Pharmaceutical Development and Technology, Volume 22, Issue 6 (2017)

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Pharmaceutical Development and Technology, Volume 22, Issue 6 (2017)

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Issue Theme: Pharmaceutical process optimisation and formulation development

Research Article

Article
Formulation and process considerations for the design of sildenafil-loaded polymeric microparticles by vibrational spray-drying
Moritz Beck-Broichsitter, Adam Bohr, Leticia Aragão-Santiago, Andreas Klingl & Thomas Kissel
Pages: 691-698
Published online: 07 Jan 2016
AbstractforFormulation and process considerations for the design of sildenafil-loaded polymeric microparticles by vibrational spray-drying | Full Text | References | PDF (1.1 MB)
  • 265 Views
  • 13 CrossRef citations
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Article
Monitoring the concentration of flowing pharmaceutical powders in a tableting feed frame
Ryan Gosselin, Pedro Durão, Nicolas Abatzoglou & Jean-Maxime Guay
Pages: 699-705
Published online: 28 Oct 2015
AbstractforMonitoring the concentration of flowing pharmaceutical powders in a tableting feed frame | Full Text | References | PDF (1.4 MB)
  • 293 Views
  • 28 CrossRef citations
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Article
Design and evaluation of gamma-sterilized vancomycin hydrochloride-loaded poly(ɛ-caprolactone) microspheres for the treatment of biofilm-based medical device-related osteomyelitis
Elif Sarıgöl, Sibel Bozdağ Pehlivan, Melike Ekizoğlu, Meral Sağıroğlu & Sema Çalış
Pages: 706-714
Published online: 26 Oct 2015
AbstractforDesign and evaluation of gamma-sterilized vancomycin hydrochloride-loaded poly(ɛ-caprolactone) microspheres for the treatment of biofilm-based medical device-related osteomyelitis | Full Text | References | PDF (1.2 MB)
  • 420 Views
  • 9 CrossRef citations
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Article
Impact of moisture and magnesium stearate functionality on manufacturability of wet granulated metformin tablets
Umesh Kestur, Divyakant Desai, Shasad Sharif, Benjamin Wong, Hang Guo, Dan Tang & Steven Chan
Pages: 715-723
Published online: 29 Nov 2015
AbstractforImpact of moisture and magnesium stearate functionality on manufacturability of wet granulated metformin tablets | Full Text | References | PDF (827.8 KB)
  • 538 Views
  • 3 CrossRef citations
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Article
The effect of freeze-dried antibody concentrations on its stability in the presence of trehalose and hydroxypropyl-β-cyclodextrin: a Box–Behnken statistical design
Homa Faghihi, Fatemeh Khalili, Mohsen Amini & Alireza Vatanara
Pages: 724-732
Published online: 10 Dec 2015
AbstractforThe effect of freeze-dried antibody concentrations on its stability in the presence of trehalose and hydroxypropyl-β-cyclodextrin: a Box–Behnken statistical design | Full Text | References | PDF (2 MB)
  • 260 Views
  • 8 CrossRef citations
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Article
Systemic delivery of parathyroid hormone (1–34) using spray freeze-dried inhalable particles
Narges Poursina, Alireza Vatanara, Mohammad Reza Rouini, Kambiz Gilani & Abdolhossein Rouholamini Najafabadi
Pages: 733-739
Published online: 27 Dec 2015
AbstractforSystemic delivery of parathyroid hormone (1–34) using spray freeze-dried inhalable particles | Full Text | References | PDF (676.5 KB)
  • 242 Views
  • 21 CrossRef citations
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Article
Investigation of the combined effect of MgO and PEG on the release profile of mefenamic acid prepared via hot-melt extrusion techniques
Sultan M. Alshehri, Roshan V. Tiwari, Bader B. Alsulays, Eman A. Ashour, Abdullah S. Alshetaili, Bjad Almutairy, Jun-Bom Park, Joseph Morott, Bhupinder Sandhu, Soumyajit Majumdar & Michael A. Repka
Pages: 740-753
Published online: 29 Jan 2016
AbstractforInvestigation of the combined effect of MgO and PEG on the release profile of mefenamic acid prepared via hot-melt extrusion techniques | Full Text | References | PDF (3.9 MB)
  • 148 Views
  • 10 CrossRef citations
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Article
Enhancement of solubility and antidiabetic effects of Repaglinide using spray drying technique in STZ-induced diabetic rats
Jaleh Varshosaz, Mohsen Minayian, Mahdieh Ahmadi & Erfaneh Ghassami
Pages: 754-763
Published online: 19 Feb 2016
AbstractforEnhancement of solubility and antidiabetic effects of Repaglinide using spray drying technique in STZ-induced diabetic rats | Full Text | References | PDF (1,010.7 KB)
  • 147 Views
  • 11 CrossRef citations
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Article
MCC–mannitol mixtures after roll compaction/dry granulation: percolation thresholds for ribbon microhardness and granule size distribution
