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Research Article

DNA methylation marker identification and poly-methylation risk score in prediction of healthspan termination

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Pages 461-472 | Received 30 Sep 2023, Accepted 08 Feb 2024, Published online: 14 Mar 2024
Supplemental material

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Supplementary Materials and Methods

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Supplementary Table 1. The List of health span composition and Their ICD-10 Codes and The source of Their GWAS

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Supplementary Table 2. Baseline characteristics of participants with or without terminated health span.

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Supplementary Table 3. Two hundred seventy-four DNA methylation marks associated with HST

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Supplementary Table 4. The subgroup associations analysis of Fifty-nine methylation-HST associations for CpG sites with eight outcomes of HST

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Supplementary Table 5. Functional enrichment analysis of CpGs that were associated with HST

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Supplementary Table 6. Associations between methylation levels of HST associated CpG sites and expression of ±500kb genes in white blood cells in the ADNI chorot study

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Supplementary Table 7. Associations between genetically predicted mRNA expression levels with HST risk

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Supplementary Table 8. Associations of PMRS with cause-specific incidenc

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Supplementary Table 9. 59 HST-associated CpGs information in EWAS Atlas

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