High-throughput optofluidic screening of single B cells identifies novel cross-reactive antibodies as inhibitors of uPAR with antibody-dependent effector functions

André Luiz Lourençoa Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, USAView further author information

Shih-Wei Chuoa Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, USAView further author information

Markus F. Bohna Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, USAView further author information

Byron Hannb Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USAView further author information

Shireen Khanc ChemPartner, South San Francisco, California, USAView further author information

Neha Yevalekarc ChemPartner, South San Francisco, California, USAView further author information

Nitin Patelc ChemPartner, South San Francisco, California, USAView further author information

Teddy Yangd Shanghai ChemPartner Co Ltd, Shanghai, ChinaView further author information

Lina Xud Shanghai ChemPartner Co Ltd, Shanghai, ChinaView further author information

Dandan Lvd Shanghai ChemPartner Co Ltd, Shanghai, ChinaView further author information

Robert Drakase ShangPharma Innovation Inc, South San Francisco, California, USAView further author information

Sarah Livelyc ChemPartner, South San Francisco, California, USAView further author information

Charles S. Craika Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, USA;b Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USACorrespondence[email protected]

https://orcid.org/0000-0001-7704-9185 View further author information

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High-throughput optofluidic screening of single B cells identifies novel cross-reactive antibodies as inhibitors of uPAR with antibody-dependent effector functions

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High-throughput optofluidic screening of single B cells identifies novel cross-reactive antibodies as inhibitors of uPAR with antibody-dependent effector functions

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