Ana Pérez Gago & Peter Kleinebudde
Pages: 764-774
Published online: 07 Apr 2016
AbstractforMCC–mannitol mixtures after roll compaction/dry granulation: percolation thresholds for ribbon microhardness and granule size distribution | Full Text | References | PDF (2.6 MB)
  • 3667 Views
  • 6 CrossRef citations
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Open Access
Article
Nano drug delivery systems and gamma radiation sterilization
F. Sakar, A. Y. Özer, S. Erdogan, M. Ekizoglu, D. Kart, M. Özalp, S. Colak & Y. Zencir
Pages: 775-784
Published online: 06 Apr 2016
AbstractforNano drug delivery systems and gamma radiation sterilization | Full Text | References | PDF (2.7 MB)
  • 426 Views
  • 21 CrossRef citations
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Article
Lack of a synergistic effect of arginine–glutamic acid on the physical stability of spray-dried bovine serum albumin
Mouhamad Reslan, Yusuf K. Demir, Bernhardt L. Trout, Hak-Kim Chan & Veysel Kayser
Pages: 785-791
Published online: 19 May 2016
AbstractforLack of a synergistic effect of arginine–glutamic acid on the physical stability of spray-dried bovine serum albumin | Full Text | References | PDF (1.3 MB)
  • 271 Views
  • 11 CrossRef citations
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Article
Formulation and characterization of Turkish oregano microcapsules prepared by spray-drying technology
Juste Baranauskaite, Liudas Ivanauskas, Ruta Masteikova, Dalia Kopustinskiene, Algirdas Baranauskas & Jurga Bernatoniene
Pages: 792-803
Published online: 02 Jun 2016
AbstractforFormulation and characterization of Turkish oregano microcapsules prepared by spray-drying technology | Full Text | References | PDF (2 MB)
  • 347 Views
  • 15 CrossRef citations
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Article
The application of crystallization in the presence of additives to enable drug-in-capsule technology
Yildiz Yilmaz, Faraj Atassi & Manuel Sanchez-Felix
Pages: 804-808
Published online: 08 Jun 2016
AbstractforThe application of crystallization in the presence of additives to enable drug-in-capsule technology | Full Text | References | PDF (995.7 KB)
  • 161 Views
  • 1 CrossRef citations
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Article
Design and in vitro characterization of ivermectin nanocrystals liquid formulation based on a top–down approach
Walter Javier Starkloff, Verónica Bucalá, Santiago Daniel Palma & Noelia L. Gonzalez Vidal
Pages: 809-817
Published online: 27 Jun 2016
AbstractforDesign and in vitro characterization of ivermectin nanocrystals liquid formulation based on a top–down approach | Full Text | References | PDF (1.7 MB)
  • 247 Views
  • 13 CrossRef citations
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Article
A mixed solvent system for preparation of spherically agglomerated crystals of ascorbic acid
Fuzheng Ren, Yaru Zhou, Yan Liu, Jinping Fu, Qiufang Jing & Guobin Ren
Pages: 818-826
Published online: 12 Jul 2016
AbstractforA mixed solvent system for preparation of spherically agglomerated crystals of ascorbic acid | Full Text | References | PDF (1.5 MB)
  • 95 Views
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Article
Evaluation of the effect of some additives on the efficiency of binder liquid in wet agglomeration of crystals
Maryam Maghsoodi, Hassan Nabizadeh & Ali Nokhodchi
Pages: 827-835
Published online: 07 Jul 2016
AbstractforEvaluation of the effect of some additives on the efficiency of binder liquid in wet agglomeration of crystals | Full Text | References | PDF (1.6 MB)
  • 59 Views
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Article
Preparation of a reproducible long-acting formulation of risperidone-loaded PLGA microspheres using microfluidic method
Elham Jafarifar, Marziyeh Hajialyani, Mona Akbari, Masoud Rahimi, Yalda Shokoohinia & Ali Fattahi
Pages: 836-843
Published online: 08 Sep 2016
AbstractforPreparation of a reproducible long-acting formulation of risperidone-loaded PLGA microspheres using microfluidic method | Full Text | References | PDF (1 MB)
  • 653 Views
  • 19 CrossRef citations
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Article
In vitro aerodynamic characteristics of aerosol delivered from different inhalation methods in mechanical ventilation
Muhammad H. E. ElHansy, Marina E. Boules, Heba Farid, Henry Chrystyn, Sameh Kamal El-Maraghi, Mohamed Bakry Al-Kholy, Assem Fouad Mohamed El-Essawy, Maha M. Abdelrahman, Amira S. A. Said, Raghda R. S. Hussein, Hoda Rabea & Mohamed E. A. Abdelrahim
Pages: 844-849
Published online: 30 Aug 2016
AbstractforIn vitro aerodynamic characteristics of aerosol delivered from different inhalation methods in mechanical ventilation | Full Text | References | PDF (772.8 KB)
  • 239 Views
  • 30 CrossRef citations
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