Selection of target-binding proteins from the information of weakly enriched phage display libraries by deep sequencing and machine learning

Tomoyuki Itoa Department of Biomolecular Engineering, Graduate School of Engineering, Tohoku University, Sendai, JapanView further author information

Thuy Duong Nguyenb Artificial Intelligence Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, JapanView further author information

Yutaka Saitob Artificial Intelligence Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan;c AIST-Waseda University Computational Bio Big-Data Open Innovation Laboratory (CBBD-OIL), Tokyo, Japan;d Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan;e Center for Advanced Intelligence Project, RIKEN, Tokyo, JapanView further author information

Yoichi Kurumidab Artificial Intelligence Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, JapanView further author information

Hikaru Nakazawaa Department of Biomolecular Engineering, Graduate School of Engineering, Tohoku University, Sendai, JapanView further author information

Sakiya Kawadaa Department of Biomolecular Engineering, Graduate School of Engineering, Tohoku University, Sendai, JapanView further author information

Hafumi Nishif Department of Applied Information Sciences, Graduate School of Information Sciences, Tohoku University, Sendai, Japan;g Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan;h Faculty of Core Research, Ochanomizu University, Tokyo, JapanView further author information

Koji Tsudad Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan;e Center for Advanced Intelligence Project, RIKEN, Tokyo, Japan;i Research and Services Division of Materials Data and Integrated Systems, National Institute for Materials Science, Tsukuba, JapanView further author information

Tomoshi Kamedab Artificial Intelligence Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan;e Center for Advanced Intelligence Project, RIKEN, Tokyo, JapanCorrespondence[email protected]

https://orcid.org/0000-0001-9508-5366 View further author information

Mitsuo Umetsua Department of Biomolecular Engineering, Graduate School of Engineering, Tohoku University, Sendai, Japan;e Center for Advanced Intelligence Project, RIKEN, Tokyo, JapanCorrespondence[email protected]

https://orcid.org/0000-0003-4390-0263 View further author information

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Selection of target-binding proteins from the information of weakly enriched phage display libraries by deep sequencing and machine learning

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