis. J. Clin. Lab. Anal. 36(7), e24550 (2022).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.