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Volume 28, Issue 2

Journal of Biopharmaceutical Statistics

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Journal of Biopharmaceutical Statistics, Volume 28, Issue 2 (2018)

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Journal of Biopharmaceutical Statistics, Volume 28, Issue 2 (2018)

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Vol 34, 2024 Vol 33, 2023 Vol 32, 2022 Vol 31, 2021 Vol 30, 2020 Vol 29, 2019 Volume 28, 2018 Vol 27, 2017 Vol 26, 2016 Vol 25, 2015 Vol 24, 2014 Vol 23, 2013 Vol 22, 2012 Vol 21, 2010-2011 Vol 20, 2009-2010 Vol 19, 2009 Vol 18, 2007-2008 Vol 17, 2007 Vol 16, 2006 Vol 15, 2005 Vol 14, 2004 Vol 13, 2003 Vol 12, 2002 Vol 11, 2001 Vol 10, 2000 Vol 9, 1999 Vol 8, 1998 Vol 7, 1997 Vol 6, 1996 Vol 5, 1995 Vol 4, 1994 Vol 3, 1993 Vol 2, 1992 Vol 1, 1991

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Special Issue: Precision Medicine in Cancer Research

Guest Editors’ Note

Article

Statistical issues and advances in cancer precision medicine research

Marlina D. Nasution & Xiaofei Wang

Pages: 215-216

Published online: 07 Mar 2018

CitationforStatistical issues and advances in cancer precision medicine research | Full Text | References | PDF (234.6 KB)

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Original Articles

Article

Definitions and statistical properties of master protocols for personalized medicine in oncology

Lindsay A. Renfro & Sumithra J. Mandrekar

Pages: 217-228

Published online: 09 Oct 2017

AbstractforDefinitions and statistical properties of master protocols for personalized medicine in oncology | Full Text | References | PDF (1.2 MB)

855 Views
22 CrossRef citations
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Reviews

Review

Advancing cancer drug development through precision medicine and innovative designs

Weidong Zhang, Jing Wang & Sandeep Menon

Pages: 229-244

Published online: 27 Nov 2017

AbstractforAdvancing cancer drug development through precision medicine and innovative designs | Full Text | References | PDF (1.2 MB)

552 Views
1 CrossRef citations
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Original Articles

Article

New designs for basket clinical trials in oncology

Richard Simon

Pages: 245-255

Published online: 30 Oct 2017

AbstractforNew designs for basket clinical trials in oncology | Full Text | References | PDF (1.1 MB)

1116 Views
23 CrossRef citations
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Article

Phase II cancer clinical trials for biomarker-guided treatments

Sin-Ho Jung

Pages: 256-263

Published online: 27 Nov 2017

AbstractforPhase II cancer clinical trials for biomarker-guided treatments | Full Text | References | PDF (622.8 KB)

260 Views
2 CrossRef citations
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Article

Quantitative assessment of a prognostic or predictive biomarker panel

Edward L. Korn & Boris Freidlin

Pages: 264-281

Published online: 30 Oct 2017

AbstractforQuantitative assessment of a prognostic or predictive biomarker panel | Full Text | References | PDF (1.4 MB)

314 Views
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Article

Biomarker enrichment considerations in oncology early development single-arm studies

Hong Tian & Kevin Liu

Pages: 282-291

Published online: 30 Oct 2017

AbstractforBiomarker enrichment considerations in oncology early development single-arm studies | Full Text | References | PDF (730.1 KB)

264 Views
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Article

On Enrichment Strategies for Biomarker Stratified Clinical Trials

Xiaofei Wang, Jingzhu Zhou, Ting Wang & Stephen L George

Pages: 292-308

Published online: 30 Oct 2017

AbstractforOn Enrichment Strategies for Biomarker Stratified Clinical Trials | Full Text | References | PDF (1.4 MB) | Supplemental

478 Views
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Article

Comparing three regularization methods to avoid extreme allocation probability in response-adaptive randomization

Yining Du, John D. Cook & J. Jack Lee

Pages: 309-319

Published online: 21 Mar 2017

AbstractforComparing three regularization methods to avoid extreme allocation probability in response-adaptive randomization | Full Text | References | PDF (1.2 MB) | Supplemental

216 Views
6 CrossRef citations
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Article

Improving the power to establish clinical similarity in a Phase 3 efficacy trial by incorporating prior evidence of analytical and pharmacokinetic similarity

Donglin Zeng, Jean Pan, Kuolung Hu, Eric Chi & D. Y. Lin

Pages: 320-332

Published online: 27 Nov 2017

AbstractforImproving the power to establish clinical similarity in a Phase 3 efficacy trial by incorporating prior evidence of analytical and pharmacokinetic similarity | Full Text | References | PDF (1.1 MB)

246 Views
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Article

Personalized Risk Prediction in Clinical Oncology Research: Applications and Practical Issues Using Survival Trees and Random Forests

Chen Hu & Jon Arni Steingrimsson

Pages: 333-349

Published online: 19 Oct 2017

AbstractforPersonalized Risk Prediction in Clinical Oncology Research: Applications and Practical Issues Using Survival Trees and Random Forests | Full Text | References | PDF (1.7 MB)

729 Views
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Article

A simulation study on implementing marginal structural models in an observational study with switching medication based on a biomarker

Hyang Kim & Greg Cable

Pages: 350-361

Published online: 04 Dec 2017

AbstractforA simulation study on implementing marginal structural models in an observational study with switching medication based on a biomarker | Full Text | References | PDF (885.6 KB)

321 Views
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Article

Estimating the Optimal Personalized Treatment Strategy Based on Selected Variables to Prolong Survival via Random Survival Forest with Weighted Bootstrap

Jincheng Shen, Lu Wang, Stephanie Daignault, Daniel E. Spratt, Todd M. Morgan & Jeremy M.G. Taylor

Pages: 362-381

Published online: 25 Oct 2017

AbstractforEstimating the Optimal Personalized Treatment Strategy Based on Selected Variables to Prolong Survival via Random Survival Forest with Weighted Bootstrap | Full Text | References | PDF (2.7 MB)

342 Views
8 CrossRef citations
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Book Review

Article

Cancer clinical trials – current and controversial issues in design and analysis

Steven Sun

Pages: 382-383

Published online: 07 Mar 2018

CitationforCancer clinical trials – current and controversial issues in design and analysis | Full Text | References | PDF (180.6 KB)

115 Views
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Journal of Biopharmaceutical Statistics (Vol.28, Iss.2, 2018)

Special Issue: Precision Medicine in Cancer Research

Special Issue: Precision Medicine in Cancer Research

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