Pharmaceutical Development and Technology, Volume 23, Issue 3 (2018)

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Pharmaceutical Development and Technology, Volume 23, Issue 3 (2018)

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Issue Theme: Ocular, otic, nasal, rectal and vaginal formulation innovations and regulatory considerations

Editorial

Editorial
Ocular, otic, nasal, rectal and vaginal formulation innovations and regulatory considerations
Raid Alany
Page: 217
Published online: 24 Jan 2018
CitationforOcular, otic, nasal, rectal and vaginal formulation innovations and regulatory considerations | Full Text | PDF (92.1 KB)
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Free Access

Ocular

Article
Preparation of dexamethasone ophthalmic implants: a comparative study of in vitro release profiles
Ana I. Prata, Patrícia Coimbra & M. Eugénia Pina
Pages: 218-224
Published online: 30 Mar 2017
AbstractforPreparation of dexamethasone ophthalmic implants: a comparative study of in vitro release profiles | Full Text | References | PDF (1.7 MB)
  • 238 Views
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Article
Determination and application of the permitted daily exposure (PDE) for topical ocular drugs in multipurpose manufacturing facilities
Ester Lovsin Barle, Jean-Claude Bizec, Milica Glogovac, Kamila Gromek & Gian Christian Winkler
Pages: 225-230
Published online: 12 Apr 2017
AbstractforDetermination and application of the permitted daily exposure (PDE) for topical ocular drugs in multipurpose manufacturing facilities | Full Text | References | PDF (576.7 KB)
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Article
Increasing efficacy and reducing systemic absorption of brimonidine tartrate ophthalmic gels in rabbits
Xiaochen Pang, Jiawei Li, Jiaxin Pi, Dongli Qi, Pan Guo, Nan Li, Yumei Wu & Zhidong Liu
Pages: 231-239
Published online: 31 May 2017
AbstractforIncreasing efficacy and reducing systemic absorption of brimonidine tartrate ophthalmic gels in rabbits | Full Text | References | PDF (1.2 MB)
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Article
Aceclofenac oil drops: characterization and evaluation against ocular inflammation
Rajesh Katara, Sameer Sachdeva & Dipak K. Majumdar
Pages: 240-246
Published online: 19 Jun 2017
AbstractforAceclofenac oil drops: characterization and evaluation against ocular inflammation | Full Text | References | PDF (934.5 KB)
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Note
Profiling extractable and leachable inorganic impurities in ophthalmic drug containers by ICP-MS
Paige Solomon & Jenny Nelson
Pages: 247-254
Published online: 24 Aug 2017
AbstractforProfiling extractable and leachable inorganic impurities in ophthalmic drug containers by ICP-MS | Full Text | References | PDF (1.1 MB)
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Report
Medicated ocular bandages and corneal health: potential excipients and active pharmaceutical ingredients
Ghada Zidan, Ilva D. Rupenthal, Carol Greene & Ali Seyfoddin
Pages: 255-260
Published online: 21 Sep 2017
AbstractforMedicated ocular bandages and corneal health: potential excipients and active pharmaceutical ingredients | Full Text | References | PDF (611.1 KB)
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Otic

Report
Topical otic drugs in a multi-purpose manufacturing facility: a guide on determination and application of permitted daily exposure (PDE)
Lisa Wiesner, Maarten Prause & Ester Lovsin Barle
Pages: 261-264
Published online: 07 Jun 2017
AbstractforTopical otic drugs in a multi-purpose manufacturing facility: a guide on determination and application of permitted daily exposure (PDE) | Full Text | References | PDF (372.2 KB)
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Nasal

Article
Revisiting the role of sucrose in PLGA-PEG nanocarrier for potential intranasal delivery
A. Bonaccorso, T. Musumeci, C. Carbone, L. Vicari, M. Rosaria Lauro & G. Puglisi
Pages: 265-274
Published online: 22 Feb 2017
AbstractforRevisiting the role of sucrose in PLGA-PEG nanocarrier for potential intranasal delivery | Full Text | References | PDF (1.9 MB) | Supplemental
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Article
Metoclopramide nasal spray in vitro evaluation and in vivo pharmacokinetic studies in dogs
Ying Li, Xianpeng Fan, Wanqing Li, Peng Yang, Hui Zhang, Daoquan Tang, Xiaoxin Yin, Jianxu Sun & Aiping Zheng
Pages: 275-281
Published online: 26 Apr 2017
AbstractforMetoclopramide nasal spray in vitro evaluation and in vivo pharmacokinetic studies in dogs | Full Text | References | PDF (932.6 KB)
  • 336 Views
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Review Article
Intranasal drug delivery devices and interventions associated with post-operative endoscopic sinus surgery
Lari K. Dkhar, Jim Bartley, David White & Ali Seyfoddin
Pages: 282-294
Published online: 02 Nov 2017
AbstractforIntranasal drug delivery devices and interventions associated with post-operative endoscopic sinus surgery | Full Text | References | PDF (1.5 MB)
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Rectal

Article
Development of the rectal dosage form with silver-coated glass beads for local-action applications in lower sections of the gastrointestinal tract
Krzysztof Siczek, Jakub Fichna, Hubert Zatorski, Bożena Karolewicz, Leszek Klimek & Artur Owczarek
Pages: 295-300
Published online: 03 Aug 2017
AbstractforDevelopment of the rectal dosage form with silver-coated glass beads for local-action applications in lower sections of the gastrointestinal tract | Full Text | References | PDF (1.3 MB)
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Vaginal

Article
Design and in vitro evaluation of tenofovir-loaded vaginal gels for the prevention of HIV infections
Selin Seda Timur, Adem Şahin, Eren Aytekin, Naile Öztürk, Kerem Heybet Polat, Nurten Tezel, Reyhan Neslihan Gürsoy & Sema Çalış
Pages: 301-310
Published online: 29 May 2017
AbstractforDesign and in vitro evaluation of tenofovir-loaded vaginal gels for the prevention of HIV infections | Full Text | References | PDF (1.3 MB)
  • 511 Views
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Report
Vaginal film for prevention of HIV: using visual and tactile evaluations among potential users to inform product design
K. M. Guthrie, L. Rohan, R. K. Rosen, S. E. Vargas, J. G. Shaw, D. Katz, E. M. Kojic, A. S. Ham, D. Friend, K. W. Buckheit & R. W. Buckheit Jr.
Pages: 311-314
Published online: 21 Jun 2017
AbstractforVaginal film for prevention of HIV: using visual and tactile evaluations among potential users to inform product design | Full Text | References | PDF (765.4 KB)
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