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Research Article

hsa_circ_0087100/hsa-miR-6743-5p affects Th1 cell differentiation by regulating STAT1 in diabetic retinopathy

Shuai He1 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China;3 National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science & Photomedicine, Shanghai Engineering Center for Precise Diagnosis & Treatment of Eye Diseases, Shanghai, PR China

Dongwei Lai1 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China;3 National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science & Photomedicine, Shanghai Engineering Center for Precise Diagnosis & Treatment of Eye Diseases, Shanghai, PR China

Chenggong Ma4 Xiangya School of Medicine, Central South University, Changsha, Hunan, PR China

Chunren Meng1 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China;3 National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science & Photomedicine, Shanghai Engineering Center for Precise Diagnosis & Treatment of Eye Diseases, Shanghai, PR China

Chunyang Cai1 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China;3 National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science & Photomedicine, Shanghai Engineering Center for Precise Diagnosis & Treatment of Eye Diseases, Shanghai, PR China

Qian Chen2 Department of Ophthalmology, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR ChinaCorrespondence[email protected]

Chufeng Gu1 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China;3 National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science & Photomedicine, Shanghai Engineering Center for Precise Diagnosis & Treatment of Eye Diseases, Shanghai, PR ChinaCorrespondence[email protected]

Qinghua Qiu2 Department of Ophthalmology, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR ChinaCorrespondence[email protected]

https://orcid.org/0000-0002-8383-892X

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hsa_circ_0087100/hsa-miR-6743-5p affects Th1 cell differentiation by regulating STAT1 in diabetic retinopathy

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Supplemental Table 1. Details of circRNA, miRNA and mRNA datasets of DR patients and healthy controls.

Supplemental Table 2. Sequence of primers used for RT-qPCR.

Supplemental Table 3. Top 10 GO enrichment terms of differentially expressed genes.

Supplemental Table 4. Top 10 KEGG enrichment terms of differentially expressed genes.

Supplemental Table 5. Details of hub genes in the ceRNA network from GEO datasets.

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hsa_circ_0087100/hsa-miR-6743-5p affects Th1 cell differentiation by regulating STAT1 in diabetic retinopathy

Supplemental figure

Supplemental figure

Supplemental figure

Supplemental figure

Supplemental figure

Supplemental figure

Supplemental figure

Supplemental figure

Supplemental Table 1. Details of circRNA, miRNA and mRNA datasets of DR patients and healthy controls.

Supplemental Table 2. Sequence of primers used for RT-qPCR.

Supplemental Table 3. Top 10 GO enrichment terms of differentially expressed genes.

Supplemental Table 4. Top 10 KEGG enrichment terms of differentially expressed genes.

Supplemental Table 5. Details of hub genes in the ceRNA network from GEO datasets.

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