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mAbs Volume 15, 2023 - Issue 1
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A library approach for the de novo high-throughput isolation of humanized VHH domains with favorable developability properties following camelid immunization

Paul Arrasa Antibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, Germany;b Institute for Organic Chemistry and Biochemistry, Technical University of Darmstadt, Darmstadt, GermanyView further author information
,
Han Byul Yooa Antibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, Germany;c Early Protein Supply & Characterization, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
,
Lukas Pekara Antibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
,
Christian Schröterd ADCs & Targeted NBE Therapeutics, Merck KGaA, Darmstadt, GermanyView further author information
,
Thomas Clarkee Bioinformatics, EMD Serono, Billerica, MA, USAView further author information
,
Simon Kraha Antibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
,
Daniel Klewinghausc Early Protein Supply & Characterization, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
,
Vanessa Siegmundc Early Protein Supply & Characterization, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
,
Andreas Eversa Antibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, GermanyCorrespondence[email protected]
View further author information
&
Stefan Zielonkaa Antibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, Germany;b Institute for Organic Chemistry and Biochemistry, Technical University of Darmstadt, Darmstadt, GermanyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-4649-2843View further author information
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Article: 2261149 | Received 27 May 2023, Accepted 15 Sep 2023, Published online: 27 Sep 2023

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