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mAbs Volume 15, 2023 - Issue 1
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Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibition

Britta Lipinskia Antibody Discovery and Protein Engineering (ADPE), Merck Healthcare KGaA, Darmstadt, Germany;b Institute for Organic Chemistry and Biochemistry, Technical University of Darmstadt, Darmstadt, GermanyView further author information
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Laura Unmuthc Early Protein Supply and Characterization (EPSC), Merck Healthcare KGaA, Darmstadt, GermanyView further author information
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Paul Arrasa Antibody Discovery and Protein Engineering (ADPE), Merck Healthcare KGaA, Darmstadt, GermanyView further author information
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Stefan Beckerc Early Protein Supply and Characterization (EPSC), Merck Healthcare KGaA, Darmstadt, GermanyView further author information
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Christina Bauera Antibody Discovery and Protein Engineering (ADPE), Merck Healthcare KGaA, Darmstadt, GermanyView further author information
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Lars Toleikisc Early Protein Supply and Characterization (EPSC), Merck Healthcare KGaA, Darmstadt, GermanyView further author information
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Simon Kraha Antibody Discovery and Protein Engineering (ADPE), Merck Healthcare KGaA, Darmstadt, GermanyView further author information
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Achim Doernera Antibody Discovery and Protein Engineering (ADPE), Merck Healthcare KGaA, Darmstadt, GermanyView further author information
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Desislava Yanakievaa Antibody Discovery and Protein Engineering (ADPE), Merck Healthcare KGaA, Darmstadt, GermanyView further author information
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Ammelie Svea Bojed Division of Antibody-Based Immunotherapy, Department of Internal Medicine II, University Hospital Schleswig-Holstein and Christian-Albrechts-University Kiel, Kiel, GermanyView further author information
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Katja Klauszd Division of Antibody-Based Immunotherapy, Department of Internal Medicine II, University Hospital Schleswig-Holstein and Christian-Albrechts-University Kiel, Kiel, GermanyView further author information
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Matthias Peippd Division of Antibody-Based Immunotherapy, Department of Internal Medicine II, University Hospital Schleswig-Holstein and Christian-Albrechts-University Kiel, Kiel, GermanyView further author information
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Vanessa Siegmundc Early Protein Supply and Characterization (EPSC), Merck Healthcare KGaA, Darmstadt, GermanyView further author information
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Andreas Eversa Antibody Discovery and Protein Engineering (ADPE), Merck Healthcare KGaA, Darmstadt, GermanyView further author information
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Harald Kolmarb Institute for Organic Chemistry and Biochemistry, Technical University of Darmstadt, Darmstadt, GermanyView further author information
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Lukas Pekara Antibody Discovery and Protein Engineering (ADPE), Merck Healthcare KGaA, Darmstadt, GermanyORCID Iconhttps://orcid.org/0000-0001-9259-0965View further author information
ORCID Icon &
Stefan Zielonkaa Antibody Discovery and Protein Engineering (ADPE), Merck Healthcare KGaA, Darmstadt, Germany;b Institute for Organic Chemistry and Biochemistry, Technical University of Darmstadt, Darmstadt, GermanyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-4649-2843View further author information
ORCID Icon show all
Article: 2236265 | Received 02 Apr 2023, Accepted 10 Jul 2023, Published online: 19 Jul 2023

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