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Improved antibody pharmacokinetics by disruption of contiguous positive surface potential and charge reduction using alternate human framework

Romain OllierResearch, AC Immune SA, Lausanne, SwitzerlandCorrespondence[email protected]
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Aline FuchsResearch, AC Immune SA, Lausanne, SwitzerlandView further author information

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Florence GauyeResearch, AC Immune SA, Lausanne, SwitzerlandView further author information

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Katarzyna PiorkowskaResearch, AC Immune SA, Lausanne, SwitzerlandView further author information

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Sébastien MenantResearch, AC Immune SA, Lausanne, SwitzerlandView further author information

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Monisha RatnamResearch, AC Immune SA, Lausanne, SwitzerlandView further author information

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Paolo MontanariResearch, AC Immune SA, Lausanne, SwitzerlandView further author information

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Florence GuilhotResearch, AC Immune SA, Lausanne, SwitzerlandView further author information

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Didier PhillipeResearch, AC Immune SA, Lausanne, SwitzerlandView further author information

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Mickael AudrainResearch, AC Immune SA, Lausanne, SwitzerlandView further author information

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Anne-Laure EgesipeResearch, AC Immune SA, Lausanne, SwitzerlandView further author information

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Damien NévoltrisResearch, AC Immune SA, Lausanne, SwitzerlandView further author information

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Tamara SeredeninaResearch, AC Immune SA, Lausanne, SwitzerlandView further author information

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Andrea PfeiferResearch, AC Immune SA, Lausanne, SwitzerlandView further author information

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Marie Kosco-VilboisResearch, AC Immune SA, Lausanne, SwitzerlandView further author information

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Tariq AfrozResearch, AC Immune SA, Lausanne, SwitzerlandCorrespondence[email protected]
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